Adult hypophosphatasia presenting with recurrent acute joint pain by Hayao Yoshida, Takaaki Murakami, Atsubumi Ogawa, Takashi Sunouchi, Naoko Hidaka, Nobuaki Ito, Hiromi Murakami, Hidenori Kawasaki, Tomoyuki Akiyama, Katsumi Nakajima, Daisuke Yabe, Taizo Yamamoto

“…While the patient had no history of premature loss of primary teeth, fragility fractures, muscle weakness or abnormalities in growth, genetic testing revealed a likely pathogenic and a pathogenic heterozygous variant in the ALPL gene, i.e., c.979T>C (p.Phe327Leu) and c.1559del (p.Leu520Argfs), confirming HPP. …”
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The crisis of the concept of society: historiosophical and sociological search by Irena Eglė Laumenskaitė

“…The historical investigation of society could gain by addressing the main problems of contemporary theoretical research in sociology. One of them is the problem of the agent of social reality, without reducing it to social structures or to social individuals as a set of social roles, which are imputed on him/her by society. …”
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Factores asociados a la procrastinación académica en estudiantes de Estomatología de siete universidades cubanas by Ibraín Enrique Corrales-Reyes, Mónica García-Raga, José Daniel Villegas-Maestre, Leonardo Valdés-Gamboa, Adrián Alejandro Vitón-Castillo, Diana Tusell-Hormigó, Christian R. Mejia

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Amyand’s Hernia: Rare Presentation of a Common Ailment by Sanjeev Singhal, Anu Singhal, Sanjay Singh Negi, Rahul Tugnait, Pankaj Kumar Arora, Bishwanath Tiwari, Pawan Malik, Lav Gupta, Amit Bimal, Abhishek Gupta, Rahul Gupta, Pushkar Chouhan, ChandraKant Singh

“…She was initially managed conservatively and subsequently underwent exploratory laparatomy. …”
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Inhibition of the Ubiquitin-Activating Enzyme UBA1 Suppresses Diet-Induced Atherosclerosis in Apolipoprotein E-Knockout Mice by Jiawei Liao, Xiaolei Yang, Qiuyue Lin, Shuang Liu, Yunpeng Xie, Yunlong Xia, Hui-Hua Li

“…Ubiquitin-like modifier activating enzyme 1 (UBA1) is the first and major E1 activating enzyme in ubiquitin activation, the initial step of the ubiquitin-proteasome system. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

Subjects: “…Thrombotic thrombocytopenic purpura (TTP)…”
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Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides by Lucia Vrablova, Tomas Gonec, Tereza Kauerova, Michal Oravec, Izabela Jendrzejewska, Peter Kollar, Alois Cizek, Josef Jampilek

“…Cytotoxicity on human cells was also tested. Key results: Three compounds showed activity comparable to clinically used drugs. …”
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy by M. Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang, Zhen Wang, Joydeep Mitra, Nha Nguyen, Tina Gao, Mark Khusidman, Sanish Sathyan, Gil Atzmon, Sofiya Milman, Jan Vijg, Nir Barzilai, Zhengdong D. Zhang

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Prolonged Survival following Repetitive Stereotactic Radiosurgery in a Patient with Intracranial Metastatic Renal Cell Carcinoma by Ethan A. Ferrel, Andrew T. Roehrig, Wayne T. Lamoreaux, Alexander R. Mackay, Robert K. Fairbanks, Jason A. Call, Jonathan D. Carlson, Benjamin C. Ling, John J. Demakas, Barton S. Cooke, Aaron Wagner, Christopher M. Lee

