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Novel drug targets for monkeypox: From viral to host proteins
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Exploring the recombinant evolution and hosts of crucivirus based on novel oyster-associated viruses
Published 2025-02-01“…This study identifies seven novel crucivirus genomes from oysters cultivated along the coast of the South China Sea. …”
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Novel Bioceramic Urethral Bulking Agents Elicit Improved Host Tissue Responses in a Rat Model
Published 2016-01-01“…To test the physical properties and host response to the bioceramic particles, silica-calcium phosphate (SCPC10) and Cristobalite, in a rat animal model and compare their biocompatibility to the current clinically utilized urethral bulking materials. …”
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Novel primers improve species delimitation in Cercospora
Published 2018-12-01“…Because several taxa have broader host ranges, reliance on host data in Cercospora taxonomy has proven problematic. …”
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Effects of Microbes on Insect Host Physiology and Behavior Mediated by the Host Immune System
Published 2025-01-01“…Studying the insect immune system can aid in identifying novel insecticide targets and provide insights for developing novel pest control strategies. …”
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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department
Published 2020-04-01“…Current diagnostic and prognostic solutions, including procalcitonin, lack required accuracy. A novel blood-based host response test, HostDx™ Sepsis by Inflammatix, Inc., assesses the likelihood of a bacterial infection, the likelihood of a viral infection, and the severity of the condition. …”
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Bacterial metabolism in the host and its association with virulence
Published 2025-12-01“…The knowledge of crosslinked metabolic pathways of bacteria and their host will serve to develop novel potential therapeutics.…”
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Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae
Published 2025-02-01Subjects: Get full text
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Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction
Published 2015-01-01“…Genomic analyses have uncovered remarkable coevolution between the human host and H. pylori. Perturbation of this coevolution results in dysregulation of the host-pathogen interaction, leading to oncogenic effects. …”
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Candida Biofilms and the Host: Models and New Concepts for Eradication
Published 2012-01-01“…The host-biofilm interactions are also discussed, together with their potential applications in Candida biofilm elimination.…”
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Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions
Published 2017-01-01“…Further development and application of technologies for genome-wide identification of extracellular protein interactions will be important in deciphering functional host-pathogen interaction networks, laying the foundation for development of novel therapeutics.…”
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Host RNA-Binding Proteins as Regulators of HIV-1 Replication
Published 2024-12-01“…During HIV-1 infection, these proteins are key players in the fine-tuning of viral and host cellular and molecular pathways, including (but not limited to) viral entry, transcription, splicing, RNA modification, translation, decay, assembly, and packaging, as well as the modulation of the antiviral response. …”
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Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients
Published 2021-01-01“…Acute graft-versus-host disease (aGvHD) is a rare complication of liver transplantation associated with high morbidity and mortality. …”
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Dual Control of Host Actin Polymerization by a Legionella Effector Pair
Published 2024-01-01“…Host actin cytoskeleton is often targeted by pathogenic bacteria through the secretion of effectors. …”
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Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function...
Published 2025-02-01“…Further study suggested that XR_001919077.1 acted as a sponge of Chi-miR-93-5p to promote the expression of sirt1, and the XR_001919077.1/Chi-miR-93-5p/sirt1 axis significantly delayed the in vitro growth of N. caninum in caprine EECs by regulating host cell mitochondrial function and autophagy. Our findings provide a novel insight to understand the interactions between N. caninum and host cells.IMPORTANCEThe uterus is an indispensable reproductive organ for embryo implantation and fetal growth. …”
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A mutualism-parasitism system modeling host and parasite withmutualism at low density
Published 2012-02-01“…Our aim is to show that mutualism at low density promotes coexistence of the species and leads to high production of the prey (host). The mutualism-parasitism system presented here is a combination of the Lotka-Volterra cooperative model and Lotka-Volterra predator-prey model. …”
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A phylogenetic epidemiology approach to predicting the establishment of multi-host plant pests
Published 2025-01-01“…Analysts can adapt these phylogenetic ecology tools to predict spread of any multi-host pest in novel habitats.…”
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How hosts and pathogens choose the strengths of defense and counterdefense: a game-theoretical view
Published 2025-01-01“…Host–pathogen interactions consist of an attack by the pathogen, frequently a defense by the host and possibly a counterdefense by the pathogen. …”
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