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4701
Stage-specific function of sphingolipid synthases in African trypanosomes
Published 2025-02-01“…To investigate individual TbSLS functions, separate HA-tagged genes, recoded to be RNAi-resistant (RNAiR), were engineered to replace a single allele of the entire TbSLS locus within parental BSF and PCF RNAi cell lines. …”
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4702
Intravitreal dexamethasone implant (Ozurdex®) findings over time: ultrasound and ultra-widefield fundus photography
Published 2025-01-01“…Methods In this study, we included patients aged ≥ 18 years with one or two eyes who had an indication for Ozurdex® implants. …”
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4703
Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins
Published 2025-01-01“…Here, we investigated the interaction of Physcomitrella FtsZ2-1 with FtsZ1 isoforms via co-immunoprecipitation and mass spectrometry, and found protein-protein interaction in vivo. We tagged FtsZ1-2 and FtsZ2-1 with different fluorophores and expressed both in E. coli, which led to the formation of defined structures within the cells and to an influence on bacterial cell division and morphology. …”
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4704
Multidimensional Plasma Lipids Affect Preeclampsia/Eclampsia: A Mendelian Randomization Study
Published 2025-01-01“…The study identified 17 lipid species from a total of 179 lipid species associated with susceptibility to preeclampsia/eclampsia. Notably, ten species, including six triacylglycerols (TAGs) (50:1, 48:1, 56:4, 49:2, 48:2, 54:3), a diacylglycerol (DAG) (16:1_18:1), and three sphingomyelins (SMs) (d36:1, d34:1, d38:1), were found to increase the risk of preeclampsia/eclampsia. …”
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4705
Improving of Surface Quality of Metal Reflector Mirrors Machined by Single Point Diamond Turning
Published 2021-06-01“…The analysis of the surface structure of the AMg2 alloy substrates was carried out by scanning electron microscopy / electron microprobe. …”
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4706
Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition
Published 2024-12-01“…NMDA (30 μM) induced stable inward cation currents, significantly inhibited by Ang IV (1 nM–1 µM) in a subset of pyramidal neurons. …”
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4707
Antibacterial activity, quality and stability study of creams with new potential silver(I) complexes and in vivo case report
Published 2023-06-01“…The aim of this study was to evaluate the antibacterial activity, quality and stability of creams (at 1 % concentration) prepared with synthesized silver(I) complexes: [Ag(Nam)2]NO3·H2O ( AgNam), [Ag2(HGly)2]n(NO3)2n (AgGly) (Nam – nicotin-amide, Gly – glycine) and silver(I) sulfadiazine (AgSD), which is commercially available. …”
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4708
Fitobentos in kakovost vode v mrtvicah reke Mure
Published 2010-12-01“…V mrtvici Zaton I smo skupno identificirali 37, v mrtvici Zaton II 75 in v mrtvici Mali Bakovci 107 taksonov alg. V izbranih mrtvicah reke Mure smo skupno ugotovili 25 taksonov, ki do sedaj še niso bili znani na območju Slovenije. 19 za Slovenijo novih taksonov pripada razredu kremenastih alg, Borzia curta in Woronichinia robusta razredu cianobakterij, Bumilleria klebsiana in B. spirotaenia razredu Xanthophyceae ter Characium ensiforme in Microspora abbreviata razredu Chlorophycea. …”
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4709
Therapeutic role of miR-26a on cardiorenal injury in a mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway
Published 2025-01-01“…We generated an microRNA (miR)-26a knockout (KO) mouse model to investigate the role of miR-26a in angiotensin (Ang)-II-induced cardiac and renal injury. We performed Ang-II modeling in wild type (WT) mice and miR-26a KO mice, with six mice in each group. …”
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4710
Endothelin but Not Angiotensin II May Mediate Hypertension-Induced Coronary Vascular Calcification in Chronic Kidney Disease