“…The patient’s first GKRS treatment targeted four lesions with 22 Gy at the 50% isodose line. She underwent a total of seven GKRS treatments over the next 60 months for recurrent metastases to the brain. 72 months and 12 months have now passed since her brain metastases were first discovered and since her last GKRS treatment, respectively, and this woman is alive with considerable quality of life and no evidence of metastatic reoccurrence. …”
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Novel application of an imageless robotic system in simultaneous unicompartmental knee arthroplasty and anterior cruciate ligament reconstruction by Joshua Yeuk Shun Tran, Rex Wang-Fung Mak, Kevin Ki-Wai Ho, Jonathan Patrick Ng, Cham Kit Wong, Gloria Yan-Ting Lam, Tsz Lung Choi, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

“…This technical note explores the novel use of an imageless robotic surgical system for simultaneous unicompartmental knee arthroplasty (UKA) and anterior cruciate ligament reconstruction (ACLR). …”
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Transcatheter edge‐to‐edge tricuspid repair for recurrence of valvular regurgitation after left ventricular assist device and tricuspid ring implantation by Martin Andreas, Marco Russo, Paul Werner, Matthias Schneider, Franziska Wittmann, Sabine Scherzer, Julia Mascherbauer, Alfred Kocher, Guenther Laufer, Dominik Wiedemann, Daniel Zimpfer

“…Tricuspid regurgitation was reduced by 50% (postoperative EROA 0.7 cm2). She remained stable under continuous inotropic support with no other episodes of right ventricular decompensation and was successfully transplanted 30 days after the clipping procedure. …”
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Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy by Masanori Murakami, Noriko Matsushita, Rie Arai, Naohiro Takahashi, Ryuki Kawamura, Sayaka Suzuki, Sachio Takekawa, Fumiko Iwashima, Takashi Shibui, Akihiro Hata, Yoshihiro Ogawa, Toshiyuki Horiuchi

“…After admission, she went into a delirious state and suffered from takotsubo cardiomyopathy due to adrenal insufficiency. …”
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Validez y confiabilidad de una escala de procrastinación académica en estudiantes cubanos de Estomatología by Ibraín Enrique Corrales-Reyes, José Daniel Villegas-Maestre, Adrián Alejandro Vitón-Castillo, Diana Tusell-Hormigó, Oscar Javier Mamani-Benito, Renzo Felipe Carranza-Esteban

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Socio-economic assessment of dog population management systems: a scoping review by Rabina Ghimire, Parimala Mohanty, Elly Hiby, Andrew Larkins, Andrew Larkins, Salome Dürr, Sonja Hartnack

“…The studies revealed diverse approaches to DPM, sterilization being the most frequently used service, often combined with vaccination and community awareness. …”
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Perioperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement: an observational study by Gehad Awad, Fetoh Alaaeldin Fetoh, Noureldin Noaman Gwely, Usama Hamza, Sameh Amer, Yomna Mohammed Yehya, Amr Abdellateef

“…The intraoperative assessment by TEE showed a well-suited, well-functioning prosthetic valve, and no paravalvular leak in the two groups. …”
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E3泛素-蛋白连接酶Parkin介导线粒体自噬参与荷瘤小鼠心肌损伤 by 邓世杰, 李兴会, 蔡卫斌

“…目的观察荷瘤状态下小鼠心肌损伤情况，探讨<italic>park2</italic>基因编码的E3泛素-蛋白连接酶Parkin介导线粒体自噬在荷瘤小鼠心肌损伤中的作用及机制。方法通过PCR和蛋白质免疫印迹筛选和鉴定<italic>park2</italic>^-/-小鼠；通过皮下移植瘤技术构建荷瘤动物模型，采用小动物心脏超声分析小鼠心脏结构与功能，观察心室内径、心室容积、射血分数、缩短分数以及心室壁厚度的变化；采用病理学方法分析小鼠心脏的形态学特征；使用Fluo-3、Rhod-2、DHE-ROS及JC-1探针进行线粒体损伤指标检测；通过qPCR技术分析线粒体生成相关因子tfam，nrf1，线粒体融合相关因子opa1，mfn2，线粒体分裂相关因子fis1，线粒体自噬相关因子park2表达改变；通过Western Blot技术检测关键蛋白LC3 Ⅱ、LC3 Ⅰ、Parkin表达水平。…”
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Three novel umami peptides derived from the alcohol extract of the Pacific oyster (Crassostrea gigas): Identification, characterizations and interactions with T1R1/T1R3 taste receptors by Baifeng Fu, Di Wu, Shuzhen Cheng, Xianbing Xu, Ling Zhang, Lishu Wang, Hesham R. El-Seedi, Hanxiong Liu, Ming Du

