Construction and validation of a prognostic model for NK/T-cell lymphoma based on random survival forest algorithm by HUANG Zhen, HUANG Zhen, WU Yazhou

“…Then the patients were divided into high- and low-risk groups based on the median risk score, and survival curve was plotted for comparison. …”
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Incident Heart Failure in Atherosclerotic Renal Artery Stenosis: A Post Hoc Analysis of the CORAL Trial by Rajesh Gupta, Michelle M. Estrella, Rebecca Scherzer, Pamela S. Brewster, Lance D. Dworkin, Hanh T. Nguyen, Yanmei Xie, Joachim H. Ix, Michael G. Shlipak, Timothy P. Murphy, Donald E. Cutlip, Eldrin F. Lewis, Christopher J. Cooper

“…Results: This analysis included 808 participants enrolled in the CORAL trial without evidence of baseline HF. During a median follow-up of 4.8 years, 54 participants (6.7%) developed incident HF. …”
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Implementation of the Lupus Low Disease Activity State in Pediatric Rheumatology Care: The Role of the Visual Analog Scale by Ekemini A. Ogbu, Anna Carmela P. Sagcal‐Gironella, B. Anne Eberhard, Jennifer M. Huggins, Marisa S. Klein‐Gitelman, Karen Onel, Chen Chen, Bin Huang, Hermine I. Brunner

“…Results In 600 visits, the median (range) scores of PhGA0–10, PhGA0–3, SLEDAI‐2k, SELENA‐SLEDAI, and BILAG were 2 (0–10), 1(0–3), 4 (0–28), 4 (0–32), and 2 (0–28), respectively. …”
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Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan by Chiara Trevisan, Amber Hadermann, Stephen Raimon Jada, Raphael A. Abong, Yak Yak Bol, Joseph N. Siewe Fodjo, Katja Polman, Robert Colebunders

“…A total of 317 women aged between 14 and 44 years participated in the study [median age: 23 years (IQR: 19–29)]. Of 290 women who were tested, 179 (61.7%) were Ov16 RDT positive (SD Bioline). …”
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Resuscitative endovascular balloon occlusion of the aorta in trauma management: a comprehensive study of clinical indications and challenges by Tongporn Wannatoop, Peerayuht Phuangphung, Tanut Sornmanapong

“…Absolute REBOA contraindications were assessed, particularly for aortic and cardiac injuries, with or without cardiac tamponade.Results Predominantly male, the cohort largely consisted of motorcycle accident victims. The median Injury Severity Score was 41 (range 1–75). …”
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Venous thromboembolism incidence and risk factors associated with immune checkpoint inhibitors among patients with advanced non-small cell lung cancer by Chi Nguyen, Alok A Khorana, John Barron, Jennell Palaia, Lisa Rosenblatt, Radhika Pisupati, Ning Huang, Kerrin Gallagher, T Christopher Bond

“…Cox proportional hazards models were used to investigate the factors associated with VTE risk.Results Among 2299 eligible patients (ICI-based, n=605; chemo-based, n=1092; ICI+chemo, n=602) with a median follow-up of 9.1 months, the VTE incidence rates (95% CI) per 100 person-years were 17.8 (95% CI 16.0 to 19.5) overall, 13.5 (95% CI 10.6 to 16.5) for ICI-based, 18.0 (95% CI 15.5 to 20.5) for chemo-based, and 22.4 (95% CI 20.2 to 24.5) for ICI+chemo. …”
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Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-we... by Xingrui Wang, Zhenhui Xie, Xiaoqing Wang, Yang Song, Shiteng Suo, Yan Ren, Wentao Hu, Yi Zhu, Mengqiu Cao, Yan Zhou

“…In IDH wild-type group, pVol of Habitat 2 was identified as a significant risk factor for PFS (high- vs. low-pVol subgroup, hazard ratio = 2.204, 95% CI: 1.061–4.580, P = 0.034), with a value below 0.26 indicating a 5-month median survival benefit. Conclusions Habitat imaging employing DCE-MRI and DWI may facilitate the characterization of ITH in adult-type diffuse gliomas and serve as a valuable adjunct in the preoperative prediction of IDH genotypes and prognosis. …”
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Mirvetuximab Soravtansine in solid tumors: A systematic review and meta-analysis. by Shamsnur Rehim, Shuang Yuan, Hongjing Wang

