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  1. 4421
  2. 4422

    Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

    Published 2025-02-01
    “…Additionally, triglyceride-lowering benefits were evident, particularly in metabolically compromised individuals (Cohorts 2 and 3), where these effects were statistically significant. With high tolerability, these findings highlight Quercetin Phytosome™'s potential as a safe adjunctive therapy for hyperuricemia management, meriting further investigation in larger, randomized trials to confirm its efficacy and safety.Clinical Trial Registrationclinicaltrials.gov, identifier NCT06652035.…”
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  3. 4423

    Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

    Published 2025-02-01
    “…Quantitative data were analyzed using descriptive statistics. In the qualitative study, acceptability was defined as “the perception that a given treatment is agreeable, palatable, or satisfactory.” …”
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  4. 4424

    The role of the TAPSE/sPAP ratio as a predictor of mortality in Pulmonary Arterial Hypertension: Its value for patient risk stratification by Paul Palacios-Moguel, MD, Guillermo Cueto-Robledo, MD, Héctor González-Pacheco, MD, Jorge Ortega-Hernández, MD, María Berenice Torres-Rojas, MD, Dulce Iliana Navarro-Vergara, MD, Marisol García-Cesar, MD, Cinthia Alejandra González-Nájera, MD, Carlos Alfredo Narváez-Oríani, MD, Julio Sandoval, MD

    Published 2025-02-01
    “…Clinical, functional, echocardiographic, and haemodynamic variables, along with the TAPSE/sPAP ratio, were analysed based on etiological PAH subgroups and outcomes. Additional statistical measures, such as the area under the curve (AUC), net reclassification index (NRI), and integrated discrimination improvement, assessed the predictive ability of TAPSE/sPAP in combination with the ESC/ERS risk score, and other risk assessment strategies (COMPERA and Reveal Lite 2). …”
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  5. 4425
  6. 4426

    Prevalence and predictors of permanent pacemaker implantation in patients with aortic stenosis undergoing transcatheter aortic valve implantation: a prospective cohort study by Erlend Eriksen, Ronak Rajani, Sahrai Saeed, Svein Rotevatn, Daanyaal Wasim, Øyvind Bleie, Abukar Mohamed Ali, Erik Jerome Stene Packer, Håvard Keilegavlen

    Published 2025-02-01
    “…The secondary objectives were to investigate the temporal changes in permanent pacemaker implantation following TAVI and its impact on long-term prognosis.Design Prospective observational cohort study of patients with AS undergoing TAVI.Setting Single-centre study conducted at a tertiary hospital in Western Norway between 2012 and 2019.Participants Among 600 consecutive patients with severe AS who were treated with TAVI, 52 patients with permanent pacemaker prior to TAVI were excluded. …”
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  7. 4427

    Designing a Model for Credit Risk Assessment of Customers for Guarantees Issued by the Export Guarantee Fund of Iran via Artificial Neural Network Model by Farshid Ahmadi Sartakhti, Kambiz Hojabr Kiani, Seyed Shamsoddin Hoseini, Abbas Memarnejad

    Published 2023-12-01
    “…Based on available statistics and official records within the Iranian entity, it can be observed that between the Iranian calendar years of 1387 and 1397, this fund issued guarantees totaling $6.7 billion, with the largest claim, exceeding $317 million, originating from the credit guarantees provided for the benefit of creditors. …”
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  8. 4428

    Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort by Andersen JW, Høgh A, Lindholt JS, Søgaard R, Støvring H, Yderstræde KB, Sandbæk A, Dahl M

    Published 2025-02-01
    “…Pre- and post-screening healthcare utilization was analyzed, stratified by HbA1c levels: < 42 mmol/mol (normal), 42– 48 mmol/mol (pre-DM), and ≥ 48 mmol/mol (DM). Statistical analyses were performed using Poisson and logistic regression models to compare ratios of healthcare utilization before and after screening.Results: Of the participants, 16.5% had pre-DM, and 3.4% had DM. …”
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  9. 4429

    Dietary and lifestyle patterns identified through reduced rank regression and their association with insulin-related disorders: a prospective analysis from the Tehran Lipid and Glu... by Ebrahim Mokhtari, Hossein Farhadnejad, Farshad Teymoori, Mitra Kazemi Jahromi, Mehrnaz Nikkhah, Parvin Mirmiran, Fereidoun Azizi

    Published 2025-02-01
    “…Therefore, a suitable way to examine the combined effect of food consumption and its interaction with other lifestyle variables is to derive dietary patterns and lifestyle patterns using appropriate statistical methods. This study aimed to derive two dietary and lifestyle patterns related to hyperinsulinemia and insulin resistance(IR) using reduced rank regression(RRR) analysis. …”
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  10. 4430

