Showing 5,461 - 5,480 results of 30,022 for search 'THE~', query time: 1.21s Refine Results
  1. 5461

    Liver diseases: epidemiology, causes, trends and predictions by Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao

    Published 2025-02-01
    “…However, there is no cure for many kinds of liver diseases, partly due to a lack of thorough understanding of the development of these liver diseases. …”
    Get full text
    Article
  2. 5462

    GP73-mediated secretion of PKM2 and GP73 promotes angiogenesis and M2-like macrophage polarization in hepatocellular carcinoma by Shujie Wang, Tongjia Zhang, Yue Zhou, Zitao Jiao, Kejia Lu, Xinyi Liu, Wei Jiang, Zhe Yang, Hui Li, Xiaowei Zhang

    Published 2025-02-01
    “…Abstract Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Abnormally high expression of Golgi protein 73 (GP73) and pyruvate kinase M2 (PKM2) is intimately associated with HCC progression. …”
    Get full text
    Article
  3. 5463

    Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors by Song Li, Yunheng Liu, Xiaokang Zhang, Yurong Liu, Longqing Si, Shaojing Jiang, Aoya Wang, Xukai Che, Jing Chen, Jinghui Hu

    Published 2025-01-01
    “…After endocytosis, D/I@HST NPs generate ROS under 808-nm laser irradiation, breaking the ROS-responsive crosslinking agent and increasing drug release and utilization. Tf also carries Fe3+, which is reduced to Fe2+ by iron reductase in the acidic tumor microenvironment (TME). …”
    Get full text
    Article
  4. 5464

    THE NEW WORLD INFORMATION AND COMMUNICATION ORDER DEBATE AND THE DEVELOPMENT OF INFORMATION AND COMMUNICATION TECHNOLOGY IN NIGERIA by BECKY ADE ALIEGBA

    Published 2023-09-01
    “…The study was underpinned on the National System of Innovation (NSI) and the News Framing theory, and adopted the mixed research method using historical and content analysis. It also relied on secondary sources of data. …”
    Get full text
    Article
  5. 5465

    EVALUATION OF TIMELY PASSING PROGRAM DEPARTMENT OF INDONESIAN LANGUAGE EDUCATION UNIVERSITAS INDRAPRASTA PGRI by Ade Siti Haryanti

    Published 2021-12-01
    Subjects: “…evaluation, graduated on-time, countenance stake…”
    Get full text
    Article
  6. 5466
  7. 5467

    Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

    Published 2018-09-01
    “…Additionally, the articles should report objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS) or time to progression (TTP); the treatment effect of these endpoints, OR or HR, should be based on central and local assessments.Results Of 76 included trials involving 45 688 patients, 17 (22%) trials reported their endpoints with statistically inconsistent inferences (p value lower/higher than the probability of type I error) between central and local assessments; among them, 9 (53%) trials had statistically significant inference based on central assessment. …”
    Get full text
    Article
  8. 5468

    Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS by Zi-yue Dong, Ming-jie He, Yong-kai Yu, Fang Wang, Peng-yuan Zhao, De-long Ran, De-shuang Fu, Qing He, Run-ping Yang, Jiang-an Zhang

    Published 2025-01-01
    “…The study aims to delineate the genetic and molecular mechanisms of vitiligo pathogenesis using an integrative multiomics strategy. We focus on exploring the regulatory influence of the JAK/STAT pathway on Cathepsin S, a potential therapeutic target in vitiligo. …”
    Get full text
    Article
  9. 5469

    Distributions, Sources, and Backward Trajectories of Atmospheric Polycyclic Aromatic Hydrocarbons at Lake Small Baiyangdian, Northern China by Ning Qin, Xiang-Zhen Kong, Ying Zhu, Wei He, Qi-Shuang He, Bin Yang, Hui-Ling Ou-Yang, Wen-Xiu Liu, Qing-Mei Wang, Fu-Liu Xu

    Published 2012-01-01
    “…Gas phase, particulate phase and dust fall concentrations of polycyclic aromatic hydrocarbons (PAHs) were measured using a gas chromatograph-mass spectrometer (GC-MS). …”
    Get full text
    Article
  10. 5470

    Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury by Wen-zhao Liu, Zhan-jun Ma, Ji-he Kang, Ai-xin Lin, Zhao-heng Wang, Hai-wei Chen, Xu-dong Guo, Xue-gang He, Xue-wen Kang

    Published 2022-01-01
    “…We found that GSP regulated microglial polarisation and inhibited apoptosis in PC12 cells induced by M1-BV2 cells through the Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa B (NF-κB) and phosphatidylinositol 3-kinase/serine threonine kinase (PI3K/AKT) signaling pathways. …”
    Get full text
    Article
  11. 5471
  12. 5472
  13. 5473
  14. 5474
  15. 5475
  16. 5476
  17. 5477
  18. 5478
  19. 5479
  20. 5480