Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome by Sara E.L. Tolouei, Rodrigo Marcon, Fabiana Cardoso Vilela, Cristina Setim Freitas, Melina Heller, Edineia Lemos de Andrade, Sergio José Macedo Júnior, Adara Áurea dos Santos, Ruth Fernandes Rocha, Guilherme Pasetto Fadanni, Naiani Ferreira Marques, Jarbas Mota Siqueira Júnior, João B. Calixto

“…Finally, TI-076 did not interact with CYP3A4 in vivo and proved to be safe. These findings strongly suggest that TI-076 holds great potential for clinical trials aimed at developing a safe phytomedicine for treating obesity and related metabolic diseases.…”
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Conceptual Approaches to the Problem of national Security Concept by Yu. O. Zahumenna

“…Obviously, such activity of the non-governmental sector should be strongly encouraged by legislative instruments, legitimizing measures for national security reform through its close involvement and providing them with additional public support.…”
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Resistance training beyond momentary failure: the effects of past-failure partials on muscle hypertrophy in the gastrocnemius by Stian Larsen, Paul Alan Swinton, Nordis Østerås Sandberg, Benjamin Sandvik Kristiansen, Andrea Bao Fredriksen, Hallvard Nygaard Falch, Roland van den Tillaar, Milo Wolf

“…The results identified an ATE favouring the inclusion of additional partial repetitions (0.62 [95%CrI: 0.21–1.0 mm; p(>0) = 0.998]) with ‘strong’ evidence (BF = 13.3) supporting a priori hypothesis. …”
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Indoor and Outdoor Exposure to PM2.5 during COVID-19 Lockdown in Suburban Malaysia by Eliani Ezani, Peter Brimblecombe, Zulfa Hanan Asha’ari, Amirul Aiman Fazil, Sharifah Norkhadijah Syed Ismail, Zamzam Tuah Ahmad Ramly, Md Firoz Khan

“…Abstract During the COVID-19 pandemic, key policies aimed at reducing exposure to the virus from social distancing, restrictions on travel through to strongly enforced lockdowns. However, COVID-19 restrictions required people to spend more time at home so the exposure to air pollutants shifted to being derived from that of domestic interiors, rather than outdoors or the workplace environment. …”
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Hydrogeology and Hydrogeochemistry of the Lauria Mountains Northern Sector Groundwater Resources (Basilicata, Italy) by Filomena Canora, Giovanna Rizzo, Simona Panariello, Francesco Sdao

“…The analyses highlight that the chemical compositions of groundwater are strongly influenced by the lithology, especially limestones and dolomitic limestones; they explain and confirm the hydrogeological setting of the system. …”
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A Cell Differentiation Trajectory-Related Signature for Predicting the Prognosis of Lung Adenocarcinoma by Fan Yang, Yan Zhao, Xiaohan Huang, Jin Zhang, Ting Zhang

“…Moreover, a nomogram was constructed based on the prognostic signature and clinicopathological features, and this nomogram had strong predictive performance and high accuracy. Conclusion. …”
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Design, synthesis and evaluation of benzofuran-acetamide scaffold as potential anticonvulsant agent by Shakya Ashok K., Kamal Mehnaz, Balaramnavar Vishal M., Bardaweel Sanna K., Naik Rajashri R., Saxena Anil K., Siddiqui H. H.

“…The pharmacophore mapping of the examined compounds on standard drugs (phenobarbital, phenytoin, ralitolin and carbamazepine) strongly suggests that these compounds may exert their anticonvulsant activity via the same established mechanism as that of known drugs.…”
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The effect of cervical spine flexion-extension motion on odontoid parameters by Longao Huang, Dun Liu, Hongyuan Xu, Junfei Feng, Tao Kang, Shengwang Wei, Hua Jiang

“…Results No significant differences were found for OI and T1S among the three different cervical spine positions (p = 0.162 and p = 0.186, respectively). There was a strong, significant positive correlation between the predicted value and actual value of physiological CL at three cervical positions (neutral, flexion, and extension). …”
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Foliar image-based characterization of airborne particulate matter in an urban area and its implications for remediation by Ankesh Tiwari, Triratnesh Gajbhiye, Mohineeta Pandey, Kajal Agrawal, Shuvadarshini Naik, Shubhrasmita Meher, Dinesh Patel, Rashmi Dubey, Tanzil Gaffar Malik, Mohammed Zari, Ali Zari, Khalid M Alghamdi, Khalid Rehman Hakeem, Sudhir Kumar Pandey

