Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis by U. Gomez-Pinedo, J.A. Matías-Guiu, L. Torre-Fuentes, P. Montero-Escribano, L. Hernández-Lorenzo, V. Pytel, P. Maietta, S. Alvarez, I. Sanclemente-Alamán, L. Moreno-Jimenez, D. Ojeda-Hernandez, N. Villar-Gómez, M.S. Benito-Martin, B. Selma-Calvo, L. Vidorreta-Ballesteros, R. Madrid, J. Matías-Guiu

“…We also analyzed the ability of transfected HOG cells to proliferate and differentiate into oligodendrocytes. …”
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Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis by U. Gomez-Pinedo, J.A. Matías-Guiu, L. Torre-Fuentes, P. Montero-Escribano, L. Hernández-Lorenzo, V. Pytel, P. Maietta, S. Alvarez, I. Sanclemente-Alamán, L. Moreno-Jimenez, D. Ojeda-Hernandez, N. Villar-Gómez, M.S. Benito-Martin, B. Selma-Calvo, L. Vidorreta-Ballesteros, R. Madrid, J. Matías-Guiu

“…We also analyzed the ability of transfected HOG cells to proliferate and differentiate into oligodendrocytes. …”
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Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients by L. Johana Madroñero, Eliana P. Calvo, Carolina Coronel-Ruiz, Myriam L. Velandia-Romero, María Angélica Calderón-Peláez, Jhann A. Arturo, Adriana P. Franco-Rodríguez, Ricardo Gutiérrez-Pérez, Lady S. López, Félix G. Delgado, Sigrid J. Camacho-Ortega, Lilia J. Bernal-Cepeda, Sonia P. Bohórquez, Jaime E. Castellanos

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Mid-term outcomes of percutaneous pulmonary valve replacement with Edwards-Sapien bioprosthesis in native right ventricular outflow tract by Yassin Belahnech, Gerard Martí-Aguasca, Laura Dos-Subirà, Pedro Betrian-Blasco, Bruno García del Blanco, Maria Calvo-Barceló, Eduard Ródenas-Alesina, Antonia Pijuan-Domènech, Ferran Gran, Queralt Ferrer, Gemma Giralt-García, Berta Miranda, Blanca Gordon, Víctor González-Fernández, José A. Barrabés, Ferran Roses-Noguer, Ignacio Ferreira-González

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CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization. by Gowtham A Rao, Azza Shoaibi, Rupa Makadia, Jill Hardin, Joel Swerdel, James Weaver, Erica A Voss, Mitchell M Conover, Stephen Fortin, Anthony G Sena, Chris Knoll, Nigel Hughes, James P Gilbert, Clair Blacketer, Alan Andryc, Frank DeFalco, Anthony Molinaro, Jenna Reps, Martijn J Schuemie, Patrick B Ryan

“…Moreover, expected clinical events like laboratory tests, treatments, and repeated diagnoses were also observed. For AD, although one PA identified considerably fewer patients, absence of notable differences in clinical characteristics between the two cohorts suggested similar specificity.…”
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The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI) Attenuates Elastase-Induced Emphysema in Mice by Bruno Tadeu Martins-Olivera, Rafael Almeida-Reis, Osmar Aparecido Theodoro-Júnior, Leandro Vilela Oliva, Natalia Neto dos Santos Nunes, Clarice Rosa Olivo, Marlon Vilela de Brito, Carla Máximo Prado, Edna Aparecida Leick, Mílton de Arruda Martins, Maria Luiza Vilela Oliva, Renato Fraga Righetti, Iolanda de Fátima Lopes Calvo Tibério

“…A reduction in the number of MUC-5-positive cells in the airway walls was also observed. Conclusion. rBbKI reduced elastase-induced pulmonary inflammation and extracellular matrix remodeling. rBbKI may be a potential pharmacological tool for COPD treatment.…”
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Geohazard features of the Tyrrhenian Calabria by Daniele Casalbore, Alessandro Conforti, Francesca Budillon, Eleonora Martorelli, Eleonora Morelli, Martina Pierdomenico, Alessandro Bosman, Giovanni De Falco, Gabriella Di Martino, Francesco Giseppe Falese, Sara Innangi, Renato Tonielli, Chiara Adami, Isabella Foderà, Erika Lai, Mariangela Diana Lodi, Valeria Lo Presti, Ennio Marsella, Cristian Montanaro, Andrea Sposato, Francesco Latino Chiocci

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CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization by Gowtham A. Rao, Azza Shoaibi, Rupa Makadia, Jill Hardin, Joel Swerdel, James Weaver, Erica A. Voss, Mitchell M. Conover, Stephen Fortin, Anthony G. Sena, Chris Knoll, Nigel Hughes, James P. Gilbert, Clair Blacketer, Alan Andryc, Frank DeFalco, Anthony Molinaro, Jenna Reps, Martijn J. Schuemie, Patrick B. Ryan