“…The primary end-point was median progression-free survival (mPFS). The secondary endpoints were the Objective response rate (ORR) and adverse effects (AEs). …”
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E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department by V. Yuvaraj, Sachin Sujir Nayak, S. Vimal Krishnan

“…RESULTS: A total of 250 patients with a median age of 53 years (42.25–63.00) were part of the study. …”
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Automated Quantification of Retinopathy of Prematurity Stage via Ultrawidefield OCT by Spencer S. Burt, BA, Aaron S. Coyner, PhD, Elizabeth V. Roti, BS, Yakub Bayhaqi, PhD, John Jackson, MD, Mani K. Woodward, MS, Shuibin Ni, PhD, Susan R. Ostmo, MS, Guangru Liang, BS, Yali Jia, PhD, David Huang, MD, Michael F. Chiang, MD, Benjamin K. Young, MD, Yifan Jian, PhD, John Peter Campbell, MD

“…Using the U-Net, ANVTV was associated with higher disease stage both cross sectionally and longitudinally. Median ANVTV significantly increased as ROP stage worsened from 1 (0, [interquartile range: 0–0] kilovoxels) to 2 (170.1 [interquartile range: 104.2–183.6] kilovoxels) to 3 (421.4 [interquartile range: 312.3–1110.8] kilovoxels; P < 0.001). …”
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Novel pyroptosis-immune-related lncRNA signature exhibits a distinct immune cell infiltration landscape in breast cancer by Dedi Kong, Dedi Kong, Hongju Cheng, Meihong Wang

“…Stepwise Cox regression was used to refine these signatures and to select the optimal lncRNA signature. The median risk score of the training subset was applied as a threshold to divide patients into high-risk (HR) and low-risk (LR) groups. …”
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Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 Patients by Armen Oganesyan, Ruslan Menzulin, Yury Surovoy, Andrei Nikiforchin, Kirill Zykov

“…Of 233 patients, 220 (median age: 65 years, 38% female) were included: 83 patients received dexamethasone and 137 received usual care. …”
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Prevalence of HIV infection and uptake of HIV/AIDs services among fishermen on the shores of Lake Victoria in Kagera region, Northwestern Tanzania. by Patrick Mwanahapa, Mtoro J Mtoro, Dina Gerald, Pius Horumpende, Salaam Mujeeb

“…<h4>Results</h4>A total of 774 fishermen with a median age of 31 years (interquartile range: 25-38 years) were recruited. …”
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COVID-19 on patients with immune-mediated rheumatic disease: a comparative study of disease activity, fatigue, and psychological distress over six months by Claudia Marques, Marcelo M. Pinheiro, Jennifer Lopes, Sandra Lúcia Euzébio Ribeiro, Mary Vânia Marinho de Castro, Lilian David de Azevedo Valadares, Aline Ranzolin, Nicole Pamplona Bueno de Andrade, Rafaela Cavalheiro do Espírito Santo, Nafice Costa Araújo, Cintya Martins Vieira, Valéria Valim, Flavia Patricia Sena Teixeira Santos, Laurindo Ferreira da Rocha, Adriana Maria Kakehasi, Ana Paula Monteiro Gomides Reis, Edgard Torres dos Reis-Neto, Gecilmara Salviato Pileggi, Gilda Aparecida Ferreira, Licia Maria Henrique da Mota, Odirlei Monticielo, Ricardo Machado Xavier

