Žánr na hraně: inovativní rysy české záhadologické prózy by Іво Поспішил

“…Seskupení takových děl a skupin jejich autorů vytvořilo speciální kánon, který – jako jiné žánry nebo typy literatury – má své fanoušky a také ostré kritiky. …”
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Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit... by E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian

“…Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death. The inherited form of frontotemporal dementia can be caused by mutations in several genes, including the MAPT gene on chromosome 17, which encodes the tau protein. …”
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Sugarcane Bagasse-Derived Cellulose Nanocrystal/Polyvinyl Alcohol/Gum Tragacanth Composite Film Incorporated with Betel Leaf Extract as a Versatile Biomaterial for Wound Dressing by Luong Ngoc Diem, Selorm Torgbo, Indranil Banerjee, Kunal Pal, Udomlak Sukatta, Prapassorn Rugthaworn, Prakit Sukyai

“…Initial analysis of CNCs by transmission electron microscopy (TEM) showed nanosized particles of 104 nm in length and 7 nm in width. …”
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Influence of lemongrass and oregano essential oils and their combination on in vitro ruminal fermentation and greenhouse gas emissions in total mixed ration for dairy cows by Sara Glorio Patrucco, Alessandro Lotto, Martina Dorigo, Rita Fornaciari, Antonio Sagliano, Nicola Martinelli, Alessandra Cosani, Khalil Abid, Salvatore Barbera, Hatsumi Kaihara, Sonia Tassone

“…LEO reduced pH (−0.6%, p=0.004), while OEO increased oxidation capacity (+4.2%, p=0.004), but both parameters remained within physiological ranges. Canonical discriminant analysis confirmed distinct EOs effects, highlighting their potential as natural additives for improving ruminal fermentation and mitigating ruminant environmental footprint.…”
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3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis by Sayan Deb Dutta, Jeong Man An, Jin Hexiu, Aayushi Randhawa, Keya Ganguly, Tejal V. Patil, Thavasyappan Thambi, Jangho Kim, Yong-kyu Lee, Ki-Taek Lim

“…In a subcutaneous wound model, the 3D bioprinted COL@d-ECM/M2-Exo hydrogel displayed robust wound remodeling and hair follicle (HF) induction while reducing canonical pro-inflammatory activation after 14 days, presenting a viable therapeutic strategy for skin-related disorders.…”
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MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…Stemness markers were significantly downregulated following miRNA-21 inhibition: <i>OCT4</i> (<i>p</i> = 0.013), <i>SOX2</i> (<i>p</i> = 0.008), and <i>NANOG</i> (<i>p</i> = 0.0001), as well as β-catenin gene (<i>CTNNB1)</i> (<i>p</i> < 0.05), an important member of WNT signaling pathway. …”
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Development of Newly Formulated Nanoalumina-/Alkasite-Based Restorative Material by Reham M. Abdallah, Neven S. Aref

“…Nanotechnology offers considerable scope in dentistry to improve dental treatment, care, and prevention of oral diseases through the use of nanosized biomaterials. This study assessed the effect of incorporating alumina nanoparticles (Al2O3 NPa) to the recently introduced alkasite-based restorative material (Cention N) on its mechanical properties and surface topographical features. …”
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Effects of Ginseng and Echinacea on Cytokine mRNA Expression in Rats by Deniz Uluışık, Ercan Keskin

“…While the C group was fed a standard rat diet (Purina) ad libitum for a period of 40 days, the G and E groups animals received the same diet containing 0.5 g/kg of Panax ginseng root powder and 0.75 g/kg of Echinacea purpurea root powder, respectively. …”
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Climate change and the sustainable use of medicinal plants: a call for “new” research strategies by Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Lyndy J. McGaw, Javier Echeverría, Marce Takubessi, Marce Takubessi, Michael Heinrich, Michael Heinrich

“…., Boswellia sacra Flück., Crocus sativus L., Panax quinquefolius L., Pilocarpus microphyllus Stapf ex Wardlew., Rhodiola rosea L., and Warburgia salutaris (G.Bertol.) …”
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<i>Ex Vivo</i> Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study by Arijita Sarkar, Matthew C. Gallo, Jennifer A. Bell, Cory K. Mayfield, Jacob R. Ball, Mina Ayad, Elizabeth Lechtholz-Zey, Stephanie W. Chang, Osamu Sugiyama, Denis Evseenko, Jay R. Lieberman

