Research and Application Progress of Dual-energy CT in Prostate Lesions by Yize LI, Ziqi CHEN, Luyao ZHANG, Yingmin CHEN

“…Prostate lesions are common in middle-aged and elderly men. Dual-energy CT (DECT) can capture projection data at high and low X-ray energies in a single scan, significantly enhancing its ability to differentiate substances compared with traditional CT. …”
Get full text

Successful Management of Immune Thrombocytopenia Presenting with Lethal Alveolar Hemorrhage by Keiki Nagaharu, Masahiro Masuya, Keiki Kawakami, Naoyuki Katayama

“…We report the case details of three elderly ITP patients presenting with lethal diffuse alveolar hemorrhage. …”
Get full text

Aging, cancer, and autophagy: connections and therapeutic perspectives by Begoña Zapatería, Esperanza Arias, Esperanza Arias

“…Aging and cancer are intricately linked through shared molecular processes that influence both the onset of malignancy and the progression of age-related decline. As organisms age, cellular stress, genomic instability, and an accumulation of senescent cells create a pro-inflammatory environment conducive to cancer development. …”
Get full text

The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases by Margarete Dulce Bagatini, Alessandra Antunes dos Santos, Andréia Machado Cardoso, Aline Mânica, Cristina Ruedell Reschke, Fabiano Barbosa Carvalho

“…These diseases strike from children to elderly and are generally characterized by progressive deterioration of cells, eventually leading to tissue or organ degeneration. …”
Get full text

New Role of Quinolones in Respiratory Tract Infections by Ronald F Grossman

“…Because of limited activity of the standard quinolones such as ciprofloxacin and ofloxacin against some clinically important organisms including Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus, new quinolones have been developed. …”
Get full text

The Hereditary Hyperferritinemia-Cataract Syndrome in 2 Italian Families by Katia Perruccio, Francesco Arcioni, Carla Cerri, Roberta La Starza, Donatella Romanelli, Ilaria Capolsini, Maurizio Caniglia

“…The HFE gene H63D mutation underlies Hereditary Haemochromatosis (HH), which needs treatment to prevent organ damages by iron overload. HHCS was definitively diagnosed in all three children. …”
Get full text

Speaking of Animals: A Conceptual analysis of Animal Metaphors in Yoruba by Oluwadamilare Adisa

“…These metaphors were then analyzed, organized and categorized according to Lakoff and Johnson’s Idealized Cultural or Cognitive Metaphor (ICM) framework. …”
Get full text

Single-cell transcriptome atlas of male mouse pituitary across postnatal life highlighting its stem cell landscape by Silke De Vriendt, Emma Laporte, Berkehür Abaylı, Julie Hoekx, Florian Hermans, Diether Lambrechts, Hugo Vankelecom

Get full text

Mechanistic insights toward progress in alogliptin beyond glycemic control: translational perspective by Faraha Ahmed, Syed Sufian Ahmad, M. Mumtaz Alam, M. Shaqiquzzaman, Abul Kalam Najmi, Mohammad Ahmed Khan

“…It has a good safety profile, well-tolerated in elderly patients and in patients with co-morbid conditions including risks of cardiovascular event, renal or hepatic insufficiency. …”
Get full text

Bladder Tumor in Women with Microscopic Hematuria: An Iranian Experience and a Review of the Literature by Shahin Abbaszadeh, Saeed Taheri, Mohammad Hossein Nourbala

“…Patients with a history of gross hematuria or coagulation disorders, having organic diseases, urinary stones, urinary tract infections, nephrological diseases, and local lesions such as urethral caruncle were excluded from the study population. …”
Get full text

COVID-19 Severity According to Age Groups in an Ecuadorian Hospital by Lina Espinoza Neri-Pire, Freddy Fernando Jumbo Salazar, Jenny Olivia Caicedo Rodríguez

“…<strong>Foundation:</strong> an increment in the COVID-19 severity has been observed with increasing age. Elderly people are more susceptible to suffer severity during SARS-CoV-2 infection due to weak immunity and other organ dysfunctions. …”
Get full text

Elective incisional hernia repair: lower risk of postoperative wound infection with laparoscopic versus open repair by Serene Si Ning Goh, Kaushal Amitbhai Sanghvi, Aaryan Nath Koura, Jaideepraj Krishnaraj Rao, Aung Myint Oo

“…Results: There were 174 eligible patients. The majority were elderly Chinese women who were overweight. Open repair was performed in 49.4% of patients, while 50.6% underwent laparoscopic repair. …”
Get full text

To Measure or Not to Measure: Direct Oral Anticoagulant Laboratory Assay Monitoring in Clinical Practice by Tania Ahuja, Veronica Raco, Sharonlin Bhardwaj, David Green

“…Therapeutic drug monitoring with DOACs may help predict bleeding events in elderly patients, those with impaired renal function, and in the event of an emergent or urgent procedure. …”
Get full text

Organizational and legal measures to prevent psychosocial risks caused by the war in Ukraine by V. I. Teremetskyi, R. V. Kolodchyna

“…It is emphasized that mental health reforms should be non-intrusive and organic to reduce coercion and support mental health service users to make their own decisions about treatment. …”
Get full text

Folie à Deux in the Setting of COVID-19 Quarantine by Maxsaya Baez Nuñez, Ezequiel Rodriguez, Matthew DeLuca, Krishan Chirimunj, Monica Dhingra

“…We relay the case of a middle-aged male and his mother, an elderly female, who presented with folie à deux in the context of shared delusions of persecution and somatization during the COVID-19 quarantine period. …”
Get full text

An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…A decline in immune response, exhibited in the form of immunosenescence and inflammaging, is an age-associated disturbance of the immune system known to predispose the elderly to a greater susceptibility to infection and poor vaccine response. …”
Get full text

A scoping review on bio-aerosols in healthcare and the dental environment. by Charifa Zemouri, Hans de Soet, Wim Crielaard, Alexa Laheij

“…; and 3) What is the hazard posed by pathogenic micro-organisms transported via the aerosol route of transmission?…”
Get full text

Toward a new interdisciplinary model to understand Alzheimer’s disease: The interplay between neurobiology and socio-economic factors by Hyun Jee Han, Clive Shrubsole

“…Introduction: In recent years, there has been emerging evidence that air pollution is a chronic source of neuroinflammation, which contributes to Alzheimer’s Disease (AD) and other forms of dementia, which are an increasingly common and devastating illness affecting elderly populations. Aim of this paper is to develop a new, interdisciplinary and theoretical model based on neurobiology, sociology of medicine and eco-political science for a better understanding of the etiopathogenesis of Alzheimer’s disease and other forms of dementia. …”
Get full text

Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya by Bibianne Waiganjo, Gervason Moriasi, Jared Onyancha, Nelson Elias, Francis Muregi

“…It affects persons of all ages; however, pregnant mothers, young children, and the elderly suffer the most due to their dwindled immune state. …”
Get full text

Identification of novel clinical subtypes in patients with microscopic polyangiitis using cluster analysis: multicenter REVEAL cohort study by Ayana Okazaki, Shogo Matsuda, Takuya Kotani, Keisuke Fukui, Keisuke Fukui, Takaho Gon, Ryu Watanabe, Atsushi Manabe, Mikihito Shoji, Keiichiro Kadoba, Ryosuke Hiwa, Wataru Yamamoto, Motomu Hashimoto, Tohru Takeuchi

“…Cluster 2 comprised the elderly onset systemic inflammation group (N=75). …”
Get full text