“…Results A total of 601 patients were evaluated—321 patients (IMRD COVID-19 + patients) and 280 controls (IMRD COVID-19- patients)—who were predominantly female with similar median ages. Disease activity assessment over a 6-month follow-up showed no significant difference between cases and controls. …”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016&ndash;... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Cuixin Qiang,1,&ast; Xiaoxuan Liu,1,&ast; Pu Qin,1 Hainan Wen,2 Zhirong Li,1 Jing Yang,1 Yanan Niu,1 Weigang Wang,1 Zirou Ouyang,1 Min Zhao,1 Jiayiren Li,1 Yulian Zhang,1 Jianhong Zhao1 1The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianhong Zhao, The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China, Tel +86 0311 66002711, Email zhaojh_2002@hebmu.edu.cnPurpose: To analyze the clinical distribution and antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) isolated from blood specimens in 75 hospitals in Hebei Province from 2016 to 2021 to aid in the rational selection of antimicrobial drugs.Patients and Methods: WHONET 5.6 and SPSS 24.0 were used to retrospectively analyze clinical distribution characteristics and variations in drug-resistance.Results: Between 2016 and 2021, 2208 P. aeruginosa strains were detected in blood specimens from Hebei Province. The median age of the patients with isolated P. aeruginosa was 63 years, with a male-to-female ratio of 2.1:1. …”
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Dispersion modelling of particulate matter concentrations of sand product plants in a mineral complex by Y. Zehtab Yazdi, N. Mansouri, F. Atabi, H. Aghamohammadi

“…This study was conducted to estimate dust concentrations released from these plants in a mineral complex in the southwest of Tehran.METHODS: Initially, the amount of silt and moisture content of the samples taken from these plants were determined according to the American Society for Testing and Materials C136 and D2216 methods, respectively. …”
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Impact of diabetes on clinical outcome of patients with heart failure undergoing ICD and CRT procedures: results from the German Device Registry by Elif Kaya, Jochen Senges, Matthias Hochadel, Lars Eckardt, Dietrich Andresen, Hüseyin Ince, Stefan G. Spitzer, Thomas Kleemann, Sebastian S.K. Maier, Werner Jung, Christoph Stellbrink, Tienush Rassaf, Reza Wakili

“…Subgroup analysis were performed for ICD and CRT implantations. Median follow‐up was 15.7 (12.9; 20.0) and 16.2 (12.8; 21.2) months in DM and non‐DM patients. …”
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Association Between Liver Fibrosis and Risk of Incident Stroke and Mortality: A Large Prospective Cohort Study by Zijie Wang, Zhitao Gong, Jianshang Wen, Shanyu Zhang, Xiao Hu, Wenliang Guo, Yanghua Tian, Qi Li

“…Results Among 379 953 participants (mean age, 56.2 [SD, 8.1] years; 44.6% men), 7396 (1.9%) had a Fibrosis‐4 index >2.67 at baseline. During a median follow‐up of 12.75 (interquartile range, 12.03–13.48) years, 7143 (1.9%) incident stroke cases were documented. …”
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Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing by Roldan Munoz S, Mol PGM, de Vries F, van Dijk PR, Hillege H, Postmus D, de Vries ST

“…Thematic analysis was conducted.Results: Fifteen patients participated (median age 64 years, nine women, and most had T2D > 10 years). …”
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Molecular testing stratifies the risk of structural recurrence in high risk differentiated thyroid cancer: a retrospective cohort study by Jie Liu, Wensi Gao, Xiong Zheng, Shuping Wu, Yi Shi, Feng Wang, Yu Wu

“…Patients harboring mutations in the TERT promoter, TP53, or PIK3CA genes were categorized as the high molecular risk group, while all others were assigned to the non-high molecular risk group.ResultsAmong the 108 cases, 32 (29.6%) fell into the high molecular risk group, characterized by a significantly older mean age (57.8 vs. 42.6 years, p &lt; 0.001), larger tumor size (3.1 cm vs. 2.0 cm, p = 0.003), a higher incidence of aggressive pathological subtypes (43.8% vs. 7.9%, p &lt; 0.001), and an increased occurrence of distant metastasis (34.4% vs. 7.9%, p = 0.001). Over a median follow-up period of 32.5 months, this high-risk group demonstrated an elevated risk of local recurrence (32.1% vs. 9.5%, HR: 3.18, 95% CI: 1.15-8.78) and metachronous distant metastasis (38.1% vs. 2.9%, HR: 12.54, 95% CI: 2.60-60.41). …”
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