A new phase of China-ASEAN health cooperation: the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies by Jie Qiao, Siyan Zhan, Minghui Ren, Haijun Wang, Yangmu Huang, Zhenyu Zhang, Yanan Luo, Hui Yin, Zhongwei Jia, Wei Huang, Hong Zhou, Jue Liu, Xiaoyun Liu, Qiudan Sun, Xiaojia Li, Jing Bai, Fangjing Liu, Yihong Liu, Yinzi Jin, Ming Xu, on behalf of China-ASEAN Science and Technology Cooperation Center for Public Health

“…Abstract Utilizing innovative methods to advance the research and development (R&D) of health products and enhance their accessibility has become crucial to achieving universal health coverage, addressing public health emergencies, and promoting population health and wellbeing. …”
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Quality assessment of spent laying hens and analysis of influencing factors by Runzhe Wang, Jiahui Lai, Guiyun Xu, Chuanwei Zheng, Zhiqiong Mao, Jiangxia Zheng

“…The sale of spent laying hens has become a significant revenue stream within the poultry industry. …”
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Frictional heat-assisted performance enhancement in dynamic Schottky contact of Al/Ag2Se-based tribovoltaic nanogenerator by Supakarn Worathat, Utchawadee Pharino, Phakkhananan Pakawanit, Arunothai Rattanachata, Rangson Muanghlua, Sugato Hajra, Hoe Joon Kim, Saichon Sriphan, Naratip Vittayakorn

“…Demonstrating the synergy between tribovoltaic and thermoelectric effects becomes achievable through the excellent thermoelectric property of Ag2Se. …”
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Targeting KRAS G12C and G12S mutations in lung cancer: In silico drug repurposing and antiproliferative assessment on A549 cells by Mansour S. Alturki, Nada Tawfeeq, Amal Alissa, Zahra Ahbail, Mohamed S. Gomaa, Abdulaziz H. Al Khzem, Thankhoe A. Rants'o, Mohammad J. Akbar, Waleed S. Alharbi, Bayan Y. Alshehri, Amjad N. Alotaibi, Fahad A. Almughem, Abdullah A. Alshehri

“…Despite the approval of two inhibitors for the KRAS G12C mutation (sotorasib and adagrasib), the necessity persists due to the emergence of resistance to these inhibitors, which has become a substantial concern. This work involved the repurposing of FDA-approved drugs through in silico methods to identify compounds capable of covalently binding to KRAS G12C (PDB entry: 6OIM) and G12S (PDB entry: 7TLG). …”
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Engineered GM-CSF polarizes protumorigenic tumor-associated macrophages to an antitumorigenic phenotype and potently synergizes with IL-12 immunotherapy by Yue Wang, Kevin Chang, Aslan Mansurov, Jun Ishihara, Seounghun Kang, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Brendan T K Berg, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Melody A Swartz, Jeffrey A Hubbell

“…Background The use of immune checkpoint inhibitors (CPIs) has become a dominant regimen in modern cancer therapy, however immune resistance induced by tumor-associated macrophages (TAMs) with immune suppressive and evasion properties limits responses. …”
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Selçuklu Hanedanlığında Evlilikler ve Evlilik Yaşları Üzerine Bir Değerlendirme by Sefer Solmaz, Mehmet Ali Kapar

“…Bu yorum ve değerlendirmelerde anakronik bir yanlış içerisine girilerek günümüz normları üzerinden geçmiş yargılanmaya çalışılmaktadır. Bu nedenle çalışmada dönem kaynaklarındaki bilgiler titizlikle incelenip kıyaslamalar da yapılarak bir sonuca ulaşılmaya çalışılmış ve Orta Çağ dünyasının genelinde olduğu gibi Selçuklularda da evliliklerin çok erken yaşlarda gerçekleştirildiği ortaya konulmuştur. …”
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Can We Improve Confusion, Uremia, Respiratory Rate, Blood Pressure, Age >65 with Lactate and Procalcitonin to Predict Mortality in Pneumonia? by Ahmet Burak Urfalioglu, Satuk Bugra Yapici, Durdu Mehmet Uzucek, Dervis Yildiz, Kemal Sener, Adem Kaya, Akkan Avci, Sadiye Yolcu

“…In such infectious diseases, it is difficult to predict the prognosis of the patients including discharge, hospitalization service, mortality probability in the EDs those are becoming much more crowded each day and several scoring systems have been improved. …”
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The Discovery and Characterization of Minimoon 2024 PT5 by Bryce T. Bolin, Larry Denneau, Laura-May Abron, Robert Jedicke, Kristin Chiboucas, Carl Ingebretsen, Brian C. Lemaux

“…Minimoons are asteroids that become temporarily captured by the Earth–Moon system. …”
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Análisis de competitividad de cuatro sistema- producto estatales de tilapia en México by Miroslava Vivanco Aranda, Francisco Javier Martínez Cordero, Isabel Cristina Taddei Bringas

“…En la agricultura y pesca en México, las cadenas productivas nacionales y estatales, identificadas como Sistema- Producto (SP) han sido con sideradas un objetivo de política pública sectorial para incrementar su competitividad. En los hechos, las acciones para fortalecerlas, no necesariamente han sido emprendidas desde el gobierno y/o instituciones. …”
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Colombia, Estados Unidos y seguridad nacional en los países andinos by Adrián Bonilla

