Efficacy and safety of perioperative sintilimab plus platinum-based chemotherapy for potentially resectable stage IIIB non-small cell lung cancer (periSCOPE): an open-label, single... by Xiangyang Yu, Chujian Huang, Longde Du, Chunguang Wang, Yikun Yang, Xin Yu, Shengcheng Lin, Chenglin Yang, Hongbo Zhao, Songhua Cai, Zhe Wang, Lixu Wang, Xiaotong Guo, Baihua Zhang, Zhentao Yu, Jie He, Kai Ma

“…As of October 31, 2024, the median follow-up was 34.7 months. The estimated EFS and OS rates at 36 months in the intention-to-treat population were 42.8% and 70.1%, respectively, and the estimated DFS and OS rates at 36 months in the PP population were 52.5% and 70.4%, respectively. …”
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Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in People Living With HIV Attending Centre of Excellence in HIV Care at a Tertiary Level Teaching Hospital in North... by Ragini Ram, Anuradha Subramanian MD, MSc, FRCP, Rajeshwari K. MD, PhD, FRCPCH

“…Higher BMI (mean difference [MD] = 3.25, P  = .09), waist circumference (MD = 3.84, P  = .15), hip circumference (MD = 4.36, P  = .14), and older age (MD = 6.56, P  = .07) were observed to be associated with MASLD in our study, whereas the biochemical parameters and HIV-related factors were not seen to have any particular trend of association in our study. However, a higher median CD4 count was associated with MASLD as compared to the group without fatty changes on USG. …”
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Leer rápido no siempre es igual a comprender: Examinando la relación entre velocidad y comprensión/Reading Fast is not always the same as Understanding: Examining the Relationship... by Gabriela Silva-Maceda, Silvia Romero-Contreras

“…The objective of this study was to examine the relationship between reading speed and reading comprehension in a cross-sectional sample of Mexican children between 1st and 4th grades, in order to: a)identify the way that text reading speed and pseudoword reading speed are related to reading comprehension; b) identify whether these relationships differ between 1st cycle (1st and 2nd grades) and 2nd cycle (3rd and 4th grades). …”
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1-(5-ACETYL-3-METHYL-6-PHENYL-5H-[1,2,4]TRIAZOLO [3,4-b][1,3,4]THIADIAZIN-7-YL)-ETHANONE: DOSE-DEPENDENCE OF ANALGESIC EFFECT, LACK OF OPIOIDERGIC MECHANISM OF ACTION, EFFECT ON BE... by Andriy Koval, Sergiy Shtrygol

“…The average increase in the LP nociceptive response during its use per se was 306.3%, and during the previous blockade of opioid receptors with naloxone - 204.4%, that is, it decreased on average by a third, and the median of the final latent time decreased by 2 times with almost the same initial value. …”
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Decreased vitamin D increase the risk for subclinical hypothyroidism in individuals with T2DM: a cross-sectional study by Yaling Fang, Yaling Fang, Xin Wen, Hui You, Yueye Huang, Shen Qu, Xingchun Wang, Le Bu

“…Patients were categorized into lower and higher VD groups based on the median. Thyroid function was compared between groups and their association was analyzed.ResultsBody mass index (BMI), total cholesterol (TCH), triglyceride (TG), and free fatty acid (FFA) were significantly lower in the higher VD group compared to the lower VD group (all p < 0.05). …”
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Prognostic value of intraductal carcinoma subtypes and postoperative radiotherapy for localized prostate cancer by Fang Cao, Qing Li, Tianyu Xiong, Yingjie Zheng, Tian Zhang, Mulan Jin, Liming Song, Nianzeng Xing, Yinong Niu

“…Results A total of 139 patients were included in this study with a median follow-up of 61.5 months. K-M curves showed that patients with “IDC-P (+) RP only” had the worst prognosis; patients with IDC-P could have a survival benefit after receiving PORT; whereas patients with non-intraductal carcinoma had a better prognosis than the above patients with or without PORT. …”
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Análisis de habilidades y percepciones sobre mHealth en el manejo de pacientes crónicos por profesionales de atención primaria by Daniel Monasor Ortola, José Joaquín Mira Solves, Antonio Esteve Ríos

