Development and model test of dynamic loading system in mine goaf site for high-speed railway subgrade by Lianwei REN, Liang LI, Ziqiang WANG, Youfeng ZOU, Zhilin DUN, Shuren WANG

“…The activation of the collapse fault zone further impacts the stress distribution in the overlying rock above the main key layer and causes an uneven settlement on the model surface. This results in the formation of three types of cracks (transverse, vertical, and inclined) in the bending deformation zone, which are distributed along both sides of subgrade.…”
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A New Nanocomposite for Inducing Demineralized Dentin Remineralization by Ban G, Long J, Yan K, Li Q, Huang X, Wei X, Xie F

“…The SEM results indicated that the PAMAM-COOH/ACMP-MDP group exhibited distinct characteristics of collagen fiber remineralization, both on the surface and within the deep dentin tubules. The collagen fibers in this group were thicker and more mineralized. …”
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Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study by Zucca G, Vigani B, Valentino C, Ruggeri M, Marchesi N, Pascale A, Giovilli G, Malavasi L, Sandri G, Rossi S

“…Gaia Zucca,1 Barbara Vigani,1 Caterina Valentino,1 Marco Ruggeri,1 Nicoletta Marchesi,1 Alessia Pascale,1 Giulia Giovilli,2 Lorenzo Malavasi,2 Giuseppina Sandri,1 Silvia Rossi1 1Department of Drug Sciences, University of Pavia, Pavia, 27100, Italy; 2Department of Chemistry and INSTM, University of Pavia, Pavia, 27100, ItalyCorrespondence: Silvia Rossi; Barbara Vigani, Department of Drug Sciences, University of Pavia, Via Taramelli 12, Pavia, 27100, Italy, Email silvia.rossi@unipv.it; barbara.vigani@unipv.itPurpose: The main purpose of the study was the formulation development of nanogels (NHs) composed of chondroitin sulfate (CS) and low molecular weight chitosan (lCH), loaded with a naringenin-β-cyclodextrin complex (NAR/β-CD), as a potential treatment for early-stage diabetic retinopathy.Methods: Different formulations of NHs were prepared by varying polymer concentration, lCH ratio, and pH and, then, characterized for particle size, zeta potential, particle concentration (particles/mL) and morphology. …”
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Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis by Xiang F, Zhang Z, Nie Y, Cao X, Li Y, Chen X, Gong S, Zou J, Teng J, Ding X, Shen B

“…The enzyme CD73, a cell surface 5′-nucleotidase, regulates the balance between pro-inflammatory nucleotides and anti-inflammatory adenosine. …”
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A novel nanomaterial baffle decrease aerosols and microbial aerosols during non-contact tonometry measurements by X. Shen, Y. Guo, X, X. Wang, Y. Ye, Q. Chi, W. Zhou, Y. Chen, C. Li

“…</p> <p> <b>Conclusion: </b>Aerosolized ocular surface microorganisms (AOSM) can spread by human eyes NCT measured, pathogens may among them. …”
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Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

“…This study investigated the role of gut microbiota related bile acid metabolism in colonic inflammation in both patients with inflammatory bowel disease (IBD) and a murine model of dextran sulfate sodium (DSS)-induced colitis. Methods Bile acids in fecal samples from patients with IBD and DSS-induced colitis mice, with and without antibiotic treatment, were analyzed using ultraperformance liquid chromatography-mass spectrometry (UPLC-MS). …”
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An efficient method for predicting the morphology of proppant packs based on a surrogate model by Tao ZHANG, Hangyu ZHOU, Yifan ZHANG, Jianchun GUO, Haoran GOU, Tang TANG

“…For the displacement-height model, although the predicted placement profile lacked detailed irregularities of the proppant accumulation surface because of model simplification, it accurately described the characteristic variation in placement morphology with changes in injection rate, demonstrating that the surrogate model for predicting particle placement height can also efficiently capture the proppant placement morphology within the fracture. …”
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Role of Cylindrospermopsis sp. in vertical nitrogen changes observed in tropical oxidation wastewater treatment ponds by M. Srichomphu, O. Phewnil, T. Pattamapitoon, Ratcha Chaichana, K. Chunkao, W. Wararam, N. Dampin, P. Maskulrath

“…This study focuses on the vertical distribution of the phytoplankton Cylindrospermopsis sp. and its relationship with nitrogen compounds in oxidation ponds.METHODS: Samples were collected from a community wastewater treatment system at various depths (30, 60, 90, 120, and 150 centimeters) below the water surface in April 2019 between 11:00 and 13:00 hours and analyzed for their chemical and physical properties. …”
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Effects of Yanghe Decoction on IL-1 and TNF-α of Papain in Rabbit Knee Osteoarthritis by Zhenqiang HONG, Hongjian GAO, Junjun HE, Zeling HUANG

“…The levels of interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) in serum and synovial fluid were detected by enzyme-linked immunosorbent assay (ELISA).Results:Compared with the control group, the model group's cartilage surface was uneven and local defects, the morphology and structure of cartilage was disordered, the number of chondrocytes decreased, the tidal line disorder disappeared, the Mankin's score increased, and the contents of IL-1 and TNF-α in serum and synovial fluid increased, and the difference was statistically significant (<italic>P</italic>&lt;0.05). …”
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Preindustrial-to-present-day changes in atmospheric carbon monoxide: agreement and gaps between ice archives and global model reconstructions by X. Faïn, S. Szopa, V. Naïk, P. Martinerie, D. M. Etheridge, D. M. Etheridge, R. H. Rhodes, C. M. Trudinger, C. M. Trudinger, V. V. Petrenko, K. Fourteau, P. Place, P. Place