“…Notably, the smaller leaves of Senna siamea and Dalbergia sissoo prevent PM from being resuspended in the air by strong winds, enhancing their overall performance in combating PM pollution. …”
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Macroanatomic studies on the stomach of camel by Hasan Erden, M. Kamil Öcal, Necdet Güzel, Erkut Kara, İlknur Öğüt

“…Intemally the glandular sacs consist of smaller compartments divided by strong longitudinal bands and most of these compartments are again sub-divided by transverse bands, thus giving them a honey comb appearance. …”
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Structural Performance of Reinforced Concrete Beams with Steel Fibres as Secondary Reinforcement: Experimental and Pre-peak Numerical Modelling by Hadjer Belkadi, Abdelkrim Bourzam, Messaoud Saidani

“…The model, which does not explicitly simulate steel fibres, was validated against experimental data, showing strong agreement and confirming its effectiveness in capturing the flexural behaviour of steel fibre reinforced concrete beams. …”
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Biodiversity and specificity of planktonic ciliate communities from the zone of Volga and Kama Rivers confluence by S.V. Bykova, V.V. Zharikov

“…The significant heterogeneity of the fauna of the watershed reservoirs is confirmed by the relatively low similarity of the fauna from different water bodies with the strong difference in the composition of dominant species and the slight difference in the composition of background species, as well as by the fact that ?…”
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Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation by Misty Ruppert, John Pyun, K. V. Chalam, David Sierpina

“…Photoreceptor layer thickness (measured with OCT) strongly correlated with ERG and can be used as a secondary surrogate for monitoring the disease progress.…”
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FACTORS INFLUENCING THE ADOPTION OF INTEGRATED SOIL FERTILITY MANAGEMENT TECHNOLOGIES BY SMALLHOLDER FARMERS IN NAMTUMBO DISTRICT, TANZANIA by Hija Walad Mwatawala, Estherbella Martin Burian

“…Furthermore, there should be a strong emphasis on intercropping maize and legumes as well as rotating legumes with maize.…”
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Positive association of triglyceride glucose index and gestational diabetes mellitus: a retrospective cohort study by Jie Zhang, Xia Fang, Zhan Song, Xue-ke Guo, Dong-mei Lin, Fei-na Jiang, Lin Lin, Zhu-hua Cai

“…In the GDM group, the TyG index was negatively correlated with 25 (OH) D and TBIL, and positively correlated with FBG, TG, and TC.ConclusionsThe TyG index is strongly linked to the development of GDM and is an independent risk factor for predicting it. …”
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Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…Antibacterial assays revealed strong activity against <i>E. coli</i> and <i>S. aureus</i>. …”
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A revisit of the semi-geostrophic eddy east of the Sri Lanka dome with anisotropy insight by Zhou Le, M. V. Subrahmanyam, Pemmani Venkata Subba Raju, Gayan Pathirana, Dongxiao Wang, Dongxiao Wang, Wei Song

“…Further instability analyses indicate that the anisotropic component of BTI is significantly larger than the isotropic component, which is attributed to the weak nonlinear planetary geostrophic convergence of the SG eddy and the strong horizontal shear in mean flow field induced by CE-like SLA. …”
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Waste Coir Nanofiller Fused Gallus-Gallus Fibres Reinforced PMC by V. Vijayan, T. Sathish, R. Saravanan, Kuldeep Kumar, Ganesh K. Jadhav, V. Sharun, R. Elangovan, K. Chellamuthu, Mandeep Singh, Aklilu Teklemariam

“…The interesting results are the preferred resin, supported for good surface finish, interface bonding, and totally in the enhancement of Composite properties. The composites are strong in tension (760.89 MPa) and sufficiently flexible (flexural modulus 5441.32 MPa), absorbed less moisture (5.8 g), high wear-resistant (least weight loss upon abrasion with a value of 0.1989 g), secured good results in dynamic analysis, and ensured homogeneous distribution of fibres in the matrix through a scanning electron microscopy image. …”
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Evaluation of the significance of tumor stromal patterns and peri-tumoral inflammation in head and neck squamous cell carcinoma with special reference to the Yamamoto–Kohama classi... by Geet Bhuyan, Prabir Hazarika, Anju M. Rabha

“…Cancer-associated fibroblasts (CAFs) are the predominant cell type in tumor stroma and are important promoters of tumor progression. …”
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Crotalaria madurensis flavonol glycosides’ antibacterial activity against Staphylococcus aureus by Hala Sh. Mohammed, Salwa A. Abu El Wafa, Mona H. Ibrahim, Rasha Mohammad Fathy, Noha A. Seif-Eldein

“…Molecular docking studies suggested that metabolite 1 exhibited the highest antioxidant and anti-MRSA activity, with strong binding scores like the ligand, indicating an effective interaction and high affinity between metabolite 1 and the target molecule.…”
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