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38941
Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors
Published 2025-01-01“…In addition, MMPBSA/MMGBSA analysis confirmed the thermodynamic stability of each curcumin and CB[2]UN protein-ligand complex. …”
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38942
The Global Burden and Trends of Legionella spp. Infection-Associated Diseases from 1990 to 2021: An Observational Study
Published 2025-01-01“…Abstract Background Legionella infections are a major global health issue, yet there’s limited research on their impact and trends. …”
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38943
Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers
Published 2022-01-01“…Studies on osteomyelitis, wound therapy and management, multidisciplinary integration and mechanism of DFUs, and its related diseases are the research fronts that should be closely watched in the future. …”
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38944
METHODOLOGICAL ASPECTS OF THE DEVELOPMENT OF THE STRATEGY OF MACHINE-BUILDING ENTERPRISES IN THE RECOVERY FROM THE CRISIS
Published 2021-05-01“…The authors note the importance of the stages of checking the compliance of local goals with the overall economic strategy of the enterprise, as well as the use of strategic alternatives and the justification of the strategic choice based on them.…”
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38945
Emerging technologies of single-cell multi-omics
Published 2025-02-01“…These technologies have uncovered the intricate landscape of genetic clonality and transcriptional heterogeneity in both normal and malignant hematopoietic systems, highlighting their roles in differentiation, disease progression, and therapy resistance. This review aims to provide a brief overview of the principles of single-cell technologies, their historical development, and a subset of ever-expanding multi-omics tools, emphasizing the specific research questions that inspired their creation. …”
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38946
Outcomes of a Clinical Pathway for Pleural Disease Management: “Pleural Pathway”
Published 2018-01-01“…An administrative database was used for harvesting outcomes data and comparing them with the “prior to pathway” era. Results. 54 unique consults were performed. …”
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38947
Historical and legal overview of the State and Advocacy interaction within the system of human rights and freedoms protection
Published 2023-10-01“…The activities of the Advocacy have always been multifaceted, and therefore the article describes various methods of studying the interaction between the State and the Advocacy from the historical and legal perspective. …”
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38948
Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis
Published 2025-02-01“…Conclusion: Tyrphostin AG494 is the most effective natural phytochemical for inhibiting telomerase, exhibiting excellent binding affinity and stability, strong ADMET properties, and a safe toxicity profile. Therefore, following experimental validation, Tyrphostin AG494 is the most suitable and prospective candidate for telomerase inhibition and cancer therapy.…”
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38949
Temperature and Host Fruit During Immature Development Shape Adult Life History Traits of Different <i>Ceratitis capitata</i> Populations
Published 2025-01-01“…Larvae were reared on apples and bitter oranges at three constant temperatures (15, 20, and 25 °C), with pupae maintained under the same thermal conditions until adult emergence. Adults were then kept at 25 °C, with longevity and fecundity recorded daily. …”
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38950
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38951
Enviroshopping for Teens
Published 2012-09-01“…This revised 3-page fact sheet will help you make environmentally friendly choices whenever you make purchases and encourage you to take a second look at items before throwing them away. Written by Linda B. Bobroff and R. Elaine Turner, and published by the UF Department of Family, Youth and Community Sciences, September 2012. …”
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38952
An optimized approach for predicting water quality features and a performance evaluation for mapping surface water potential zones based on Discriminant Analysis (DA), Geographical...
Published 2025-01-01“…In addition, DA has been utilized to validate the result obtained from cluster analysis (CA), thereby facilitating the identification of the variables that distinguish the observed groups. …”
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38953
Velocity coefficient of tangential supply of subsonic centripetal turbine
Published 2022-06-01“…Today, in the spectrum of tasks solved by orbital spacecraft, there is a direction associated with an increase in both functional and thermal power radiated by the thermal control system into outer space. …”
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38954
The potential of fluorogenicity for single molecule FRET and DyeCycling
Published 2024-01-01“…DyeCycling addresses this problem by using reversibly – instead of covalently – coupled FRET fluorophores, through which it can break the photobleaching limit and theoretically provide unlimited observation time. In this perspective paper, we discuss the potential of various fluorogenic strategies to suppress the background fluorescence caused by unbound, freely diffusing fluorophores inherent to the DyeCycling approach. …”
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38955
Demystifying authenticity: Behavioral and neurophysiological signatures of self-positivity for authentic and presented selves
Published 2025-02-01“…Behaviorally, participants ascribed less positivity to the authentic self: They endorsed more negative traits and were faster to admit having them; also, they endorsed fewer positive traits and were slower to admit having them. …”
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38956
Chlamydia pneumoniae-Mediated Inflammation in Atherosclerosis: A Meta-Analysis
Published 2015-01-01“…Several studies have attempted to relate the C. pneumoniae-mediated inflammatory state with atherosclerotic cardiovascular diseases, providing inconsistent results. Therefore, we performed a meta-analysis to clarify whether C. pneumoniae may contribute to the pathogenesis of atherosclerosis by enhancing inflammation. 12 case-control, 6 cross-sectional, and 7 prospective studies with a total of 10,176 patients have been included in this meta-analysis. …”
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38957
Endothelial cells under disturbed flow release extracellular vesicles to promote inflammatory polarization of macrophages and accelerate atherosclerosis
Published 2025-01-01“…Conclusions Taken together, targeting the MAPK signaling pathway holds potential as a novel therapeutic strategy for inhibiting the secretion of EC-derived EVs and mitigating the inflammatory polarization of macrophages, ultimately ameliorating the progression of atherosclerosis. …”
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38958
A Novel Complex Valued Cuckoo Search Algorithm
Published 2013-01-01“…The value of independent variables for objective function is determined by modules, and a sign of them is determined by angles. The position of nest is divided into two parts, namely, real part gene and imaginary gene. …”
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38959
Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives
Published 2025-01-01“…It further discusses the application of gene therapy in conjunction with nanomedicine for targeted therapeutic interventions.…”
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38960
Investigation on the Hydrothermal Condition in Synthesis of Active Matrix from Metakaolin: Physicochemical Properties and Intrinsic Cracking Activities
Published 2024-10-01“…Subsequently, the active matrix was subjected to a series of analyses, including X-ray fluorescence, X-ray diffraction, N2 physisorption, NH3-temperature programmed desorption, Fourier transform infrared spectroscopy, scanning electron microscopy and thermogravimetry, with the objective of determining its composition, crystal characteristics, surface characteristics, acidity, functional groups, material structure, and thermal characteristics. …”
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