“…In this study, we compare the simulated atmospheric surface CO mixing ratios ([CO]) from two different sets of chemistry–climate models and emissions within the frameworks of CMIP5 and of CMIP6 (Coupled Model Intercomparison Project Phases 5 and 6) to recent bipolar ice archive reconstructions for the period spanning 1850 to the present. …”
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Effect of Extracorporeal Shock Wave combined with Rehabilitation Training on Patients with Chondromalacia Patellae by Yanna ZHU, Yupeng LIU, Xiaoyi FAN, Chunling LIU, Hui YU, Xin QI, Shunji SHEN

“…During the pulse, the patella was pushed to the opposite side, so that the shock wave could reach the cartilage surface of the patella as far as possible. The pulse at each point was 300 times, one time a week, continuous treatment for eight weeks. …”
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Efficacy of dietary supplementation with 1α-hydroxycholecalciferol on performance, eggshell quality, serum metabolites, jejunal morphology and bone characteristics of laying hens a... by Maryam Ghaderi Nik, Reza Mahdavi, Shahab Ghazi, Kourosh Gholami

“…The experimental treatments did not affect the jejunal villus height, villus width and villus surface area in aged laying hens (P > 0.05). Our findings suggest that the inclusion of 1αOHD3 is beneficial, as it enhances egg production, profitability, eggshell thickness, and tibia quality while reducing the incidence of abnormal eggs during the later phase of egg production.…”
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瓜蒌籽甘油二酯油的酶法甘油解制备研究 "reparation of diacylglycerol from Trichosanthes kirilowii seed oil by enzymatic glycerolysis" by 周子旋，苏菁菁，韩艳萍，丁晓凡，江濛，王莉，薛秀恒 " ZHOU Zixuan, SU Jingjing, HAN Yanping, DING Xiaofan, JIANG Meng, WANG Li, XUE Xiuheng"

“…The reaction conditions were optimized by response surface methodology. The lipid composition, fatty acid composition and basic physicochemical indexes of Trichosanthes kirilowii oil before and after enzymatic glycerolysis were analyzed. …”
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Computational and theoretical studies of nodal joints in monolithic buildings by T. A. Belash, A. V. Kuznetsov

“…It was determined that in the cold period of the year, in heated buildings of the type under consideration, the destruction of the protective layer of concrete occurs in the zone of alternating temperature effects, which leads to the fact that in the perforated floor slab, the nature of the multi-cycle temperature effects forms the appearance of cracks and destruction of concrete on the side surfaces of the keys. The results of numerical simulation showed that under the action of negative outdoor temperatures, the greatest stresses occur at the junctions of perforations with keys and exceed the standard values of the calculated stress by 1.4 times. …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Melanoma cells containing an IFN-γ receptor (IFNγR) cytoplasmic domain deletion mutant was overexpressed and used for characterization of the metabolic profile of those tumor cells using a Seahorse Flux Analyzer.Results Met administration elevates mtROS and cell surface Glut-1, resulting in the production of IFN-γ in CD8TILs. mtROS activates Nrf2 in a glycolysis-dependent manner, inducing activation of autophagy, glutaminolysis, mTORC1, and p62/SQSTM1. mTORC1-dependent phosphorylation of p62 at serine 351 (p-p62(S351)) is also involved in activation of Nrf2. …”
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Photoelectrochemical characterization and photocatalytic properties of mesoporous <mml:math alttext="${{{ext{TiO}}_{ext{2}} } mathord{left/ {vphantom {{{ext{TiO}}_{ext{2}} } {{ext...

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IOP-lowering effect and tolerability of prostaglandin analogues in primary open-angle glaucoma and ocular hypertension as risk factors for glaucoma progression by A.V. Belogurova, E.N. Eskina, Zh.G. Oganezova

“…Tafluprost has also good tolerability in terms of improved subjective complaints and signs of dry eye as well as objective ocular surface criteria. Switching from preservative-containing tafluprost to preservative-free formulation is reasonable and can improve compliance due to its efficacy.…”
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Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus by YU Qin, XU Tingting, YANG Hao, ZHAO Lei

“…[Methods] From January to December 2022, 219 samples positive for hepatitis B surface antigen (HBsAg), 142 occult hepatitis B virus infection (OBI) samples (HBV group) and 873 samples tested negative (control group) were collected. 361 samples were further tested with viral load assay and serological testing for five serological markers (HBsAg, HBsAb, HBeAg, HBeAb and HBcAb), and the DNA load was measured using real time fluorescence quantitative PCR. …”
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Quantifying diversity and growth form distribution of scleractinian corals, in Mangrove Bay, El Qoseir, Egypt by Theres Koch, Angelina Ivkić, Lewis Jones, Victor Scharnhorst, Constanze Stix, Antonia Auer, Theda Schöchtner, Gözde Özer, Simon Steinwender, Joseph Wallace Daurella, Martin Zuschin

“…These rich ecosystems are becoming increasingly degraded in many regions by a range of anthropogenic factors, including recurrent bleaching episodes associated with rising sea surface temperatures. Within the northern Red Sea, coral reef communities appear to be faring relatively better than global trends and continue to exhibit remarkable diversity and thermal tolerance. …”
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Educational effectiveness of cognitive and metacognitive strategies on educational self-destructive behaviors and negative self-evaluation thinking in Arabic lessons by Ali Nourihamid Altome, Mohammad hassani, Masoumeh Talebi

“…Besides, the process of teaching Arabic language has neglected the psychological issues of language teaching, cognitive and metacognitive elements such as motivation, excitement, intelligence, etc., and only sufficed to present texts for understanding and dialogue for a transient an deficient interaction (Azarshab & Homayuni 2015), as a result, we see educational self-defeating behaviors under the influence of self-evaluation thoughts, not negative, in learning Arabic among students. …”
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