From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes by Ana Luisa Reis, Anusyah Rathakrishnan, Vlad Petrovan, Muneeb Islam, Lynnette Goatley, Katy Moffat, Mai Tuyet Vuong, Yuan Lui, Simon J. Davis, Shinji Ikemizu, Linda K. Dixon

“…We identified the amino acids in the viral protein that mediate the interaction with erythrocytes and used this information to construct a mutant virus that is no longer able to bind these cells. This virus induces strong immune responses that provide high levels of protection against infection with the deadly parental virus.…”
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Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma by Nayia Petousi, Nick P Talbot, Ian Pavord, Peter A Robbins, Nicholas M J Smith, Graham Richmond, Asma Alamoudi, Lorenzo Petralia, Haopeng Xu, Dominic Sandhu, Grant AD Ritchie

“…Responders, unlike Non-Responders, experienced significant improvements in symptoms and FEV1 % predicted (Δ pre-BD FEV115±15% pred, p<0.001) and included a higher proportion of patients in clinical remission at 1 year.Conclusion σlnCl is strongly associated with systemic eosinophilic inflammation in severe type-2 high asthma. …”
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Activation of Delta-Opioid Receptor Protects ARPE19 Cells against Oxygen-Glucose Deprivation/Reoxygenation-Induced Necroptosis and Apoptosis by Inhibiting the Release of TNF-α by Runjie Guo, Ping Chen, Tiantian Fu, Ren Zhang, Yuan Zhu, Nange Jin, Hong Xu, Yong Xia, Xuesong Tian

“…Conclusion. These results strongly suggest that DOR activation inhibits necroptosis and apoptosis by decreasing TNF-α release, leading to the prevention of OGD/R-induced injury in ARPE19 cells. …”
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Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…While some participants reported feelings of uncertainty when they started using 5FU, at the end of the study, all 12 participants strongly agreed that the cream was safe and were confident they used it correctly. …”
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A rare intersection: squamous cell carcinoma of the tonsil and the anti-TIF1 syndrome masquerade by Manush Sondhi, Megan Lear, Saleha Dar, Madiha Tariq

“…Conclusions TIF1 dermatomyositis is a unique subset of dermatomyositis with a strong association with malignancy, particularly squamous cell carcinoma (SCC). …”
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Cross-Platform Ecological Momentary Assessment App (JTrack-EMA+): Development and Usability Study by Mehran Sahandi Far, Jona M Fischer, Svea Senge, Robin Rathmakers, Thomas Meissner, Dominik Schneble, Mamaka Narava, Simon B Eickhoff, Juergen Dukart

“…It also has configurable assessment logic and the ability to include supplementary materials for a richer user experience. It strongly commits to security and privacy and complies with the General Data Protection Regulations to safeguard user data and ensure confidentiality. …”
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Evaluating the Relationship between Factors Enhancing the Competitiveness of Customer Foreign Currency Services in the Banking Industry by Saeideh Rahimi, Alireza Rousta, Farzad Asayesh

“…Emphasis on exclusivity and strong competitive power within the banking network can significantly impact the performance and portfolios of banks. …”
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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Results Using machine learning algorithms, five biomarkers (TSPO, HIGD1A, NDUFAB1, NT5DC3, and MRPS30) were successfully identified, and a nomogram model with strong diagnostic ability and accuracy (AUC > 0.9) was constructed. …”
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Seasonal Trends, Profiles, and Exposure Risk of PM2.5-bound Bisphenol Analogs in Ambient Outdoor Air: A Study in Shanghai, China by Janvier Munyaneza, Fahim A. Qaraah, Qilong Jia, Hanting Cheng, Huajun Zhen, Guangli Xiu

“…The highest average concentrations (BPA: 3.47 ng m−3; BPF: 2.46 ng m−3; BPS: 0.58 ng m−3, and bisphenol AF (BPAF): 1.14 ng m−3) were found within samples collected in winter periods. A strong and positive correlation was denoted between the concentrations of BPA and bisphenol B (BPB) (r = 0.719, p < 0.05), when an inversely significant correlation was noticed between BPA and BPF (r = –0.264, p < 0.05). …”
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Insights into a Renowned Fishery: Distinct Spatial Patterns, Environmental Predictors and Species Associations of Trophy-Class Spotted Seatrout (<i>Cynoscion nebulosus</i> [Cuvier... by Catherine Eckert, Elliot Briell, Ethan Getz

“…Salinity and bay were strong predictors for the abundance of both size classes, with peak abundances of both trophy-class and adult-class trout in Baffin Bay and its tertiary bays and at salinities of 10–30 and above 60 psu. …”
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Optimasi Pertanian Padi: Peramalan Curah Hujan Berbasis Arima Untuk Penentuan Waktu Tanam Yang Tepat by Sofi Defiyanti, Betha Nurina Sari, Tesa Nur Padilah

