Clinical characteristics, therapeutics, and treatment outcomes of adult patients with anti-melanoma differentiation-associated gene 5 dermatomyositis: A single-center experience fr... by Shivraj Padiyar, Aswin M Nair, Bijesh Yadav, Prathyusha Manikuppam, Jha Avanish, Abhilasha Arvind Manwatkar, John Mathew

“…Conclusions: Anti-MDA5 DM represents a distinct and unique subset of IIM with characteristic clinical manifestations. …”
Get full text

LoSI: Large Scale Location Inference Through FM Signal Integration and Estimation by Tathagata Mukherjee, Piyush Kumar, Debdeep Pati, Erik Blasch, Eduardo Pasiliao, Liqin Xu

“…The system first runs a DCD feature detector on the observed spectrum and then solves a subset query formulation to find Inference Candidates (IC). …”
Get full text

Long-term effects of SARS-CoV-2 infection and vaccination in a population-based pediatric cohort by Jakob Höppner, Christoph Maier, Anne Schlegtendal, Anna Hoffmann, Astrid Petersmann, Thomas Lücke, Nicole Toepfner, Folke Brinkmann

“…The overall health status was comparable between children, irrespective of SARS-CoV-2 infections and similar to pre-pandemic assessment. However, a subset of young adolescents exhibited a decline in physical performance compared to pre-pandemic conditions. …”
Get full text

RETRACTED ARTICLE: NR3C2 affects the proliferation and invasiveness of colon cancer cells through the Wnt/β-Catenin signaling pathway by Ke Nie, Zhong-Jiang He, Ling-Jun Kong

“…Single-cell transcriptome data identified the subset of circulating T and B cells with high expression of NR3C2, which is involved in TNF signaling pathway. …”
Get full text

First-in-Men Online Adaptive Robotic Stereotactic Body Radiation Therapy: Toward Ultrahypofractionation for High-Risk Prostate Cancer Patients by Victor J. Brand, MD, Maaike T.W. Milder, PhD, Miranda E.M.C. Christianen, MD, PhD, Kim C. de Vries, MD, Mischa S. Hoogeman, PhD, Luca Incrocci, MD, PhD, Femke E. Froklage, MD, PhD

“…Purpose: Ultrahypofractionation presents challenges for a subset of high-risk prostate cancer patients due to the large planning target volume (PTV) margin required for the seminal vesicles. …”
Get full text

PDPN+ cancer‐associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF‐κB activation and the CCL2‐ACKR1 axis by Zhenxiong Zhao, Hui Sun, Yingxue Liu, Yanqiu Zhang, Xin Wang, Xu Wang, Cong Tan, Shujuan Ni, Weiwei Weng, Meng Zhang, Lei Wang, Dan Huang, Wenchao Gu, Jinjia Chang, Weiqi Sheng, Mi‐die Xu

“…Through an unbiased integrated analysis of gastric tumor grade and stage, we identified a subset of proangiogenic CAFs characterized by high podoplanin (PDPN) expression, which are significantly enriched in metastatic lesions and secrete chemokine (CC‐motif) ligand 2 (CCL2). …”
Get full text

ABCD3-I and ABCD2 Scores in a TIA Population with Low Stroke Risk by Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Hild Fjærtoft, Bent Indredavik

“…We performed a prospective, multicenter study in Central Norway from 2012 to 2015, enrolling 577 patients with TIA. In a subset of patients with complete data for both scores (n=305), we calculated the AUC statistics of the ABCD3-I score and compared this with the ABCD2 score. …”
Get full text

Looking at Infrared Background Radiation Anisotropies with Spitzer: Large-scale Anisotropies and Their Implications by A. Kashlinsky, Richard G. Arendt, M. L. N. Ashby, J. Kruk, N. Odegard

“…The maps are constructed using the self-calibration methodology eliminating artifacts to sufficient accuracy, and subset maps are selected in each area containing approximately uniform exposures. …”
Get full text

New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness by Giuseppe Spaziano, Donato Cappetta, Konrad Urbanek, Elena Piegari, Grazia Esposito, Maria Matteis, Manuela Sgambato, Gioia Tartaglione, Rosa Russo, Raffaele De Palma, Francesco Rossi, Antonella De Angelis, Bruno D’Agostino

“…In MSC-treated mice, the macrophage polarization to M2-like subset may explain, at least in part, the increment in the level of anti-inflammatory cytokine IL-10. …”
Get full text

Altered circadian rhythmicity of the QT interval predicts mortality in a large real-world academic hospital population by Rutger R. van de Leur, Bastiaan C. du Pré, Markella I. Printezi, Rutger J. Hassink, Pieter A. Doevendans, René van Es, Linda W. van Laake

“…An individual 24-h QT interval amplitude was obtained from the model in a subset with patients that had at least 3 ECGs of which one during the night before their last ECG. …”
Get full text

Neden, Süreç ve Sonuçlarıyla Dinsel Değişim: Yaşar Alptekin Örneği by Asım Yapıcı, İbrahim Yıldırım

