Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome by Karen Kelley, Shin-Ju E. Chang, Shi-Lung Lin

“…After transcription, the trinucleotide repeats can fold into RNA hairpins and are further processed by Dicer endoribonuclases to form microRNA (miRNA)-like molecules that are capable of triggering targeted gene-silencing effects in the TREDs. …”
Get full text

Tuning of Water Vapor Permeability in 2D Nanocarbon-Based Polypropylene Composite Membranes by Glykeria A. Visvini, Georgios N. Mathioudakis, Amaia Soto Beobide, George A. Voyiatzis

“…The presence of either GO, rGO or GNPs in the new polyolefin composite membranes revealed 6- to 7-fold enhanced WVP values compared to pristine PP. …”
Get full text

Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis. by Noelle M Nieskens, Yukiko Miyamoto, Brianna M Hurysz, Anthony J O'Donoghue, Lars Eckmann

“…Consequently, an urgent need exists for the development of novel drug entities against trichomoniasis. Critical for antimicrobial drug development is the demonstration of in vivo efficacy. …”
Get full text

Development of a Confocal Optical System Design for Molecular Imaging Applications of Biochip by Guoliang Huang, Shukuan Xu, Jiang Zhu, Cheng Deng, Zhonghua Dong, Yang Yang, Xiaoyong Yang, Xianhua Wang, Guofan Jin

“…A novel confocal optical system design and a dual laser confocal scanner have been developed to meet the requirements of highly sensitive detection of biomolecules on microarray chips, which is characterized by a long working distance (wd>3.0 mm), high numerical aperture (NA=0.72), and only 3 materials and 7 lenses used. …”
Get full text

Robust dual-tone multi-frequency tone detection using k-nearest neighbour classifier for a noisy environment by Arunit Maity, P. Prakasam, Sarthak Bhargava

“…Design/methodology/approach – A novel machine learning-based approach to detect DTMF tones affected by noise, frequency and time variations by employing the k-nearest neighbour (KNN) algorithm is proposed. …”
Get full text

The role of delays in innate and adaptive immunity to intracellular bacterial infection by Simeone Marino, Edoardo Beretta, Denise E. Kirschner

“…The immune response in humans is complex and multi-fold. Initially an innate response attempts to clear any invasion by microbes. …”
Get full text

Optical semantic communication through multimode fiber: from symbol transmission to sentiment analysis by Zheng Gao, Ting Jiang, Mingming Zhang, Hao Wu, Ming Tang

“…Abstract We propose and validate a novel optical semantic transmission scheme using multimode fiber (MMF). …”
Get full text

Prediction of COVID-19 Confirmed, Death, and Cured Cases in India Using Random Forest Model by Vishan Kumar Gupta, Avdhesh Gupta, Dinesh Kumar, Anjali Sardana

“…A novel coronavirus (SARS-CoV-2) is an unusual viral pneumonia in patients, first found in late December 2019, latter it declared a pandemic by World Health Organizations because of its fatal effects on public health. …”
Get full text

Toxicity and Bioremediation of Heavy Metals Contaminated Ecosystem from Tannery Wastewater: A Review by Bernard E. Igiri, Stanley I. R. Okoduwa, Grace O. Idoko, Ebere P. Akabuogu, Abraham O. Adeyi, Ibe K. Ejiogu

“…The use of biofilm has showed synergetic effects with many fold increase in the removal of heavy metals as sustainable environmental technology in the near future.…”
Get full text

Using microscopic imaging and ensemble deep learning to classify the provenance of archaeological ceramics by Qian Wang, Xuan Xiao, Zi Liu

“…The experiments employ accuracy, precision, recall and F1 score criteria to offer a comprehensive of the classification outcomes. Under 5-fold cross-validation and independent testing, the proposed fusion-based model performed excellently after comparing above three typical deep learning model. …”
Get full text

Combining machine learning and single-cell sequencing to identify key immune genes in sepsis by Hao Wang, Linghan Len, Li Hu, Yingchun Hu