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Geohazard features of the Gulf of Naples and Pontine Islands (Eastern Tyrrhenian Sea) by Francesca Budillon, Eleonora Martorelli, Alessandro Conforti, Giovanni De Falco, Alessandro Bosman, Gabriella Di Martino, Marco Firetto Carlino, Martina Misuraca, Sara Innangi, Martina Pierdomenico, Andrea Sposato, Renato Tonielli, Daniele Casalbore, Roberto Capperucci, Aida Maria Conte, Francesco G. Falese, Michela Ingrassia, Ennio Marsella, Cristian Montanaro, Eleonora Morelli, Roberto Sisinni, Francesco L. Chiocci

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Direct collaboration between hospitals and NGOs, an essential tool to reinforce linkage to care in people living with HIV by Teresa Aldámiz-Echevarria, Chiara Fanciulli, Mónica Lopez, Leire Perez, Francisco Tejerina, David Sanchez, Blanca Lodeiros, Juan Carlos López, Juan Berenguer, Jose Maria Bellon, Maria Ferris, Mario Blazquez, Almudena Calvo, Mario Domene, Oswaldo Vegas, Carmen Rodriguez, Patricia Muñoz, Paloma Gijon, Pedro Montilla, Elena Bermudez, Maricela Valerio, Roberto Alonso, Belen Padilla, Critina Ventimilla, Cristina Diez

“…Program targeted PLHIV who were neither receiving antiretroviral treatment (ART) nor on medical follow-up (FU); but also, individuals at risk who underwent screening tests at the NGO and, if positive, were referred for confirmation. …”
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Correction to: Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network by Agnieszka Dzioba, Daniel Aalto, Georgina Papadopoulos-Nydam, Hadi Seikaly, Jana Rieger, Johan Wolfaardt, Martin Osswald, Jeffrey R. Harris, Daniel A. O’Connell, Cathy Lazarus, Mark Urken, Ilya Likhterov, Raymond L. Chai, Erika Rauscher, Daniel Buchbinder, Devin Okay, Risto-Pekka Happonen, Ilpo Kinnunen, Heikki Irjala, Tero Soukka, Juhani Laine, Head and Neck Research Network

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Osteoartrose lombossacra em leoa (Panthera leo) by Eduardo Augusto Terra Rossi de Barros, Paulo Fernandes Marcusso, Giovanna Valverde Magalhães Barbosa, Henrique Scomparin Guardia, Sônia Rumiko Suzuki França, Giovani Dal'Bó, Michelle Falcade Forti, Guilherme Guindolin Galassi, Fábio Henrique Viaceli Conforti, Daniela Pereira Bonini, Renato Leite Leonardo, Renata Paulino Xavier, Luciana Facco de Andrade, Everton dos Santos Cirino, Jorge Aparecido Salomão Júnior

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Development and Optimization of a Multiplex Real-Time RT-PCR to Detect SARS-CoV-2 in Human Samples by Camilo Castellar-Mendoza, María-Angélica Calderón-Peláez, Jaime E. Castellanos, Myriam L. Velandia-Romero, Carolina Coronel-Ruiz, Sigrid Camacho-Ortega, Lilia J. Bernal-Cepeda, Lady López-Ibarra, Jhann A. Arturo, Félix G. Delgado, Hernando Gutierrez-Barbosa, Sonia Bohorquez-Avila, Johanna Madroñero, Zayda L. Corredor-Rozo, Sandra J. Perdomo-Lara, Angela Fonseca-Benitez, Eliana Calvo

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Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain by Jordi Antón, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Rosa Bou, Judith Sánchez Manubens, Sonia Carriquí Arenas, Joan Calzada Hernández, Violetta Bittermann, Carolina Estepa Guillén, Juan Mosquera Angarita, Lucía Rodríguez Díez, Estíbaliz Iglesias, Miguel Marti Masanet, Berta Lopez Montesinos, Maria I. González Fernández, Alfonso de Lossada, Carmen Peral, Mónica Valderrama, Noelia Llevat, María Montoro Álvarez, Immaculada Calvo Penadés

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Length of stay after colorectal surgery in Italy: the gap between “fit for” and “actual” discharge in a prospective cohort of 4529 cases by Lorenzo Pandolfini, Duccio Conti, Piercarlo Ballo, Silvia Rollo, Alessandro Falsetto, Gian Matteo Paroli, Paolo Ciano, Michele Benedetti, Leonardo Antonio Montemurro, Giacomo Ruffo, Massimo Giuseppe Viola, Felice Borghi, Gianandrea Baldazzi, Massimo Basti, Pierluigi Marini, Mariano Fortunato Armellino, Vincenzo Bottino, Giovanni Ciaccio, Alessandro Carrara, Gianluca Guercioni, Marco Scatizzi, Marco Catarci, the Italian ColoRectal Anastomotic Leakage (iCral) study group