“…Additionally, gene therapy was associated with an anti-inflammatory microenvironment; macrophages expressing canonical anti-inflammatory markers were more common in the gene therapy group. …”
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Linear Active Disturbance Rejection Control-Based Voltage Controller for Buck and Boost DC/DC Converters in DC Distribution Grids by Asimenia Korompili, Oemer Ekin, Marija Stevic, Veit Hagenmeyer, Antonello Monti

“…The formulation of the proposed L-ADRC model in the non-canonical form facilitates the employment of model-based estimation and feedback control methods, whose performance is determined through the design of several parameters. …”
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‘What a perennial delight is in hearing the French language spoken!’: Class, Language and Taste in the Maison de Molière’s French Performances in London (1871–1893) by Ignacio Ramos Gay

“…Through an examination of the reviews and impressions published by an array of professionals, including leading theatre critics at the time, dramatists, actors and aficionados, the research analyses the sociological, political, and aesthetic implications associated with the firm presence of the French language and French canonical plays in late Victorian London. The responses of theatre professionals inevitably raise the matter of high art by implicitly questioning which of the two theatrical traditions best reflect and recreate, through their language, such cultural standards: How is a language stylized to answer simultaneously to dramatic conventions and to expectations related to national sentiment? …”
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Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex by Ying-Wen Wang, Ching-Wei Luo

“…Results Distinct from the TGF-β1 inhibition on adipogenesis through canonical SMAD2/3 signaling, we clarified that TGF-β1 suppresses osteogenesis by inducing the formation of previously unidentified mixed SMADs mainly composed of SMAD1 and SMAD2, in which SMAD2 recruits more TGF-β1-induced co-repressors including HDAC1, TGIF1 and ATF3, whereas SMAD1 allows directing the whole transcriptional suppression complex to the cis-elements of osteogenic genes. …”
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Ankyloglossia and breastfeeding self-efficacy in newborns: a birth cohort study by Carlos Alberto Feldens, Moréniké Oluwátóyìn Foláyan, Lívia Mund de Amorim, Elisa Maria Rosa de Barros Coelho, Gabriela Fernandes Kern dos Santos, Paulo Floriani Kramer

“…Methods A birth cohort study was conducted involving mothers and newborns soon after childbirth at a public hospital in the city of Canoas, southern Brazil. At the hospital, the lingual frenum of newborns were clinically examined and classified using the Bristol Tongue Assessment Tool. …”
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Variations in the composition and frequency of celiac disease epitopes among synthetic wheat lines by Rahman Ebrahimzadegan, Ghader Mirzaghaderi

“…By searching the previously identified 121 epitopes and those with one mismatch in our amplicons, we found 54 different α-gliadins epitopes across our genotypes, four of which were new variants. The canonical epitopes were present in all lines, although their expression patterns varied. …”
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Lecture poétique des langues locales : cas de Nyanndra Mun (Proverbes) du Roi Salomon by Koffi Samuel N’ZI & Kouamé Gilles YAO

“…Au plan littéraire et linguistique, le corpus se révèle être un ancrage des assises des canons de la littérature et mise en fonctionnement des attentes stylistique, lexicale et sémantico-structurale, qui au demeurant satisfait les attentes des approches méthodologiques convoquées. …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…In fact, FNDC5 forms a co-precipitable complex with Chk1 alluding to possible intracellular actions for this canonically membrane-associated protein. Whereas FNDC5 overexpression in murine heart was cardioprotective, introduction of FNDC5-targeted shRNA into the myocardium was sufficient to trigger Bax up-regulation, ATR/Chk1 activation, oxidative stress, cardiac fibrosis, loss of ventricular function, and compromised animal survival. …”
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Development of a Solid-Phase Extraction (SPE) Cartridge Based on Chitosan-Metal Oxide Nanoparticles (Ch-MO NPs) for Extraction of Pesticides from Water and Determination by HPLC by Mohamed E. I. Badawy, Mahmoud A. M. El-Nouby, Abd El-Salam M. Marei

“…SEM and TEM explained that the nanoparticles have a spherical morphology and nanosize of 93.74 and 97.95 nm for Ch-CuO NPs and Ch-ZnO NPs, respectively. …”
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Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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The End of Akıncı Corps in The Ottoman Empire by Mustafa Alkan

“…They were the light cavalry forces and had a certain organizational structure. Those with manor were registered in the account book with their descriptions. …”
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