The Effect of Statins and Other Cardiovascular Medication on Ischemia-Reperfusion Damage in a Human DIEP Flap Model: Theoretical and Epidemiological Considerations by M. G. W. van den Heuvel, A. Bast, A. W. Ambergen, R. R. W. J. van der Hulst

“…Chronic use of statins or other cardiovascular medication didnot decrease the occurrence of I/R related complications after DIEP surgery. Therefore, research should be aimed at evaluating short-term pre-treatment with statins.…”
Get full text

HAPLOIDENTICAL TRANSPLANT WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE FOR ACUTE MYELOID LEUKAEMIA AND MYELODYSPLASTIC SYNDROMES PATIENTS: THE ROLE OF PREVIOUS LINES OF THERAPY. by Daniele Avenoso, Fabio Serpenti, Liron Barnea Slonim, Styliani Bouziana, Francesco Dazzi, Guy Hannah, Michelle Kenyon, Varun Mehra, Austin Kulasekararaj, Pramila Krishnamurthy, Mili Naresh Shah, Sharon Lionel, Antonio Pagliuca, Victoria Potter

“…The median OS in patients with >2 previous lines of therapy and ≤2 lines of therapy was 16 and 49 months, respectively. …”
Get full text

Delivery Parameter Variations and Early Clinical Outcomes of Volumetric Modulated Arc Therapy for 31 Prostate Cancer Patients: An Intercomparison of Three Treatment Planning Systems by Shinichi Tsutsumi, Masako N. Hosono, Daisaku Tatsumi, Yoshitaka Miki, Yutaka Masuoka, Ryo Ogino, Kentaro Ishii, Yasuhiko Shimatani, Yukio Miki

“…We created volumetric modulated arc therapy (VMAT) plans for 31 prostate cancer patients using one of three treatment planning systems (TPSs)—ERGO++, Monaco, or Pinnacle—and then treated those patients. …”
Get full text

Coupled Coincidence Point and Coupled Fixed Point Theorems via Generalized Meir-Keeler Type Contractions by Hassen Aydi, Erdal Karapınar, İnci M. Erhan

Get full text

A theory of nonlinear wave loading on offshore structures by Lokenath Debnath, Matiur Rahman

“…A theoretical study is made of the nonlinear wave loading on offshore structures using the diffraction theory of hydrodynamics. …”
Get full text

Charge heterogeneity of therapeutic monoclonal antibodies by different cIEF systems: views on the current situation by Alessandro Ascione, Marcello Belfiore, Jaana Vesterinen, Mihaela Buda, Wolf Holtkamp, Francesca Luciani

“…Therapeutic mAbs show a specific “charge fingerprint” that may affect safety and efficacy, and, as such, it is often identified as a critical quality attribute (CQA). …”
Get full text

Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study by Heng‐Chung Kung, Jun Yu

Subjects: “…neoadjuvant therapy…”
Get full text

Anaerobic external combustion thermal engines by V. I. Karagusov

Subjects: Get full text

Switch to Aflibercept in Diabetic Macular Edema Patients Unresponsive to Previous Anti-VEGF Therapy by Filipe Mira, Manuel Paulo, Filipe Henriques, João Figueira

“…The aim was to evaluate the efficacy of aflibercept in patients with diabetic macular edema (DME) unresponsive to prior anti-VEGF therapy. Methods. Retrospective review of DME unresponsive to previous anti-VEGF switched to aflibercept with 3 months of follow-up. …”
Get full text

Chloramphenicol-infused N-vinyl-based soft contact lenses for therapeutic and optical applications by Lina M. Shaker, Ahmed Alamiery, Abdulamier Ahmed Abdulamier, Wan Nor Roslam Wan Isahak

“…Key analysis including UV–Vis spectra, refractive index (RI) measurement, scanning electron microscopy (SEM) images, and Fourier-transform infrared (FTIR) charts confirmed the lenses’ physical, chemical, and therapeutic performance. The fabricated lenses demonstrated an impressive RI range of 1.49 to 1.53 preserving visual clarity and achieving over 95% visible light transmittance while effectively blocking UV radiation. …”
Get full text

FEATURES OF STUDENT SELF-IDENTIFICATION IN THE ERA AFTER THE "THERAPEUTIC TURN" by Elena S. Balashova, Anna V. Bogacheva, Anna V. Khizhnaya

Subjects: Get full text

Potential Therapeutic Drugs for Parkinson’s Disease Based on Data Mining and Bioinformatics Analysis by Chuan Xu, Jiajun Chen, Xia Xu, Yingyu Zhang, Jia Li

“…The objective is to search potential therapeutic drugs for Parkinson’s disease based on data mining and bioinformatics analysis and providing new ideas for research studies on “new application of conventional drugs.” …”
Get full text

Violences à l’acte, violences dans l’acte : pour une histoire des théâtres féministes états-uniens by Madeleine Planeix-Crocker

Subjects: Get full text

Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

“…In vitro and in vivo models confirmed that CBD inhibits AAI-induced upregulation of E2F1, thereby suppressing p53-mediated apoptosis. In conclusion, this study highlights the crucial role of E2F1 in AAI-induced renal cell apoptosis and identifies CBD as a novel therapeutic candidate for mitigating AAI nephrotoxicity.…”
Get full text

Examining the role of ClassPoint tool in shaping EFL students' perceived E-learning experiences: A social cognitive theory perspective by Huma Akram, Abbas Hussein Abdelrady

Subjects: Get full text

Genetic Hearing Loss and Gene Therapy by Nathanial T Carpena, Min Young Lee

Subjects: “…gene therapy…”
Get full text

Pulpal Thermal Changes following Er-YAG Laser Debonding of Ceramic Brackets by Didem Nalbantgil, Murat Tozlu, Mehmet Oguz Oztoprak

Get full text

An adenoviral vector encoding an inflammation-inducible antagonist, HMGB1 Box A, as a novel therapeutic approach to inflammatory diseases by Kari Ann Shirey, John Joseph, Lynda Coughlan, Haye Nijhuis, Alan W. Varley, Jorge C. G. Blanco, Stefanie N. Vogel

“…We hypothesized that gene therapy platforms could be useful in these cases if the production of an anti-inflammatory protein reflects the intensity and duration of the inflammatory condition. …”
Get full text

Theoretical and practical aspects of professional psychological selection of candidates for training at higher education institutions of the Ministry of Internal Affairs of Ukraine by A. V. Larionova

“…The author has offered a number of successive measures to solve them.…”
Get full text

A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets by Lin Li, Xin Zhang, Jiayao Yan, Jingyi Guo, Fangcen Liu, Xiao Wei, Qin Liu, Kongcheng Wang, Baorui Liu

Get full text