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Impact of primary care benefits on healthcare utilisation and estimated out-of-pocket expenses in urban, rural and remote settings in the Philippines by Antonio L Dans, Arianna Maever L Amit, Leonila F Dans, Gillian Sandigan, Regine Ynez H De Mesa, Mia P Rey, Josephine T Sanchez, Cara Lois T Galingana, Nannette Bernal-Sundiang, Maria Rhodora N Aquino, Johanna Faye E Lopez, Janelle Micaela S Panganiban, Romelei Camiling-Alfonso, Jose Rafael A Marfori, Ramon Pedro Paterno, Carol Stephanie Chua Tan-Lim, Noleen Marie Fabian, Chad Lester Lastrilla, Miguel Callo

“…The urban site experienced the lowest increase in utilisation, and the smallest reduction in estimated OOP expenses, which was also not statistically significant. Implementing primary care benefits will necessitate contextualised approaches to avoid the inadvertent aggravation of inequities in healthcare.…”
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Ten practical guidelines for microclimate research in terrestrial ecosystems by Pieter De Frenne, Rémy Beugnon, David Klinges, Jonathan Lenoir, Pekka Niittynen, Sylvain Pincebourde, Rebecca A. Senior, Juha Aalto, Kryštof Chytrý, Phillipa K. Gillingham, Caroline Greiser, Eva Gril, Stef Haesen, Michael Kearney, Martin Kopecký, Peter C. le Roux, Miska Luoto, Ilya Maclean, Matěj Man, Rachel Penczykowski, Liesbeth van denBrink, Stijn Van de Vondel, Karen De Pauw, Jonas J. Lembrechts, Julia Kemppinen, Koenraad Van Meerbeek

“…The paper is structured as a chronological guide, leading the reader through each step necessary to conduct a comprehensive microclimate study. At the end, we also discuss further research avenues and development in this field. …”
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Anxiety and depression in people with epilepsy during and one year after the COVID‐19 pandemic by Iris E. Martínez‐Juárez, Jimena Gonzalez‐Salido, Jimena Colado‐Martinez, Irving Fuentes‐Calvo, Santiago Philibert‐Rosas, E. Rodrigo Velásquez‐Coria, Salvador Martínez‐Medina, Mijail A. Rivas‐Cruz, Eithel Valenzuela‐Mendivil, Karen E. Guzmán‐Sánchez, Elizabeth M. Ruiz‐Peñaflor, Arnold R. Thomson‐Cerna, Emilia M. González‐Villagómez, Jimena Armenta‐Báez, Andrea Santos‐Peyret, Aurelio Jara‐Prado, Adriana Ochoa‐Morales, Daniel Crail‐Meléndez, Ángel Ruiz‐Chow, Mario A. Sebastián‐Díaz

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Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13]) by A. DeMichele, A. C. Dueck, D. Hlauschek, M. Martin, H. Burstein, G. Pfeiler, N. Zdenkowski, A. Wolff, M. Bellet-Ezquerra, E. Winer, M. Balic, K. Miller, M. Colleoni, D. Lake, G. Rubovsky, D. Cameron, J. Balko, C. F. Singer, Z. Nowecki, H. Iwata, N. Wolmark, K. A. Parraga, H. Rugo, G. G. Steger, T. Traina, G. Werutsky, D. Czajkowska, O. Metzger, S. El-Abed, K. P. Theall, R. D. Lu, P. O’Brien, C. Fesl, E. Mayer, M. Gnant

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Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study by Regina Peña-Enríquez, Begoña Bermejo, Marina Pollán, Alejandra Díaz-Chacón, Yolanda Jerez Gilarranz, José J Ponce Lorenzo, Antonio Fernández Aramburo, Blanca Cantos Sánchez de Ibargüen, Ana Santaballa Bertrán, Elena Galve-Calvo, Álvaro Jiménez-Arranz, Yolanda Fernández, María Eva Pérez, Susana De La Cruz, Antonio Anton-Torres, Fernando Moreno, María Jesús Vidal-Losada, María Helena López-Ceballos, Isabel Blancas, María José Echarri, Raúl Rincón, Rosalía Caballero, Ángel Guerrero-Zotano, Silvia Guil-Luna, Juan de la Haba-Rodríguez

“…Through the PPI network, we also identified a cluster of cell-cycle regulation genes like MYC, FOXM1, or PTEN. …”
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