To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway by Jia-Rong Gao, Xiu-Juan Qin, Zhao-Hui Fang, Li-Shan, Li-Ping Han, Hui-Jiang, Ming-Fei Guo, Nan-Nan Jiang

“…Type 2 diabetes mellitus (T2DM) has become a chronic disease, serious harm to human health. …”
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Perception of phage therapy and research across selected professional and social groups in Poland by Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki

“…., patients and their relatives, physicians and anyone who could potentially become infected with antibiotic-resistant bacteria. …”
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Aplicabilidad de las herramientas de gestión administrativa en las unidades empresariales de la zona metropolitana del municipio Libertador del estado Mérida, Venezuela by María Virginia Camacaro

“…La investigación de campo, exploratoria y descriptiva, siguió como estrategia metodológica la descripción sistemática de los hechos con base en las características de la muestra objeto de estudio, la cual estuvo integrada por 84 gerentes. …”
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Sandpiper Optimization Algorithm With Region Growing Based Robust Retinal Blood Vessel Segmentation Approach by Ibrahim AlMohimeed, Mohamed Yacin Sikkandar, A. Mohanarathinam, Velmurugan Subbiah Parvathy, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

“…The automated retinal vessel segmentation process becomes an essential tool to identify disease. Several retinal vessel segmentation models suffer from a lack of high generalization abilities and low accuracy due to the presence of complex symmetrical and asymmetrical patterns. …”
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Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis by Ana Maria Vega-Letter, Cynthia García-Guerrero, Liliana Yantén-Fuentes, Carolina Pradenas, Yeimi Herrera-Luna, Eliana Lara-Barba, Felipe A. Bustamante-Barrientos, Masyelly Rojas, María Jesús Araya, Nicole Jeraldo, Constanza Aros, Francisca Troncoso, Daniela Poblete, Angela Court, Alexander Ortloff, Jose Barraza, Francesca Velarde, Carlos Farkas, Claudio Carril, Noymar Luque-Campos, Gonzalo Almarza, Maximiliano Barahona, Jose Matas, Lucas Cereceda, Rocío Lorca, Jorge Toledo, Karina Oyarce, Rolando Vernal, Andrés Caicedo, Andrea del Campo, Yessia Hidalgo, Roberto Elizondo-Vega, Farida Djouad, Maroun Khoury, Fernando E. Figueroa, Patricia Luz-Crawford

“…Abstract Objective The inflammatory responses from synovial fibroblasts and macrophages and the mitochondrial dysfunction in chondrocytes lead to oxidative stress, disrupt extracellular matrix (ECM) homeostasis, and accelerate the deterioration process of articular cartilage in osteoarthritis (OA). …”
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Inhibition of platelet activation alleviates diabetes-associated cognitive dysfunction via attenuating blood-brain barrier injury by Fuxing Xu, Juan Hu, Xuying Li, Lan Yang, Shiqiu Jiang, Tao Jiang, Bo Cheng, Hailiang Du, Ruiduo Wang, Yingying Deng, Wei Gao, Yansong Li, Yaomin Zhu

“…Cognitive dysfunction has become the second leading cause of death among the diabetic patients. …”
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Influence of ESBL colonization status on gut microbiota composition during allogenic hematopoietic stem cell transplantation by Silvia Corcione, Ilario Ferrocino, Tommaso Lupia, Alessandro Busca, Gabriele Bianco, Chiara Dellacasa, Luisa Giaccone, Lucia Brunello, Sara Butera, Cristina Costa, Benedetto Bruno, Francesco Giuseppe De Rosa

“…Moreover, microbiota composition of colonized by ESBL that retained colonization after HSCT showed an increased in abundances of Akkermansia, Dialister, Erysipelotrichaceae and Methanobrevibacter when compared with patients that become negative at rectal swabs. From a clinical perspective, the evolution of this prospective pilot study will be to investigate markers of gut barrier functions, SCFA productions and to correlate the predictivity of these parameters with risk of invasive infections and clinical outcomes in allo-HSCT population.…”
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The Application of a Sodium Benzoate Salt-Nucleating Agent in Recycled Polyethylene Terephthalate: Crystallization Behavior and Mechanism by Meizhen Wang, Fuhua Lin, Tianjiao Zhao, Yapeng Dong, Xinyu Hao, Dingyi Ning, Yanli Zhang, Kexin Zhang, Dan Zhou, Jun Luo, Xiangyang Li, Bo Wang

