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6821
Ethnic and racial discrimination in maternal health care in Mexico: a neglected challenge in the search for universal health coverage
Published 2025-01-01“…Our study included n = 72,873 (N = 23,245,468) Mexican women aged 12–54 with recent live births. …”
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6822
Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data
Published 2025-03-01“…The majority (68.9%) were diagnosed with intrahepatic or extrahepatic cholangiocarcinoma, and 80% had metastatic disease at the time of treatment. The pooled median OS in the GemCis group was 11.6 months (95% CI 11.3–12.2 months). …”
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6823
Validity, Agreement and Reliability of the ForceFrame Dynamometer in Patients with Anterior Cruciate Ligament Injury
Published 2024-09-01“… # Results Twenty-seven participants (10 females, 17 males) with a median age of 25 years (range 19-60) were included in this study. …”
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6824
Genetic variants associated with sepsis-associated acute kidney injury.
Published 2024-01-01“…Of these patients, 383 (11.4%) developed Stage 1, 2, or 3 AKI (primary outcome) and 181 (5.4%) developed Stage 2 or 3 AKI (sensitivity analysis). The median age was 61 years (interquartile range (IQR): 51,69), 42% were female, and the increase in SOFA score (between 48-hours before to 24-hours after the onset of suspected infection) was 2 (2-3). …”
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6825
Elevated Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict Incident Ischemic Cardiovascular Events in a Longitudinal and Prospective AMI Aging Study
Published 2025-02-01“…Initially, participants were stratified into three groups according to the tertile levels of FABP4, followed by further categorization based on various lipid profiles and specific inflammatory markers.Results: On follow-up (median 751 days, maximum 1506 days), a total of 158 ischemic events were recorded. 1) In multivariable models meticulously adjusted for age, gender, traditional coronary heart disease factors, Killip classification, and discharge medications, the association of elevated levels of FABP4 (Tertile 3 HR 1.618 [1.061 to 2.468], p=0.026), augmented concentrations of PTX3 (Tertile 3 HR 1.811 [1.211 to 2.710], p=0.004), or LL-37 (Tertile 3 HR 0.651 [0.433 to 0.981], p=0.040) with ischemic risk was markedly intensified. 2) Multivariate HRs associated with 1 standard deviation (SD) (mg/dL) increase in the FABP4 parameters were as follows in different subgroups. 1-SD difference in FABP4 was associated with a 23%, 23%, 21 and 29% increase in ischemic events over after fully adjusted the confounding risk factors among male, patients with hyperlipidemia, hypertension and diabetes respectively. 3) The Kaplan-Meier curve demonstrated significant differences between the tertiles of FABP4 index levels among all enrolled participants (p=0.0180).Conclusion: This study reinforces the utility of FABP4 for enhancing risk stratification specifically among older patients diagnosed with ST-elevation myocardial infarction.Keywords: FABP4, lipid profile, PTX3, LL-37, ischemic vascular events…”
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6826
Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) studyRe...
Published 2025-02-01“…Severe adverse events were rare (0.8% of participants after the first and 1.1% after the second vaccination), and none were life-threatening or fatal. Among PLWH, the median CD4 count was 635 cells/μl and 18.5% had HIV viraemia. …”
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6827
Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke
Published 2022-10-01“…Surface electromyography (sEMG) was used to measure the median frequency (MF) and integrated electromyography (iEMG) of the patients' bilateral erector spinae and multifissure muscles.ResultsBefore treatment, there was no statistically significant difference in PASS, BBS, FMA-LE, MBI scores, or bilateral erector spinae and multifidus MF and iEMG values between the two groups (<italic>P</italic>>0.05). …”
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6828
Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study
Published 2025-01-01“…Analysis showed general satisfaction with the app’s workout videos, which were used in 585 sessions with a median duration of 14 (IQR 0-34) minutes per day. …”
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6829
Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study
Published 2025-02-01“…Subgroup analyses by sex, age, smoking status, race, body mass index, level of education, poverty-to-income ratio, respiratory symptoms, and comorbidities were performed in participants with the different spirometry classifications.Results: Overall, 24,691 participants were included, with a median follow-up time of 25.7 years. Of these, 19,969 had normal spirometry and 1,452 had PRISm. …”
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6830
Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis
Published 2025-03-01“…Analytical Approach: Cox proportional regression adjusting for demographic, lifestyle, and clinical variables was performed to estimate associations between different eGFR measures and risk of incident stroke and dementia. Results: During a median follow-up period of 17 years, 349 (5.3%) participants experienced an incident stroke event, and 574 (8.6%) participants experienced incident dementia. …”
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6831
Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?
