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  1. 17601

    Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts by Wisdom U. Ike, Okereke C. Stanley, Nosiri Ijeoma, Okamgba C. Okezie, Nwokocha W. Osita, Aguwanba Chinedu, Aaron C. Friday

    Published 2024-12-01
    “…More so, stable complexes were formed between Class A beta-lactamase enzyme (PDB: 3BLM), Butylated hydroxytoluene (CID: 31404) and 5-Eicosene (CID: 5364600), at different positions, indicating strong and favorable interactions. However, it is essential to note that these results are based on computational predictions, emphasizing the importance of experimental validation to confirm the actual nature and strength of the interaction. …”
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  2. 17602

    Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer by Xiao He, Xianjie Cheng, Zhun Zhang, Lanhui Chen, Changjun Xie, Mengjie Tang

    Published 2025-01-01
    “…Furthermore, overexpression of IL33 significantly inhibited BRCA growth and motility in vitro and in vivo, while also enhancing their vulnerability to destruction by activated CD8+ T cells.ConclusionThe ERG-based risk model effectively predicts the prognosis of BRCA patients and shows a strong link with the immune microenvironment. IL33 stands out as a significant prognostic marker, crucial in the onset and advancement of BRCA. …”
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  3. 17603

    The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression by Callan L. Attwell, Inés Maldonado-Lasunción, Ruben Eggers, Bastiaan A. Bijleveld, Ward M. Ellenbroek, Natascha Siersema, Lotte Razenberg, Dédé Lamme, Nitish D. Fagoe, Ronald E. van Kesteren, August B. Smit, Joost Verhaagen, Matthew R. J. Mason

    Published 2025-02-01
    “…Abstract Background Axon regeneration after injury to the central nervous system (CNS) is limited by an inhibitory environment but also because injured neurons fail to initiate expression of regeneration associated genes (RAGs). The potential of strong RAG expression to promote regeneration in the CNS is exemplified by the conditioning lesion model, whereby peripheral nerve injury promotes regeneration of centrally projecting branches of the injured neurons. …”
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  4. 17604

    Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn’s Disease Activity and Severity Assessment by Deng Y, Fu T, Gao D, Zhou J, Nie X, Wang F, Yu Q

    Published 2025-01-01
    “…The CD activity and severity prediction nomograms showed high C-indices (0.8038 and 0.8208), indicating strong predictive performance.Conclusion: SII is a valuable biomarker for assessing CD severity and monitoring mucosal healing post-treatment. …”
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  5. 17605

    Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation by S.H. Larekeng, M. Nursaputra, M.F. Mappiasse, S. Ishak, M. Basyuni, E. Sumarga, V.B. Arifanti, A.A. Aznawi, Y.I. Rahmila, M. Yulianti, R. Rahmania, A. Mubaraq, S.G. Salmo III, H. Ali, I. Yenny

    Published 2024-07-01
    “…This study demonstrated a strong correlation between the normalized difference vegetation index extracted using unmanned aerial vehicle and mangrove carbon levels obtained from actual field measurements.…”
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  6. 17606

    Evaluating the use of coronary artery calcium scoring as a tool for coronary artery disease (CAD) risk stratification and its association with coronary stenosis and CAD risk factor... by Afrose Liaquat, Ameerdad Khan, Saeed Ullah Shah, Hania Iqbal, Safa Iqbal, Atif Iqbal Rana, Habib Ur Rahman

    Published 2022-07-01
    “…Moreover, plaques with higher calcium burden were found in the left anterior descending artery (mean CACS: 386.15±203.89), followed by right coronary (239.77±219.83) and left circumflex (175.56±153.54) arteries.Conclusion The results indicate a strong positive association of CACS with coronary artery stenosis. …”
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  7. 17607

    Physiological impact of Trichoderma viride agents on the quality and production of melon that is grown on soils continuously cropped to melon by Jingyi Liu, Hua Lian, Jingwei Dou, Jingjing Li, Guangliang Zhu, Jiatong Wang, Guangshu Ma, Mei Li

    Published 2025-02-01
    “…The treatment of 6.4 × 105 CFU/g had the best promoting effect on the morphology of melon seedlings, and the plant height, stem diameter, leaf area, fresh weight of whole plant, dry weight of whole plant, root shoot ratio, and strong seedling index of melon seedlings increased by 90.39, 46.30, 37.55, 81.35, 100.62, 51.47, and 240.00%, respectively, compared with CK. …”
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  8. 17608

    Tea cultivation: facilitating soil organic carbon accumulation and altering soil bacterial community—Leishan County, Guizhou Province, Southwest China by Yingge Shu, Shan Xie, Hong Fan, Chun Duan, Yuansheng Liu, Zuyong Chen

    Published 2025-01-01
    “…In conclusion, tea plantation soil exhibited the highest organic carbon content at 40 years of tea planting, indicating strong carbon accumulation capacity. However, soil acidification in the tea plantation may affect changes in organic carbon and bacterial community. …”
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  9. 17609

    A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity by Wen Wang, Wen Wang, Meiting Wang, Huanbai Wang, Weifeng Xu, Conggang Wang, Jie Pei, Xiaodan Li, Dongting Zhangsun, Dongting Zhangsun

    Published 2025-01-01
    “…Specifically, α-Conotoxins [D1G, ΔQ14] LvIC, identified from Conus lividus, have demonstrated strong activity on α6β4* nAChRs in vitro. However, the effects of [D1G, ΔQ14] LvIC have not been investigated in vivo. …”
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  10. 17610

    Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021Research in context by Yuzhe Pan, Qian Liu, Nan Zhang, Shuang Peng, Xinqi Li, Fuling Zhou

    Published 2025-01-01
    “…Our findings reveal a strong association between leukemia QCI and regional economic and educational development. …”
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  11. 17611

    Unraveling the transcriptomic effects of leucine supplementation on muscle growth and performance in basketball athletes. by Sinan Wang, Weishuai Guo, Rui Dong

    Published 2025-01-01
    “…Weighted Gene Co-expression Network Analysis (WGCNA) identified a module (turquoise) strongly associated with muscle growth, with DEGs in this module enriched in cytoskeletal pathways in muscle cells. …”
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  12. 17612

    Inter-session Reliability of Magnetic Nerve Stimulation and Within-Session comparison to Electrical Nerve Stimulation in Evaluating Neuromuscular Function of Knee Extensor Muscles by Romina Ledergerber, Martin Keller

    Published 2025-01-01
    “…Intraclass correlation (ICC), Coefficient of variation (CV) and mean absolute percentage error (MAPE) were used to assess measurement precision. Results There was strong agreement between MNS and ENS for RS, RD and VA (ICC=0.77-0.88). …”
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  13. 17613

    Phylogenomic analysis reveals exceptions to the co-evolution of ZAR1 and ZRK immune gene families in plants by Li Yang, Shengyi Liu, M. Eric Schranz, Klaas Bouwmeester

    Published 2025-01-01
    “…Here we now report other exceptions on the concerted ZAR1-A–ZRKs presence-absence pattern within several early diverging monocot lineages, including the genome of Acorus tatarinowii—a species representing the first branching monocot lineage. We also revealed strong variation in ZAR1-A–ZRKs co-occurrence within the asterid order Ericales, suggesting patterns of de-coevolution in angiosperms. …”
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  14. 17614

    Association of IL-8 and CXCR2 with AST/ALT Ratio in Liver Abnormalities Screening during Oxidative Stress Injury Caused by VCM by Yiwen Dong, Xingang Wang, Weijiang Hu, Xin Wang, Hongying Bian, Wencui Zhang, null Feng Han, Ning Kang, Lin Zhang, Meng Ye

    Published 2024-01-01
    “…ALT, AST, and AST/ALT ratio all contributed to liver abnormalities that contained fatty liver, liver calcification, and liver cysts, IL-8 and CXCR2 correlated with each other strongly and showed significant associations with oxidative stress markers, even AST/ALT ratio. …”
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  15. 17615

    Three-way relationships between gut microbiota, helminth assemblages and bacterial infections in wild rodent populations by Bouilloud, Marie, Galan, Maxime, Dubois, Adelaide, Diagne, Christophe, Marianneau, Philippe, Roche, Benjamin, Charbonnel, Nathalie

    Published 2023-02-01
    “…They remain difficult to generalize due to the strong impact of the environment on these interactions, even at regional geographical scales. …”
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  16. 17616

    Degassing at the Volcanic/Geothermal System of Kos (Greece): Geochemical Characterization of the Released Gases and CO2 Output Estimation by Kyriaki Daskalopoulou, Antonina Lisa Gagliano, Sergio Calabrese, Lorenza Li Vigni, Manfredi Longo, Konstantinos Kyriakopoulos, Giovannella Pecoraino, Walter D’Alessandro

    Published 2019-01-01
    “…Isotope composition of He ranges from 0.85 to 6.71 R/RA, indicating a sometimes-strong mantle contribution; the highest values measured are found in the two highly degassing areas of Paradise beach and Volcania. …”
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  17. 17617

    Gambaran Kejadian Persalinan Disfungsional pada Pasien Anemia dalam Kehamilan di RSUP Dr. M. Djamil Periode 2010–2012 by Mega Redha Putri, Joserizal Serudji, Efrida .

    Published 2015-05-01
    “…The strength of uterine contractions or his in pregnant women with anemia is less than normal, weak and short in duration so it is not strong enough to bear the fetus and the pregnant women will get tired, causing a slow or stopped. …”
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  18. 17618

    Using OCO-2 Observations to Constrain Regional CO<sub>2</sub> Fluxes Estimated with the Vegetation, Photosynthesis and Respiration Model by Igor B. Konovalov, Nikolai A. Golovushkin, Evgeny A. Mareev

    Published 2025-01-01
    “…Furthermore, the posterior NEE estimate is found to be robust to strong biases and random uncertainties in the CHIMERE boundary conditions. …”
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  19. 17619

    A Realistic Approach to Calculating the Nitrogen Use Efficiency Index in Cereals with Winter Wheat (<i>Triticum aestivum</i> L.) as an Example by Witold Grzebisz, Jarosław Potarzycki

    Published 2025-01-01
    “…The apparently low NUE index in this phase clearly indicates (i) the high potential of winter wheat for grain set per ear, (ii) consequently resulting in a strong depletion of N soil resources during the GFP. …”
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  20. 17620

    Wind–Wave Misalignment in Irish Waters and Its Impact on Floating Offshore Wind Turbines by Thomas Shanahan, Breiffni Fitzgerald

    Published 2025-01-01
    “…Using the ERA5 reanalysis dataset validated against Irish Marine Data Buoy Observation Network measurements, the results showed a satisfactory accuracy with an average wind speed error of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>−</mo><mn>0.54</mn></mrow></semantics></math></inline-formula> m/s and a strong correlation coefficient of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>0.92</mn></mrow></semantics></math></inline-formula>. …”
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