Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients by Liu K, Yang L, Liu Y, Zhang Y, Zhu J, Zhang H, He Z

“…Multiple logistic regression analysis showed that SII (OR 1.051 95% CI (1.035– 1.066), P < 0.001), NLR (OR 1.077,95% CI (1.032– 1.123), P < 0.001) were significantly associated with stroke severity. …”
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Magnitude of female child sexual abuse in Ethiopia: A systematic review and meta-analysis by Gemeda Wakgari Kitil, Dagne Deresa Dinagde, Fikadu Wake Butta, Melese Adugna Tola, Gizu Tola Feyisa, Shambel Negesse Marami, Wakuma Wakene Jifar, Geleta Nenko Dube, Adamu Ambachew Shibabaw, Chernet Desalegn Gebeyehu, Alex Ayenew Chereka

“…The pooled prevalence of child sexual abuse among female students was 36.83 % [95 % CI: 24.35–49.32]. This meta-analysis identified several factors significantly associated with child sexual abuse: children living alone (OR = 4.45, 95 % CI: 2.65–7.46), living with friends (OR = 3.49, 95 % CI: 2.35–5.18), alcohol consumption (OR = 2.72, 95 % CI: 1.70–4.35), cigarette smoking (OR = 3.83, 95 % CI: 1.66–8.83), parental conflicts (OR = 2.50, 95 % CI: 1.43–4.36), lack of open discussion about reproductive health (OR = 3.44, 95 % CI: 1.84–6.42), and family control practices (OR = 1.92, 95 % CI: 1.16–3.17). …”
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï... by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

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On-Demand Gait-Synchronous Electrical Cueing in Parkinson&#x0027;s Disease Using Machine Learning and Edge Computing: A Pilot Study by Ardit Dvorani, Constantin Wiesener, Christina Salchow-Hommen, Magdalena Jochner, Lotta Spieker, Matej Skrobot, Hanno Voigt, Andrea Kuhn, Nikolaus Wenger, Thomas Schauer

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Factors influencing repeat blood donor lapsing in Guangzhou: based on the zero-inflated poisson regression model by KE Rongrong, XIE Guiyun, ZHENG Xiaoxiao, XU Yingying, HONG Xiaochun, LI Shijie, DENG Yongshi, SHEN Jinyu, CHEN Jinyan, OUYANG Jian

“…[Results] The zero-inflated part of ZIP showed that the risk of lapsing of male blood donors was 2.24 times that of female blood donors (OR 95% CI:1.864-2.696, P<0.001); the risk of lapsing of the 35-44 age group and over 45 age group was respectively 40% (OR 95% CI:0.455-0.790, P<0.001) and 61%(OR 95% CI:0.268-0.578, P<0.001) lower than that of the under 25 age group; the risk of lapsing for those who have donated blood twice and ≥3 times was respectively 50% (OR 95% CI:0.405-0.609, P<0.001) and 81% (OR 95% CI:0.154-0.225, P<0.001) lower than that of first-time donors; the risk of lapsing of those with junior high or high school education was 1.2 times that of those with a college degree or higher (OR 95% CI:1.033-1.384, P<0.05); the risk of lapsing for the divorced group was 2.02 times that of the married group (OR 95% CI:1.445-2.820, P<0.001); the risk of lapsing for those with an income (Yuan) of 10 000 to 50 000, 50 000 to 100 000 and more than 100 000 was respectively 0.67 (OR 95% CI:0.552-0.818, P<0.001), 0.72 (OR 95% CI:0.591-0.884, P=0.002) and 0.67 (OR 95% CI:0.535-0.834, P<0.001) times that of those with an income (Yuan) of less than 10 000. …”
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Mendelian randomization analysis of plasma proteins reveals potential novel tumor markers for gastric cancer by Wenhai Fan, Zhenjiang Wu, Shenghao Xu, Zhiheng Liu, Yiming Huang, Pan Wang

