An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study by Guanghao Liu, Shixiang Zheng, Jun He, Zi-Mei Zhang, Ruoqiong Wu, Yingying Yu, Hao Fu, Li Han, Haibo Zhu, Yichang Xu, Huaguo Shao, Haidan Yan, Ting Chen, Xiaopei Shen

“…ResultsUsing only vital signs and rapid arterial blood gas test features according to feature importance, we constructed the Septic Shock Risk Predictor (SORP), with an area under the curve (AUC) of 0.9458 in the test set, which is only slightly lower than that of the optimal multi-feature complex model (0.9651). A median forewarning time of 13 hours was calculated for SS patients. 4 distinct risk groups (high, medium, low, and ultralow) were identified by the SORP 6 hours before onset, and the incidence rates of SS in the 4 risk groups in the postonset interval were 88.6% (433/489), 34.5% (262/760), 2.5% (67/2707), and 0.3% (4/1301), respectively. …”
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Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality by Fernando García-García, Dae-Jin Lee, Mónica Nieves-Ermecheo, Olaia Bronte, Pedro Pablo España, José María Quintana, Rosario Menéndez, Antoni Torres, Luis Alberto Ruiz Iturriaga, Isabel Urrutia, COVID-19 & Air Pollution Working Group

“…Our clustering algorithm identified k=3 distinct phenotypes and 18 strongly informative variables: Phenotype A (788 cases [50.9% prevalence] – age $$\sim$$ ∼ 57, Charlson comorbidity $$\sim$$ ∼ 1, pneumonia CURB-65 score $$\sim$$ ∼ 0 to 1, respiratory rate at admission $$\sim$$ ∼ 18 min-1, FiO2 $$\sim$$ ∼ 21%, C-reactive protein CRP $$\sim$$ ∼ 49.5 mg/dL [median within cluster]); phenotype B (620 cases [40.0%] – age $$\sim$$ ∼ 75, Charlson $$\sim$$ ∼ 5, CURB-65 $$\sim$$ ∼ 1 to 2, respiration $$\sim$$ ∼ 20 min-1, FiO2 $$\sim$$ ∼ 21%, CRP $$\sim$$ ∼ 101.5 mg/dL); and phenotype C (140 cases [9.0%] – age $$\sim$$ ∼ 71, Charlson $$\sim$$ ∼ 4, CURB-65 $$\sim$$ ∼ 0 to 2, respiration $$\sim$$ ∼ 30 min-1, FiO2 $$\sim$$ ∼ 38%, CRP $$\sim$$ ∼ 152.3 mg/dL). …”
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De organografía, organología y etnolaudería como propuesta para el estudio de los instrumentos musicales tradicionales by Víctor Hernández Vaca

“…Abstract In a review of the classical literature on traditional Mexican musical instruments, several results come to light: scholars, including myself, have spoken indistinctively of organography and organology as the conceptual and methodological frameworks for the study of the traditional musical instrument. …”
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LAS TRANSFORMACIONES TERRITORIALES FRONTERIZAS SEGÚN LA CONCEPCIÓN IDEOLOGICA DE FRONTERA (1991-1995) by Alicia Laurín

“…Los recortes territoriales denominados área de frontera y región fronteriza, serían la resultante espacial de la concepción de frontera cerrada en el primer caso y la de frontera abierta en el segundo. …”
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Performance Evaluation of Large Language Models in Cervical Cancer Management Based on a Standardized Questionnaire: Comparative Study by Warisijiang Kuerbanjiang, Shengzhe Peng, Yiershatijiang Jiamaliding, Yuexiong Yi

“…Interpretability analysis showed that prompts improved alignment with human annotations for proprietary models (median intersection over union 0.43), while medical-specialized models exhibited limited improvement. …”
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Second-line treatment patterns and outcomes in advanced HCC after progression on atezolizumab/bevacizumab by Meng Wu, Claudia A.M. Fulgenzi, Antonio D’Alessio, Alessio Cortellini, Ciro Celsa, Giulia F. Manfredi, Bernardo Stefanini, Y. Linda Wu, Yi-Hsiang Huang, Anwaar Saeed, Angelo Pirozzi, Tiziana Pressiani, Lorenza Rimassa, Martin Schoenlein, Kornelius Schulze, Johann von Felden, Yehia Mohamed, Ahmed O. Kaseb, Arndt Vogel, Natascha Roehlen, Marianna Silletta, Naoshi Nishida, Masatoshi Kudo, Caterina Vivaldi, Lorenz Balcar, Bernhard Scheiner, Matthias Pinter, Amit G. Singal, Joshua Glover, Susanna Ulahannan, Fredrich Foerster, Arndt Weinmann, Peter R. Galle, Neehar D. Parikh, Wei-Fan Hsu, Alessandro Parisi, Hong Jae Chon, David J. Pinato, Celina Ang

