Development of the cultural tailoring score (CTS): a scoring instrument to assess cultural tailoring of health messaging by Claudia Parvanta, Kayleigh Murray, Samantha Boddupalli, Natalie Erasme, Rheese McNab, Vijay Prajapati, Arabel Severe, Aura Reyes, Richard Harner, Rhonda Holliday

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The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

“…Results A total of 5,046 adults (representing 42,753,806 individuals, weighted mean age 61.08 years [SE: 0.24]; 49.35% female) were analyzed. The TyG index was significantly associated with all-cause and CVD mortality, and these associations were modified by the use of antidiabetic and hypolipidemic agents (p < 0.01). …”
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The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial by Xiaohong Chen, Bingqian Liu, Xiaoling Liang, Jiaqing Li, Tao Li, Yonghao Li, Xiling Yu, Cancan Lyu, Xiujuan Zhao, Silvia Tanumiharjo, Chenjin Jin, Lin Lu

“…Participants in the K group had a statistically significantly lower intraoperative NRS score (median 1.0 versus 3.0, P=0.003), lower postoperative NRS score (median 0 versus 1.0, P=0.035), fewer proportion of rescue analgesic requirement (10% versus 34.5%, P=0.023), and lower incidence of postoperative nausea and vomiting (13.3% versus 41.4%, P=0.015) compared to the C group. …”
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Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials by Sathish Muthu, Sathish Muthu, Sathish Muthu, Vibhu Krishnan Viswanathan, Vibhu Krishnan Viswanathan, Prakash Gangadaran, Prakash Gangadaran, Prakash Gangadaran

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Ｒｏｕｘ－ｅｎ－Ｙ胃旁路术对２型糖尿病大鼠肾脏氧化应激的影响

“…【结果】 术后８周ＤＯ组ＦＢＧ由术前的（１２．４８ ± １．３７）ｍｍｏｌ／Ｌ降至（ ５．４５ ± ０．７１）ｍｍｏｌ／Ｌ，术后８周空腹血清ＧＬＰ－１ 由术前（８．１２ ± １．５４） ｐｍｏｌ／Ｌ 升至（２２．３５ ± ０．７９）ｐｍｏｌ／Ｌ，余各组无明显变化；ＤＣ组和ＤＳＯ组肾组织ＭＤＡ水平、尿微量白蛋白、尿８－ＯＨｄＧ量、肾组织ＲＡＧＥ表达，血清ＡＧＥ水平和肾质量指数明显高于ＤＯ组和ＮＣ组（Ｐ＜ ０．０５）；抗氧化酶ＧＳＨ－ＰＸ、ＴＳＯＤ 、ＣＡＴ活性在ＤＣ组和ＤＳＯ组明显低于ＤＯ组和ＮＣ组（Ｐ ＜ ０．０５）； ＰＡＳ染色显示ＤＣ组和ＤＳＯ组肾小球细胞外基质积聚，ＤＯ组和ＮＣ组无明显变化。…”
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Cytotoxic and cytostatic activity of five new imidazotetrazine derivatives on breast cancer cell cultures MDAMB231, BT474, and MCF-7 by Ahmed Hamid Al-Humairi, Svetlana E. Sitnikova, Valery V Novochadov

“…Thus, 3-Cyclohexyl-4-oxoimidazo[5,1-d]-[1,2,3,5]tetrazine-8-N-piperidinyl-carboxamide (imidazotetrazine 4) is an unconditional leader in the tested series of new azoloazine derivatives and we recommend it for further preclinical trials.…”
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T-bet基因转染对哮喘小鼠脾脏Th1/Th2平衡的影响

“…【目的】 观察气道内T-bet基因转染对哮喘小鼠脾脏淋巴细胞Th1/Th2平衡65380;T-bet及GATA-3 mRNA表达的影响65377; 【方法】 将C57BL/6小鼠32只随机分为4组,每组8只,分别为正常对照组(A组)65380;哮喘模型组(B组)65380;空质粒干预组(C组) 和T-bet质粒干预组(D组)65377;卵白蛋白(OVA) 抗原溶液腹腔注射致敏,滴鼻造模65377;空质粒组和T-bet质粒干预组OVA激发24 h前,分别经鼻滴入50 μg空质粒65380;重组T-bet质粒,对照组用生理盐水代替OVA65377;最后一次滴鼻激发48 h后处死小鼠,流式细胞仪检测各组实验小鼠的脾脏淋巴细胞的Th1/Th2, RT-PCR检测小鼠脾脏淋巴细胞的T-bet及GATA-3mRNA表达65377; 【结果】 哮喘小鼠气道转染pcDNA3-T-bet质粒后:①流式细胞仪检测发现,脾脏Th1百分率较哮喘模型组显著升高[(2.29 ± 1.55)% vs. (1.93 ± 1.14)%,P﹤0.05],Th2百分率显著降低[(0.93 ± 0.64)% vs. (1.63 ± 0.59)%];②RT-PCR检测发现脾脏淋巴细胞转录因子T-bet mRNA表达水平显著增加(0.53 ± 0.027 vs. 0.28 ± 0.035,P﹤0.05), GATA-3 mRNA表达水平显著降低(0.24 ± 0.022 vs. 0.58 ± 0.038,P﹤0.05)65377;而pcDNA3空质粒干预后与哮喘模型组比较无显著差异65377;【结论】 气道内转导pcDNA3-T-bet质粒后,可显著上调哮喘小鼠体内T-betmRNA表达,下调GATA-3 mRNA表达,有效改善哮喘小鼠体内Th1/Th2比例失衡,从而抑制哮喘小鼠的气道炎症,为哮喘的T-bet基因治疗提供依据65377;…”
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Neonatal mortality of live births with congenital diaphragmatic hernia in São Paulo State, Brazil: Failure of care? by Ana Sílvia Scavacini Marinonio, Milton Harumi Miyoshi, Daniela Testoni Costa Nobre, Adriana Sanudo, Kelsy Catherina Nema Areco, Mandira Daripa Kawakami, Rita de Cássia Xavier Balda, Tulio Konstantyner, Carina Nunes Vieira e Oliveira, Paulo Bandiera-Paiva, Rosa Maria Vieira de Freitas, Monica La Porte Teixeira, Bernadette Cunha Waldvogel, Carlos Roberto Veiga Kiffer, Maria Fernanda Branco de Almeida, Ruth Guinsburg