“…The molecular chains of recycled polyethylene terephthalate (rPET) show breakage during daily use, causing poor crystallization and leading to mechanical properties that, when blended with the nucleating agent, become an effective method of solving this problem. …”
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Impact of a two-way short message service (SMS) to support maternally administered childhood mid-upper arm circumference monitoring and expand malnutrition screening in Kenya: the... by Jennifer A Unger, Barbra A Richardson, Kirkby D Tickell, Mareme M Diakhate, Jeanne L Goodman, Arianna Rubin Means, Keshet Ronen, Carol Levin, Esther M Choo, Catherine Achieng, Mary Masheti, Benson O Singa, Christine J McGrath

“…Introduction Over 52 million children under 5 years of age become wasted each year, but only 17% of these children receive treatment. …”
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Global burden of ischemic heart disease in older adult populations linked to non-optimal temperatures: past (1990–2021) and future (2022–2050) analysis by Lihui Liu, Lihui Liu, Yisong He, Yisong He, Gang Huang, Yangxi Zeng, Yangxi Zeng, Jiaan Lu, Ru He, Haiqing Chen, Yuheng Gu, Qingwen Hu, Bin Liao, Bin Liao, Juyi Wan, Juyi Wan

“…With the ongoing global climate change, understanding the impact of non-optimal temperatures on IHD burden becomes increasingly important, especially in vulnerable populations such as the older adult.MethodsThis study used data from the Global Burden of Disease Study 2021 (GBD 2021) to analyze the spatiotemporal trends of low and high temperatures on IHD burden in the older adult population (aged 60 and above) from 1990 to 2021. …”
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Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal by Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani

“…In cases of KDT ineffectiveness for seizure control in GLUT1DS patients, exploring alternative therapeutic strategies becomes imperative to managing symptoms while maintaining quality of life. …”
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Comprehensive safety and toxicity analysis of 2,2’-Bipyridine derivatives in combating MRSA biofilm formation and persistence by Priyanka, Priyanka, Mohini Sharma, Bhavna Vaid, Bhavna Vaid, Ram Bharti, Ram Bharti, Sachin Raut, Sachin Raut, R. S. Jolly, Neeraj Khatri, Neeraj Khatri

“…IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance. …”
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BÜYÜKŞEHİR SU VE ATIKSU İDARELERİNİN VERİMLİLİKLERİNİN VERİ ZARFLAMA ANALİZİ İLE ÖLÇÜMÜ - ATA ENVELOPMENT ANALYSIS MEASUREMENT OF PRODUCTIVITY OF MUNICIPALITIES WATER AND WASTE WAT... by Durmuş Acar, Gürkan Koç

“…Araştırmanın sonucuna göre İstanbul (İSKİ), Gaziantep (GASKİ), Kocaeli (İSU), Ankara (ASKİ), Diyarbakır (DİSKİ), geçmiş yıllara göre verimli olan kuruluşlardır. 2015 yılı itibariyle kuruluşların yüzölçümleri ile verimlilikleri arasında ilişki bulunmaktadır. 2014 ve 2015 yıllarında teknik etkinlik ile abone sayısı ve yine 2012 yılında toplam faktör verimliliği ile abone sayıları arasında ilişki bulunmuştur. …”
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Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

“…Despite the effectiveness of interventions, a significant number of patients experienced short-term disease progression.…”
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Türki Cumhuriyetlerin Banka Finansal Performanslarının Analizi by Şenol Babuşcu, Adalet Hazar, Özlem Karadağ Ak