“…Abstract Growth and production of rice cannot be separated from the strong influence of climate change. Recent years of high climate anomalies have posed a threat to agricultural production, particularly rice cultivation. …”
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Exploring the upper ocean characteristics of a bay using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran

“…During the simulation, there is a high correlation (0.96) between the evolution of the salinity and temperature values obtained from the model and the corresponding data from the World Ocean Atlas. This indicates a strong agreement between the model-based simulations and the assimilated data, as supported by the notable correlation values of 0.96 for salinity and temperature. …”
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Cuproptosis-Related Signature Predicts the Prognosis, Tumor Microenvironment, and Drug Sensitivity of Hepatocellular Carcinoma by Xiangjun Qi, Jiayun Guo, Guoming Chen, Caishan Fang, Leihao Hu, Jing Li, Chi Zhang

“…Copper (Cu) metabolism is strongly associated with liver disease. Cuproptosis is a novel format of cell death, and cuproptosis-related genes (CRGs) were identified. …”
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A Localized Model for Branding in the Iranian Dairy Industry by Shaghayegh Sabaghi, Alireza Rousta, Farzad Asayesh

“…ObjectiveBranding is the process of creating a strong awareness of a product or service in the market using a logo, design, symbol, or slogan i.e. the elements used in advertising. …”
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Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children by Ana Torres-Costoso, Vicente Martínez-Vizcaíno, Andreia Oliveira, Mairena Sánchez-López, Eva Rodríguez-Gutiérrez, Sergio Núñez de Arenas-Arroyo, Montserrat Solera-Martínez, Blanca Notario-Pacheco, Vanessa Martínez-Madrid, Arthur Eumann Mesas

“…Results Children in the high-RC subgroups, specifically those with low LDL-c/high RC and high LDL-c/high RC, presented significantly greater insulin levels and WC than did their peers in the low-RC subgroups. RC was more strongly associated with cardiometabolic risk factors than LDL-c (insulin β = 2.073/ − 0.026; HOMA-IR β = 0.451/ − 0.002; MAP β = 1.214/0.300; WC β = 2.842/1.058; and CRF β = − 0.316/ − 0.194 for RC and LDL-c, respectively). …”
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SPECIFIC FEATURES IN THE EXPRESSION OF INTRASPECIES VARIABILITY OF PRUNUS PUMILA FRUITS IN CHELYABINSK PROVINCE IN THE PROCESS OF INTRODUCTION by M. S. Lezin, V. S. Simagin, A. V. Lokteva

“…The ventral suture was usually barely noticeable, less frequently moderately (3.1%) or strongly expressed (1.0%). Polymorphism was observed in the pulp color, which was usually green-pink (72.8%). …”
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INFORMACIJOS VISUOMENĖS STUDIJŲ PASTOLIAI: NAUJŲJŲ VYNMAIŠIŲ BEIEŠKANT by Marius P. P. Šaulauskas

“…The article argues that even a permanent failure to prove this existential presupposition in whatever weak or strong version cannot deprive the information society studies of the legitimacy. …”
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Deciphering the role of flutamide, fluorouracil, and furomollugin based ionic liquids in potent anticancer agents: Quantum chemical, medicinal, molecular docking and MD simulation... by Danish Ali, Muhammad Arif Ali, Muhammad Sarfraz, Afifa Yousuf, Rasham Zulfiqar, Abdul Rauf, Hong-Liang Xu, Muhammad Arshad

“…Notably, the IL pair [FT1]+[NH]– possessed substantial interaction energies in the gas phase (−426.64 kcal/mol), in benzene (−390.24 kcal/mol), and in water (−369.69 kcal/mol), highlighting its potential to disrupt cancer cell growth and exhibit strong anticancer efficacy. The stability of [FT1]+[NH]– was further corroborated by significant Gibbs free energy and enthalpy values (−545.30 and −560.36 kcal/mol). …”
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Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators by Michael Hecker, Brit Fitzner, Isis Ludwig-Portugall, Friederike Bohne, Edmar Heyland, Juliane Klehmet, Matthias Grothe, Matthias Schwab, Alexander Winkelmann, Stefanie Meister, Ales Dudesek, Hannah Wurm, Ilya Ayzenberg, Ingo Kleiter, Ingo Kleiter, Corinna Trebst, Martin W. Hümmert, Bernhard Neumann, Bernhard Neumann, Klaus Eulitz, Dirk Koczan, Uwe K. Zettl

“…In contrast, MS patients who underwent apheresis (nmax=27) showed strong immunoglobulin reduction rates, especially for IgG, and decreased antibody reactivities against all tested peptides. …”
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Statistical Downscaling Method for Vegetation Optical Depth Based on NDVI by Wang Xinyu, Fang Shibo, Han Jiahao

“…As an optical vegetation index, NDVI is proven to have a strong correlation with VOD. The spatial resolution of NDVI is typically high, with numerous kilometer-scale products being widely used. …”
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