Evaluation of the psychometric properties of patient-reported outcome measures of health-related quality of life across the European cancer continuum: a systematic review protocol... by Nanne Bos, Galina Velikova, Giovanni Apolone, Gabriella Pravettoni, Mogens Groenvold, Gennaro Ciliberto, Augusto Caraceni, Hugo Vachon, Cinzia Brunelli, Morten Petersen, Claudio Lombardo, Ricardo Pietrobon, Alexandra Gilbert, Montserrat Ferrer, Morena Shkodra, Laurence Leysen, Madeline Pe, Karla Marticic Giljevic, Claire Piccinin, Norbert Couespel, Marianne Guren, Aude Sirven

“…The evaluation of the psychometric properties, data extraction and data synthesis will be conducted according to the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) methodology. …”
Get full text

Mechanistic insights into JSS1_004-mediated antagonism of the DndBCDE-FGH restriction system and engineering applications by Yu He, Susu Jiang, Fang Wang, Junwu Bi, Siting Li, Fuliang Yin, Shi Chen, Chao Chen, Lianrong Wang

“…These findings provide critical insights into the molecular arms race between phages and prokaryotic hosts while expanding the toolkit for developing phage-based biotechnological applications.…”
Get full text

Disability Inclusive Disaster Risk Reduction and Management: Assessing Vulnerabilities and Local Responses in Maasin City, Philippines by Kristoper Rex Oraiz, Elmee Joy Oraiz

“…Disability inclusive community-based disaster risk management: A toolkit. Handicap International. Harvard Humanitarian Initiative. (2023). …”
Get full text

Structure and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate by Angela Agnew, Ethan Humm, Kang Zhou, Robert P. Gunsalus, Z. Hong Zhou

“…There is a paucity of known enzyme structures from organisms of this domain, and this is often exacerbated by characteristically difficult growth conditions and a lack of readily available molecular biology toolkits to study proteins in archaeal cells. As a result, there is a gap in knowledge concerning the mechanisms governing archaeal protein behavior and their impacts on both the environment and human health; case in point, the synthesis of the widely utilized cofactor pyridoxal 5′-phosphate (PLP; a vitamer of vitamin B6, which humans cannot produce). …”
Get full text

Intersecting factors of disadvantage and discrimination and their effect on daily life during the coronavirus pandemic: the CICADA-ME mixed-methods study by Carol Rivas, Amanda P Moore, Alison Thomson, Kusha Anand, Zainab Zuzer Lal, Alison Fang-Wei Wu, Ozan Aksoy

“…We recognise the complexities and inadequacies of our categorisations, discussed in a study output (a toolkit). However, our intersectionality approach means these were starting points to be challenged and deconstructed. …”
Get full text

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Materials for patients included a toolkit (in written and video vignette form). Patients were also invited to a biweekly anonymous chat group. …”
Get full text