A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation by Rodolfo Moreno-Fuquen, Juan F. Avellaneda-Tamayo, Kevin Arango-Daraviña, Javier Ellena, Alan R. Kennedy

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Development and validation of a novel AI-derived index for predicting COPD medical costs in clinical practice by Guan-Heng Liu, Chin-Ling Li, Chih-Yuan Yang, Shih-Feng Liu

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Cross-species comparison of AlphaFold-derived G protein-coupled receptor structures reveals novel melatonin-related receptor in Neurospora crassa. by Cathryn S D Maienza, Guillaume Lamoureux, Kwangwon Lee

“…This proof-of-concept study underscores the potential of N. crassa as a model organism for circadian research and demonstrates the broader applicability of using AlphaFold2, especially when sequence similarity does not lead to candidate genes, for identifying novel receptors across different species.…”
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Automatic Segmentation of High Speed Video Images of Vocal Folds by Turgay Koç, Tolga Çiloğlu

“…An automatic method for segmenting glottis in high speed endoscopic video (HSV) images of vocal folds is proposed. The method is based on image histogram modeling. …”
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Unfolder: fast localization and image rectification of a document with a crease from folding in half by A.M. Ershov, D.V. Tropin, E.E. Limonova, D.P. Nikolaev, V.V. Arlazarov

“…While there are many geometrical rectification methods, they were usually developed for arbitrary bends and folds. We consider such algorithms and propose a novel approach Unfolder developed specifically for images of documents with a crease from folding in half. …”
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NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation by Yuki Kagaya, Zicong Zhang, Nabil Ibtehaz, Xiao Wang, Tsukasa Nakamura, Pranav Deep Punuru, Daisuke Kihara

“…To address this challenge, we developed NuFold, a novel computational approach that leverages state-of-the-art deep learning architecture to accurately predict RNA tertiary structures. …”
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Folded pseudochiral Fermi surface in 4Hb-TaSe2 from band hybridization with a charge density wave by Matthew D. Watson, Andrea Tonelli, Mugerabe Zerabza, Sam Hayward, Rebecca Wilkinson, Ettore Carpene, Cephise Cacho, Valentina De Renzi, Simon Crampin, Enrico Da Como

“…Abstract Stacking of strongly-correlated 2D materials is opening the possibility to demonstrate novel electronic or magnetic ordering phenomena. …”
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Design of Analog Signal Processing Applications Using Carbon Nanotube Field Effect Transistor-Based Low-Power Folded Cascode Operational Amplifier by Varsha S. Bendre, A. K. Kureshi, Saurabh Waykole

“…Simulation results show that the proposed applications are properly implemented using novel folded cascode operational amplifier (FCOA) implemented using CNFET.…”
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Design of a humanized CD40 agonist antibody with specific properties using AlphaFold2 and development of an anti-PD-L1/CD40 bispecific antibody for cancer immunotherapy by Kun Du, He Huang

“…It also demonstrates that the current AlphaFold2(AlphaFold2-Multimer) can predict antibody-antigen complexes. …”
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Novel Miniaturized Octaband Antenna for LTE Smart Handset Applications by Haixia Liu, Bo Lu, Long Li

“…A novel octaband LTE mobile phone antenna is presented, which has a compact size with the overall dimension of 35 mm × 9 mm × 3 mm. …”
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A Novel Murine Model for the In Vivo Study of Transdermal Drug Penetration by Gábor Eros, Petra Hartmann, Szilvia Berkó, Eszter Csizmazia, Erzsébet Csányi, Anita Sztojkov-Ivanov, István Németh, Piroska Szabó-Révész, István Zupkó, Lajos Kemény

“…Our aim was to establish a novel in vivo experimental model which provides a possibility for exact measurement of the quantity of penetrated drug. …”
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Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy by Axel H. Schönthal

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A Novel MEGNet for Classification of High-Frequency Oscillations in Magnetoencephalography of Epileptic Patients by Jun Liu, Siqi Sun, Yang Liu, Jiayang Guo, Hailong Li, Yuan Gao, Jintao Sun, Jing Xiang

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PCMMD: A Novel Dataset of Plasma Cells to Support the Diagnosis of Multiple Myeloma by Caio L. B. Andrade, Marcos V. Ferreira, Brenno M. Alencar, Jorge L. S. B. Filho, Matheus A. Guimaraes, Iarley Porto Cruz Moraes, Tiago J. S. Lopes, Allan S. dos Santos, Mariane M. dos Santos, Maria I. C. S. e Silva, Izabela M. D. R. P. Rosa, Gilson C. de Carvalho, Herbert H. M. Santos, Márcia M. L. Santos, Roberto Meyer, Luciana M. P. B. Knop, Songeli M. Freire, Ricardo A. Rios, Tatiane N. Rios

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The protein structurome of Orthornavirae and its dark matter by Pascal Mutz, Antonio Pedro Camargo, Harutyun Sahakyan, Uri Neri, Anamarija Butkovic, Yuri I. Wolf, Mart Krupovic, Valerian V. Dolja, Eugene V. Koonin

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A Novel Space Large Deployable Paraboloid Structure with Power and Communication Integration by Tao Zheng, Zheng Fei, Xi Rui, Lide Yan

“…Finally, deploying experiments of the folded hoop of the CMMR and sun tracking experiments of the TER pointing mechanism on the ground were carried out successfully, which proves that the folded hoop can be deployed successfully with fairly high deploying dependability, and the TER pointing mechanism is feasible for the SSPCI from the mechanism principle and the control mode in space applications indirectly. …”
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Impact of Novel Resistance Profiles in HIV-1 Reverse Transcriptase on Phenotypic Resistance to NVP by Liyan Jiao, Hanping Li, Lin Li, Daomin Zhuang, Yongjian Liu, Zuoyi Bao, Siyang Liu, Jingyun Li

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Purification, Characterization, and Biocatalytic and Antibiofilm Activity of a Novel Dextranase from Talaromyces sp. by Mahasen Mohamed Ahmed Ebaya, Mohammed El-Mowafy, Mohamed Mohamed Adel El-Sokkary, Ramadan Hassan

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Trends in novel antiandrogen receptor signal inhibitor use and medical costs in prostate cancer by Hikari Miura, Hayato Yamamoto, Yoshiharu Okuyama, Noritaka Ishi, Ryuma Tanaka, Takuya Oishi, Fumiya Yoneyama, Tomoko Hamaya, Kyo Togashi, Naoki Fujita, Teppei Okamoto, Chikara Ohyama, Shingo Hatakeyama

“…Abstract Objective We aimed to examine trends in novel antiandrogen receptor signal inhibitor (ARSI) usage and medical costs by collecting real‐world big data included in The National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) Open Data, covering most of the clinical practices throughout Japan. …”
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Pseudodominant Nanophthalmos in a Roma Family Caused by a Novel PRSS56 Variant by Lubica Dudakova, Pavlina Skalicka, Olga Ulmanová, Martin Hlozanek, Viktor Stranecky, Frantisek Malinka, Andrea L. Vincent, Petra Liskova

“…We have identified pseudodominant inheritance for this phenotype caused by a novel variant in PRSS56, representing a possible founder effect. …”
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