Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis by Chuanxin Liu, Xiaobin Huang, Jiao Kong, Xuejiao Li, Yuming Wang, Fangfang Zhang, Jiajia Duan

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TESTING POTATO COLLECTION SAMPLES FOR THE PRESENCE OF GENES FOR RESISTANCE TO PHYTOPATHOGENS BY MEANS OF DNA MARKERS by A. B. Saynakova, M. S. Romanova, S. N. Krasnikov, O. V. Litvinchuk, Ya. I. Alekseev, A. V. Nikulin, E. V. Terentjeva

“…As a result, we identified marker NL25 (Sen1) in 19 samples; marker PVX (Rx) in 13 samples; marker RYSC3312 (Ryadg) in 10 samples; marker YES3-3A341 (Rysto) in 5 samples; markers TG 689141, 57R450, N195337 (H1) in 12 samples; marker Gro1-4-1602 (Gro1-4) in 6 samples; marker Gpa2-2452 (Gpa2) in 13 samples. …”
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ANGPTL4: A Predictive Marker for Diabetic Nephropathy by Eman Al Shawaf, Mohamed Abu-Farha, Sriraman Devarajan, Zahra Alsairafi, Irina Al-Khairi, Preethi Cherian, Hamad Ali, Aditi Mathur, Fahd Al-Mulla, Abdulnabi Al Attar, Jehad Abubaker

“…ANGPTL4 level was increased in people with DN (241.56±14.1 μg/ml) compared to the control group (178.43±24.09 μg/ml). …”
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Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids by Maria Aslam, Omer Riaz, Jawaria Aslam, Dost Muhammad Khan, Mustafa Hameed, Muhammad Suleman, Rizwan Shahid, Turke Althobaiti, Naeem Ramzan

“…The intricate landscape of lipid metabolism plays a crucial role in SIDS, with disruptions in key lipid components like Short Chain Fatty Acids (SCFA), alongside other lipids such as triglycerides (TG) and phospholipids (PL), being significant. In this context, SCFA are essential products of the fermentation process by gut microbiota, hold particular interest. …”
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Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study by Youli Tian, Jintong Li, Minggen Jin, YiHua Piao, Jisheng Sheng, Zhixiong Mei, Qingsong Cui, Lilin Li

“…Under the same analgesic regimen, the two groups received remimazolam and propofol for procedural sedation. …”
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Characterisation of cardiovascular disease (CVD) incidence and machine learning risk prediction in middle-aged and elderly populations: data from the China health and retirement lo... by Qing Huang, Zihao Jiang, Bo Shi, Jiaxu Meng, Li Shu, Fuyong Hu, Jing Mi

“…Shapley additive explanations (SHAP) analyses revealed the importance of key features, such as night sleep duration, TG levels, and waist circumference, in predicting outcomes, and highlighted the nonlinear relationships between these features and CVD risk. …”
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The effect of using Echinacea extract as an immune system stimulant and antioxidant on blood indicators, growth efficiency, and carcass characteristics in broiler chickens to produ... by Elwy A. Ashour, Ahmed K. Aldhalmi, Ismail E. Ismail, Mahmoud Kamal, Ahmed A. Elolimy, Ayman A. Swelum, Mohamed E. Abd El-Hack

“…Also, the control had higher TP, albumin, and globulin levels, while the EPE diet increased ALT and AST and decreased TC, TG, LDL, and VLDL levels. …”
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Prospective study of the association between chronotype and cardiometabolic risk among Chinese young adults by Tingting Li, Yang Xie, Shuman Tao, Liwei Zou, Yajuan Yang, Fangbiao Tao, Xiaoyan Wu

“…The cardiometabolic (CM)-risk score was the sum of standardized Z scores based on gender for the 5 indicators: waist circumference (WC), mean arterial pressure (MAP), triglyceride (TG), homeostasis model assessment for insulin resistance (HOMA-IR), and high-density lipoprotein cholesterol (HDL-C), where the HDL-C is multiplied by-1. …”
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The impact of dietary patterns on gut microbiota for the primary and secondary prevention of cardiovascular disease: a systematic review by Junwen Yu, Yue Wu, Zheng Zhu, Hongzhou Lu

