The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…Further, anticipation of, and planning for, non-proportional hazards arising from response heterogeneity may have mitigated loss of statistical power. With the aim of improving the efficacy of belantamab mafodotin, other Phase III trials in the RRMM development program (DREAMM-7 and DREAMM-8) proceeded to evaluate the synergistic potential of combination regimens in earlier lines of treatment. …”
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THE IMPACT OF FIRM CHARACTERISTICS ON ACCRUALS AND REAL EARNINGS MANGEMENT OF LISTED MANUFACTURING FIRMS IN NIGERIA by Aisha Chado Muhammad

“…The results indicated; firm size has a consistent negative impact on both AEM and REM, with statistically significant results indicating that larger firms may face unique challenges related to financial reporting quality. …”
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Development of a psychological frailty index: results from the China health and retirement longitudinal study by Jinlong Zhao, Justina Yat Wa Liu, Justina Yat Wa Liu, Daniel Fernández, Stefanos Tyrovolas, Stefanos Tyrovolas, Stefanos Tyrovolas, Stefanos Tyrovolas

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LINE-1 methylation status and survival outcomes in colorectal cancer patients: A systematic review and meta-analysis by Akbar Bagheri, Tohid Jafari-Koshki, Leila Alizadeh, Mortaza Raeisi, Yaghoub Moaddab, Abbas Karimi

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A meta-analysis of the impact of TOE adoption on smart agriculture SMEs performance. by Adrian Nagy, Johan Tumiwa, Fitty Arie, Erdey László, Anas Ratib Alsoud, Main Al-Dalahmeh

“…<h4>Methods</h4>PRISMA technique was used to examine evidence from clinical trials, and clinical significance was determined using the GRADE approach. Statistical analysis was performed using the Fisher test to combine the results of several studies and Cohen's approach to interpreting effect sizes.…”
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Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia by Yu Zhang, Zhao Yin, Zurong Yao, Dan Xu, Xuejie Jiang, Xiaqi Nie, Dandan Chen, Hongsheng Zhou, Pengcheng Shi, Hui Liu, Qifa Liu, Guopan Yu

“…In contrast, the CLAG group had a median OS of 18.6 (95% CI 14.7–22.6) months and EFS of 10.7 (95% CI 6.6–14.8) months. Although not statistically significant, patients in the CLAG + Ven group showed a potential survival advantage compared to the CLAG group. …”
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Analysis of Gas Pipeline Failure Factors Based on the Novel Bayesian Network by Machine Learning Optimization by Shuangqing Chen, Shun Zhou, Zhe Xu, Yongbin Liu, Bing Guan, Xiaoyu Jiang, Wencheng Li

“…Subsequently, the pipeline risk analysis is conducted based on statistical data from the Pipeline and Hazardous Materials Safety Administration (PHMSA). …”
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Characteristic analysis and surgical exploration for acetabular roof fractures: Multicenter retrospective cohort study. by Ruipeng Zhang, Yingchao Yin, Wei Chen, Yan Zhuang, Shicai Fan, Chengla Yi, Gang Lyu, Longpo Zheng, Xiaodong Guo, Ming Li, Guangyao Liu, Zhiyong Hou, Yingze Zhang

“…Reduction quality and functional outcome showed no statistical difference in three subtypes (P<0.05). Reduction quality and functional outcome presented positive correlation in three subtype fractures (P<0.05). …”
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The Role of Using Motorized Diamond Burr Polisher Instrument in Minimizing the Recurrent Rate of Pterygium Excision by Sakar Abdulkarim Nidhamalddin

“…Corneal scar happens in only 1(2.2%) case of group A while in 11(24.4%) cases in group B, Corneal scar was statistically significant. In both groups the change of BCVA was significant but the visual change was more significant in group A in compare to group B. …”
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Prevalence of soil-transmitted helminths infection and associated risk factors among residents of Jigjiga town, Somali region, Eastern Ethiopia. by Abdlmenur Alewi Sedo, Ahmed Zeynudin, Tariku Belay, Mekdes Mekonen Belay, Ahmed Mohammed Ibrahim, Mohamed Omar Osman, Ramadan Budul Yusuf, Abdifatah Abdulahi

