Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a p... by Ziyu Weng, Chenzhong Wang, Bo Liu, Yi Yang, Yueqi Zhang, Chi Zhang

“…Molecular docking analysis using AutoDock Vina revealed that progesterone exhibited binding energies of ≤ -7 kcal/mol with each of the key proteins, indicating strong binding affinity. Furthermore, molecular dynamics simulations validated the stability and strength of these interactions. …”
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Reliability of an Observational Biomechanical Analysis Tool in Adolescent Baseball Pitchers by Steven F DeFroda, Dai Sugimoto, Steven J Staffa, Donald S Bae, Ellen Shanley, Charles A Thigpen, Peter K Kriz

“…The ACES tool demonstrated acceptable kappas for individual items and strong ICC 0.91 (95% CI: 0.82, 0.96) for total scores across the trials. …”
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Clinicians’ user experience with health information exchange technologies during simulated medication reconciliation by Himalaya Patel, April Savoy, Steven L. Sanchez, Morgan Traylor, Khoa A. Nguyen, Kenneth S. Boockvar, Vincent S. Fan, Emily R. Locke, Bryan Gibson, Amanda S. Mixon, Susan H. Byerly, David A. Haggstrom, Teresa M. Damush, Michael Weiner, Alissa L. Russ-Jara

“…After tasks, participants used the UMUX-Lite instrument to rate each technology's ease of use and utility (each range 1–7; 7=strongly agree). To identify design-related barriers, we coded and interpreted usability and content problems that participants encountered. …”
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Validation study of synthetic models for esophageal atresia with tracheoesophageal fistula (EA/TEF): A simulation-based training in pediatric surgery by Zahradníková Petra, Hnilicová Silvia, Lindák Martin, Pechanová Rebeka, Števková Dominika, Vitovič Pavol, Laurovičová Miroslava, Horn František, Tvrdoň Tomáš, Babala Jozef

“…Additionally, 15 individuals (45.5 %) strongly agree and 48.5 % agree that regular training on simulators enhances surgical skills in MIS procedures in the operating room. …”
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Vapor pressure deficit (VPD) downscaling based on multi-source remote sensing, in-situ observation, and machine learning in China by Mi Wang, Zhuowei Hu, Xiangping Liu, Wenxing Hou

“…The high accuracy demonstrated in year-to-year and station-to-station experiments, coupled with the strong consistency between RF-VPD data and in-situ observations, underscores the robustness and applicability of RF-VPD models in capturing spatiotemporal patterns. …”
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Limited Diagnostic Value of miRNAs in Early Trauma-Induced Liver Injury: Only miRNA-122 Emerges as a Late-Phase Marker by Jason-Alexander Hörauf, Amit Singh, Maika Voth, Hamed Moheimani, Cora Rebecca Schindler, Borna Relja, Liudmila Leppik, Ingo Marzi, Dirk Henrich

“…There was a moderate correlation between miRNA-122-5p and AIS_Abdomen (<i>p</i> = 0.056) and transfused red blood cell concentrates (<i>p</i> = 0.055). L-FABP correlated strongly with the ALT levels (<i>p</i> = 0.0009) and the length of stay in the ICU (<i>p</i> = 0.0086). …”
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Prevalence and Associated Factors of Overweight and Obesity among Primary School Children Aged 7–17 Years in Urban Mbarara, Uganda by Benedict Twinomugisha, Abdon Marius Birungi

“…Modes of transport were only found to be strongly associated with overweight/obesity. There is a need to establish evidence-based strategies to inform policy on prevention of childhood overweight/obesity.…”
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Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis by Lisanne B. M. Bakker, Claudine J. C. Lamoth, Tomas Vetrovsky, Markus Gruber, Simone R. Caljouw, Ward Nieboer, Wolfgang Taube, Jaap H. van Dieën, Urs Granacher, Tibor Hortobágyi

“…The behavioral and neural mechanisms of strong task-specificity and the time course of skill retention remain unclear and require further studies in young and older individuals. …”
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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

“… # RESULTS One way analysis of variance (ANOVA) showed statistically significant differences in Type I and Type IV Kibler scapula classification for the CKCUEST power score, however when an ANCOVA controlled for body mass index, there was no statistically significant difference. A strong correlation r=.94 was observed between student and experienced physical therapist in evaluating all four types of Kibler scapular classification…”
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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…This study demonstrates a low prevalence of SP in Wales when compared to global estimates and strong associations to a variety of determinants. …”
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LDWLE: self-supervised driven low-light object detection framework by Xiaoyang shen, Haibin Li, Yaqian Li, Wenming Zhang

“…In qualitative measurements, LDWLE can accurately detect most objects on both public real-world low-light datasets and self-collected ones, demonstrating strong adaptability to varying lighting conditions and multi-scale objects.…”
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A qualitative study of stigma in patients with low anterior resection syndrome of rectal cancer (直肠癌低位前切除综合征患者病耻感的质性研究) by WEN Ruizhen (温瑞珍), CHEN Piao (陈飘), LI Yalan (李亚兰), CAO Aifang (曹爱芳), WANG Miaolan (王淼兰), ZHENG XiaoXuan (郑筱暄), PENG Hui (彭慧)

