Development and validation of a prognostic model for critically ill type 2 diabetes patients in ICU based on composite inflammatory indicators by Lin Liu, Yan-Bo Zhao, Zhuo-Ting Cheng, Ya-Hui Li, Yang Liu

“…Calibration curves demonstrated strong consistency in both sets. In addition, decision curve analysis showed a net clinical benefit within 1–60% threshold probability in the test set and 10–41% threshold probability in the external validation set. …”
Get full text

A deep learning approach for classifying and predicting children's nutritional status in Ethiopia using LSTM-FC neural networks by Getnet Bogale Begashaw, Temesgen Zewotir, Haile Mekonnen Fenta

“…The LSTM-FC model demonstrates strong generalization performance across multiple folds, with high recall and consistent F1-scores, indicating its robustness in predicting nutritional status. …”
Get full text

Ten pressure points in primary care during COVID-19: findings from an international narrative review by Sally Hall Dykgraaf, Anne Parkinson, Michael Wright, William C. W. Wong, Jane Desborough, Lauren Ball, Elizabeth Sturgiss, Garang M. Dut, Katelyn Barnes, Danielle Butler, Steph Davis, Kirsty Douglas, Candan Kendir, Danielle Martin, Robert Marten, Katherine Rouleau, Shannon Barkley, Lucas de Toca, Michael Kidd

“…Abstract Background Strong primary care (PC) services are the foundation of high-performing health care systems and can support effective responses to public health emergencies. …”
Get full text

Awareness and perception of prevention and management options of sexually transmitted infections among students at secondary school in Rivers State, Nigeria by Florence Mandah, Oluebubechukwu Udi, Pamela Thompsom-Abiye, Basil Ogbu

“…Results 99.3% of participants agreed that STIs can be treated with pharmaceutical drugs, 33% believed in the effectiveness of local concoctions, while 68.3% indicated that divine intervention of prayers offers a cure. 290 (96.6%) participants strongly agreed that young people should be educated on STIs in schools. …”
Get full text

The Superiority of Removable Contact Splints in the Healing of Diabetic Foot during Postoperative Care by Vladimíra Fejfarová, Jaroslav Pavlů, Robert Bém, Veronika Wosková, Michal Dubský, Andrea Němcová, Alexandra Jirkovská, Bedřich Sixta, Karol Sutoris, Filip Thieme, David G. Armstrong, Eliška Vrátná, Jitka Hazdrová, Věra Lánská

“…The lowest number of postoperative complications (number of reamputations: p=0.028; rehospitalizations: p=0.0085; and major amputations: p=0.02) was in group R compared to groups W and WP. There was a strong trend toward a higher percentage of healed patients (78.4% vs. 55.7% and 65.5%; p=0.068) over a shorter duration (13.7 vs. 16.5 and 20.3 weeks; p=0.055) in the R group, as well. …”
Get full text

Influence of drought stress on phosphorus dynamics and maize growth in tropical ecosystems by Mohsin Mahmood, Jujie Wang, Sajid Mehmood, Waqas Ahmed, Anam Ayyoub, Mahmoud F. Seleiman, Ahmed Salah Elrys, Ahmed S. M. Elnahal, Adnan Mustafa, Xiuwen Wei, Weidong Li

“…RDA highlighted a positive link between phosphatase activity and reduced labile P, while P uptake and biomass were strongly associated with labile and moderately labile P fractions. …”
Get full text

Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit by Maitee Rosende-Roca, Fernando García-Gutiérrez, Yahveth Cantero-Fortiz, Montserrat Alegret, Vanesa Pytel, Pilar Cañabate, Antonio González-Pérez, Itziar de Rojas, Liliana Vargas, Juan Pablo Tartari, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Mariola Moreno, Sílvia Preckler, Susanna Seguer, Miren Jone Gurruchaga, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Mercè Boada, Marta Marquié

“…Conclusions Our findings do not strongly support the notion that sex significantly modifies the clinical progression of AD dementia based on cognitive data. …”
Get full text

Rhopalurus junceus scorpion venom induces G2/M cell cycle arrest and apoptotic cell death in human non-small lung cancer cell lines by Alexis Díaz-García, Ángel Garrido, Jenny Laura Ruiz-Fuentes, Tamara Hermosilla, Diego Varela

“…Additionally, combined etoposide/venom exposure provoked G2/M arrest and apoptosis in NSCLC more strongly than either substance alone. Furthermore, upon crude venom fractioning through RP-HPLC, we found two soluble fractions with high cytotoxic effects. …”
Get full text

Visualization of Small Vessels by Micro–Computed Tomography Using Titanium Dioxide Nanoparticles as a Novel Contrast Agent by Taku Goto, Ruriko Tanabe, Hirotoshi Shibuya, Masaru Tamura, Shintaro Nomura

“…Consequently, using titanium dioxide as a contrast agent allows us to achieve a higher contrast-to-noise ratio while maintaining a favorable signal-to-noise ratio. Our results strongly support the notion that TiO2-NPs as a contrast agents hold promise not only for investigating circulatory disorders in experimental pathology but also for uncovering new insights in anatomical physiology.…”
Get full text

Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification of <i>Mycobacterium bovis</i>-Infected Domestic Dogs (<i>Canis lupus familiaris</i>) by Conor O’Halloran, Paul Burr, Danielle A. Gunn-Moore, Jayne C. Hope