“…Tarihsel süreçten bugüne kadar olumlu veya olumsuz biçimde neredeyse tüm insanların muhtelif boyutlarda dinsel unsurlar ile temas ediyor oluşu, dinsel değişim konusunu akademik alanda önemli ve güncel tutan hususlardandır. Bu çalışma; inançlı olduğu hâlde dine karşı ilgisiz bir hayat sürdüren Yaşar Alptekin’in neden ve nasıl dindarlaştığı sorusuna cevap aramaktadır. …”
Get full text

Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999–2019: the EPIC-Norfolk cohort by Kay-Tee Khaw, Robert Luben, Shabina Hayat, Nicholas Wareham, Paul P Pharoah

“…Age per 10-year increase (OR 2.19, 95% CI 2.06 to 2.33) and male sex (OR 1.32, 95% CI 1.19 to 1.47) predicted incident multimorbidity over 10 years. In the subset free of the most serious diseases at baseline, current smoking (OR 1.86, 95% CI 1.60 to 2.15), body mass index >30 kg/m² (OR 1.48, 95% CI 1.30 to 1.70) and physical inactivity (OR 1.16, 95% CI 1.04 to 1.29) were positively associated and plasma vitamin C (a biomarker of plant food intake) per SD increase (OR 0.86, 95% CI 0.81 to 0.91) inversely associated with incident 10-year multimorbidity after multivariable adjustment for age, sex, social class, education, alcohol consumption, systolic blood pressure and cholesterol. …”
Get full text

Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

“…Feasibility variables, patient-reported outcomes and clinical findings measured at baseline, 3 and 9 months will be assessed and integrated with qualitative interview data from a subset of Group E-Rehab and My Knee UK participants. …”
Get full text

18F-FDG PET/CT assessment of metabolic tumor burden predicts survival in patients with metastatic posterior uveal melanoma by Tine Gadegaard Hindso, Torben Martinussen, Camilla Wium Bjerrum, Sune Høgild Keller, Annika Loft, Mette Bagger Sjøl, Kristoffer Nissen, Carsten Faber, Marco Donia, Inge Marie Svane, Eva Ellebaek, Steffen Heegaard, Jens Folke Kiilgaard, Karine Madsen

“…Time-dependent positive predictive value (PPV) analysis and Receiver Operating Characteristics (ROC) curves showed that MTV (Area Under the Curve (AUC) = 0.78), TLG (AUC = 0.78), and LDLM (AUC = 0.76) were good predictors of 1-year survival. For the subset of 97 patients with liver metastases, the corresponding regional measurements in the liver tended to be even better predictors. …”
Get full text

Exploring the heterogeneity of HER2 gene status and expression in non-positive breast cancer patients: insights from immunohistochemistry and fluorescence in situ hybridization by Jingmin Zhong, Beibei Gao, Qingjie Wang, Jun He, Danjv Luo, Chen Zhang, Jun Fan, Xiu Nie

“…Further studies are needed to improve HER2 assessment in this challenging subset of patients.…”
Get full text

Geospatial Data and Deep Learning Expose ESG Risks to Critical Raw Materials Supply: The Case of Lithium by Christopher J. M. Lawley, Marcus Haynes, Bijal Chudasama, Kathryn Goodenough, Toni Eerola, Artem Golev, Steven E. Zhang, Junhyeok Park, Eleonore Lèbre

“…., >10 Mt Li2O) are restricted to regions with higher spatially situated risks relative to a subset of smaller pegmatite-hosted deposits that yield higher ESG ratings (i.e., lower risk). …”
Get full text

Postmodern Çağ ve Sosyal Medya: Beğeni Toplumunun Panoraması by Muhammed Yamaç

“…Bu araştırma, söz konusu problematiği ele almayı ve güncel durumu sosyolojik olarak gözler önüne sermeyi amaçlamaktadır. …”
Get full text

Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility by Carmelo Scarpignato, Iva Pelosini

“…Indeed, transit and contractile abnormalities have been demonstrated with sophisticated techniques in a subset of patients with IBS. As a consequence, drugs affecting gastrointestinal (GI) motility have been widely employed with the aim of correcting the major IBS manifestations, ie, pain and altered bowel function. …”
Get full text

Neslin Korunması İlkesi Bağlamında “Toplumsal Cinsiyet ve Cinsiyetsizlik” Söylemlerine Eleştirel Bakış by Meryem Cihangir

“…Bu çalışma ile cinsiyet temelli güncel tartışmaların dayanak noktalarının tespiti sağlanmıştır. …”
Get full text

Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition by Zsolt Tamás Papp, Polett Ribiczey, Erzsébet Kató, Zsuzsanna E. Tóth, Zoltán V. Varga, Zoltán Giricz, Adrienn Hanuska, Mahmoud Al-Khrasani, Ákos Zsembery, Tibor Zelles, Laszlo G. Harsing, László Köles

“…NMDA (30 μM) induced stable inward cation currents, significantly inhibited by Ang IV (1 nM–1 µM) in a subset of pyramidal neurons. This inhibition was reproduced by the IRAP inhibitor LVVYP-H7 (10–100 nM). …”
Get full text