Büyük Birader’i Deneyimlemek: Bir Eleştirel Distopik Anlatı Örneği Olarak Orwell Keeping an Eye on You by Muzaffer Musab Yılmaz, Can Bora Gelberi

“…Günümüzde kanon olarak kabul edilen distopyalar büyük oranda yirminci yüzyılın ilk yarısında kaleme alınmıştır. …”
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Wnt1 Accelerates an Ex Vivo Expansion of Human Cord Blood CD34+CD38− Cells by Kamonnaree Chotinantakul, Patcharee Prasajak, Wilairat Leeanansaksiri

“…The expanded cells exhibited CD34+ CD38− CD133+ CD71low CD33low CD3− CD19− markers, expressed nanog, oct3/4, c-myc, and sox2 genes, and maintained differentiation potential into lymphoid, erythroid and myeloid lineages. …”
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Mechanisms of Cytotoxicity of Chemical Agents to Giant Cell Tumors: An In Vitro Study by Achmad Fauzi Kamal, Akbar Rizki Beni Asdi, Ahmad Jabir Rahyussalim, Rio Wikanjaya, Resda Akhra Syahrani, Tri Kurniawati, Septelia Inawati Wanandi

“…Multinucleated and spindle cells from cultured GCT patients, characterized by Nanog and Oct4 expression with RT-PCR, were directly administered, in vitro, with concentrations of 1%, 3%, and 5% of H2O2 and 75%, 85%, and 95% of ethanol for 10 minutes and concentrations of 0.003%, 0.005%, 0.01%, 0.03%, 0.1%, and 0.3% of H2O2 for 5 minutes and were incubated for 24 hours. …”
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WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation by Mario Mauthe, Wenqi Yu, Oleg Krut, Martin Krönke, Friedrich Götz, Horst Robenek, Tassula Proikas-Cezanne

“…By automated fluorescence-based high content analyses, we demonstrate that Staphylococcus aureus strains (USA300, HG001, SA113) stimulate autophagy and become entrapped in intracellular PtdIns(3)P-enriched vesicles that are decorated with human WIPI-1, an essential PtdIns(3)P effector of canonical autophagy and membrane protein of both phagophores and autophagosomes. …”
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The Determinants of Sexual Intercourse Before Age 16 Years Among Rural Jamaican Adolescents by Olaniyi J. Ekundayo, Joana Dodson-Stallworth, Michele Roofe, Inmaculada B. Aban, Laura H. Bachmann, Mirjam C. Kempf, John Ehiri, Pauline E. Jolly

“…We analyzed data for 469 sexually experienced adolescents attending public high schools in the rural parish of Hanover. Multivariate logistic regression was used to predict independent influences of these factors. …”
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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…Then, we use a network approach to link these shared genes to canonical pathways. Similarly, for all drugs treating the predisposing disease, we link their targets to pathways. …”
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Trellis Decoding for Qudit Stabilizer Codes and Its Application to Qubit Topological Codes by Eric Sabo, Arun B. Aloshious, Kenneth R. Brown

“…Here, we improve the scalability and practicality of their theory, show that it has strong structure, extend the results using classical coding theory as a guide, and demonstrate a canonical form from which the structural properties of the decoding graph may be computed. …”
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Farmers’ desire to make changes in their agricultural branches in the first wave of COVID-19 pandemic restrictions: The example of Türkiye by Yener Ataseven, Şule Coşkun Cevher, Celal Cevher

“…A survey study was conducted with broad participation and telephone interviews involving 2125 farmers in different production branches in 22 provinces. Nonlinear Canonical Correlation Analysis was used to analyze variables. …”
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Investigation of the influence of the heterogeneous structure of concrete on its strength by V.M. Volchuk, M.A. Kotov, Ye G. Plakhtii, O.A. Tymoshenko, O.H. Zinkevych

“…Analysis results of the canonical spectrum f(α), statistical characteristics of structural components: uniformity, orderliness Δ=f(α)q = 1−f(α)q = 100, and regularity K=f(α)q = -100−f(α)q = 100 were calculated. …”
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Extensive composable entropy for the analysis of cosmological data by Constantino Tsallis, Henrik Jeldtoft Jensen