“…Results: A total of 181 professionals participated, showing high proficiency in managing mobile applications (median score of 8 out of 10; IQR = 2), with higher proficiency observed among younger professionals (P < .001). 56.35% had prescribed official or scientifically endorsed digital information. …”
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Conflict-related and sexual trauma in treatment-seeking Arabic-speaking men: a cross-sectional studyResearch in context by Max Vöhringer, Freya Specht, Christine Knaevelsrud, Birgit Wagner, Maria Böttche, Yuriy Nesterko

“…Of these, 2138 men indicated having experienced at least one traumatic event from a list of 23 types of events (man-made and non-man-made trauma) and were included in the study (age median: 25, age interquartile range: 10). 22% (n = 471) of participants were categorised into the STo group, 5.9% (n = 127) into the ST + CRT group, 18.6% (n = 397) into the CRTo group, and 53.5% into the Non-ST/CRT group (n = 1143). …”
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Association of T3/T4 ratio with inflammatory indicators and all-cause mortality in stroke survivors by Sheng Zhang, Zhongzhou Su, Xianqiang Wen

“…The mediation effect analysis was used to analyze whether the ratio of T3/T4 could mediate the survival time through inflammatory indicators.ResultsAccording to the inclusion and exclusion criteria, a total of 267 people were included in the study, with a mortality rate of 49.06% (131/267), an average survival time of 111.22 ± 3.19 months, and a median survival time of 130 ± 11.27 months. The Log-Rank test and K-M survival curve showed that there were statistical differences among the Q1, Q2, and Q3 groups of the T3/T4 ratio (x2 = 16.32, p&lt;0.001), and the lower the T3/T4 level, the shorter the survival time. …”
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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Patients’ information was collected using standard AMR surveillance tools, and either pus swabs or pus aspirate or necrotic tissues were collected and analyzed using standard microbiological procedures, WHONET and STATA software programs.Results: The median age (interquartile range) of patients was 34 (14– 54) years with males accounting for 54.4%. …”
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Guías impresas en 3D: ¿mejoran el control local y la supervivencia global en el tratamiento de los sarcomas pélvicos? Estudio de validación clínica by T. Fernández-Fernández, L. Mediavilla-Santos, M. Cuervo-Dehesa, E. Gómez-Larrén, R. Pérez-Mañanes, J. Calvo-Haro

“…Material and methods: A cohort study included 25 patients with primary pelvic or sacral sarcomas: 10 in the 3D group and 15 in the control group, with a median follow-up of 47 months. Demographic and clinical data, including tumor histology, stage, resection technique, associated reconstruction, adjuvant therapies, and complications, were evaluated. …”
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Carnívoros en el sudoeste de la provincia de Buenos Aires: ecología y conflictos con los ganaderos by N. CARUSO, E.M. LUENGOS VIDAL, M. LUCHERINI, M. GUERISOLI, S. MARTINEZ, E.B. CASANAVE

“…El zorro y el zorrino fueron las especies con una mayor adaptabilidad, mientras que el puma y el gato montés serían más sensibles a las modificaciones del ecosistema. …”
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Designing a model to improve the behavior of Iranian handicrafts e-commerce customers by increasing customer trust by mohsen seidi, Fataneh Alizadeh Meshkani, Ahmad Sardari, Abdullah Naami

“…Zolfaghar Dolabi (2023) investigated the factors affecting customer loyalty and electronic trust in electronic commerce in Tehran Infrastructure Company. The results of the research in the Tehran infrastructure company showed that the quality of the user interface has a positive and significant effect on customer satisfaction and trust. …”
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Explaining the model of value creation of tax income and gross domestic product based on tax system reforms by Bahram Ramazani, Mojtaba Malekichoobari, Sina Kheradyar

“…The statistical population of the research in the qualitative part includes 12 managers and assistants of the tax system, experts and consultants selected by non-probability sampling method with multiple strategies (intensity and snowball); and in the quantitative part it includes 265 people from those who were working in the administration of tax affairs of Tehran province, selected by random cluster sampling method. …”
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The Role of Different Emotional States of Customers on Food Preferences by Mahmood Ghanbari, Kambiz Heidarzadeh Hanzaee, Behnaz Khodayari, Maryam Khalili Araghi

“…The statistical population of the research in the qualitative part includes 26 people from the food consumers of restaurants and food courts in shopping centers of Tehran (Arg, Kurosh, Palladium, Sana, Iran Mall, etc.), and sampling was done in the targeted manner; and the quantitative part includes 448 persons who, like the qualitative part, were selected randomly available from the consumers of food. …”
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Comparison on the effect of different dressings on poor wound healing after surgery via posterior midline approach (不同敷料对后正中手术入路切口愈合不良的影响差异研究)... by ZHANG Tingting (张婷婷), ZHANG Hongyang (张宏扬), ZHU Ruifang (朱瑞芳)