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Sol–gel synthesis of silicon oxide (SiO2) nanoparticles: exploring gas sensing and photocatalytic applications by Laxmi D. Sonawane, Abhinay S. Mandawade, Anil B. Gite, Sarika D. Shinde, Ganesh E. Patil, Latesh K. Nikam, Vishal H. Goswami, Ramesh B. Bhise, Pradip B. Sarawade, Mahendra S. Shinde

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Subproductos de cacao (Theobroma cacao) en la alimentación animal: ¿Una alternativa viable y sostenible? by Ramiro Juan Vega-González, Daniel Castro-Salinas, Fredy Marcial Pajuelo-Risco, César Eduardo Honorio-Javes, Juan Ernesto Hernandez-Valdez

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Predicting Damage in Notched Functionally Graded Materials Plates through extended Finite Element Method based on computational simulations by Hakim Siguerdjidjene, Amin Houari, Kouider Madani, Salah Amroune, Mohamed Mokhtari, Barhm Mohamad, Chellil Ahmed, Abdelkrim Merah, Raul Campilho

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The role of physical education in shaping soft skills and self-regulation in senior students: an economic perspective by Artem Synytsia, Ihor Koval, Serhii Kuzhelnyi, Serhii Dzhemesiuk, Serhii Kudin, Andrii Kuzhelnyi, Tatiana Zhlobo, Lidiia Zhula

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Pediatric Intracochlear Schwannoma: Case Series and Review of the Literature by Enrico Liaci, Maurizio Negri, Francesco Maccarrone, Silvia Piccinini, Enrico Pasanisi, Andrea Bacciu, Filippo Di Lella

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Insights into the contribution of multiple factors on Ixodes ricinus abundance across Europe spanning 20 years using different machine learning algorithms by Samantha Lansdell, Abin Zorto, Misaki Seto, Edessa Negera, Saeed Sharif, Sally Cutler

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Phenotypic age mediates the associations between platelet-to-lymphocyte ratio and all-cause and cause-specific mortality: A prospective cohort study by Xiangjun Li, Jia Wang, Mengqi Zhang, Yujing Li, Xiaoxuan Li, Jiaqi Zhang, Lihua Zhang, Yixuan Zhang, Zhenkang Qiu

“…Moreover, mediation analysis revealed that PhenoAge partially mediated 45.33 %, 44.26 %, and 15.35 % of the associations of PLR with all-cause, CVD, and respiratory disease mortality, respectively. …”
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Abortion Rate Following Chorionic Villous Sampling and Amniocentesis in Twin Pregnancies by Fatemeh Golshahi, Fatemeh Rahimi-Sharbaf, Mahbobeh Shirazi, Sara Saeedi, Athar Abdolrazagh Nejad, Sahar Garfami, Nafise Saedi, Jafar Golshahi, Zeynab Amiriarya, Narjes Tavakolikia, Behrokh Sahebdel

“…Results: The mean age of women was 33.5 ± 6.5 years. About 90 % of pregnant women underwent amniocentesis and the others underwent CVS. …”
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Health IT Implementation and the Impact of the COVID-19 Pandemic on Clinician-IT Dynamics: Qualitative Study by Adeola Bamgboje-Ayodele, Adrian Boscolo, Mitchell Burger, Owen Hutchings, Miranda Shaw, Tim Shaw, Amina Tariq, Sundresan Naicker, Steven McPhail, Melissa Baysari

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Transmisión de la COVID-19 en el Municipio Abreus, entre las semanas 29 y 41 del año 2021 by Jorge Enrique Rodríguez León, Esther Yarinely Hernández Diéguez, Anay de la Caridad Núñez Herrera, Niuvys Valera Rodríguez, Julian Sobral Rey, Regla Reinaldo Conyedo

“…Tendencia al incremento del reporte de casos y de la velocidad de transmisión desde la semana estadística 29 a la 35 (385 a 3421 casos). El pico máximo se observó en la semana estadística 33, con disminución a partir de dicha semana; además, hubo una dispersión en todos los consejos populares, con mayor concentración en los consejos populares Abreus (1035) y Horquita (725). …”
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Les vues glaciaires de Jean-Antoine Linck – un jalon de l’histoire des glaciers du Mont Blanc du xviiie au xixe siècle by Samuel U. Nussbaumer, Heinz J. Zumbühl

“…Par exemple, des documents historiques ont été appliqués pour reconstituer d’anciennes étendues des glaciers sur différents sites, notamment dans la région du Mont-Blanc, qui sont très bien documentés et devenus populaires parmi les artistes, les scientifiques et les voyageurs depuis le milieu du xviiie siècle. …”
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A review of the types of diets used in Crohn’s disease: the support system for pharmacological treatment by Joanna Śnieżna, Wojciech Wojciech Florczak, Jakub Dziewic, Karol Dzwonnik, Urszula Zelik, Gabriela Trestka, Wiktoria Domino, Kamila Stępień, Jagienka Włodyka, Sabina Adamczyk, Maria Przygoda

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