“…Oyster (Crassostrea gigas), the main ingredient of oyster sauce, has a strong umami taste. In this study, three potential umami peptides, FLNQDEEAR (FR-9), FNKEE (FE-5), and EEFLK (EK-5), were identified and screened from the alcoholic extracts of the oyster using nano-HPLC-MS/MS analysis, iUmami-Scoring Card Method (iUmami-SCM) database and molecular docking (MD). …”
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Outcome of Pleural Empyema Treated With Video-Assisted Thoracoscopic Surgery in Patients With Severe Co-Morbidities: An Observational Study by Vu HA, Nguyen NV, Le TD, Nguyen ST, Viet Le A, The Vu A, Van Nguyen B, Van Nguyen B, Thanh Quan N, An NV, Duc Nghiem T

“…Hai Anh Vu,1 Nam Van Nguyen,1 Tuan Dinh Le,2 Son Tien Nguyen,2 Anh Viet Le,1 Anh The Vu,3 Ba Van Nguyen,4 Binh Van Nguyen,5 Nam Thanh Quan,6 Nguyen Van An,7 Thuan Duc Nghiem6 1Department of Thoracic Surgery, Military Hospital 103, Vietnam Medical Military University, Hanoi, 10000, Vietnam; 2Department of Rheumatology and Endocrinology, Military Hospital 103, Vietnam Medical Military University, Hanoi, 10000, Vietnam; 3Department of Anesthesia and Pain Medicine, Military Hospital 103, Vietnam Medical Military University, Hanoi, 10000, Vietnam; 4Department of Oncology, Military Hospital 103, Vietnam Medical Military University, Hanoi, 1000, Vietnam; 5AIDS Healthcare Foundation, Hanoi, 10000, Vietnam; 6Department of Otolaryngology, Military Hospital 103, Vietnam Medical Military University, Hanoi, 10000, Vietnam; 7Department of Microbiology Department, Military Hospital 103, Vietnam Medical Military University, Hanoi, 10000, VietnamCorrespondence: Thuan Duc Nghiem, Department of Otolaryngology, Military Hospital 103, Vietnam Medical Military University, 160 Phung Hung Street, Phuc La Ward, ha Dong District, Hanoi, 100000, Vietnam, Email nghiemducthuan@vmmu.edu.vnBackground: Empyema patients with poor physical condition and severe comorbidities face a significant challenge, with difficulties in choosing appropriate treatment methods, limited treatment outcomes, and a high rate of complications and mortality.Objective: To comment on the indications and to evaluate the treatment outcomes of pleural empyema in patients with poor physical condition and severe comorbidities by thoracoscopic surgery.Methods: An observational study on 12 patients treated at the Department of Thoracic Surgery – Military Hospital 103, from January 2017 to December 2022.Results: The mean of age was 63.4 ± 12.4 years old, with a male/female ratio of 5/1. …”
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The influence of different radiopacifying agents on hermetical sealing ability of calcium silicate and calcium aluminate dental cements by Ćetković Dejan, Zhiyu Cai, Vuković Nemanja, Vuković Zorica, Lei Huaxiang, Biočanin Vladimir, Huang Xiaojing, Jokanović Vukoman, Antonijević Đorđe, Dožić Aleksandra

“…There was no difference in total SFE among tested cements (p<0.05), while CaSi+BaSO4, CaAl + SrCO3 and CaAl + SrF2 experienced superior wetting than other cements (p<0.05). …”
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