Published 2024-12-01“…Furthermore, the predictive value of haematological parameters was determined on the overall response to adjuvant radiotherapy and for the ESGO/ESTRO/ESP intermediate-risk group solely receiving radiotherapy.Results A total of 894 patients were included with a median follow-up of 4.5 years. Anaemia was present in 103 (11.5%), thrombocytosis in 79 (8.8%) and leucocytosis in 114 (12.7%) patients. …”
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6832
Presenting a Prediction Model for CEO Compensation Sensitivity using Meta-heuristic Algorithms (Genetics and Particle Swarm)
Published 2024-09-01“…Methods The statistical population of this research comprises all companies listed on the Tehran Stock Exchange from 1390 to 1400. To select the sample, a systematic elimination method was employed, resulting in a sample of 110 companies. …”
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6833
Urbanizaciones cerradas en Mar del Plata: ordenamiento territorial y construcción social del espacio
Published 2019-08-01“…Así, los proyectos de urbanización cerrada -a escala local- serían el resultado de la interacción entre la acción de los organismos estatales, el mercado inmobiliario y los agentes privados que definen su crecimiento y expansión en el sector sur de la ciudad. …”
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6834
Six MicroRNA Prognostic Models for Overall Survival of Lung Adenocarcinoma
Published 2022-01-01“…Finally, the prognostic model was scored by risk, divided into high- and low-risk groups by median, and the differences in the immersion level of 21 immune cells in the high- and low-risk groups were assessed. …”
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6835
Association of Differing Qatari Genotypes with Vitamin D Metabolites
Published 2020-01-01“…The distribution was as follows: 164 (41.2%) genotyped Q1, 149 (37.4%) genotyped Q2, 31 (7.8%) genotyped Q3, and 54 (13.6%) genotyped “admixed.” Median levels of 25(OH)D and 3epi-25(OH)D did not differ across Q1, Q2, Q3, and “admixed” genotypes, respectively. 1,25(OH)2D levels were lower (p<0.04) between Q2 and the admixed groups, and 24,25(OH)2D levels were lower (p<0.05) between Q1 and the admixed groups. …”
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6836
Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction
Published 2025-01-01“…Multivariate COX regression assessed mortality associations.Results: With a median follow-up of 33 months, overall mortality was 21.7% for heart rates ≤ 77 bpm and 30.4% for > 77 bpm. …”
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6837
Identification of multiple complications as independent risk factors associated with 1-, 3-, and 5-year mortality in hepatitis B-associated cirrhosis patients
Published 2025-02-01“…The maximum follow-up period was 10.75 years, with a median of 5.75 years. Eight machine learning techniques were employed to construct predictive models, including C5.0, linear discriminant analysis (LDA), least absolute shrinkage and selection operator (LASSO), k-nearest neighbour (KNN), gradient boosting decision tree (GBDT), support vector machine (SVM), generalised linear model (GLM) and naive Bayes (NB), utilising variables such as medical history, demographics, clinical signs, and laboratory test results. …”
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6838
Oxidative balance score and its association with chronic inflammatory airway diseases and mortality: a population-based study
Published 2025-01-01“…We found that 20.26% of the participants were suffered from CIAD, followed by asthma (15.41%), chronic bronchitis (6.10%) and COPD (3.80%), respectively. The median OBS levels were 20.98 with a standard deviation of 0.17. …”
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6839
A simple staging system using biomarkers for wild‐type transthyretin amyloid cardiomyopathy in Japan
Published 2022-06-01“…Kaplan–Meier analyses revealed significant differences in all‐cause death and rehospitalization for heart failure (log rank test; P < 0.001), and after adjusting for sex and age, the hazard ratio of all‐cause death was 6.96 (95% Cl 2.88–16.83, P < 0.001) and that for rehospitalization for heart failure was 4.27 (95% Cl 2.26–8.07, P < 0.001) in the high‐risk group, compared with those in the low‐risk group. The median survival period was 32.0 months in the high‐risk group. …”
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6840
Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study
Published 2024-12-01“…During 781,125 person-years of follow-up (length of follow-up: median 6.07, IQR 3.07‐7.09 years), 290 individuals were diagnosed with liver cancer. …”
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