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85501
3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3
Published 2025-01-01“…Notably, IGF2BP1 was found to inhibit the recruitment of the BTG2/CCR4-NOT complex by competitively binding to PABPC1, thereby preventing the deadenylation of NLRP3 mRNA and maintaining its expression. …”
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85502
Effect of cooperative learning strategy on students’ acquisition and practice of scientific skills in Biology
Published 2017-03-01“…Therefore, cooperative learning has been proposed by many educators to be implemented in classrooms to produce lifelong learners and critical thinkers (Lunenburg, 2011). …”
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85503
Case report: a rare case of diffusely metastatic BRAF V600E-mutated colorectal cancer with concomitant infiltration of the skin and parotid gland
Published 2025-01-01“…The patient’s rapid disease progression did not allow for any therapeutic interventions. This is only the second report of concomitant metastatic infiltration of the skin and parotid gland by CRC, and the first with a documented molecular background of BRAF V600E mutation. …”
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85504
Chinese Scholars on the Progress and Outcomes of the Military Reforms in Russia (from the 1990s till Present)
Published 2021-10-01“…The general failure of military reforms is attributed to the economic challenges, the lack of political will, and the absence of an adequate theoretical and methodological basis for such transformations. …”
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85505
Is Freezing of Gait in Parkinson's Disease a Result of Multiple Gait Impairments? Implications for Treatment
Published 2012-01-01“…We suggest that these seemingly independent gait features may have mutual interactions which, during certain circumstances, jointly drive the predisposed locomotion system into a FOG episode. This new theoretical framework is illustrated by the evaluation of the potential relationships between the so-called “sequence effect”, that is, impairments in step scaling, and gait asymmetry just prior to FOG. …”
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85506
CONSTRAINTS OF PROJECT MANAGEMENT IN THE NIGERIAN CONSTRUCTION INDUSTRY
Published 2024-03-01“…The recommendations, therefore, emphasized training programs, standard regulation protocol, and effective government policy to ensure effective project delivery in the Nigerian construction industry. …”
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85507
Mathematical Modeling of Wax Deposition in Field-Scale Crude Oil Pipeline Systems
Published 2022-01-01“…The findings of this study will help in making informed decisions on the planning of pigging operations, thermal insulation, and other remediation techniques to be applied in controlling wax deposition in field-scale crude oil pipeline systems.…”
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85508
QAR (QUESTION ANSWER RELATIONSHIP) AS AN ALTERNATIVE STRATEGY TO TEACH READING
Published 2017-01-01“…However, if the students have difficulties dealing with these reading comprehension questions, a teacher must be able to help them by introducing reading strategies to overcome the problems. …”
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85509
PERFORMANCE REQUIRED FOR COMMON-USE COMPONENTS OF COMPUTER NETWORKS
Published 2024-09-01“…For such an adjustment, two algorithms are proposed. One of them solves the problem by reducing it to that of backpack. …”
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85510
Do Upper and Lower Camptocormias Affect Gait and Postural Control in Patients with Parkinson’s Disease? An Observational Cross-Sectional Study
Published 2019-01-01“…Two types of CC affect patients with PD, but no studies investigated their relative contribution in worsening gait and postural control. Therefore, we investigated spatiotemporal gait parameters, gait variability, and asymmetry and postural control in PD patients (Hoehn & Yahr ≤4) with upper CC and lower CC and patients without CC. …”
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85511
Treatment of neuro-invasive listeriosis: an overview
Published 2018-12-01“…In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. First-line recommended therapy is a combination of amoxicillin and gentamicin intravenously. …”
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85512
CALCULATION OF CORRECTION FACTORS FOR EPITHERMAL NEUTRON SELF-SHIELDING IN Au-197
Published 2018-08-01“…In this research, the characteristics of neutron irradiation facility at the thermal column of the Dalat Nuclear Research Reactor were used as the input parameters for the neutron source definition. …”
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85513
Study on the Migration Law of Overlying Strata on the Working Surface of Large Mining Height in Y.C.W Coal Mine
Published 2022-01-01“…The theoretical calculation results show that there are “one main two sub” key strata in the overlying strata of 130204 working face, which play an important role in controlling rock movement. …”
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85514
Economic Approach to Valuing Information with Applications to Climate Information
Published 2009-06-01“…Specifically, it discusses a way to evaluate the information in Florida climate forecasts in order to improve agriculture decisions and thereby produce more reliable economic outcomes. Includes references. …”
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85515
Productivity and ecological functions of naturally regrown pine forests of the Ukrainian Polissia
Published 2024-10-01“…Thus, 1 hectare of the forest already at the age of 10 years can accumulate up to 30 tons of carbon only in the above-ground part, which is a significant contribution to the overall balance of the implementation of the ecosystem function of forests, therefore they require protection and proper forest management.…”
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85516
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19
Published 2021-01-01“…Here, we discuss the mechanistic basis for the use of HCQ against SARS-CoV-2 in a prophylactic setting and in a therapeutic setting, at different stages of the disease. …”
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85517
Local media reporting and influence on political communication in the North of Kosovo and Metohija
Published 2024-01-01“…The influence of the media on the formation of public opinion is undeniable, regardless of which sphere of social and public importance is in focus. The political theory sees public opinion as a phenomenon of political practice essential for political activities, which was emphasized by some of our theoreticians (e.g. …”
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85518
Thirty Years Later: Evolution of Treatment for Acute Left Main Coronary Artery Occlusion
Published 2016-01-01“…These patients exemplify the progress in therapeutic cardiology over the last 30 years.…”
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85519
High‐Throughput Single‐Nucleus RNA Profiling of Minimal Puncture FFPE Samples Reveals Spatiotemporal Heterogeneity of Cancer
Published 2025-01-01“…Utilizing 7 puncture FFPE samples of liver metastases from 3 colorectal cancer patients pre‐ and post‐immunotherapy, the cellular developmental trajectories are reconstructed and revealed dynamic spatiotemporal heterogeneity during treatment, including insights into pseudoprogression of immunotherapy. Therefore, the optimized snRandom‐seq offers a solution for high‐throughput single‐cell RNA and non‐coding RNA analysis in minimal puncture FFPE sample.…”
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85520
In Vivo Evaluation of the Ameliorating Effects of Small-Volume Resuscitation with Four Different Fluids on Endotoxemia-Induced Kidney Injury
Published 2015-01-01“…Fluid resuscitation is the main therapy. However, heart failure is usually lethal for those patients receiving large volumes of fluids. …”
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