The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming by Bharathi Suresh, Junwon Lee, Kye-Seong Kim, Suresh Ramakrishna

“…Ubiquitination and deubiquitination must occur in a timely and well-coordinated manner to regulate the protein turnover of several stemness related proteins, resulting in optimal embryonic stem cell maintenance and differentiation. There are two switches: an E3 ubiquitin ligase enzyme that tags ubiquitin molecules to the target proteins for proteolysis and a second enzyme, the deubiquitinating enzyme (DUBs), that performs the opposite action, thereby preventing proteolysis. …”
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Quantitative Ecological Study of Pilan Forest as a Baseline for Development of Gianyar Botanic Garden by Farid Kuswantoro, I Nyoman Lugrayasa, Wawan Sujarwo

“…The study was conducted using the quadrat plot (PU) method, with a plot measuring 20 m x 20 m for observation and tagging of all trees and saplings, as well as 2 mx2 m for observation of the understorey level. …”
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Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons by Shun Hiramatsu, Kokoro Saito, Shu Kondo, Hidetaka Katow, Nobuhiro Yamagata, Chun-Fang Wu, Hiromu Tanimoto

“…Our results highlight the significance of the co-expression of the two opposing dopamine receptors in the spatial and conditional regulation of dopamine responses in neurons.…”
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Analysis of Long-Range Transport of Carbon Dioxide and Its High Concentration Events over East Asian Region Using GOSAT Data and GEOS-Chem Modeling by Seung-Yeon Kim, Sang-Deok Lee, Jae-Bum Lee, Deok-Rae Kim, Jin-Seok Han, Kwang-Ho Choi, Chang-Keun Song

“…We can find out with GEOS-Chem tagging simulation that more than 45% of the elevated CO2 concentration over central/eastern China, Korea, and Japan on high concentration days can be explained by emission sources of East Asia mainland.…”
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Transcriptome of the Deep-Sea Black Scabbardfish, Aphanopus carbo (Perciformes: Trichiuridae): Tissue-Specific Expression Patterns and Candidate Genes Associated to Depth Adaptatio... by Sergio Stefanni, Raul Bettencourt, Miguel Pinheiro, Gianluca De Moro, Lucia Bongiorni, Alberto Pallavicini

“…A selection of putative genes was standardized to evaluate the correlation between number of contigs and their normalized expression, as determined by qPCR amplification. The screening of the libraries contributed to the identification of new EST simple-sequence repeats (SSRs) and to the design of primer pairs suitable for population genetic studies as well as for tagging and mapping of genes. …”
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Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice by Wesam E. Gawad, Yosra I. Nagy, Tamer M. Samir, Ahmed Mohamed Ibrahim Mansour, Omneya M. Helmy

“…Proteins were cloned, purified as His-tagged proteins, and loaded onto C:P NPs. Vaccinated mice had significantly higher systemic IgG and mucosal IgA antibody responses and induced IL-6 and IL-17A. 6x-His-LY-CS:P NPs and 6x-His-KT-CS:P NPs vaccines induced TNF-α. …”
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Acylcarnitine Profiles in Plasma and Tissues of Hyperglycemic NZO Mice Correlate with Metabolite Changes of Human Diabetes by Anna Weiser, Pieter Giesbertz, Hannelore Daniel, Britta Spanier

“…Concentrations of insulin, blood glucose, NEFAs, and triacylglycerols (TAGs) further supported the hypothesis of high BCAA-derived ACs being able to mirror the onset of diabetic traits in male individuals. …”
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Real-Time G-Protein-Coupled Receptor Imaging to Understand and Quantify Receptor Dynamics by María S. Aymerich, J. López-Azcárate, J. Bonaventura, G. Navarro, D. Fernández-Suárez, V. Casadó, F. Mayor, C. Lluís, M. Valencia, J. Artieda, Rafael Franco

“…Understanding the trafficking of G-protein-coupled receptors (GPCRs) and their regulation by agonists and antagonists is fundamental to develop more effective drugs. …”
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Comparative use of different AI methods for the prediction of concrete compressive strength by Mouhamadou Amar