“…Plant-rich diets showed a significant decrease in total cholesterol (TC) with a mean difference of -6.77 (95% CI, -12.36 to -2.58; I 2  = 84.7%), while restrictive diets showed a significant decrease in triglycerides (TG) of -22.12 (95% CI, -36.05 to -8.19; I 2  = 98.4%). …”
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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Glycolipid concentrations were measured using kits, and the expression of key genes involved in glucose metabolism was assessed via quantitative real-time PCR (qRT-PCR). The insulin tolerance test, performed by injecting 5 IU/kg body weight of insulin, demonstrated a rapid drop in blood glucose levels from 0 to 15 min, with a consistent reduction observed at 120 min (P < 0.01). …”
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Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…Methods A single-centre nonblinded RCT in 40 patients with chronic PFP (> 1 year) and tibial tubercle-trochlear groove (TT-TG) > 15 mm will be randomised to either TTT followed by PT or to PT alone in a 1:1 ratio in a concealed manner. …”
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Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

“…Our findings indicated that lower doses of HQ (12.5 and 25.0 mg/kg) led to lipid accumulation in the liver, accompanied by increased liver TG and serum TC. …”
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Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide pros... by Gaoshu Zheng, Jijie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jianghua Zhou

“…Further weighted quartiles and regression analyses indicated that triglyceride(TG) was a key variable for AIP in predicting CVD events in the CKM stages 0–3 population. …”
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Correlation of irisin with lipid profile in type 2 diabetes mellitus by Wahengbam Diana Devi, Oinam Prabita Devi, Ursula Khwairakpam, Takhelmayum Paras Singh

“…Results: Irisin was found to be lesser (P=0.00) in T2DM cases (14.5±8.6 ng/mL) as compared to controls (28.4±3.9 ng/mL). …”
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The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice by Shanshan Zhang, Xinle Xu, Xu Cao, Tingting Liu

“…In vivo experiment results in mice indicated that SDF has the best effect on hyperlipidemia mice than IDF and total dietary fiber (TDF). SDF showed that the total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) contents dropped by 28.33 %, 18.65 %, and 48.97 %, respectively, while high density lipoprotein cholesterol (HDL-C) content increased by 43.80 %. …”
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Comparison of various feed additives on nutrient digestibility, digestive enzyme activity, blood metabolite levels, and gut microbiota composition in japanese quail chicks by Hassan Saleh, Omid Jangjou, Mohammad Taher Mirakzehi, Seyedeh Hamideh Hosseni

“…However, no significant difference in lipase activity was observed among the various dietary supplements. The levels of LDL, TG, MDA, ALT, IgG, and IgM were influenced by the experimental treatments. …”
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Response of plant life forms and soil physical properties to near-natural restoration measures in alpine grassland, Tibetan plateau by Guoxing He, Guoxing He, Xiaoni Liu, Xiaoni Liu, Yali Li, Yali Li, Tong Ji, Tong Ji

“…IntroductionNear-natural restoration measures enhance the stability of plant life forms in degraded grasslands, facilitating the natural succession of plant communities.MethodsIn this study, we investigated the effects of three natural restoration measures on the alpine meadows of the northeastern Tibetan Plateau: banned grazing (BG), rest grazing (RG), traditional grazing (TG), and continuous grazing (CG). …”
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Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) by Weijia Cai, Xinping Li, Minglang Cai, Zhe Tang, Bo Zhu, Mengxi Yang, Yi Hu, Jihong Dai

“…At the same time, the pro-inflammatory factors inos, tgf-β, tnf-α and il-1β were significantly upregulated in these two groups (P < 0.05). …”
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Impacts of Thermal Activation on Physical Properties of Coal Gangue: Integration of Microstructural and Leaching Data by Wangtao Fan, Yuan Chen, Runxia Zhang, Xiaoguang Chen, Jin Li, Zhaolin Gu, Jianyun Wang

“…The Si and Al in 800 °C calcined coal gangue exhibited a high leaching ability in alkalinity solution; leachable Al reached 106.4 mg/kg, while leachable Si reached 86.1 mg/kg after 48 h of dynamic leaching.…”
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Effect of soluble dietary fiber extracted from Lentinula edodes (Berk.) Pegler on lipid metabolism and liver protection in mice on high-fat diet by Kangxiao Guo, Kangxiao Guo, Jing Liu, Zihan Yao, Zhoujin Tan, Tao Yang

“…The soluble dietary fiber of Lentinus edodes can effectively slow the weight growth due to high-fat diet, delay liver tissue lesions, reduce the levels of ALT, AST, ACP, LDL-C, TG, TV, FFA, SOD, GSH and MDA, and increase the levels of γ-GT, HDL-C and CAT in blood. …”
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