    “¿Sabés qué es…?” Explicaciones de niños tutores en torno a vocabulario no familiar. Un estudio con niños de poblaciones urbano marginadas de Argentina/ “Do you know what it is…?”... by Florencia Alam, Maia Julieta Migdalek, María Laura Ramirez, Alejandra Stein, Celia Renata Rosemberg

    Published 2017-12-01
    “…In order to compare how these sequences were deployed in each type of activity, nonparametric statistical tests were used. The results showed a pre-eminence of the monologal modality and a greater use of strategies that resort to semantic aspects in reading situations. …”
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  11. 4431

    The triglyceride-glucose index trajectories are associated with cardiovascular diseases in people living with HIV: evidence from a prospective cohort study in China, 2005–2022 by Yinsong Luo, Liqin Sun, Yun He, Fang Zhao, Duo Shan, Fan Bu, Lingyun Ge, Xiaorui Li, Yiyao Hu, Xi Xiao, Hongzhou Lu, Jiaye Liu

    Published 2025-02-01
    “…While women also demonstrated a nonlinear association with a similar threshold (8.484), the relationship above the threshold was not statistically significant. Conclusions Higher baseline TyG index levels and the high-increasing trajectory were significantly associated with increased CVD risk in PLWH. …”
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  12. 4432
  13. 4433

    PENERAPAN PROJECT BASED LEARNING MODEL UNTUK MENINGKATKAN SIKAP ILMIAH MAHASISWA DALAM RANGKA MENGHADAPI ERA MERDEKA BELAJAR by Andik Purwanto, Desy Hanisa Putri, Dedy Hamdani

    Published 2021-04-01
    “…Data analysis was performed using descriptive statistics. The results of data analysis showed that the implementation of the Project Based Learning model in the Thermodynamics Subject for 3rd semester students of the Physics Education Study Program, FKIP, Bengkulu University, has an increase in scientific attitudes and learning outcomes. …”
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  14. 4434

    Perbandingan Metode Supervised Machine Learning untuk Prediksi Prevalensi Stunting di Provinsi Jawa Timur by M Syauqi Haris, Ahsanun Naseh Khudori, Wahyu Teja Kusuma

    Published 2022-12-01
    “…East Java Province has a stunting prevalence value of 26.8% based on data integration from the Ministry of Health and the Central Statistics Agency. This value is still relatively high because the minimum standard set by the World Health Organization (WHO) is 20%. …”
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  15. 4435
  16. 4436

    Assessing Mental Illness Referral Request Acceptance: A Nationwide E-Referral Data From Saudi Arabia by Alharbi AA, Aljerian NA, Alghamdi HA, Binhotan MS, Alsultan AK, Arafat MS, Aldhabib A, Aloqayli AI, Alwahbi EB, Horner RD

    Published 2025-02-01
    “…This study examined SMARC’s effectiveness in facilitating mental health service access by analyzing patient transfer acceptance rates between healthcare facilities and identifying factors influencing these rates.Methods: This retrospective cross-sectional study analyzed 9722 mental health electronic referrals within SMARC from January 2020 to December 2021. Descriptive statistics characterized referral patterns, while bivariate and multivariable logistic regression analyses identified factors associated with referral acceptance, calculating adjusted odds ratios (aORs) and 95% confidence intervals.Results: The system achieved an overall acceptance rate of 82.5%, with different patterns across age groups and regions. …”
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  17. 4437

    Metformin exerted tumoricidal effects on colon cancer tumoroids via the regulation of autophagy pathway by Roya Shabkhizan, Çığır Biray Avci, Sanya Haiaty, Marziyeh Sadat Moslehian, Fatemeh Sadeghsoltani, Ahad Bazmani, Mahdi Mahdipour, Leila Sabour Takanlou, Maryam Sabour Takanlou, Arezoo Rezaie Nezhad Zamani, Reza Rahbarghazi

    Published 2025-02-01
    “…Despite slight changes in released LDH contents, no statistically significant differences were achieved in terms of cell toxicity in MTF-exposed groups compared to the control tumoroids, indicating the insufficiency of MTF in the induction of tumor cell death (p > 0.05). …”
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  18. 4438

    Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study by Maik JM Beuken, Melanie Kleynen, Susy Braun, Kees Van Berkel, Carla van der Kallen, Annemarie Koster, Hans Bosma, Tos TJM Berendschot, Alfons JHM Houben, Nicole Dukers-Muijrers, Joop P van den Bergh, Abraham A Kroon, Iris M Kanera

    Published 2025-02-01
    “…To identify a subset of distinct, minimally redundant, predictive variables, we used the statistically equivalent signature algorithm. To describe the clusters, we applied measures of central tendency and variability, and we assessed the distinctiveness of the clusters through the emerged variables using the F test for continuous variables and the chi-square test for categorical variables at a confidence level of α=.001 ResultsWe identified 3 distinct clusters (including 4128/9188, 44.93% of all data points) among individuals with obesity (n=4128). …”
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  19. 4439
  20. 4440