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1741
La genealogía de los niños de la calle y su educación en los Centros de Internamiento en México
Published 2010-01-01“…El problema de los sujetos menores "delincuentes" no es problema de justicia, es un problema de educación; para tal fin debe hacerse cargo una institución educativa que tenga la infraestructura y los recursos pedagógicos para atenderlos.…”
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1742
Emerging role of exosomes in cancer therapy: progress and challenges
Published 2025-01-01“…Abstract This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. …”
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1743
¿A lo imposible nadie está obligado? Una mirada crítica de su aplicación dentro del sistema penal colombiano a propósito de la obligación alimentaria
Published 2015-01-01“…En este artículo de reflexión se exponen algunos comentarios críticos rela cionados con el dictum de Ulpiano: Ultra posse nemo obigatum 1 , común mente utilizado como mecanismo de defensa en los delitos contra la asisten cia alimentaria en beneficio del ascendiente irresponsable, e irrespetado, para efectos de acusación por la omisión del progenitor a cuyo cargo se encuentran los hijos, lo cual puede degenerar en la lesión o puesta en peligro de la vida u otros derechos a favor de su descendiente, siendo exigible en contra de aquel la superación de este paradigma a toda costa.…”
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1744
Vender el territorio
Published 2024-01-01“…Por un lado, revelan el rol que tuvieron las estrategias de los agentes inmobiliarios a cargo de la tarea y, más ampliamente, remiten a los consensos entre quienes comercializaban y los muy diversos sectores que seleccionaban localizaciones y sitios para vivir, que en conjunto iban construyendo la expansión metropolitana. …”
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1745
Mathematical Model and Algorithm for the Reefer Mechanic Scheduling Problem at Seaports
Published 2017-01-01“…Refrigerated containers, also known as reefers, are used in transportation of temperature sensitive cargo, such as perishable fruits. …”
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1746
Mesenchymal Stem Cell-derived Exosomes: Novel Therapeutic Approach for Inflammatory Bowel Diseases
Published 2023-01-01“…As double membrane-encapsulated nanovesicles (30-150 nm), exosomes (Exos) shuttle between different cells to mediate intercellular communication and transport active cargoes of paracrine factors. The anti-inflammatory and immunomodulatory activities of mesenchymal stem cell (MSC)-derived Exos (MSC-Exos) provide a rationale for novel cell-free therapies for inflammatory bowel disease (IBD). …”
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1747
Gene Therapy for Glioblastoma Multiforme
Published 2025-01-01“…The possible benefits of combining gene therapy with standard GBM treatments will also be covered.…”
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1748
Functional large-conductance calcium and voltage-gated potassium channels in extracellular vesicles act as gatekeepers of structural and functional integrity
Published 2025-01-01“…During their transportation from the donor to the recipient cell EVs face differential ionic concentrations, which can be detrimental to their integrity and impact their cargo content. EVs are known to possess ion channels and transporters in their membrane but neither the function nor the role of these channels in EVs is known. …”
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1749
Extracellular vesicular microRNAs and cardiac hypertrophy
Published 2025-01-01“…In this review, we briefly review recent advancements in EV research, especially on biogenesis, cargoes and its role in cardiac hypertrophy. We then describe the latest findings regarding EV-derived miRNAs, highlighting their functions and regulatory mechanisms in cardiac hypertrophy. …”
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1750
Contribuições da Teoria da Inoculação e o papel didático da gamificação como ferramenta de combate à desinformação política
Published 2023-04-01“…Por fim, apresenta uma abordagem exploratória dos conceitos em torno da “inoculação psicológica” e sua aplicação em games educativos como mecanismo para mitigar os impactos da disseminação de conteúdos falsos ou politicamente nocivos nas redes sociais.…”
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1751
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1752
In Vitro Anthelmintic Activity of Ethanol Stem Bark Extract of Albizia ferruginea (Guill. & Perr.) Benth
Published 2021-01-01“…The effect of AFE and its fractions on the anthelminthic activity of mebendazole and albendazole were also determined using the adult worm (P. posthuma) motility assay. …”
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1753
The concept and significance of registration and permit-licensing procedures in the activities of the National Police
Published 2022-09-01“…The author’s definition of the concept of “registration and permit-licensing procedures in the activities of the National Police” has been proposed – these are successive legalized actions of a service nature, which are carried out by police bodies in the process of providing police services, upon completion of which an individual or legal entity receives a document (permit or license), which allows you to carry out various operations with objects of the permit system, items of individual protection and active defense, or provide specific services, in particular, guarding, maintenance of shooting ranges, transportation of oversized cargo.…”
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1754
Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells
Published 2013-01-01“…A general expansion of the ER does not affect global protein redox status until an extensive production of cargo proteins has started.…”
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1755
What Trucking Deregulation Did for Florida's Produce and Ornamentals
Published 2005-04-01“…Prior to that time, trucking firms had to seek federal permission to haul many types of cargoes and there were restrictions on the rates that could be charged (note: in practice, rate restrictions prevented carriers from lowering their charges more often than the reverse). …”
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1756
PROSPECTS FOR EXPORT DEVELOPMENT OF TRANSPORT AND LOGISTICS SERVICES OF RUSSIA
Published 2020-09-01“…Taking into account the large volume of world cargo transport by sea, the development of seaports is of great importance. …”
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1757
Joyce, Rossetti, Dante. L’edizione “preraffaellita” della "Vita Nuova" nella biblioteca e nell’immaginario di James Joyce
Published 2025-01-01“… Grazie alle ricostruzioni della biblioteca personale di Joyce (Ellmann, 1977; Power 2018), ci è noto che l’edizione della Vita Nuova acquistata dallo scrittore è una prestigiosa ristampa (datata 1911) del libello di Dante, illustrata dai quadri di Dante Gabriel Rossetti, pubblicata per la prima volta in Italia nel 1902 per Roux e Viarengo. …”
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1758
Itinerari e luoghi visitati tra organizzazione e reinterpretazione: creazione di uno spazio-tempo turistico nei villaggi lobi di Burchina Faso
Published 2013-01-01“…Nei villaggi lobi di Burkina Faso nuovi flussi turistici e conseguenti fenomeni di patrimonializzazione vanno disegnando un assetto regionale che risponde al modello turistico tradizionale legato alle “cose da vedere e da fare”. Dallo spazio museale a quello del villaggio, le relazioni tra i diversi protagonisti assumono una forma sempre più formale e standardizzata, anche se ogni singola situazione lascia intravvedere margini di manovra e sperimentazioni in atto. …”
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1759
Projection-Based Adaptive Backstepping Control of a Transport Aircraft for Heavyweight Airdrop
Published 2015-01-01“…The complex nonlinear uncertainty of the aircraft-cargo model is factorized into a known matrix and an uncertainty function, and a projection-based adaptive approach is proposed to estimate this function. …”
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1760
Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation
Published 2025-01-01“…One way to achieve this is by asymmetric cell division (ACD), characterized by an unequal distribution of cellular cargo, resulting in divergent daughter cells already after the first division—one being more destined to an effector and the other more to a memory fate. …”
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