“…The production of antigen-specific tumour necrosis factor-alpha (TNF-α) by PBMC in response to a cocktail of ESAT-6 and CFP-10 peptides correlated very strongly with the overall IGRA results, suggesting future diagnostic potential. …”
Get full text

A graph neural network approach for hierarchical mapping of breast cancer protein communities by Xiao Zhang, Qian Liu

“…These identified protein communities, in conjunction with other protein communities under strong mutation and survival burdens, can potentially be used as clinical biomarkers for breast cancer.…”
Get full text

Mechanisms linking river flow regime and riparian hardwood establishment by Steven F. Railsback, John H. Bair

“…Further, under both reservoir‐controlled and unimpaired flow regimes, establishment was strongly determined by post‐deposition flow increases: seeds deposited at elevations low enough to support rooting were often killed via inundation or scour in flow fluctuations that occurred under both reservoir‐regulated and unregulated flow scenarios. …”
Get full text

The Role of the Military-Political Elite of Egypt in the Struggle for National Independence in the Post-World War II Period (1945-1952) by I. E. Ibragimov

“…An important aspect of this trend is that, in the run-up to the Egyptian Revolution of 1952, the officers and the military elite became a more prepared and organized than other groups and was able to quickly and almost bloodlessly take power into their own hands.The article notes that it is impossible to solve urgent social problems and overcome economic backwardness without centralized strong leadership. While forming the Egyptian statehood and the Kingdom of Egypt, there were three centers of power – Wafd party led by Saad Zaghloul, the king and his supporters, as well as Great Britain, which retained control over Egypt. …”
Get full text

Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans by Muhammad Sadiq Khan, Ayesha Akter, Ismail Khan, Luis Carlos Ramos Aguila, Lina Akter, Mengmeng Yang, Xu Li, Yuelin Li

“…Climatic factors, including annual mean precipitation and air temperature, were strongly correlated with greenness, influencing 76 % and 78 % of the pixels, respectively, with increased rainfall observed in dense mangrove areas. …”
Get full text

Preliminary Data on <i>Silybum marianum</i> Metabolites: Comprehensive Characterization, Antioxidant, Antidiabetic, Antimicrobial Activities, LC-MS/MS Profiling, and Predicted ADME... by Sabrina Lekmine, Ouided Benslama, Mohammad Shamsul Ola, Nabil Touzout, Hamza Moussa, Hichem Tahraoui, Haroun Hafsa, Jie Zhang, Abdeltif Amrane

“…Results: The extract contained 251.2 ± 1.2 mg GAE/g of total phenolics and 125.1 ± 1.6 mg QE/g of total flavonoids, with 33 metabolites identified, including phenolic acids, tannins, flavonoids, and flavolignans. Strong antioxidant activity was observed, with IC₅₀ values of 19.2 ± 2.3 μg/mL (DPPH), 7.2 ± 1.7 μg/mL (ABTS), 22.2 ± 1.2 μg/mL (CUPRAC), 35.2 ± 1.8 μg/mL (Phenanthroline), and 24.1 ± 1.2 μg/mL (FRAP). …”
Get full text

Characteristics of the macroinvertebrate community structure and their habitat suitability conditions in the Chishui River by Xinyu Li, Long Yan, Xu Zhi, Peng Hu, Chongju Shang, Baolong Zhao

“…The optimal conditions for macroinvertebrate communities in the Chishui River were determined to be a DO concentration of 9.8 mg/L and an NH3-N concentration of 0.12 mg/L.DiscussionOverall, the macroinvertebrate community structure in the Chishui River is significantly influenced by factors such as water quality, flow velocity, and substrate particle size, and it demonstrates strong adaptability to seasonal variations.…”
Get full text

The relevance of a multidomain geriatric assessment in older patients with heart failure by Emma E.F. Kleipool, Julia H.I. Wiersinga, Marijke C. Trappenburg, Albert C. vanRossum, Carmen S. vanDam, Su‐San Liem, Mike J.L. Peters, M. Louis Handoko, Majon Muller

“…Conclusions Having limitations in multiple domains appears more strongly associated with short‐term adverse outcomes than HF severity and physical frailty. …”
Get full text

Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes by Chaisiri Kitpaosong, Siriluck Liengprayoon, Erwann Durand, Tucksin Lerksamran, Aurélie Daval, Eric Gohet, Lim Khan Tiva, Phean Chetha, Kong Mengchheang, Phen Phearun, Ung Rattana, Kim Chandy, Pol Sokea, Un Kim Eng, Kittipong Rattanaporn, Bruno Barea, Laurent Vaysse

“…Interestingly, linoleic and palmitoleic acids strongly correlated with the furan fatty acid concentration, indicating a possible biosynthetic pathway linkage. …”
Get full text

Induction of Somatic Embryogenesis and Organogenesis in Zimbabwean Sweet Potato (cv Brondal) by Rose T. Masekesa, Edmore Gasura, Gaudencia T. Kujeke, Elizabeth Ngadze, Farisai Chidzwondo

“…In contrast, plantlets produced under organogenesis were strong, grew vigorously, and could be subcultured several times. …”
Get full text

Combining ability, floral biology, and seed producibility of promising cytoplasmic male-sterile (CMS) lines for hybrid rice development by Victoriano V. Casco, Rosemarie T. Tapic, Jerwin R. Undan, Anna Ma. Lourdes S. Latonio, Roel R. Suralta, Norvie L. Manigbas

“…Also, one important factor that strongly determines the suitability of commercial utilization of hybrid rice parental lines is their extent of seed producibility. …”
Get full text