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13301
Endangered clonal plant Rosa persica: Limited genetic and clonal diversity, abundant leaf phenotypic variation
Published 2025-01-01“…The clone has an average area of 17.4 m2 and produces 10.35 ramets. And the clonal architecture tends to be guerrilla growth form. …”
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Effects of Optimized Fertilization and Organic Fertilizer Subsitution Technology on the Growth and Soil Fertility of Chinese Flowering Cabbage
Published 2024-10-01“…T2 had the highest yield (28.15 t/hm2), followed by T3 (26.35 t/hm2). The nutrient content was not affected by organic substitution. …”
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Association study of the JAK/STAT signaling pathway with susceptibility to COVID-19 in moroccan patient and in-silico analysis of rare variants
Published 2025-01-01“…Adjustment for age and gender revealed a significant association between TYK2 p.Gly363Ser (p=0.036) and COVID-19 infection, where the GA variant exhibited protective effects (0.6361 [0.3405–1.1884], p=0.035). Additionally, STAT2 p.Met594Ile showed an association to COVID-19 risk (p=0.042), with heterozygous GC being linked to infection (p=0.037, OR=2.7135 [0.5684 -12.9532]). …”
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Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial
Published 2025-01-01“…In analysis of participants with good medication compliance, 60 mg/day CEP significantly shortened the time to negative (difference=-0.87 days, HR = 1.56, 95% CI 1.03–2.37, p = 0.035). Adverse events were not different among the three groups, and no serious adverse events occurred. …”
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Interaction between walkability and fine particulate matter on ischemic heart disease: A prospective cohort study in China
Published 2025-01-01“…Results: Over a median follow-up of 5.14 years, 1735 incident cases of IHD were identified. Adjusted HRs (95 % CIs) were 1.56 (1.34–1.81) per 10 μg/m3 increase in PM2.5 and 0.96 (0.94–0.98) per 10-unit increase in walkability, with both exposures exhibiting non-linear dose-response relationships. …”
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
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13311
Development of 3D-Printed Serpentine Fluidic Channel Integrated with Heating Element for Loop-Mediated Isothermal Amplification (LAMP) Process
Published 2025-01-01“…The developed portable LAMP device consisting of a fabricated serpentine fluidic channel on a PTC 230 heating element allows the sample to be heated at 65°C for 35 minutes. Sample flow inside each serpentine fluidic channel was measured and compared with the expected flow time of 35 minutes. …”
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Development and validation of a screening tool for sepsis without laboratory results in the emergency department: a machine learning studyResearch in context
Published 2025-02-01“…In external testing, the AUROC decreased to 0.766 (95% CI, 0.758–0.774) for LR, 0.725 (95% CI, 0.717–0.733) for RF, and 0.735 (95% CI, 0.728–0.742) for XGB. In addition, the AUROC for the qSOFA, MEWS, and SIRS scores in external validation cohort were 0.579 (95% CI, 0.563–0.596), 0.600 (95% CI, 0.578–0.622), and 0.704 (95% CI, 0.683–0.725), respectively. …”
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Fact-finding and risk factor analysis of chemotherapy-induced nausea and vomiting in children with solid tumors: a prospective observational study
Published 2025-01-01“…. >6 years: OR = 0.322, 95% CI 0.145 ~ 0.715), female (OR = 2.034, 95% CI 1.035 ~ 3.994), duration of chemotherapy block (OR = 1.611, 95%CI 1.039 ~ 2.499), and antiemetic regimen (5-hydroxytryptamine-3 receptor antagonists (5HT3RA) vs. 5HT3RA + dexamethasone: OR = 0.395, 95% CI 0.171 ~ 0.914) were statistically significant in complete CIV control (P < 0.05). …”
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UBICU: A Gamified Respiratory Incentive System for Pulmonary Re-Expansion
Published 2025-01-01“…Notably, UBICU was shown to favor lung re-expansion more effectively than the traditional TriFlo mechanical system.…”
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Recruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial
Published 2025-01-01“…Wilcoxon tests found significant differences between lockdown (pilot 1 and pilot 2) and postlockdown (minitrials 1-6) on costs incurred per link click (lockdown: median Aus $0.35 [US $0.22], IQR Aus $0.27-$0.47 [US $0.17-$0.29]; postlockdown: median Aus $1.00 [US $0.62], IQR Aus $0.70-$1.47 [US $0.44-$0.92]; W=9087; P<.001) and the amount spent per hour to reach the target sample size (lockdown: median Aus $4.75 [US $2.95], IQR Aus $1.94-6.34 [US $1.22-$3.97]; postlockdown: median Aus $13.29 [US $8.26], IQR Aus $4.70-25.31 [US $2.95-$15.87]; W=16044; P<.001). …”
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