“…This study utilized RapidMiner® software to design models capable of analyzing various types of tagged data and performing machine learning predictions. …”
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Fast vocal-motor tracking of escaping prey in echolocating bats by Ilias Foskolos, Antoniya Hubancheva, Marie Rosenkjær Skalshøi, Kristian Beedholm, Peter Teglberg Madsen, Laura Stidsholt

“…With high-resolution biologging tags, we recorded bats hunting aerial prey in the wild and we also collected data from trained conspecifics in the laboratory facing simulated prey escapes of various speeds and distances. …”
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Mapping the “catscape” formed by a population of pet cats with outdoor access by Richard Bischof, Nina Rosita Hansen, Øyvind Skarsgard Nyheim, Astrid Kisen, Lillian Prestmoen, Torbjørn Haugaasen

“…Using a citizen science approach, we GPS-tagged 92 pet cats with outdoor access living in a residential area in southern Norway. …”
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Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease by Taylor R. Church, Seth S. Margolis, Seth S. Margolis

“…Previously, it was believed that proteolysis by the proteasome required tagging of protein targets with polyubiquitin chains, a pathway called the ubiquitin-proteasome system (UPS). …”
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Development of new SSR markers for homoeologous WFZP loci based on the study of structure and location of microsatellites in gene-rich regions of chromosomes 2AS , 2BS, 2DS by O. B. Dobrovolskaya, C. Pont, Yu. L. Orlov, J. Salse

“…The most common dinucleotide motifs were AG and GA/TC. They were distributed in noncoding regions of genes, transposable elements (TEs) and unannotated sequences. …”
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Deep Recurrent Model for Server Load and Performance Prediction in Data Center by Zheng Huang, Jiajun Peng, Huijuan Lian, Jie Guo, Weidong Qiu

“…Recurrent neural network (RNN) has been widely applied to many sequential tagging tasks such as natural language process (NLP) and time series analysis, and it has been proved that RNN works well in those areas. …”
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Effect of fattening length, sex and feather colour on growth and fattening performance in native turkish geese by Mustafa Saatçi, Cavit Arslan, Yücel Ünal, Muammer Tilki, Ali Rıza Aksoy

“…Birds divided into four groups according to their feather colour in each fattening (10 and 12 weeks) period. Birds with wing tags were individually weighed and all the birds were weighted weekly according to their groups.…”
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Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy by Constanza J. Cortes, Kefeng Qin, Eric M. Norstrom, William N. Green, Vytautas P. Bindokas, James A. Mastrianni

“…Time-lapse live cell imaging revealed early formation and uptake of GFP-tagged Mut-PrP aggregates into LysoTracker labeled vesicles. …”
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Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond by Aref Yarahmadi, Masoumeh Dorri Giv, Reza Hosseininejad, Azin Rezaie, Narges Mohammadi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Arastoo Farokhi

Subjects: “…traumatic brain injury (TBI)…”
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Establishment of a Mutant Library for Infection Cushion Development and Identification of a Key Regulatory Gene in <i>Botrytis cinerea</i> by Maoyao Tang, Kexin Wang, Pan Zhang, Jie Hou, Xiaoqian Yu, Hongfu Wang, Yangyizhou Wang, Guihua Li

“…In this study, we utilized a forward genetics approach to establish a large T-DNA tagged population of <i>B. cinerea</i>, which contained 14,000 transformants. …”
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CD40 Gene Polymorphisms Associated with Susceptibility and Coronary Artery Lesions of Kawasaki Disease in the Taiwanese Population by Ho-Chang Kuo, Mei-Chyn Chao, Yu-Wen Hsu, Ying-Chi Lin, Ying-Hsien Huang, Hong-Ren Yu, Ming-Feng Hou, Chi-Di Liang, Kuender D. Yang, Wei-Chiao Chang, Chih-Lu Wang

“…A total of 950 subjects (381 KD patients and 569 controls) were investigated to identify 2 tagging single-nucleotide polymorphisms (tSNPs) of CD40 (rs4810485 and rs1535045) by using the TaqMan allelic discrimination assay. …”
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Growth on Alpha-Ketoglutarate Increases Oxidative Stress Resistance in the Yeast Saccharomyces cerevisiae by Maria Bayliak, Nadia Burdyliuk, Volodymyr Lushchak

“…Alpha-ketoglutarate (AKG) is an important intermediate in cell metabolism, linking anabolic and catabolic processes. …”
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