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4121
Fatal toxoplasmic encephalitis triggered by anti-TNF therapy
Published 2025-02-01“…First, in addition to her rheumatoid arthritis pathology, there is evidence of loss of immune resilience and abnormal T cell subsets. Second, some strains of T. gondii are more virulent than others. …”
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4122
Strength prediction of ECC-CES columns under eccentric compression using adaptive sampling and ML techniques
Published 2025-01-01“…SVR, CatBoost, and GPR models demonstrated mean μ, R2, and a20-index values near 1.0, with CoV and MAPE% values consistently low, indicating highly accurate predictions across testing subsets.…”
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4123
Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis
Published 2025-02-01“…Subgroup analysis was conducted on different AI subsets (Deep learning, and Machine learning). Results A total of 1606 studies were screened of which 25 studies were included. …”
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4124
L'abolition de la relégation en Guyane française (1938-1953)
Published 2014-09-01“…Un lent processus se met alors en place et aux relégués vont succéder des réfugiés d'Europe centrale, chargés en quelque sorte de prendre leur relève en Guyane, désormais département d'outre-mer depuis 1946.…”
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4125
Hybrid optimized artificial neural network using Latin hypercube sampling and Bayesian optimization for detection, classification and location of faults in transmission lines
Published 2024-11-01“…In terms of fault classification, the ANN model, trained on a dataset of 495 instances, revealed perfect regression coefficients across the training, testing, and validation subsets. When tested against unseen data, it demonstrated its proficiency by correctly classifying 154 out of 154 cases, showcasing a 100% F1 score. …”
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4126
Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici...
Published 2025-01-01“…For Kit-M, we noted optimal generation of DC-subsets at intermediary concentration ranges of PGE1 (0.25-4.0 µg/mL), which facilitated upregulation of activated and memory T-cells upon mixed lymphocyte culture, and efficient anti-leukemic activity in cytotoxicity assays. …”
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4127
Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis
Published 2025-01-01“…Intraperitoneal injection of B022 ameliorated the severity of EAMG rats, and reduced proportion of pathogenic B and T cell subsets, antibody levels and postsynaptic membrane damage. …”
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4128
Beliefs and outlook toward medications in Indian patients with very early rheumatoid arthritis: Cross sectional survey
Published 2020-01-01“…Methods: Two hundred and fifty patients fulfilling the American College of Rheumatology/European League against Rheumatism 2010 criteria for RA, who had developed arthritis within the past 3 months were surveyed using the Beliefs about Medicines Questionnaire (BMQ). For the BMQ subsets (specific necessity, specific concern, general overuse, and general harm), more than scale midpoint is considered high. …”
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4129
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept
Published 2025-01-01“…Peripheral blood mononuclear cells were isolated and analysed for T cell and B cell subsets by flow cytometry. Patients were genotyped for human leukocyte antigen (HLA)-DRB1 shared epitope (SE) alleles. …”
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4130
Monocyte and Macrophage in Follicular Liquid: Predictive Markers of Embryo Quality in Women with Obesity and Infertility
Published 2025-01-01“…The aim of this study was to assess the distribution of monocyte and macrophage subsets in the blood and follicular fluid of infertile women undergoing assisted reproductive technology. …”
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4131
Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production
Published 2025-01-01“…In contrast, it enhanced CIITA isoforms typically present in adaptive immune cell subsets. Restoring antigen presentation capacity of innate immune cells and early production of IFN-γ in LB patients may help re-establish immune functions during initial LB. …”
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4132
Comprehensive single-cell atlas of colorectal neuroendocrine tumors with liver metastases: unraveling tumor microenvironment heterogeneity between primary lesions and metastases
Published 2025-01-01“…We identified distinct cell subsets and receptor-ligand interactions that may drive TME discrepancies and support metastatic tumor growth. …”
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4133
Time-dependent, patient-centered perceptions of quality measures for total joint arthroplasty: a cross-sectional, choice modeling study
Published 2025-01-01“…Methods Patients who had undergone a TJA within the past two years or had a scheduled TJA within the next 6 months completed a questionnaire designed using best-worst scaling, a method used to measure individuals’ priorities by asking participants to make repeated selections of the best and worst items in a series of subsets of items. Subanalyses were calculated to compare each phase of care (preoperative, short term postoperative, and long term postoperative). …”
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4134
Socio-economic inequality in the nutritional deficiencies among the world countries: evidence from global burden of disease study 2019
Published 2025-01-01“…Methods Burden data of nutritional deficiencies and its subsets including protein-energy malnutrition, iodine deficiency, vitamin A deficiency, and dietary iron deficiency form GBD study and Human Development Index (HDI), a proxy for the socio-economic status of countries, from united nations database were collected. …”
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4135
The Accuracy of the NSQIP Universal Surgical Risk Calculator Compared to Operation-Specific Calculators
Published 2023-12-01“…Operation-specific risk calculators (OS-RC) and OS-RCs with operation-specific predictors (OSP-RC) were independently developed for each of 6 operative groups (colectomy, whipple pancreatectomy, thyroidectomy, abdominal aortic aneurysm (open), hysterectomy/myomectomy, and total knee arthroplasty) and 14 outcomes using the same 80%/20% rule applied to the appropriate subsets of the 5M records. Predictive accuracy was evaluated using the area under the receiver operating characteristic curve (AUROC), the area under the precision-recall curve (AUPRC), and Hosmer-Lemeshow (H-L) P values, for 13 binary outcomes, and mean squared error for the length of stay outcome. …”
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4136
STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease
Published 2019-01-01“…Crohn’s disease (CD) results from dysregulated immune responses to gut microbiota in genetically susceptible individuals, affecting multiple areas of the gastrointestinal tract. …”
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4137
Explainable artificial intelligence in web phishing classification on secure IoT with cloud-based cyber-physical systems
Published 2025-01-01“…Furthermore, the Harris' Hawks optimization-based feature selection (HHO-FS) method is applied to derive feature subsets. The XAIAOA-WPC method utilizes a multi-head attention-based long short-term memory (MHA-LSTM) model for web phishing recognition. …”
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4138
Predictors for abundance of host flea and floor flea in households of villages with endemic commensal rodent plague, Yunnan Province, China.
Published 2011-03-01“…<h4>Results</h4>A total of 344 fleas were collected on 101 small mammals (94 Rattus flavipectus and 7 Suncus murinus). R. flavipectus had higher flea prevalence and abundance than S. murinus, but the flea intensities did not differ significantly. …”
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4139
Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses
Published 2020-01-01“…Besides, we detected the relative fraction of 22 immune cell types in atherosclerosis by using the deconvolution algorithm of “cell type identification by estimating relative subsets of RNA transcripts (CIBERSORT).” Ultimately, based on the significantly changed types of immune cells, we executed the correlation analysis between DEGs and immune cells to discover the potential genes and pathways associated with immune cells. …”
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4140
Wrong Answers Only: Distractor Generation for Russian Reading Comprehension Questions Using a Translated Dataset
Published 2024-12-01“…The models were assessed automatically on test and development subsets, and true statement distractor models were additionally evaluated on an independent set of questions from Russian state exam USE. …”
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