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KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitors
Published 2025-01-01“…Results Analysis of 13 studies involving 1132 patients highlighted the significant efficacy of KRAS-G12C inhibitor monotherapy, particularly among elderly and female patients. Treatment response was notably affected by liver and brain metastases, with KEAP1 mutations identified as a primary negative prognostic factor, closely associated with early resistance to treatment. …”
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103
Age-dependent differences in the association between blood interleukin-6 levels and mortality in patients with sepsis: a retrospective observational study
Published 2025-01-01“…The patients were categorized into two groups: non-elderly (< 70 years) and elderly (≥ 70 years). Associations between log-transformed blood IL-6 levels and 28-day in-hospital mortality (primary outcome) and multiple organ dysfunction (MOD) on days 3 and 7 (secondary outcomes) were examined. …”
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104
Pola Tekanan Darah Pada Lansia di Posyandu Lansia Kelurahan Padang Pasir Padang Januari 2014
Published 2015-01-01“…The study was conducted elderly at Padang Pasir elderly intergrated health post in January 2014. …”
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105
Les bailleurs sociaux français face au vieillissement dans les années 2000 et le recours aux labellisations
Published 2020-11-01“…An increasing number of French social housing organizations are developing business strategies for elderly tenants through adapted housing or extra services, some of which rely upon certifications evaluated by independent third-parties. …”
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106
Emploi des « seniors » et conditions de travail : une étude statistique comparative entre pays d’Europe
Published 2011-05-01“…Employment rates of ageing workforce have become a major concern, in particular for international organisms. In this article we analyze the links between work constraints and employment of elderly, by comparing various European countries. …”
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107
Evaluation of furniture used by old people in sitting
Published 2014-10-01“…A plurality of furniture was found and organized into five different categories. All categories presented inadequacies: 100% of furniture was appropriate concerning seat width, but only 24% were in compliance with their height and 80% in inadequate seat depth measurement. 52% of the evaluated furniture presented some type of adjustment made by the elderly to improve their posture and / or feel more comfortable when sitting. …”
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Characterization of older adults' sexual life in a health area
Published 2023-02-01“…More than 90 % of men have some difficulty in sexual life. 22.5% present difficulties due to organic diseases.<br /><strong>Conclusions:</strong> it is false that the elderly is an entity devoid of interest in sexual life, but it is affected by several factors, among which organic diseases and lack of a partner stand out.…”
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Accumulation of Deficits as a Proxy Measure of Aging
Published 2001-01-01“…This paper develops a method for appraising health status in elderly people. A frailty index was defined as the proportion of accumulated deficits (symptoms, signs, functional impairments, and laboratory abnormalities). …”
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110
A Stochastic Approach to Modeling Food Pattern
Published 2022-01-01“…This process quantifies the exposure to toxins of subjects living with comorbidity (children not breastfed, the elderly, and pregnant women) to food-borne diseases. …”
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Everolimus for Compassionate Use in Multiple Basal Cell Carcinomas
Published 2013-01-01“…Everolimus is an inhibitor of the mammalian target of rapamycin (mTOR) and has been shown to have antineoplastic activity in addition to its use as an immunosuppressive agent for the prevention of organ transplant rejection. We report the use of everolimus for the compassionate treatment of four elderly, nontransplant patients presenting with multiple basal cell carcinomas (BCC). …”
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Analysis of solving methods and complexity of algorithmics problems in Lithuanian and Baltic Olympiads
Published 2003-12-01“… Lithuanian Olympiads in Informatics are being organized since 1990. Each Olympiad consists of three rounds. …”
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113
Quand l’injonction à la sollicitude appauvrit le travail émotionnel
Published 2024-06-01“…While most academic research on care work shows that it struggles to be socially and economically recognized, home help organizations for the elderly seem, on the contrary, to be appropriating the notion of care in their practice and communications. …”
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Designing and evaluating tourism experiences in senior mobility: An application of the OEC framework
Published 2020-10-01“…This research was developed in the frame of the VOLTO JÁ Project, which aims to implement a senior social exchange program in Portugal, among social economy organizations to promote tourism experiences for the elderly. …”
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Age-Related Changes in Trabecular and Cortical Bone Microstructure
Published 2013-01-01“…Aging is a complex process, and the effects of aging are myriad and insidious, leading to progressive deterioration of various organs, including the skeleton. Age-related bone loss and resultant osteoporosis in the elderly population increase the risk for fractures and morbidity. …”
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Periodontal Care as a Fundamental Step for an Active and Healthy Ageing
Published 2013-01-01“…This group is known as the young elderly. On the contrary, a consistent part of seniors develops a greater number of medical conditions and become more and more dependent, these are the old elderly. …”
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Motion – Helicobacter pylori Causes or Worsens GERD: Arguments against the Motion
Published 2002-01-01“…Although the relationship between H pylori and gastric physiology is complex, the organism has little effect on acid secretion in most North American or Western European subjects, and has a net suppressive effect, especially in elderly subjects, in other parts of the world. …”
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Quality of life assessment of the older population at the substantiation of active longevity strategies in the context of structural demographic changes
Published 2019-04-01“…The results of studies to assess the quality of life, the rule-making activities of international organizations to ensure active longevity have been summarized in the article. …”
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Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
Published 2011-01-01“…Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. …”
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Association between ethylene oxide exposure and cognitive function in older adults from NHANES data
Published 2025-01-01“…Abstract Ethylene Oxide (EO), a volatile organic compound, has garnered considerable attention for its potential impact on human health. …”
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