Sex Differences Associated with Primary Biliary Cirrhosis by Daniel S. Smyk, Eirini I. Rigopoulou, Albert Pares, Charalambos Billinis, Andrew K. Burroughs, Luigi Muratori, Pietro Invernizzi, Dimitrios P. Bogdanos

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Fusion-Learning-Based Optimization: A Modified Metaheuristic Method for Lightweight High-Performance Concrete Design by Ghodrat Rahchamani, Seyed Mojtaba Movahedifar, Amin Honarbakhsh

“…The SVR technique proposes an optimization method for finding the kernel radial basis function (RBF) parameters based on improving the innovative gunner algorithm (AIG). As a result of AIG's diverse solutions, local optima are effectively avoided. …”
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Gene Expression Profile in Delay Graft Function: Inflammatory Markers Are Associated with Recipient and Donor Risk Factors by Diego Guerrieri, Luis Re, Jorgelina Petroni, Nella Ambrosi, Roxana E. Pilotti, H. Eduardo Chuluyan, Domingo Casadei, Claudio Incardona

“…The most relevant genes fold changes observed was IFNA1, IL-10, IL-1F7, IL-1R1, HMOX-1, and TGF-β. The results were confirmed for IFNA1, IL-1R1, HMOX-1 and TGF-β. …”
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Integrating Metabolomics and Genomics to Uncover the Impact of Fermented Total Mixed Ration on Heifer Growth Performance Through Host-Dependent Metabolic Pathways by Zhenzhen Hu, Minyu Zuo, Shixuan Ding, Yifan Zhong, Mingyuan Xue, Huichao Zheng

“…Twenty-eight metabolites were significantly associated with ADG (R > 0.3, <i>p</i> < 0.05). Four of them were identified as biomarkers, primarily regulating energy metabolism and oxidative balance. …”
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Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…A total of 26 patients with AEG will be enrolled. The primary endpoint is the pathologic complete response (pCR) rate after perioperative neoadjuvant immunochemotherapy. …”
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Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2... by Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel

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Dietary tea tree (Melaleucae Aetheroleum) oil fortifies growth, biochemical, immune-antioxidant trait, gene function, tissue reaction, and Aeromonas sobria resistance in Nile tilapia (Oreochromis niloticus) by Mohamed Shaalan, Heba H. Mahboub, Ahmed Hosny Abdelgawad, Abdelwahab A. Abdelwarith, Elsayed M. Younis, Ahmed A. Elnegiry, Asmaa W. Basher, Walaa El-Houseiny, Sherif M. Shawky, Sahar H. Orabi, Simon J. Davies, Yasmina K. Mahmoud

“…Concurrently, fish that were fed a 2.0 mL TTO/kg diet exhibited a substantial upregulation of TNF-α, IL-1β, IL-10, TFG-β, IFN-γ and BCL-2 genes in the liver, while, caspase-3, and BAX were downregulated. …”
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Impairment of myocardial perfusion correlates with heart failure severity in patients with non‐compaction cardiomyopathy by Andraz Cerar, Martina Jaklic, Sabina Frljak, Gregor Poglajen, Gregor Zemljic, Barbara Guzic Salobir, Maja Dolenc Novak, Monika Stalc, Rok Zbacnik, Mirta Kozelj

“…. −14.5 ± 4.1%, P = 0.001), and higher NT‐proBNP levels (1691 ± 1883 pg/mL vs. 422 ± 877 pg/mL, P = 0.006). Overall, higher summed difference score was associated with lower LVEF (r = −0.48, P = 0.001), higher LVEDV (r = 0.39, P = 0.012), lower GLS (r = 0.352, P = 0.024), and higher levels of NT‐proBNP (r = 0.66, P < 0.001). …”
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Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis by Kaiwen Sheng, Jun Chen, Ruitang Xu, Haoqiang Sun, Ran Liu, Yongjie Wang, Wenwen Xu, Jiao Guo, Miao Zhang, Shuai Liu, Juan Lei, Yawen Sun, Yang Jia, Dianhao Guo

“…In conjunction, we integrated these data with 55 scRNA-seq datasets, ChIP-seq or CUT&Tag sequencing data, Hi-C sequencing data, bulk RNA-seq data, and bulk ATAC-seq data from ESCC cell lines to dissect the mechanisms underlying the heterogeneity of ESCC and tumor microenvironment (TME). …”
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Spatial-temporal baseline study of nutrients and trace elements characterization of a large tropical transition system in West Africa by Celso Paulo, João A. Carreiras, Susanne Tanner, Carmen Van-Dúnem dos Santos, Vanessa F. Fonseca, Bernardo Duarte

“…DIN concentrations were between 8 and 140 times higher, and DIP concentrations were between 1 and 75 times higher than those in previous studies, highlighting the need for a comprehensive monitoring program. Pb and Hg Enrichment Factors (EF) and Sediment Quality Guideline-Quotient (SQG-Q) indicated the presence of anthropogenic contamination with high potential for specific adverse biological effects. …”
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VELEBIT I ZAŠTITA PRIRODE by ZORAN ŠIKIĆ, DENIS GURLICA, TOMISLAV ŠARIĆ