“…Conclusion Patients with LARS of rectal cancer have strong stigma. Medical staff should pay full attention to the stigma of patients and provide them with relevant nursing intervention and psychological support. …”
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Assessment of Antibiotic Resistance Among Isolates of <i>Klebsiella</i> spp. and <i>Raoultella</i> spp. in Wildlife and Their Environment from Portugal: A Positive Epidemiologic Ou... by Carolina Sabença, Rani de la Rivière, Paulo Barros, João Alexandre Cabral, Roberto Sargo, Luís Sousa, Maria de Lurdes Enes Dapkevicius, Filipe Silva, Filipa Lopes, Ana Carolina Abrantes, Madalena Vieira-Pinto, Manuela Caniça, Gilberto Igrejas, Carmen Torres, Patrícia Poeta

“…Most of the <i>Klebsiella</i> spp. and <i>Raoultella</i> spp. isolates were biofilm producers (except for one <i>Klebsiella</i> isolate), and 45.6% were weak biofilm producers, with the remaining being moderate to strong biofilm producers. We can conclude that antibiotic resistance is not widespread in these environment-associated isolates, which is a positive epidemiological outcome. …”
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Relationships between structural stigma, societal stigma, and minority stress among gender minority people by Kristen D. Clark, Mitchell R. Lunn, Jae M. Sevelius, Carol Dawson-Rose, Sandra J. Weiss, Torsten B. Neilands, Micah E. Lubensky, Juno Obedin-Maliver, Annesa Flentje

“…We examined potential variables representing structural stigma, including variables that are inclusive of societal stigma, to identify those that most strongly relate to minority stress outcomes. We tested variables identified in the literature as measures of structural stigma inclusive of societal stigma (LGBT + Business Climate Index, state voting behaviors, and Google Trends search data), the most commonly used structural stigma variable (State Policy Environment Tally), and proxy variables (region, population density) for comparison. …”
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Resilience of Fishery Economy in Fujian Coastal Areas from the Perspective of Institutional Evolution by Leng Yun, Wei Suqiong, You Xiaojun, Ren Zhihuang

“…Three main conclusions are drawn: 1) Under the influence of different types of shocks (the super-typhoon in 2006, the financial crisis in 2008, and the upgrading of the fishing industry in 2017), the output value fluctuates significantly owing to the dual effects of production and supply, and the output is more strongly affected by production and more drastically reflective of natural disasters. 2) A spatial regularity exists in the impact of regional crises (typhoons) on industrial resilience resistance; the closer to the disaster center, the poorer the performance of industrial resilience resistance. …”
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Examining the Leverage Effect, Dynamic Conditional Correlation, and Volatility Spillover Among Selected Indices of the Tehran Stock Exchange: Evidence from the ARMA-DCC-GJR-GARCH M... by Gholamhosein Golarzi, Seyed Ramin Abolfazli

“…Also, the result of DCC (1,1) indicates the conditional correlation between all variables is positive and volatility spillover among them was strongly confirmed. ConclusionFinancial markets, particularly the stock market, exhibit varied responses to positive and negative shocks, and these shocks impact the correlation between variables. …”
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Developing a Model for Successful Implementation of Customer Experience Management in Organizations: A Qualitative Study by Payam Mardazad Navi, Kambiz Heidarzadeh Hanzaee, Seyyed Buik Mohammadi, Mohsen Khoon Siavash

“…Objective Building a strong customer experience is currently one of the most important management goals. …”
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Innowacje na rynku produktów żywnościowych z perspektywy polskich i czeskich konsumentów generacji Y by Anetta Barska

“…Obecnie na rynku zarysowują się dwie przeciwstawne tendencje z jednej strony nasilająca się globalizacja przyczynia się do ujednolicania postaw i zachowań konsumentów, a z drugiej - nasila się rola tożsamości, co skłania do regionalizacji. …”
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Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. by Eiman Abdo, Mohammad A Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A Ababneh

“…In pancreatic cancer, the tumor microenvironment is notably hypoxic and exhibits strong immunosuppressive properties. Given that immunotherapy is now approved for pancreatic cancer treatment, further understanding of how pancreatic tumor cell hypoxia influences T-cell cytotoxicityis essential.…”
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Using the HBSC Symptom Checklist to measure junior secondary school students’ psychosomatic complaints in the Chinese Mainland: Rasch-based validation, population-based norm, and n... by Yuhang Zhu, Xianzhu Cong, Zhenliang Qiu, Ricky Jeffrey, Ranran Li, Li Jing, Gaopei Zhu, Xi Yang, Shuang Li, Jinling Wang, Xu Xu, Hongliu Zhu, Xinjian Wang, Ling Huang, Xueqin Sun, Di Wu, Kai Zhang, Xunhong Miao, Rui Wen, Qinglang Huang, Zhuang He, Juan Li, Alina Cosma, Fuyan Shi, Suzhen Wang, the PROSQoL-JSSS research group

“…All 5-category rating scales of eight items appropriately differentiated the students’ PSC and demonstrated strong goodness-of-fit. This version also exhibited good unidimensionality and local independence. …”
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