Published 2011-01-01“…To understand the relationship between putative neurohormonal factors operative in hypertension and coronary artery calcification (CAC), the relevant cellular actions of angiotensin (Ang II) and endothelin-1 (ET-1) are reviewed. There is compelling evidence to implicate ET-1 in CAC. …”
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4711
Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells
Published 2015-01-01“…Addition of Ang II to VEGF-A and IL-6 or TNFα was sufficient to rescue the EC phenotype. …”
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4712
Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo
Published 2019-01-01“…Our results showed that Ang-(1-7) and alamandine, through Mas and MrgD receptors, respectively, do not affect M0 macrophages but reduce the proinflammatory TNF-α, CCL2, and IL-1β transcript expression levels in LPS+IFN-γ-stimulated macrophages. …”
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4713
Life history, reproductive, and demographic parameters for bottlenose dolphins (Tursiops truncatus) in Sarasota Bay, Florida
Published 2025-02-01“…Detailed histories have been collected for resident individuals through integrated observations, systematic photographic identification surveys, tagging and tracking, catch-and-release health assessments, remote biopsy sampling, and stranding response. …”
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4714
Measurement of CP violation in B0 → D+D − and B s 0 $$ {\textrm{B}}_{\textrm{s}}^0 $$ → D s + D s − $$ {\textrm{D}}_{\textrm{s}}^{+}{\textrm{D}}_{\textrm{s}}^{-} $$ decays
Published 2025-01-01“…Abstract A time-dependent, flavour-tagged measurement of CP violation is performed with B 0 → D + D − and B s 0 $$ {B}_s^0 $$ → D s + D s − $$ {D}_s^{+}{D}_s^{-} $$ decays, using data collected by the LHCb detector in proton-proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 6 fb −1. …”
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4715
The Angiotensin II Type 2 Receptor in Brain Functions: An Update
Published 2012-01-01“…Angiotensin II (Ang II) is the main active product of the renin-angiotensin system (RAS), mediating its action via two major receptors, namely, the Ang II type 1 (AT1) receptor and the type 2 (AT2) receptor. …”
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4716
Physicochemical Characteristics of Chitosan–Alginate Scaffold Containing Atorvastatin
Published 2023-01-01“…For this purpose, a CS/ALG hydrogel crosslinked with TPP was developed. …”
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4717
Tyrosine Kinase-2, Angiopoietin-2, and Thrombomodulin Axes in the Late-Onset Fetal Growth Restriction: A Prospective Cohort Study
Published 2024-12-01“…However, the sensitivity and specificity of these proteins within the Tie-2, Ang-2, and TM axes were 51%, 56%, 51%, and 45%, 52%, and 50%, respectively. …”
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4718
Recombinant Production of Bovine α<sub>S1</sub>-Casein in Genome-Reduced <i>Bacillus subtilis</i> Strain IIG-Bs-20-5-1
Published 2025-01-01“…Subsequent high cell-density fed-batch bioreactor cultivations using strain IIG-Bs-20-5-1 resulted in a volumetric casein titer of 56.9 mg/L and a yield of 1.6 mg<sub>casein</sub>/g<sub>CDW</sub> after reducing the <i>B. subtilis</i> protein content. …”
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4719
Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats
Published 2025-02-01“…The renin angiotensin aldosterone system (RAAS), including the levels of renin, angiotensin I (Ang I), angiotensin II (Ang II), aldosterone (ALD), angiotensin-converting enzyme (ACE) and other molecules related to blood pressure, such as NO, prostacyclin (PGI2), endothelin-1 (ET1), and thromboxane A2 (TXA2), were measured in rat blood. …”
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4720
Rumen DNA virome and its relationship with feed efficiency in dairy cows
Published 2025-01-01“…Conclusions This study constructed a comprehensive rumen DNA virome profile for Holstein dairy cows, elucidating the structural and functional complexity of rumen viruses, the roles of AMGs, and vOTU-hMAG linkages. The integration of these data offers novel insights into the mechanisms by which rumen viruses may regulate nutrient utilization, potentially influencing FE in dairy cows. …”
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