“…Being extensive means that in the micro-canonical, or uniform, ensemble where all micro-state occur with the same probability, the entropy becomes proportional to N asymptotically: S(N)∝N for N→∞. …”
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Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic Mechanisms by Zhengjie Shen, Yongjuan Gu, Ruiyang Jiang, Heya Qian, Siyuan Li, Lixian Xu, Wenzhe Gu, Yun Zuo

“…Our previous study found that T96 could inhibit TNBC invasion via suppressing the canonical and noncanonical TGF-β signaling pathways. …”
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Association of a non-synonymous substitution in the condensin NCAPG gene with traits of eggs in laying hens by O. Yu. Barkova, M. G. Smaragdov

“…The results obtained are discussed in connection with the role of the canonical condensin complex in the compaction of chromatin and segregation of chromosomes.…”
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Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension by Jéssica Moraes Cruvinel, Elizabeth S. Greene, Rachel W. Read, Kichoon Lee, Sami Dridi, Paula R. Chen

“…Culture at 1% O2 resulted in increased abundance of HIF1α, a canonical protein stabilized during hypoxia, thus confirming effectiveness of the treatment. …”
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From physical activity patterns to cognitive status: development and validation of novel digital biomarkers for cognitive assessment in older adults by Ling-Jie Fan, Feng-Yi Wang, Jun-Han Zhao, Jun-Jie Zhang, Yang-An Li, Jia Tang, Tao Lin, Quan Wei

“…Demographic characteristics were also incorporated, and multimodal data fusion was achieved through canonical correlation analysis. We then developed explainable machine learning models, primarily random forest, optimized with hyperparameters, to predict individual cognitive function status. …”
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Addressing genome scale design tradeoffs in Pseudomonas putida for bioconversion of an aromatic carbon source by Deepanwita Banerjee, Javier Menasalvas, Yan Chen, Jennifer W. Gin, Edward E. K. Baidoo, Christopher J. Petzold, Thomas Eng, Aindrila Mukhopadhyay

“…However, sustainable feedstocks pose a challenge due to incomplete high-resolution metabolic data for non-canonical carbon sources required to curate GSMM and identify implementable designs. …”
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Mapping the Discourse. Architecture Periodicals in/for the Teaching of Architecture History by Gaia Caramellino, Valeria Casali, Nicole De Togni

“…On the one hand, the cross-reading of “journal biographies” and the study of the “anatomy” of diverse genres of magazines contribute to question canonical interpretations and timeframes of a 20th century architectural history still centered on the European and North American editorial scene, offering a more nuanced understanding of the times and forms of production of architectural culture. …”
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X-ray emission from hot gas and XRBs in the NGC 5846 galaxy by Kyadampure Anil, Vagshette Nilkanth, Patil Madhav

“…Among 90, only one source exhibits an X-ray luminosity greater than 1039ergs−11{0}^{39}\hspace{0.33em}{\rm{erg}}\hspace{0.33em}{{\rm{s}}}^{-1}, exceeding the Eddington limit for a canonical mass of a neutron star and occupies a position in the hard region of the X-ray color–color plot. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…Single-cell RNA sequencing (scRNA-seq) of TNBC cells after paclitaxel treatment revealed upregulation of innate immune programs canonically associated with interferon response and downregulation of cell cycle progression programs. …”
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NLRP3 Inflammasome Simultaneously Involved in Autophagy and Phagocytosis of THP-1 Cells to Clear Aged Erythrocytes by Qin Li, Fengyong Zhao, Jiamin Zhang, Ying Yang, Zhonghui Guo, Chen Wang, Qixiu Yang, Ying Sun, Ziyan Zhu

“…The occurrence of autophagy was dominated by microtubule-associated protein 1A/1B-light chain 3- (LC3-) associated phagocytosis accompanied by canonical autophagy. A negative correlation exists between the clearance of RBCs by THP-1 cells and the degree of autophagy. …”
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Unraveling TGF-β1’s Role in Mediating Fibrosis and Cell Death in Feline Kidney Cells by Chanyanuch Intachat, Phongsakorn Chuammitri, Benjaporn Sornpet, Prapas Patchanee, Nawin Manachai, Kakanang Piyarungsri

“…TGF-β1 signaling through the non-canonical/smad-independent pathway activates mitogen-activated protein kinase (MAPK) signaling, which is linked to fibrosis and apoptosis. …”
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