“…Conclusion The utilization of silver alginate + hydrocolloid dressing outperformed traditional dressings in safeguarding against impaired wound healing following a posterior median surgical approach. This intervention not only shorten wound healing time but also reduced the frequency of dressing changes, thereby alleviating pain and promoting prompt wound recovery among pediatric patients. …”
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Redistribución espacial y migración interna de la población en Chile en los últimos 35 años (1965-2002): una síntesis de las hipótesis y la evidencia by Daniela González Ollino, Jorge Rodríguez Vignoli

“…El primero atañe a la concentración de la población chilena en el Área Metropolitana del Gran Santiago (amgs) y en la región político administrativa que la contiene (Región Metropolitana o rm); dos hipótesis en pugna se confrontan con los datos: la que sugiere la prevalencia del atractivo migratorio del amgs y la rm, como resultado de su capacidad para seguir liderando el dinamismo económico, y la que plantea un cambio de orientación de los flujos, tras lo cual quedarían el amgs y la rm con saldos negativos por la pérdida que tendrían en el intercambio con las regiones más dinámicas, que serían aquellas mejor ubicadas en la globalización productiva. …”
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Perbandingan Metode Penyelesaian Permasalahan Optimasi Lintas Domain dengan Pendekatan Hyper-Heuristic Menggunakan Algoritma Reinforcement-Late Acceptance by Anang Firdaus, Ahmad Muklason, Vicha Azthanty Supoyo

“…Secara lebih spesifik, RL-LA dapat meningkatkan peforma pencarian dalam menemukan solusi optimal pada 18 instance dari 30 instance atau sebesar 64%, dan jika dilihat dari nilai median dan minimum metode RL-LA lebih unggul 28% dari metode SR-LA.  …”
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Evaluation of Tumour Necrosis Factor Alpha, Interleukin-2 Soluble Receptor, Nitric Oxide Metabolites, and Lipids as Inflammatory Markers in Type 2 Diabetes Mellitus

“…Type 2 DM patients (<mml:math alttext="$n=39$"> <mml:mi>n</mml:mi> <mml:mo>=</mml:mo> <mml:mn>39</mml:mn> </mml:math>; age <mml:math alttext="$53.3pm 9.0$"> <mml:mn>53.3</mml:mn> <mml:mo>&#x00B1;</mml:mo> <mml:mn>9.0</mml:mn> </mml:math> years; median glycated haemoglobin <mml:math alttext="$A_{1c} < 8\%$"> <mml:msub> <mml:mtext>A</mml:mtext> <mml:mrow> <mml:mtext>1c</mml:mtext> </mml:mrow> </mml:msub> <mml:mo>&#x003C;</mml:mo> <mml:mn>8</mml:mn> <mml:mi>&#x0025;</mml:mi> </mml:math>) presented higher levels of TNF-<mml:math alttext="$alpha$"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, triglycerides (<mml:math alttext="$P < .01$"> <mml:mi>P</mml:mi> <mml:mo>&#x003C;</mml:mo> <mml:mn>.01</mml:mn> </mml:math>), NO<mml:math alttext="$^x$"> <mml:msup> <mml:mi/> <mml:mi>x</mml:mi> </mml:msup> </mml:math> and sIL-2R (<mml:math alttext="$P < .05$"> <mml:mi>P</mml:mi> <mml:mo>&#x003C;</mml:mo> <mml:mn>.05</mml:mn> </mml:math>) than control group (<mml:math alttext="$n=28$"> <mml:mi>n</mml:mi> <mml:mo>=</mml:mo> <mml:mn>28</mml:mn> </mml:math>; age <mml:math alttext="$39.7pm 14.1$"> <mml:mn>39.7</mml:mn> <mml:mo>&#x00B1;</mml:mo> <mml:mn>14.1</mml:mn> </mml:math> years). …”
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Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

“…Additionally, the linear or non-linear connection between BAR and ACM was ascertained with restricted cubic spline (RCS) approaches, supplemented by interaction and subgroup analyses.ResultsPrior to PSM, we incorporated 1,764 suitable subjects with a median BAR of 5.52 mg/g. This cohort was composed of 1,395 and 369 patients in the BAR &lt;10.42 and ≥10.42 groups, respectively. …”
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