Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients by Wang M, Tang J, Pan Z, Jiang H, Hu D, Zhu B, Liang Z, Zhao X, Li Y

“…Our team’s work demonstrates that the novel Li anesthetic protocol (strategic anesthesia management of remifentanil combined with propofol and effective respiratory support through MRHC and jaw thrust, increased oxygen reserve via a novel mask) for obesity for painless gastroscopy with lacking advanced airway management devices is safe and efficient. …”
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Accurately Tunable AuNC‐ZIF Content Architecture Based on Coordination‐Dissociation Mechanism Enables Highly Brightness Dual‐Site Fluorescent Biosensor by Junyang Chen, Yuqian Wang, Runpu Shen, Wei Li, Sainan Gao, Zhikang Xiao, Qiyan Lv, Xiaojie Song, Jianzhong Xu, Gaoxiang Xu, Huifang Cui, Zhaohui Li

“…The surface of ZIF‐8 induces a confinement effect on the configuration and electrons of AuNCs, significantly enhancing luminescence (18‐fold increase). The quantum yield of AuNCs exhibits an increase of more than 13‐fold, from 2.80% to 38.1%. …”
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Human Action Recognition Using Difference of Gaussian and Difference of Wavelet by Gopampallikar Vinoda Reddy, Kongara Deepika, Lakshmanan Malliga, Duraivelu Hemanand, Chinnadurai Senthilkumar, Subburayalu Gopalakrishnan, Yousef Farhaoui

“…The major challenge in HAR is the design of an action descriptor that makes the HAR system robust for different environments. A novel action descriptor is proposed in this study, based on two independent spatial and spectral filters. …”
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Foliar application of nano biochar solution elevates tomato productivity by counteracting the effect of salt stress insights into morphological physiological and biochemical indice... by Javeria Shahzadi, Zaib-un-Nisa, Naila Ali, Muhammad Iftikhar, Anis Ali Shah, M. Yasin Ashraf, Chen Chao, Shifa Shaffique, Mansour K. Gatasheh

“…Abstract Nano-biochar considers a versatile and valuable sorbent to enhance plant productivity by improving soil environment and emerged as a novel solution for environmental remediation and sustainable agriculture in modern era. …”
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Calcium Activation of the Androgen Receptor in Prostate Cells by Zeina W. Sharawi, Sawsan M. Khatrawi, Qiaochu Wang, Hongzhao Zhou, Kedra Cyrus, Gai Yan, Becky Hoxter, Bassem R. Haddad, Mary Beth Martin

“…Taken together, the results suggest a novel role of calcium in the castration-resistant phenotype.…”
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DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts by Richard G. Federley, Louis J. Romano

“…Most DNA polymerases have a similar three dimensional fold, akin to a human right hand, despite differences in sequence homology. …”
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Microspectrometer-Enabled Real-Time Concentration Monitoring in the Microfluidic Protein Enrichment Chip by Dong-Li Li, Wen-Shu Huang, Yi Hung Wu, Chun-Ping Jen

“…This study presents a novel microspectrometer-integrated microfluidic system for real-time protein concentration monitoring. …”
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Biomass and Yield in Solanum lycopersicum Expressing a Synthetic Photorespiration Pathway by Laura Dougherty, Bret Cooper, James Bunce, Bryan Vinyard, John Stommel

“…The number of fruit was similarly greater (1.4- to 4.2-fold) in modified plants; however, average individual fruit weights were significantly less for all but one line. …”
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Accelerated dynamic light sheet microscopy: unifying time-varying patterned illumination and low-rank and sparsity constrained reconstruction by Marco Tobia Vitali, Alessia Candeo, Andrea Farina, Paolo Pozzi, Alessia Brix, Andrea Bassi, Teresa M Correia

“…This method was applied to the volumetric imaging of embryonic zebrafish hearts, achieving an improvement in imaging speed of 4-fold compared to standard LSFM and a 2-fold improvement compared to traditional compressed sensing approaches, while preserving reconstruction accuracy and enabling the visualization of fast dynamic events with a resolution of a few tens of milliseconds. …”
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Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone... by Heather E. Owston, Payal Ganguly, Giuseppe Tronci, Stephen J. Russell, Peter V. Giannoudis, Elena A. Jones