“…Abstract This research aimed to identify novel indicators for sepsis by analyzing RNA sequencing data from peripheral blood samples obtained from sepsis patients (n = 23) and healthy controls (n = 10). 5148 differentially expressed genes were identified using the DESeq2 technique and 5636 differentially expressed genes were identified by the limma method(|Log2 Fold Change|≥2, FDR < 0.05). …”
Get full text

Supramolecular Assembly and Reversible Transition and of Chitosan Fluorescent Micelles by Noncovalent Modulation by An Liu, Hong Song, Puyou Jia, Ying Lin, Qingping Song, Jiangang Gao

“…This study provides novel multifunctional materials that are of great importance for their potential application in the fields of optoelectronic devices and chemical and biomedical sensors.…”
Get full text

Grid Forming Inverter With Increased Short-Circuit Contribution to Address Inverter-Based Microgrid Protection Challenges by Maximiliano Ferrari, Leon M. Tolbert, Emilio C. Piesciorovsky

“…The contribution of this article is two-fold. The first innovation proposes specific hardware modifications to grid-forming inverters to increase their short-circuit current during electrical faults. …”
Get full text

Going Down Textual Lane: Ibadan in Text and Thoughts: A Review of Under the Brown Rusted Roofs by Abimbola Adunni Adelakun. Published by Kraftgriots, Ibadan, 2008, 252pp.1 by Kole Odutola

“… As a child born and battered (not buttered) in Lagos, my thoughts about Ibadan people are three-fold. I think of a different accent when they speak English. …”
Get full text

Multimodal Autism Spectrum Disorder Method Using GCN With Dual Transformers by Tianming Song, Zhe Ren, Jian Zhang, Yawei Qu, Yingying Cui, Zhengda Liang

“…This study proposes a novel diagnostic approach that integrates Graph convolutional networks (GCN) with dual transformer architectures, optimized through a Co-training strategy. …”
Get full text

Evaluation of nano-sized virgin coconut oil (VCO)-loaded liposomes for enhancing mushroom and B16-F10 tyrosinase activity by Suwipa Ungphaiboon, Sutasinee Ardhanwanich, Duangkhae Maneenuan, Sirirat Pinsuwan, Pawika Mahasawat

“…Encapsulation of VCO enhanced mushroom tyrosinase activity by 3-fold and exhibited lower cytotoxicity to B16-F10 cells compared to VCO alone. …”
Get full text

High-Q Fabry-Pérot Cavity Based on Micro-Lens Array for Refractive Index Sensing by Qi Wang, Xuyang Zhao, Man Luo, Yuxiang Li, Junjie Liu, Xiang Wu

“…In this work, we presented a novel approach that utilized the soft lithography and imprinting technology to incorporate the convex micro-lens array structure into the FP (FP-lens) cavity. …”
Get full text

Drug-drug interaction between ensitrelvir and tacrolimus in a patient undergoing treatment for COVID-19: a case report by Yuki Miyata, Ryo Yamaguchi, Takehito Yamamoto, Toshiyuki Kishida, Kazuhiko Ikeuchi, Hiroaki Harada, Takeya Tsutsumi, Keishi Fujio, Tappei Takada

“…Abstract Background Ensitrelvir is a novel SARS-CoV-2 3-chymotrypsin-like protease inhibitor, similar to nirmatrelvir/ritonavir. …”
Get full text

Urine proteomics defines an immune checkpoint-associated nephritis signature by Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong

“…We identified several novel urine biomarkers, including IL-5, Fas, TNFSF4, CD274, IL-20, TNFSF15, TSLP, TREM1 and CCL1 while confirming previously reported markers such as CXCL9 and TNF-α. …”
Get full text

Travoprost Intracameral Implant in Eyes with Glaucoma or Ocular Hypertension: Early Short-Term Real-World Outcomes by Teymoorian S, Kaur J

“…This publication is the first real-world study in the literature to-date on this novel technology.Keywords: medication, pharmaceutical, implant, prostaglandin, glaucoma, iDose…”
Get full text