“…In the second line, 155 patients were treated with tyrosine kinase inhibitors (TKIs), 45 with immune checkpoint inhibitor (IO)-based regimens, and 3 had missing data. Median PPS of the whole cohort (mPPS) was 6.0 months (95% CI 5.2-7.2). …”
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Distribution and Related Influencing Factors of AMH Level in Family-Planning Women of Childbearing Age: A Cross-Sectional Study from Beijing, China by Song J, Gao S, Zhao L, Tong X

“…Two different factors influencing AMH level were analyzed using a logistics model.Results: The AMH level decreased with age, with a median AMH of < 2.0 ng/mL for subjects aged ≥ 36 years. …”
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Effect analysis of radiofrequency catheter ablation in the treatment of 7 children with atrial tachycardia-induced cardiomyopathy by Min Zhang, Xiaoxiao Cao, Suqiong Ji, Mohammadreza Kosari, Yong Zhang

“…Results The age range was 3.6 to 13 years and the median age was 11.2 years. The weight range was from 15 to 92 kg, the average weight was 34 kg. …”
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Effect of Dietary Magnesium on the Association Between Serum Uric Acid and Female Infertility by Xin X, Zhang Q, Xu J, Huang J

“…Dietary magnesium was divided into two groups based on the median number of participants (low magnesium intake, < 243 mg/day; high magnesium intake, ≥ 243 mg/day).Results: A total of 3185 female participants were included in the final analysis, 10.58% of whom were infertile. …”
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Proportion, quality of life and factors associated with perinatal urinary incontinence among pregnant women attending at Muhimbili national hospital by Geofrey P. Chiloleti, Fransia Arda Mushi, Aboud Muhsin, Ally Mwanga

“…The statistical analysis of the data was done in the SPSS version 20, whereby descriptive statistics and categorical data were described by frequency tables, graphs, and percentages, and numerical variables by mean, median, and standard deviation. Bivariate logistic regression was used to obtain variables that were associated with PUI. …”
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Role of 18F-PSMA-1007 PET/CT-derived quantitative volumetric tumor parameters in cytoreductive radical prostatectomy selection for patients with low-volume metastatic hormone-sensi... by Junjie Fan, Ke Xu, Zhangdong Jiang, Chaosheng Gan, Hao Song, Guoqiang Gao, Guojing Wang, Qiyuan Kang, Liang Luo, Zhuonan Wang, Dalin He, XiaoYi Duan, Kaijie Wu

“…Results Among 122 patients, 37 (30.32%) underwent systemic therapy plus cRP. The median and optimal cutoff values of the whole-body PSMA-TV were 71.68 cm3 (41.28–157.41 cm3) and 78.57 cm3, respectively. …”
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Association of dietary quality and mortality in the non-alcoholic fatty liver disease and advanced fibrosis populations: NHANES 2005–2018 by Xingyong Huang, Xiaoyue Zhang, Xuanyu Hao, Tingting Wang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wenyu Wan, Wenyu Wan, Wenyu Wan, Kai Zhang

“…Weighted Cox proportional hazard regression models along with restricted cubic splines and subgroup analyses were employed in this study.ResultsThe analysis encompassed 3,634 NAFLD patients. After a median follow-up of 89 months, it was found that higher scores on the aMED (HR 0.814, 95% CI 0.681–0.972), HEI-2020 (HR 0.984, 95% CI 0.972–0.997), DASH (HR 0.930, 95% CI 0.883–0.979), and AHEI (HR 0.980, 95% CI 0.966–0.995) were associated with lower mortality risks, while DII scores (HR 1.280, 95% CI 1.098–1.493) indicated an increased risk of mortality. …”
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Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shuntResearch in context by Binlin Da, Huan Chen, Wei Wu, Wuhua Guo, Anru Zhou, Qin Yin, Jun Gao, Junhui Chen, Jiangqiang Xiao, Lei Wang, Ming Zhang, Yuzheng Zhuge, Feng Zhang