“…Specifically, CHST15 (OR = 0.7553, 95% CI = 0.6346 − 0.8988), L1CAM (OR = 0.7230, 95% CI = 0.5876 − 0.8896), FTMT (OR = 0.8246, 95% CI = 0.7241 − 0.9391), and PMM2 (OR = 0.5767, 95% CI = 0.3943 − 0.8433) were negatively correlated with GASTRIC CANCER, whereas ABO (OR = 1.1868, 95% CI = 1.0638 − 1.3240), FAM3D (OR = 1.2109, 95% CI = 1.0850 − 1.3515), FAM3B (OR = 1.2988, 95% CI = 1.0953 − 1.5402), ADH7 (OR = 1.3568, 95% CI = 1.1044 − 1.6670), MAP1LC3A (OR = 1.3704, 95% CI = 1.1194 − 1.6778), PGLYRP1 (OR = 1.4071, 95% CI = 1.1235 − 1.7623), PDE5A (OR = 1.7446, 95% CI = 1.2693 − 2.3978), GLUL (OR = 3.1203, 95% CI = 1.5017 − 6.4839), NFE2L1 (OR = 3.1759, 95% CI = 1.6163 − 6.2402), and MAFG (OR = 3.1945, 95% CI = 1.5329 − 6.6575) were positively correlated. …”
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Impact of the Smarter Safer Homes Solution on Quality of Life and Health Outcomes in Older People Living in Their Own Homes: Randomized Controlled Trial by Wei Lu, David Silvera-Tawil, Hwan-Jin Yoon, Liesel Higgins, Qing Zhang, Mohanraj Karunanithi, Julia Bomke, Joshua Byrnes, Jennifer Hewitt, Vanessa Smallbon, Jill Freyne, Deepa Prabhu, Marlien Varnfield

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Skin microbiota: pathogenic roles and implications in atopic dermatitis by Cong Huang, Cong Huang, Fan Zhuo, Fan Zhuo, Yang Guo, Yang Guo, Yang Guo, Siyu Wang, Siyu Wang, Siyu Wang, Siyu Wang, Kaoyuan Zhang, Kaoyuan Zhang, Xiahong Li, Xiahong Li, Wenkui Dai, Xia Dou, Xia Dou, Bo Yu, Bo Yu

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Anemia, Hyperglycemia, and Reduced Left Ventricular Ejection Fraction Improve the GRACE Score&rsquo;s Predictability for In-hospital Mortality in Acute Coronary Syndrome; Single-Ce... by Turu' Allo IJ, Pramudyo M, Akbar MR

“…Combining these variables yielded an NRI of 0.075 (p = 0.070) and an IDI of 0.035 (p = 0.029).Conclusion: Incorporating anemia, hyperglycemia, and reduced LVEF into the GRACE score improves its predictive capacity for in-hospital mortality in ACS patients. …”
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A Proposed mHealth Intervention to Address Patient Barriers to Colposcopy Attendance: Qualitative Interview Study of Clinic Staff and Patient Perspectives by Jennifer R Hemler, Rachel B Wagner, Brittany Sullivan, Myneka Macenat, Erin K Tagai, Jazmarie L Vega, Enrique Hernandez, Suzanne M Miller, Kuang-Yi Wen, Charletta A Ayers, Mark H Einstein, Shawna V Hudson, Racquel E Kohler

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Time trends in malaria incidence from 1992 to 2021 in high-risk regions: An age‑period‑cohort analysis based on the Global Burden of Disease study 2021 by Yu Cao, Hao Wu, Yongping Zhang, Xueyi Wu, Jingjing Li, Hanwu Chen, Wei Gao

“…Results: In 2021, the global age-standardized incidence rate of malaria declined to 3485.3 per 100,000 (95% uncertainty interval [UI]: 2804.5-4435.7), a 5.24% decrease since 1992. Sub-Saharan Africa has the highest age-standardized rate at 20,225.9 per 100,000 (95% UI: 16,033.5-25,862.6), accounting for 92% of all new cases globally. …”
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Distribution of sasX, mupA, and qacA/B genes and determination of genetic relatedness of epidemic methicillin-resistant Staphylococcus aureus strains associated with bloodstream in... by Rui Zhao, Bingyu Du, Lingling Hu, Chenxi Li, Fen Xue, Xing Wang, Changhong Jiang, Jinghua Wang, Yanfeng Zhao

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The Association Between Mitral Regurgitation and Long-Term Outcomes in Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention: A Retrospective Large Sample Cohor... by Yan N, Wu P, Zhu B, Ma A, Wang X, Hai X, Ma X, Jiang H, Yang S

