CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics by Young-Kyu Park, Tae-Wook Kang, Su-Jin Baek, Kwon-Il Kim, Seon-Young Kim, Doheon Lee, Yong Sung Kim

“…With this tool, researchers can classify their candidate genes from cancer genome studies into either previously reported or novel categories of cancer genes and gain insight into underlying carcinogenic mechanisms through a pathway analysis. We show the usefulness of CaGe by assessing its performance in annotating somatic mutations from a published small cell lung cancer study.…”
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Establishment of an Experimental Procedure for Preparing Trial Serum Samples for the Specific Serodiagnosis of Toxocara canis for External Quality Assessment Schemes by Quang Huy Vu, Diep Tuan Tran, Phu Manh Sieu Tran, Van Chuong Le, Thi Diem Phuc Huynh, Quang Sang Bui

“…Among eleven samples positive by ELISA, ten of them were confirmed via Western blotting by positive reaction with 5 specific Toxocara canis bands. …”
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Liver diseases: epidemiology, causes, trends and predictions by Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao

“…However, there is no cure for many kinds of liver diseases, partly due to a lack of thorough understanding of the development of these liver diseases. …”
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GP73-mediated secretion of PKM2 and GP73 promotes angiogenesis and M2-like macrophage polarization in hepatocellular carcinoma by Shujie Wang, Tongjia Zhang, Yue Zhou, Zitao Jiao, Kejia Lu, Xinyi Liu, Wei Jiang, Zhe Yang, Hui Li, Xiaowei Zhang

“…Abstract Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Abnormally high expression of Golgi protein 73 (GP73) and pyruvate kinase M2 (PKM2) is intimately associated with HCC progression. …”
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Flexible, tough and high-performing ionogels for supercapacitor application by Paulina Pietrzyk-Thel, Amrita Jain, Kamil Bochenek, Monika Michalska, Michał Basista, Tamas Szabo, Peter B. Nagy, Anna Wolska, Marcin Klepka

“…The supercapacitor cell fabricated using the optimized ionogel film showed a capacitance of 39.9 F/g with an energy and power densities of 5.5 W⋅h/kg and 0.3 kW/kg, respectively confirming the suitability of ionogels for supercapacitor application.…”
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Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors by Song Li, Yunheng Liu, Xiaokang Zhang, Yurong Liu, Longqing Si, Shaojing Jiang, Aoya Wang, Xukai Che, Jing Chen, Jinghui Hu

“…After endocytosis, D/I@HST NPs generate ROS under 808-nm laser irradiation, breaking the ROS-responsive crosslinking agent and increasing drug release and utilization. Tf also carries Fe3+, which is reduced to Fe2+ by iron reductase in the acidic tumor microenvironment (TME). …”
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Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice by Chi Lieu Kim Nguyen, Yumeno Kuba, Hoai Thu Le, Hossam Hassan Shawki, Natsuki Mikami, Madoka Aoki, Nanako Yasuhara, Hayate Suzuki, Saori Mizuno-Iijima, Shinya Ayabe, Yuki Osawa, Tomoyuki Fujiyama, Tra Thi Huong Dinh, Miyuki Ishida, Yoko Daitoku, Yoko Tanimoto, Kazuya Murata, Woojin Kang, Masatsugu Ema, Yuji Hirao, Atsuo Ogura, Satoru Takahashi, Fumihiro Sugiyama, Seiya Mizuno

“…Our study reveals that the exocyst complex, a heterotetrameric protein complex important for tethering in vesicular transport, is important for proper intra-oocyte trafficking of c-KIT and GDF9 in mice. We found that depletion of oocyte-specific EXOC1, a component of the exocyst complex, impaired oocyte re-awakening and cyst breakdown, and inhibited granulosa cell proliferation during follicle growth. …”
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Development of interaction management tools in B2B markets by M. V. Orlova, V. V. Orlov

Subjects: “…account-based engagement (abe)…”
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Optimization of meropenem continuous infusion based on Monte Carlo simulation integrating with degradation study. by Nguyen Tran Nam Tien, Vu Ngan Binh, Pham Thi Thanh Ha, Dang Thi Ngoc Lan, Yong-Soon Cho, Nguyen Phuoc Long, Jae-Gook Shin, Nguyen Hoang Anh, Truong Anh Quan, Do Ngoc Tuan, Nguyen Khac Tiep, Pham The Thach, Nguyen Hoang Anh, Vu Dinh Hoa

“…PLoS ONE…”
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Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study by Shiming He, Shiming He, Shiming He, Chao Wang, Chao Wang, Chao Wang, Xin Huang, Xin Huang, Xin Huang, Guoan Jian, Guoan Jian, Guoan Jian, Zihao Lu, Zihao Lu, Zihao Lu, Kun Jiang, Kun Jiang, Kun Jiang, Guobo Xie, Guotai Sheng, Yang Zou