“…Findings: A total of 400 patients in our cohort were included (median age and interquartile range, 59 (50, 66); 240 men). …”
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Risk of hepatocellular carcinoma in Asian patients with primary biliary cholangitis: A nationwide and hospital cohort study by Jihye Lim, Ye-Jee Kim, Sehee Kim, Jonggi Choi

“…Results: In total, 105 patients with PBC developed HCC over the median follow-up period of 5.42 years, yielding an incidence rate of 3.7/1,000 person-years (PYs), which was significantly higher than that in the controls (0.5/1,000 PYs; adjusted hazard ratio: 9.07; 95% CI: 6.71–12.27). …”
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The triglyceride-glucose index trajectories are associated with cardiovascular diseases in people living with HIV: evidence from a prospective cohort study in China, 2005–2022 by Yinsong Luo, Liqin Sun, Yun He, Fang Zhao, Duo Shan, Fan Bu, Lingyun Ge, Xiaorui Li, Yiyao Hu, Xi Xiao, Hongzhou Lu, Jiaye Liu

“…Nonlinear relationships were investigated using a restricted cubic spline plot. Results During a median follow-up of 70 months, 214 PLWH developed CVD. …”
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Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy by Bambang Pujo Semedi, Nadya Noor Ramadhania, Betty Agustina Tambunan, Siprianus Ugroseno Yudho Bintoro, Soedarsono Soedarsono, Cita Rosita Sigit Prakoeswa

“…Overall mortality rate in our COVID-19 ICU was 55.3%, with a median overall length of stay of 8 (4–11) days. Less patients that received convalescent plasma presented with the need for mechanical ventilation on ICU admission p<0.001, but with comparable PaO2 to FiO2 (P/F) ratio p=0.95. …”
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Glycemic Management of Patients with Hospital Hyperglycemia: A Retrospective Cohort Study on Adults Admitted in the Non-ICU Wards by Zheng R, Zeng X, Shen R, Wang Y, Liu J, Zhang M

“…In the ≥ 80 years group, the median BG was 9.4 mmol/L, significantly higher than in other age groups (p< 0.001). …”
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Machine learning derivation of two cardiac arrest subphenotypes with distinct responses to treatment by Weidong Zhang, Chenxi Wu, Peifeng Ni, Sheng Zhang, Hongwei Zhang, Ying Zhu, Wei Hu, Mengyuan Diao

“…Results After applying exclusion criteria, 719 CA patients were included in the study, with a median age of 67.22 years (IQR: 55.50-79.34), of whom 63.28% were male. …”
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Accelerometer-measured physical activity, sedentary behavior, and incidence of macrovascular and microvascular events in individuals with type 2 diabetes mellitus and prediabetes by Yannis Yan Liang, Yu He, Piao Huang, Hongliang Feng, Haiteng Li, Sizhi Ai, Jing Du, Huachen Xue, Yaping Liu, Jun Zhang, Lu Qi, Jihui Zhang

“…The events were ascertained using the International Classification of Diseases-10 (ICD-10) codes on the hospital or death records. Results: During a median follow-up of 6.8 years, 1680 cases were documented, including 969 macrovascular events, 839 microvascular events, and 284 incidents of HF. …”
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Emerging Implications of Serum Resolvin D2 as a Biochemical Marker for Severity Assessment and Prognosis Prediction Following Moderate-Severe Traumatic Brain Injury: A Prospective... by Zong H, Zong Y, Li J, Zhao S, Wu W, Chen R, Zhao G, Li Z

“…Sequential univariate and multivariate analyses were used to determine the correlative factors of changeable serum RvD2 levels and the predictors of adverse prognosis.Results: Patients displayed a marked decline in serum RvD2 levels compared to controls (median, 95.2 versus 252.8 pg/mL; P< 0.001). Serum RvD2 levels were independently correlated with GCS scores (beta, 8.989; 95% confidence interval (CI), 3.678– 14.280; P=0.001) and Rotterdam scores (beta, − 14.676; 95% CI, − 25.885--3.468; P=0.011), and were independently associated with continuous GOS scores (beta, 0.004; 95% CI, 0.002– 0.007; P=0.003), ordinal GOS scores (odds ratio, 1.008; 95% CI, 1.002– 1.015; P=0.015), and poor prognosis (odds ratio, 0.991; 95% CI, 0.983– 0.999; P=0.037) at the six-month mark. …”
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