“…Bivariate and multivariate logistic regression analyses were performed, and statistical significance was declared at a level of p-value < 0.05 between the outcome and independent variables.…”
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Fine-tuning GBS data with comparison of reference and mock genome approaches for advancing genomic selection in less studied farmed species by Daniel Fischer, Miika Tapio, Oliver Bitz, Terhi Iso-Touru, Antti Kause, Ilma Tapio

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Delayed-release prednisone improves fatigue and health-related quality of life: findings from the CAPRA-2 double-blind randomised study in rheumatoid arthritis by Frank Buttgereit, Rieke Alten, Amy Grahn, Robert J Holt, Patricia Rice

“…General quality of life was assessed using the general score and individual domains of Functional Assessment of Cancer Therapy-General (FACT-G) and SF-36.Results The change from baseline to week 12 in FACIT-F score was statistically significantly different with DR prednisone/DMARD (3.8) versus placebo/DMARD (1.6; difference 2.2, p=0.0032). …”
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Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. by Caroline C McGrouther, Aaditya V Rangan, Arianna Di Florio, Jeremy A Elman, Nicholas J Schork, John Kelsoe, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

“…We find evidence of genetic heterogeneity delineating a statistically significant bicluster comprising a subset of BD cases which exhibits a disease-specific pattern of differential-expression across a subset of SNPs. …”
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Linear dimensional changes and surface hardness of acetal resin in different periods of artificial saliva immersion in comparison with heat cure acrylic. by Sura S. Khalid, Widad A. AL-Nakkash

“…Concerning linear dimensional change after processing: Nonsignificant difference between acrylic and acetal in BC, DA lines, statistically highly significant difference in AB line and significant difference in CD line. …”
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Knowledge, Attitude and Practice of Medical Students of Sulaimani Regarding Modern Lifestyle and Its Effect on Health by Bushra M. Ali, Saman Mohammed, Shajwan Akram, Saya Salar, Lezan Baxtiar, Lawen Ismail, Shad Nawzad

“…Chi square was used to get the association P value equal and less than (0.05) regarded statistically significant. Most of the students (82.1%) had heard about a modern lifestyle with highest percentage of participants (90.5%) from college of medicine, and (69.3%) knew that technology has a major role in creating a modern lifestyle, with a significant P value of (0.001). …”
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The negative impact of missing primary teeth with the importance of space maintainer among children attending the college of dentistry, hawler medical university in Erbil: Iraq. by Hozan Farid Tawfiq, Alaa Mahmud Mustafa

“…Using the SPSS software for statistical analysis by IBM of version 26 in which frequency table and Fisher Exact test was used and the level of significance was set at 0.05. …”
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Effects of Verbal and Tactile Cues on Gluteal Force Production and Broad Jump Distance by BJ Lehecka, Terra Daniels, Bryson Koester, Wyatt Kropp, Matthew Reeves, Ryan Waterson

“…Performance on the broad jump was measured in centimeters. Descriptive statistics and test-retest reliability via Pearson correlation coefficients were calculated, differences in performance between sexes were analyzed with an independent t-test, and changes in force production and jump distance from baseline were analyzed using a one-way ANOVA…”
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Shared decision-making competency and its associated factors among palliative care nurses: a cross-sectional study in China by Junchen Guo, Sishan Jiang, Yunyun Dai, Xianghua Xu, Chaoyi Liu, Yongyi Chen

“…The EA (β = 0.683, P<0.001), experiences of SDM training (β=-0.155, P<0.001) and educational background (β=-0.142, P = 0.007) were statistically significant factors influencing nurses’ SDM competency based on multiple linear regression analysis. …”
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Assessment of sleep problems in patients with Kawasaki disease: a survey-based study by Samar Tharwat, Mohammed Kamal Nassar

“…The total duration of sleep did not exhibit any statistically significant difference between patients with KD and healthy controls (p = 0.399). …”
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Evaluating GRU Algorithm and Double Moving Average for Predicting USDT Prices: A Case Study 2017-2024 by RAHMAT, Munirul ula, Zara Yunizar

“…DMA, in contrast, is a statistical method that filters market noise to identify long-term trends, making it more reliable for stable market conditions. …”
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