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Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

“…Additionally, the articles should report objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS) or time to progression (TTP); the treatment effect of these endpoints, OR or HR, should be based on central and local assessments.Results Of 76 included trials involving 45 688 patients, 17 (22%) trials reported their endpoints with statistically inconsistent inferences (p value lower/higher than the probability of type I error) between central and local assessments; among them, 9 (53%) trials had statistically significant inference based on central assessment. …”
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Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS by Zi-yue Dong, Ming-jie He, Yong-kai Yu, Fang Wang, Peng-yuan Zhao, De-long Ran, De-shuang Fu, Qing He, Run-ping Yang, Jiang-an Zhang

“…The study aims to delineate the genetic and molecular mechanisms of vitiligo pathogenesis using an integrative multiomics strategy. We focus on exploring the regulatory influence of the JAK/STAT pathway on Cathepsin S, a potential therapeutic target in vitiligo. …”
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Distributions, Sources, and Backward Trajectories of Atmospheric Polycyclic Aromatic Hydrocarbons at Lake Small Baiyangdian, Northern China by Ning Qin, Xiang-Zhen Kong, Ying Zhu, Wei He, Qi-Shuang He, Bin Yang, Hui-Ling Ou-Yang, Wen-Xiu Liu, Qing-Mei Wang, Fu-Liu Xu

“…Gas phase, particulate phase and dust fall concentrations of polycyclic aromatic hydrocarbons (PAHs) were measured using a gas chromatograph-mass spectrometer (GC-MS). …”
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Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury by Wen-zhao Liu, Zhan-jun Ma, Ji-he Kang, Ai-xin Lin, Zhao-heng Wang, Hai-wei Chen, Xu-dong Guo, Xue-gang He, Xue-wen Kang

“…We found that GSP regulated microglial polarisation and inhibited apoptosis in PC12 cells induced by M1-BV2 cells through the Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa B (NF-κB) and phosphatidylinositol 3-kinase/serine threonine kinase (PI3K/AKT) signaling pathways. …”
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NUCB2/Nesfatin-1 Regulation of Chronic Visceral Hyperalgesia by Qiaoyan Gu, Yuan Lei, Jianming Wu, Ting He, Juanjuan Li, Shanshan Song

“…Objective. We previously described that different concentration Nucleobindin-2 (NUCB2)/Nesfatin-1 gradients differently regulated visceral hypersensitivity in irritable bowel syndrome. …”
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ANALYSIS SCHEME FOR MULTI-FAULTS VIBRATION OF GEARBOX BASED ON DISCRETE RANDOM SEPARATION by HE DongTai, GUO Yu, WU Xing, LIU ZhiQi, ZHAO Lei

“…Test results show that this method can be used to extract the gear and bearing fault features effectively.…”
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The Antifibrosis Effects of Peroxisome Proliferator-Activated Receptor δ on Rat Corneal Wound Healing after Excimer Laser Keratectomy by Yun Gu, Xuan Li, Tiangeng He, Zhixin Jiang, Peng Hao, Xin Tang

“…A myofibroblast marker (α-smooth muscle actin) and ECM production (fibronectin, collagen type III and collagen type I) were examined by immunohistochemistry and RT-PCR. …”
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Method of multilayer object sectioning based on a light scattering model by S.D. Bazhitov, A.V. Larichev, A.V. Razgulin, T.E. Romanenko

“…We propose a method of "Boundary separation" of sectioning, which combines the use of a physical blur model with modern methods of blur estimating and edge detection. …”
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Tactical intent-driven autonomous air combat behavior generation method by Xingyu Wang, Zhen Yang, Shiyuan Chai, Jichuan Huang, Yupeng He, Deyun Zhou

“…The superior performance and stability of the proposed algorithm compared to other algorithms are captured by our empirical results. …”
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Robust feature selection method via joint low-rank reconstruction and projection reconstruction by Shuangyan YI, Yongsheng LIANG, Jingjing LU, Wei LIU, Tao HU, Zhenyu HE

“…Aiming at the problem that current feature selection methods were still affected by noise and cannot effectively unify clustering and reconstruction effects, a robust feature selection method was proposed.A robust reconstruction error term was built by making the difference between low-rank reconstruction and projection reconstruction.After that, the features for clustering were selected from the reconstructed data instead of the original data.The learning of clean data and feature selection technique are allowed for joint learning and promote each other, thereby improving the robustness of the method on noisy data, and effectively unifying reconstruction and clustering.Compared with several kinds of graph embedding feature selection and reconstruction feature selection methods on five datasets, the experimental results showed that, except for the LUNG noise dataset, the proposed method outperforms the comparative feature selection method under both evaluation indicators (ACC and NMI).…”
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