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4061
A multivalent binding model infers antibody Fc species from systems serology.
Published 2024-12-01“…Finally, we use the model to identify redundant assay measurements and subsets of information-rich measurements from which Fc properties can be inferred. …”
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4062
Investigating male factors and their relationships with reproductive health outcomes: a case-control study protocol for Towards Optimal Fertility, Fathering, and Fatherhood studY (...
Published 2025-01-01“…We will construct a logistic regression model incorporating both male and female factors to derive a fertility index, which will be evaluated using cross-validation on subsets of the study population. Multivariable linear regression will be used to explore relationships between male modifiable exposures and semen parameters.Ethics and dissemination The study protocol has received approval from the Centralised Institutional Review Board of SingHealth (2024/2120), Singapore. …”
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4063
Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024)
Published 2025-01-01“…Results: The final consensus included 15 statements covering major TN CLL patient subsets. The recommendations highlight the importance of molecular testing for key biomarkers, where available/accessible, to guide initial therapy. …”
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4064
Transcriptional regulatory network analysis identifies GRN as a key regulator bridging chemotherapy and immunotherapy response in small cell lung cancer
Published 2025-02-01“…GRN and its associated genes were linked to cancer cell intrinsic immunogenicity, and single-cell RNA-seq data revealed that GRN expression is particularly high in subsets of tumor-associated macrophages. In concordance with these findings, GRN-low tumors showed significantly better survival with chemo-immunotherapy, while GRN-high tumors did not benefit from additional immunotherapy. …”
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4065
Exhaled Nitric Oxide in Systemic Sclerosis Lung Disease
Published 2017-01-01“…We evaluated the discriminative validity, feasibility, methods of eNO measurement, and magnitude of differences across lung diseases, disease-subsets (SSc, systemic lupus erythematosus), and healthy-controls. …”
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4066
Establishment and Validation of a Machine‐Learning Prediction Nomogram Based on Lymphocyte Subtyping for Intra‐Abdominal Candidiasis in Septic Patients
Published 2025-01-01“…We assessed the clinical characteristics and lymphocyte subsets at the onset of IAI. A machine‐learning random forest model was used to select important variables, and multivariate logistic regression was used to analyze the factors influencing IAC. …”
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4067
Optimal Topology Management for Software-Defined Networks Minimizing Latency and Using Network Slicing
Published 2024-01-01“…The second one consists of subsets of users separated within each slice requirement. …”
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4068
A multi-patch-based deep learning model with VGG19 for breast cancer classifications in the pathology images
Published 2025-01-01“…Current techniques rely on quantifying gene expression in limited subsets. Given the complexity of breast tissues, effective detection and classification of breast cancer is crucial in medical imaging. …”
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4069
Quantitative Attribution Analysis of the Spatial Differentiation of Gully Erosion in the Black Soil Region of Northeast China
Published 2022-01-01“…The results showed that at the large catchment scale, the submeter images had a strong capacity for the recognition of a permanent gully and obtained satisfactory results. …”
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4070
Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy
Published 2025-02-01“…Our analysis identified four predominant subsets: C0 IER2+, C1 ABCA8+, C2 ABI3BP+, and C3 MEOX2+. …”
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4071
An Approach for Detecting Parkinson’s Disease by Integrating Optimal Feature Selection Strategies with Dense Multiscale Sample Entropy
Published 2024-12-01“…K-fold cross-validation was employed to provide improved evaluation of model performance by assessing the model on various data subsets, thereby mitigating the risk of overfitting and augmenting the robustness of the results. …”
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4072
A Hybrid Model for Psoriasis Subtype Classification: Integrating Multi Transfer Learning and Hard Voting Ensemble Models
Published 2024-12-01“…The feature set was divided into 80% training and 20% testing subsets and evaluated using a hard voting classifier consisting of logistic regression, random forest, support vector classifier, k-nearest neighbors, and gradient boosting algorithms. …”
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4073
CORRELATION BETWEEN EFL STUDENTS’ PERCEIVED LINGUISTIC PROFICIENCY AND THEIR LEVEL OF CONFIDENCE IN USING ENGLISH
Published 2019-06-01“…To confirm where the differences lie, Post Hoc tests (Turkey HSD and Homogeneous Subsets) were used. NOVA gives an F value of 44.131 with 2 and 57 degrees of freedom (p < 0.01), showing that there are differences in self-assessment means among groups. …”
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4074
Characterization of Transverse Aortic Constriction in Mice Based on the Specific Recruitment of Leukocytes to the Hypertrophic Myocardium and the Aorta Ascendens
Published 2021-01-01“…We used complex flow cytometry staining combinations to characterize the various innate immune cell subsets and a multiplex array to determine cytokine concentrations in the serum. …”
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4075
Functional Tests and Surveys Used to Assess Nervous System Dysfunction in Patients with Fabry Disease – A Review
Published 2025-01-01“…Conclusions: The findings of this review suggest that while autonomic dysfunction may be present in certain subsets of FD patients. Functional tests revealed limited evidence of widespread autonomic dysfunction. …”
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4076
Immunomodulatory Potential of Piperine in Rats
Published 2024-04-01“…In a separate set of experiments, the effects of piperine gavage on T helper lymphocyte responses in vivo and ex vivo and their subsets were performed in animals challenged with ovalbumin (OVA). …”
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4077
Nuclear DNA Content and Chromatin Pattern of Rat Rhabdomyosarcoma Cell Sublines with Different Metastatic Potentials
Published 2000-01-01“…These results were confirmed by an unsupervised multivariate partitioning of rhabdomyosarcoma cells which identified two separate subsets whose distributions within the analyzed cell lines correlate with their metastatic ability. …”
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4078
Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Published 2025-01-01“…Results We observed a significant reduction in CD8αα + IELs, accompanied by a marked increase in CD8αβ + IELs in Lpr mice. Additionally, subsets of CD8 + IELs exhibiting significantly enhanced effector functions were found to be markedly enriched in Lpr mice. …”
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4079
Automatic detection of floating instream large wood in videos using deep learning
Published 2025-02-01“…We designed multiple scenarios using different data subsets with and without data augmentation. We analysed the contribution of each scenario to the effectiveness of the model using <span class="inline-formula"><i>k</i></span>-fold cross-validation. …”
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4080
Correlation between vitamin D levels, individual and socio-demographic characteristics and COVID-19 infection and death rates in 20 European countries: A modelling study
Published 2020-12-01“…Data distributions were normalised by the Box and Cox approach and the Minitab routine ‘Best Subsets’ was used to select the best descriptor sets for each quantitative model of cases and deaths. …”
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