“…Da li je i na koji način zaštita prirode doprinos opstanku i održivom razvoju velebitske regije i posebno lokalne zajednice tog područja još uvijek je aktualno pitanje te također, je li na ovome prostoru moguće povezati opće i globalne izazove današnjice s onim lokalnim. …”
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Unravelling the multi-scale structure of vertebrate scavenger communities: The role of beta-diversity in livestock carcass consumption by María Eugenia Cabrera-García, Patricia Mateo-Tomás, José Hernán Sarasola, Juan I. Zanón Martínez, Beatriz Martínez-Miranzo, Pedro P. Olea

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The ASK-16 motorized glider: an airborne eddy covariance platform to measure turbulence, energy, and matter fluxes by I. Wiekenkamp, A. K. Lehmann, A. Bütow, J. Hartmann, S. Metzger, S. Metzger, T. Ruhtz, C. Wille, M. Zöllner, T. Sachs, T. Sachs

“…The glider is equipped with an 858 AJ Rosemount five-hole probe, a Picarro G2311-f gas analyzer, a Novatel FlexPak G2-V2 GNSS–INS system, Vaisala temperature and humidity sensors (HMT311), and an OMEGA CHAL-003 thermocouple temperature sensor. …”
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Study on the status of liver function abnormalities and its related factors in patients with severe mental disorders in Shanghai community by ZHANG Yixuan, CHEN Chunmei, ZHU Youwei, ZHU Yi, HE Siyuan, LIU Yanli, WANG Na, CAI Jun, XIE Bin, ZHANG Weibo

“…Univariate analysis showed that the rate of liver function abnormalities was higher in males than that in females (χ2=45.026, P<0.001), higher in suburbs than that in urban areas (χ2=25.317, P<0.001), higher in those with higher BMI than in those with lower BMI (χ2=63.748, P<0.001), higher in those with elevated blood pressure (BP) than in those without elevated BP (χ2=24.774, P<0.001), higher in those with elevated blood glucose than in those without elevated blood glucose (χ2=43.345, P<0.001), higher in those with abnormal triglyceride (TG) than in those with normal TG (χ2=15.551, P<0.001), and higher in those with abnormal total cholesterol (TC) than in those with normal TC (χ2=10.962, P=0.001). …”
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Evidence construction of Silibinin capsules against alcoholic liver disease based on a meta-analysis and systematic review by Yan Wang, Yan Wang, Wenmin Yang, Wenmin Yang, Yuan Yang, Yuan Yang, Xingning Liu, Xingning Liu, Lanfen Peng, Lanfen Peng, Qi Huang, Qi Huang, Qi Huang, Kongli Fan, Kongli Fan, Rui Hu, Rui Hu, Jinyu Yi, Jinyu Yi, Xin Zhong, Xin Zhong, Jing Li, Jialing Sun, Xiaozhou Zhou, Xiaozhou Zhou

“…Primary outcomes included liver function indicators such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), total bilirubin (TBIL), lipid indicators including triglycerides (TG) and total cholesterol (TC), coagulation indicators including prothrombin time (PT), liver fibrosis indicator (PC-III), and Effective Rate. …”
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Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

“…Most patients developed hypothyroidism. Two-third of patients showed FT4 values below the lower limit at 1 week. …”
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On Minimum-Latency Broadcast in Multichannel Duty-Cycled Wireless Sensor Networks by Xianlong Jiao, Weidong Xiao, Bin Ge, Yuli Chen

“…We propose a new concept of active interference graph (AIG). Based on AIG, we present one novel approximation broadcast algorithm called NAB to solve the MLBCD problem. …”
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tRNA Modification and Genetic Code Variations in Animal Mitochondria by Kimitsuna Watanabe, Shin-ichi Yokobori

“…They are UGA (termination codon in the universal genetic code changes to Trp codon in all animal mitochondria), AUA (Ile to Met in most metazoan mitochondria), AAA (Lys to Asn in echinoderm and some platyhelminth mitochondria), AGA/AGG (Arg to Ser in most invertebrate, Arg to Gly in tunicate, and Arg to termination in vertebrate mitochondria), and UAA (termination to Tyr in a planaria and a nematode mitochondria, but conclusive evidence is lacking in this case). …”
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Determination of Mycotoxin Contamination Levels in Rice and Dietary Exposure Assessment by Jose Troestch, Stephany Reyes, Aracelly Vega

“…For the method used, the detection limits were lower than 0.25 μg/Kg for aflatoxins (AFB1, AFB2, AFG1, AFG2) and ochratoxin A and 9.35 μg/Kg for zearalenone; the limits of quantification were between 0.25 and 18.75 μg/Kg, respectively. …”
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Articular Cartilage Gene Expression after Coxofemoral Joint Luxation in the Dog by Korakot Nganvongpanit, Waranee Pradit, Siriwadee Chomdej

“…Ten mRNA, including nonapoptotic genes (AGG, COL2A1, MMP-3, HAS-1, HAS-2, and TIMP-1) and apoptotic genes (BAX, BCL-2, CAS-3, and CAS-9), were studied for their expression using real-time PCR. …”
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