“…Periosteal colonies were more homogenous in size (range 2-30 mm2 vs. 2-54 mm2) and on average 2500-fold more frequent (2.0% vs. 0.0008%, n=10, P=0.004) relative to total viable cells. …”
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Optimized extraction and kinetic study of cholesterol oxidase from a newly isolated Escherichia fergusonii strain from local whey samples: insights through a combined experimental... by Simin Khataee, Gholamreza Dehghan, Samaneh Rashtbari, Arezu Marefat, Sina Jamei, Hamed Farzi-Khajeh

“…This study aimed to isolate a novel ChoX-producing bacterial strain from whey samples. …”
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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

“…Modern labelling techniques, in this case the [11C]MeLi cross-coupling methodology, expands labelling opportunities, allowing to explore novel vesamicol-based structures as potential PET-tracers. …”
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Applications of Self-Assembled Monolayers in Surface-Enhanced Raman Scattering by Charles K. Klutse, Adam Mayer, Julia Wittkamper, Brian M. Cullum

“…Specific examples are based on novel multilayered SERS substrates developed in the author’s laboratory where SAMs have been demonstrated as excellent dielectric spacers for improving SERS enhancement more than 20-fold relative to conventional single layer SERS substrates. …”
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Event-Based Clustering Architecture for Power Efficiency in Wireless Sensor Networks by Kai-Ting Yang, Wei Kuang Lai, Shu-Min Li, Yuh-Chung Lin

“…Therefore, power efficiency is very important for a WSN. For this, a novel architecture is presented in this paper. The proposed architecture categorizes sensors into different clusters by events. …”
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A CNN-Based Microwave Imaging System for Detecting Watermelon Ripeness by Zachary M. Choffin, Lingyan Kong, Yu Gan, Nathan Jeong

“…The results show 86% accuracy for ripeness classification in three fold cross validation. This novel approach demonstrates the potential of combining microwave imaging with machine learning for non-destructive food quality assessment, offering a scalable and reliable tool for real-time evaluation of fruit ripeness and quality.…”
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Improved jet lag recovery is associated with a weaker molecular biological clock response around the time of expected activity onset by Marie-Claire Boutrin, Melissa E. S. Richardson, Feyikemi Oriola, Samira Bolo

“…The further addition of light during the jet lag recovery period reduced typical changes in circadian gene expression in the SCN to minimal levels under both LD cycles.DiscussionThis study uncovers a novel explanation for the impact of multiple disruptive light exposures on gene expression of the molecular SCN clock in the brain.…”
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Cooperative Identification of Prolonged Motor Movement From EEG for BCI Without Feedback by Alicia Falcon-Caro, Joao Filipe Ferreira, Saeid Sanei

“…This paper presents a novel approach for recognition of prolonged motor movements from a subject’s electroencephalogram (EEG) using orthogonal functions to model a sequence of sub-gestures. …”
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Removal of Hg from Real Polluted Sediments Using Enhanced-EK Decontamination: Verification of Experimental Methods and Batch-Test Preliminary Results by Danilo Malarbì, Pietro P. Falciglia, Federico G. A. Vagliasindi

“…In this work, data from batch-tests using different novel biosurfactant agents were reported. In addition, a dedicated EK bench-scale apparatus was designed and carried out. …”
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Protein identification using Cryo-EM and artificial intelligence guides improved sample purification by Kenneth D. Carr, Dane Evan D. Zambrano, Connor Weidle, Alex Goodson, Helen E. Eisenach, Harley Pyles, Alexis Courbet, Neil P. King, Andrew J. Borst

“…This issue is particularly problematic for self-assembling protein nanomaterials, where unexpected geometries may reflect novel assembly states, cross-contamination, or native proteins originating from the expression host. …”
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Linking machine learning and biophysical structural features in drug discovery by Armin Ahmadi, Shivangi Gupta, Vineetha Menon, Jerome Baudry

“…By leveraging pharmacophore descriptors, the AI/ML framework prioritized features uniquely associated with ligand-selected conformations, enabling a mechanism-driven understanding of binding interactions. This novel approach integrates biophysical insights with machine learning, focusing on pharmacophoric properties such as charge, hydrogen bonding, hydrophobicity, and aromaticity.ResultsResults showed significant enrichment of true positive ligands—improving database enrichment by up to 54-fold compared to random selection—demonstrating the robustness of this approach across diverse proteins.ConclusionUnlike conventional structure-based or ligand-based screening methods, this work emphasizes the role of specific protein conformations in driving ligand binding, making the process highly interpretable and actionable for drug discovery. …”
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