“…Çalışmanın amacı, Azerbaycan, Kazakistan, Kırgızistan, Türkmenistan, Özbekistan ve Türkiye’nin de yer aldığı toplam altı Türki Cumhuriyetin bankacılık sisteminin geçmiş ve günümüzdeki finansal performanslarını Çok Kriterli Karar Verme tekniklerinden biri olan COPRAS yöntemi ile karşılaştırmaktır. …”
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Psicología forense y responsabilidad penal en Costa Rica by Frank Harbottle-Quirós

“…El presente artículo teórico resalta los aportes de la Psicología forense y la importante labor que desempeñan  psicólogos forenses en la elaboración de los dictámenes periciales, las cuales deben concluir sobre la capacidad mental de la persona evaluada al momento de los hechos delictivos mediante un análisis retrospectivo.  …”
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La nueva mentalidad urbana y la teneduría de libros por partida doble: Génova, Venecia y Florencia, siglos XIII a XVI by Abel María Cano-Morales, Carlos Mario Restrepo-Pineda, Omar Osvaldo Villa-Monsalve

“…El artículo presenta unas reflexiones iniciales sobre la Historia de la Contabilidad y el método histórico, en particular las implicaciones de la “Nueva Historia” en la Historia de la Contabilidad, en el entendido de que los hechos tienen sentido solo si se les considera en un contexto: Luca Pacioli y la revolución comercial del siglo XIII, el cambio de mentalidad en la forma de afrontar el mundo en el espacio y el tiempo, el mundo se percibe ahora de una forma cuantificada; para explicar el cambio de mentalidad en el Renacimiento se utiliza el concepto de Tiempo en dos momentos en la historia de Occidente: la Antigüedad y el Renacimiento; en este último periodo, el pensamiento moderno se va formando de acuerdo con unas condiciones sociales, a una práctica social e histórica, producto de la vida en las ciudades y en especial del comercio; el comercio sufre una revolución, se pasa de un comercio ambulante a un comercio “sedentario”, en materia de cuentas esta revolución significa un cambio de filosofía contable, al introducirse la partida doble en las ciudades del norte de Italia, pues ahora se integran e interrelacionan todos los elementos que constituyen el patrimonio, registrando sus cambios de estructura y los desarrollos de cada una de las variables del sistema. …”
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Evolution paths of urban forms influenced by landforms: Asynchrony but convergence by Chao Yang, Qiyan Huang, Qiong Xian, Meng Yuan, Xiaoming Cong, Lisha Xun, Jianxiong Cheng, Hongyi Pan

“…As terrain gradient increase, urban patches become separated and fragmented, making compact forms hard to establish. …”
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USO DEL LIBRO VIRTUAL PARA EL FORTALECIMIENTO DE LA LECTURA Y LA ESCRITURA EN EL ÁREA DE ESPAÑOL CON ESTUDIANTES DEL GRADO PRIMERO by Rosa Helena Perilla Barrero

“…Para llevar a cabo este trabajo de investigación en primer lugar se determinó el planteamiento del problema, estableciendo el tema, el contexto y la población a tener en cuenta como informantes, además se indagó en diferentes fuentes teóricas que permitieron respaldarlo, se manejó el enfoque cualitativo, metodología investigación acción, por lo que se aplicó la técnica de entrevista y la observación directa, realizando posteriormente el análisis de la información, llegando a concluir que la lecto escritura puede ser potenciada cuando se trabaja con herramientas tecnológicas como los libros virtuales. …”
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Perspectives of nurses and patient representatives on the morally competent nurse: An international focus group study by Chris Gastmans, Evelyne Mertens, Alvisa Palese, Brian Keogh, Francesca Apolloni, Johanna Wiisak, Catherine Mc Cabe, Maria Dimitriadou, Alessandro Galazzi, Michael Igoumenidis, Nikos Stefanopoulos, Paraskevi Charitou, Evridiki Papastavrou, Riitta Suhonen, Stefania Chiappinotto

“…Background: Across the world, healthcare systems have become increasingly complex, making it more difficult for nurses to act ethically when faced with moral dilemmas. …”
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