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141
Cross-Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity
Published 2018-01-01“…Moreover, studies of germ-free mice have provided evidence that microbiota diversity and the presence of a specific microbe in the gut can affect immune cells in hosts. Therefore, the changes in the composition of the gut microbiota can affect host metabolism and immunity. …”
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142
Natural Hybridization Between <i>Quercus crassipes</i> and <i>Q. crassifolia</i> (Fagaceae) Is a Key Process to Ensure the Biodiversity of Their Associated Lichen Community
Published 2025-01-01“…We conclude that genetic differences between host oaks promoted significantly different lichen communities and that hybrids may act as ecological islands, accumulating lichen species from both parental species and their own novel species. …”
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143
Audio Watermarking Scheme Based on Singular Spectrum Analysis and Psychoacoustic Model with Self-Synchronization
Published 2016-01-01“…In this work, SSA is used to analyze the host signals and to extract the singular spectra. …”
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144
Growth, infection and aggressiveness of Phytophthora pathogens on Rhododendron leaves
Published 2021-06-01“…The genus Rhododendron is of considerable importance to plant regulatory agencies because it is host to many Phytophthora species, most notably, P. ramorum and P. kernoviae. …”
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145
Cell-Type-Specific Differentiation and Molecular Profiles in Skin Transplantation: Implication of Medical Approach for Genetic Skin Diseases
Published 2011-01-01“…In skin transplantation biology, multistage and multifocal damages occur in both grafted donor and perilesional host skin and need to be repaired properly for the engraftment and maintenance of characteristic skin architecture. …”
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146
A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease
Published 2019-01-01“…In this review, we have systemically reviewed the pathogenesis of IBD and highlighted recent advances in host genetic factors, gut microbiota, and environmental factors and, especially, in abnormal innate and adaptive immune responses and their interactions, which may hold the keys to identify novel predictive or prognostic biomarkers and develop new therapies.…”
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147
p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity
Published 2025-01-01“…Recently, p97 has emerged as an important pro-viral host factor and p97 inhibitors are being evaluated as potential antiviral agents. …”
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148
RNA Virus Discovery Sheds Light on the Virome of a Major Vineyard Pest, the European Grapevine Moth (<i>Lobesia botrana</i>)
Published 2025-01-01“…Notably, the presence of a novel phasmavirus, typically associated with mosquitoes, expands the known host range and diversity of this family to moths. …”
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149
Chronic restraint stress affects the diurnal rhythms of gut microbial composition and metabolism in a mouse model of depression
Published 2025-01-01“…Abstract Background Depression is a common mental disorder accompanied by gut microbiota dysbiosis, which disturbs the metabolism of the host. While diurnal oscillation of the intestinal microbiota is involved in regulating host metabolism, the characteristics of the intestinal microbial circadian rhythm in depression remain unknown. …”
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150
Mycobacterium avium Infection of Multinucleated Giant Cells Reveals Association of Bacterial Survival to Autophagy and Cholesterol Utilization
Published 2023-01-01“…While granuloma formation with MGCs is a common feature of mycobacterial infection, the role of MGCs within the granulomas as well as in the host-pathogen interaction is poorly understood. To shed light on the role of MGCs, we established a novel in vitro model utilizing THP-1 cells stimulated with a combination of IFN-γ and TNF-α. …”
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151
Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of Mycobacterium abscessus in macrophages
Published 2025-12-01“…These insights advance our understanding of Mab’s impact on host cell metabolism and propose a novel avenue for therapeutic intervention. …”
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152
Antigenic Complementarity in the Origins of Autoimmunity: A General Theory Illustrated With a Case Study of Idiopathic Thrombocytopenia Purpura
Published 2006-01-01“…We describe a novel, testable theory of autoimmunity, outline novel predictions made by the theory, and illustrate its application to unravelling the possible causes of idiopathic thrombocytopenia purpura (ITP). …”
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153
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.
Published 2025-01-01“…This pan-orthohantavirus model will facilitate progress in the fundamental understanding of pathogenesis and virus-host interactions for orthohantaviruses. Furthermore, it is an invaluable tool for preclinical evaluation of novel candidate pan-orthohantavirus intervention strategies.…”
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154
Expression Profiles of Differentially Expressed Circular RNAs and circRNA–miRNA–mRNA Regulatory Networks in SH-SY5Y Cells Infected with Coxsackievirus B5
Published 2022-01-01“…Additionally, RT-qPCR was used to validate the RNA-seq data, and a circRNA–miRNA–mRNA interaction network was constructed based on two circRNAs, such as hsa_circ_0008378 and novel_circ_0014617, which were associated with the regulation of innate immune response in host cells. …”
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155
Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells
Published 2025-02-01“…Our findings underscore LI0758’s pivotal role in activating MAPK pathways and suggest its potential to modulate the localization and function of host CAAX proteins. Further investigation holds promise for elucidating novel bacteria-host interaction mechanisms and fostering the development of innovative therapies against proliferative enteritis.…”
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156
A paradoxical population structure of var DBLα types in Africa.
Published 2025-02-01“…The var multigene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), central to host-parasite interactions. Genome structure studies have identified three major groups of var genes by specific upstream sequences (upsA, B, or C). …”
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157
Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Published 2015-01-01“…Inflammatory bowel disease (IBD) including Crohn’s disease and ulcerative colitis is often precipitated by an abnormal immune response to microbiota due to host genetic aberrancies. Recent studies highlight the importance of the host genome and microflora interactions in the pathogenesis of mucosal inflammation including IBD. …”
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158
Rumen DNA virome and its relationship with feed efficiency in dairy cows
Published 2025-01-01“…Additionally, 2,232 vOTU-host metagenome-assembled genome (hMAG) linkages were predicted, with Firmicutes_A (33.60%) and Bacteroidota (33.24%) being the most prevalent host phyla. …”
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159
Three new species of Apiospora (Amphisphaeriales, Apiosporaceae) in China
Published 2025-01-01“…The genus Apiospora is commonly used as plant pathogens, endophytes, and saprophytes, which are widely present in various host ranges around the world. The discovery of metabolites has been proven to play an important role in the pharmaceutical industry. …”
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160
THE SPECIFICS OF TRANSLATING THE FICTIONAL LANGUAGE "NADSAT" INTO FRENCH
Published 2024-12-01“…One of the most striking examples of the use of a fictional language in fiction is Anthony Burgess's novel A Clockwork Orange, in which the author creates a unique "conlang" known as "nadsat". …”
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