“… El propósito de este trabajo es sistematizar algunos hechos que permitan comprender la diferencia de las agendas de seguridad nacional de los países andinos respecto de aquellas de Bogotá y Washington, a partir la ejecución del Plan Colombia. …”
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Long-term smoking contributes to aging frailty and inflammatory response by Huijin Hou, Yidi Chai, Ting Zhang, Yue Liang, Lan Huang, Xu Cao, Shufang Liang

“… In recent years, the health challenges linked to frailty in the elderly, particularly those worsened by cigarette smoke, have become more pronounced. However, quantitative studies examining the impact of smoking dosage on frailty in this population remain limited. …”
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Comparative efficacy of repurposed drugs lopinavir-ritonavir and darunavir-ritonavir in hospitalised COVID-19 patients: insights from a tertiary centre cohort by Dóra Paróczai, Dóra Paróczai, András Bikov, András Bikov, Andreea Blidaru, Emanuel Bobu, Ana Lascu, Ana Lascu, Cristian Ion Mot, Cristian Ion Mot, Stefan Mihaicuta, Stefan Mihaicuta, Stefan Frent, Stefan Frent

“…BackgroundDrug repurposing has become a widely adopted strategy to minimise research time, costs, and associated risks. …”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…<h4>Background</h4>Antimicrobial resistance (AMR) has become an emerging issue in the developing countries as well as in Bangladesh. …”
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Computer-assisted discovery of natural inhibitors for platelet-derived growth factor alpha as novel therapeutics for thyroid cancer by Hira Khalid, Farah Sattar, Iqra Ahmad, Valdir Ferreira de Paula Junior, Valdir Ferreira de Paula Junior, Umar Nishan, Umar Nishan, Riaz Ullah, Hanna Dib, Khaled W. Omari, Mohibullah Shah, Mohibullah Shah

“…Our top hits are non-mutagenic, can cross the blood-brain barrier, and inhibit p-glycoprotein, while the N-cis-feruloyltyramine has the potential to become a lead compound. The protein-ligand stability of the top 3 hits, namely cis-Grossamide K, Daturafoliside O, and N-cis-feruloyltyramine, and their interactions at the potential binding site of target protein were confirmed through molecular dynamic simulations. …”
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The pet trade of native species outside of their natural distributions within Australia is a biosecurity risk by Adam Toomes, Oliver C. Stringham, Stephanie Moncayo, Katherine G. W. Hill, Jacob Maher, Freyja Watters, Sebastian Chekunov, Pablo García‐Díaz, Lewis Mitchell, Joshua V. Ross, Phillip Cassey

“…So‐called “domestic non‐natives” have established new populations across several countries and, in some cases, become invasive. Here, we investigated the extent of the domestic trade of native Australian pet species outside of their natural distributions and determined whether such locations were climatically suitable for potential alien establishments. …”
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Development of the therapeutic regimen based on the synergistic activity of cyclophosphamide and double-stranded DNA preparation which results in complete cure of mice engrafted wi... by E. A. Potter, E. V. Dolgova, A. S. Proskurina, Ya. R. Efremov, O. S. Taranov, V. P. Nikolin, N. A. Popova, T. D. Dubatolova, D. D. Petrova, E. I. Vereschagin, A. M. Minkevich, O. M. Andrushkevich, S. I. Baiborodin, V. A. Rogachev, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…Nonetheless, this treatment apparently synchronizes TISCs in a cell cycle phase when they become sensitive to further drug treatments. We describe the regimen of synergistic DNA + CP activity against Krebs-2 ascites. …”
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How Do the Four Core Factors of High Entropy Affect the Electrochemical Properties of Energy‐Storage Materials? by Wenze Wang, Qian Zhang, Liting Yang, Guisheng Liang, Xuhui Xiong, Yifeng Cheng, Limin Wu, Chunfu Lin, Renchao Che

“…However, the Li+ diffusivity of HE‐LaNb3O9 at high temperature (60 °C) becomes faster than that of LaNb3O9, which is attributed to the alleviated lattice distortion at the high‐temperature, resulting in higher rate capability. …”
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Bridging incremental to transformative hazard management strategies on the Tule River Indian Reservation by Natalie Herbert, Caroline Beckman, Kerri Vera, Eric Coles, Thomas Kim, Seung-Hyun Cho, Gabrielle Wong-Parodi

“…Compounding hazards are becoming more common due to global environmental change. …”
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Early Outcomes With Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation by Shashank Shekhar, MD, Amar Krishnaswamy, MD, Grant Reed, MD, MSc, James Yun, MD, Rishi Puri, MD, PhD, Samir Kapadia, MD

“…In anatomically eligible patients, the potential benefit of debris capture may be considered especially as younger and lower risk patients become eligible for TAVR. Data from future trials and registries are required to further corroborate our findings.…”
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Los colectivos de apoyo y su influencia en el discurso de resistencia de las madres de personas desaparecidas by María Isabel del Palacio Ramírez

“…En este artículo se analizan las formulaciones de una madre con un hijo desaparecido, con el objetivo de identificar las formaciones discursivas que subyacen en el discurso de la entrevistada, y mostrar cómo a través de recursos lingüísticos y estrategias discursivas, se puede construir una particular representación de los hechos y de la resistencia que como integrante del colectivo opone al poder hegemónico de la autoridad. …”
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