“…Cox regression models were employed to analyze the association between MR and 3-year clinical outcomes after adjusting for various confounding factors.Results: Among the 6940 patients, 2871 (41.35%) exhibited no MR, 3681 (53.04%) had mild MR, and 388 (5.59%) had moderate/severe MR. …”
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Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis by Litong Ran, Xiufei Liu, Yongfeng Tian, Jiaran Zhu, Zhengyuan Gong, Qiao Qiao, Xin Jiang, Yuren Wang, Guojun Yang, Hongting Zheng, Yi Zheng, Hua Qu

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Comparative efficacy of repurposed drugs lopinavir-ritonavir and darunavir-ritonavir in hospitalised COVID-19 patients: insights from a tertiary centre cohort by Dóra Paróczai, Dóra Paróczai, András Bikov, András Bikov, Andreea Blidaru, Emanuel Bobu, Ana Lascu, Ana Lascu, Cristian Ion Mot, Cristian Ion Mot, Stefan Mihaicuta, Stefan Mihaicuta, Stefan Frent, Stefan Frent

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Hospitalizations, emergency medical care utilization, and contacts with the regional on-call medical services among nursing home residents in Germany: a cross-sectional study in 44... by Paula Lienesch, Heinz Rothgang, Ansgar Gerhardus, Karin Wolf-Ostermann, Falk Hoffmann, Jonas Czwikla

“…Emergency medical care utilization was positively associated with age group 85 + vs. 60–74 years (2.58 [1.14–5.84]) and long-term care grades 3 and 4/5 vs. 1/2 (2.65 [1.07–6.55], 6.31 [2.60–15.35]); negatively associated with 5 + vs. 1- < 3 years of residence (0.46 [0.24–0.86]); and not associated with sex, the number of Elixhauser diseases, and nutritional status. …”
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Le stress thermique environnemental dans l’espèce bovine : 1. Caractéristiques générales et méthodes d’évaluation by Christian Hanzen, Pauline Delhez, Emilie Knapp, Jean-Luc Hornick, Djalel Eddine Gherissi

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Assessment of clinical prognosis in autoimmune encephalitis: Girona score by Gary Álvarez Bravo, Giuseppe Guglielmini, Ana Quiroga Varela, Almudena Boix Lago, Ariadna Gifreu Fraixinó, Daniele Urso, Daniele Urso, Daniele Urso, Daniele Urso, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Lluís Ramió-Torrentà

“…We found that the third group had a higher risk of disability compared with the first group (p = 0.035). We identified that the mean initial score was significantly higher in the group of patients who had higher mRS at 3 months compared to that in the group of patients who had a mild to moderate disability level (mRS ≤ 2) at 3 months (p = 0.023). …”
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Efficacy analysis of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer: a retrospective study by Zhijie Gong, Zhijie Gong, Liping Zhou, Yinghao He, Yinghao He, Jun Zhou, Yanjie Deng, Zudong Huang, WeiWei Wang, Qiangbang Yang, Jian Pan, Yingze Li, Xiaolu Yuan, Minghui Ma

“…Further analysis indicated that neither the number of P-HIPEC sessions had a significant impact on OS (p = 0.388) or DFS (p = 0.735), nor did the timing of P-HIPEC initiation affect OS (p = 0.620) or DFS (p = 0.488). …”
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Longitudinal Utilization of Invasive Pain Treatment Procedures Among Veterans with Chronic Pain Following Use of Whole Health Services and Complementary and Integrative Health Ther... by Zeliadt SB, DeFaccio R, Carey EP, Etingen B, Rosser EW, Suri P, Chen JA, Bokhour BG, Coggeshall S

“…School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA; 6Seattle Epidemiologic Research and Information Center (ERIC), VA Puget Sound Healthcare System, Seattle, WA, USA; 7Center for Healthcare Organization and Implementation Research, VA Bedford Healthcare System, Bedford, MA, USA; 8Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USACorrespondence: Steven B Zeliadt, VA Center of Innovation (COIN) for Veteran-Centered and Value-Driven Care, VA Puget Sound Healthcare System, 1660 South Columbian Way, S-15, Seattle, WA, 98108, USA, Tel +1 206 277-4175, Fax +1 206 764-2935, Email steven.zeliadt@va.govObjective: To assess whether Whole Health, a system of care that emphasizes non-pharmacological approaches for chronic pain management, is associated with changes in downstream utilization of invasive pain treatment procedures.Methods: Longitudinal retrospective cohort analysis of VHA administrative data. …”
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