Differential attainment at national selection for higher surgical training: a retrospective cohort study by Amanda Lee, Jennifer Cleland, John Hines, Peter Brennan, Ricky Ellis, Yasin Al-Tawarah

“…MRCS performance was found to be a strong independent predictor of future success at HST selection. …”
Get full text

Effectiveness of Four-Decontamination Techniques on Bacterial Growth on CPR Manikins after Use in a CPR Course

“…The American Red Cross and American Heart Association are strong advocates of preventing disease transmission during cardiopulmonary resuscitation (CPR) training by promoting careful and consistent manikin decontamination. …”
Get full text

The saprotrophic Pleurotus ostreatus species complex: late Eocene origin in East Asia, multiple dispersal, and complex speciation by Jing Li, Li-Hong Han, Xiao-Bin Liu, Zhi-Wei Zhao, Zhu L. Yang

“…The P. ostreatus species complex was strongly supported as monophyletic, and 20 phylogenetic species were recognized, with seven putatively new species. …”
Get full text

Patient centered medication treatment for opioid use disorder in rural Vermont: a qualitative study by Emily G. Hichborn, Owen B. Murray, Eilis I. Murphy, Tess E. Gallant, Sarah K. Moore, Bethany M. McLeman, John Saroyan, Anthony Folland, Megan Mitchell, Lisa A. Marsch

“…Individualizing care through flexible appointment scheduling was strongly valued, while inflexible scheduling fostered fear of not getting medication. …”
Get full text

Prognostic biomarker soluble ST2 exhibits diurnal variation in chronic heart failure patients by Sandra Crnko, Markella I. Printezi, Tijn P.J. Jansen, Laurynas Leiteris, Manon G. van derMeer, Hilde Schutte, Martijn vanFaassen, Bastiaan C. duPré, Nicolaas deJonge, Folkert W. Asselbergs, Carlo A.J.M. Gaillard, Hans Kemperman, Pieter A. Doevendans, Joost P.G. Sluijter, Linda W. vanLaake

“…Abstract Aim Soluble suppression of tumorigenicity‐2 (sST2) is a strong prognostic biomarker in heart failure. The emerging understanding of circadian biology in cardiovascular disease may lead to novel applications in prognosis and diagnosis and may provide insight into mechanistic aspects of the disease–biomarker interaction. …”
Get full text

Short Pulse Epiretinal Stimulation Allows Focal Activation of Retinal Ganglion Cells by Laurin X. Koppenwallner, Gunther Zeck, Paul Werginz

“…Axonal thresholds were significantly higher for all pulse durations, with the ratio between axonal and somatic thresholds strongly increasing with decreasing pulse duration (1.32 and 4.39 for pulse durations of 500 and <inline-formula> <tex-math notation="LaTeX">$10\mu $ </tex-math></inline-formula>s, respectively). …”
Get full text

The presence of iteroparous salmonid spawning grounds affects the stable isotope signatures of food web components in Swedish boreal streams by Rahmat Naddafi, Magnus Enbom, Carin Magnhagen, Nazila Hajizadeh Koupayh, Daniel Holmqvist, Hans Lundqvist

“…Marine-derived nutrients (MDN) translocated by anadromous fish can strongly be linked to the dynamics and structure of resident freshwater communities. …”
Get full text

Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…Objectives To evaluate whether between hypertension and type 2 diabetes (T2D)—established drivers of chronic kidney disease (CKD) progression—one might be more strongly associated with CKD progression than the other.Design Cohort study using a primary care database (electronic health records).Setting Primary care in Catalonia, Spain.Participants 438 273 patients with CKD identified from the Information System for Research in Primary Care database in Catalonia (2007–2017) and stratified into four mutually exclusive groups based on the presence/absence of hypertension and/or T2D. …”
Get full text

Credit Rating Model of Small Enterprises Based on Optimal Discriminant Ability and Its Empirical Study by Zhanjiang Li, Lin Guo

“…Based on this principle, a nonlinear optimization model for credit rating division of small enterprises is built, and the approximate solution of the model is solved by a recursive algorithm with strong reproducibility and clear structure. The small enterprise credit rating division not only satisfies the principle that the higher the credit grade, the lower the default loss rate, but also satisfies the principle that the credit group of small enterprises matches the credit grade, with credit data of 3111 small enterprises from a commercial bank for empirical analysis. …”
Get full text

Prohexadione-Calcium Reduced Stem and Tiller Damage and Maintained Yield by Improving the Photosynthetic and Antioxidant Capacity of Rice (<i>Oryza sativa</i> L.) Under NaCl Stress by Wanqi Mei, Shaoxia Yang, Jian Xiong, Aaqil Khan, Liming Zhao, Xiaole Du, Jingxin Huo, Hang Zhou, Zhiyuan Sun, Xiaohui Yang, Nana Yue, Naijie Feng, Dianfeng Zheng

“…The current findings strongly suggested that exogenous application of Pro-Ca effectively alleviated the adverse impact of NaCl stress on the main stem and tillers by enhancing the photosynthetic capacity and antioxidant enzyme activity, and ultimately increased the productive tillering rate and grain yield.…”
Get full text

Are We Overlooking Anatomical Contributions to Dynamic Knee Valgus? by Matt Dewald, Madison Andersen, Laura Higgins, Emma Porter, Alex Wickersham

“…When DKV measurements were normalized to an anatomical measurement, no correlations existed with any of the performance measurements. There was very strong inter-rater reliability (ICC=.96-.99) of all the measurements…”
Get full text

Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infect... by Dana Unninayar, Emilia L. Falcone, Hugo Chapdelaine, Donald C. Vinh, Karina A. Top, Beata Derfalvi, Thomas B. Issekutz, Hélène Decaluwe, Anne Pham-Huy, Julia Upton, Stephen D. Betschel, Tamar Rubin, Sneha Suresh, Nicola A. M. Wright, Luis Murguía-Favela, Tatiana Kalashnikova, Lisa Barrett, Sharon Oldford, Marc-Andre Langlois, Corey Arnold, Manish Sadarangani, Tinghua Zhang, Tim Ramsay, Dina Yazji, Juthaporn Cowan, Juthaporn Cowan

“…However, at 6 months after completing the primary series (three doses for IEIs and two doses for healthy), both HI and CMI responses of both IEI participants and healthy controls persisted and were comparable. There was a strong correlation between neutralizing antibody titer (ID50) and anti-spike IgG but not between ID50 and CMI. …”
Get full text

Identification of serum metabolite biomarkers in premature infants with bronchopulmonary dysplasia: protocol for a multicentre prospective observational cohort study by Ping Zhou, Jun Chen, Ying Liu, Cheng Chen, Xin Guo, Zhangbin Yu, Jiebo Liu, Yanping Guo, Dan Dan Rao, Shengnan He, Xudong Yan, Wanxiang He, Songzhou Xu, Ruolin Zhang

“…This study aims to identify the biomarkers that can predict the early occurrence and development of BPD by screening serum metabolites in preterm infants. This will provide strong support for the early prediction of BPD and targeted interventions in future research.Methods and analysis This is a prospective, multicentre, open-label, observational cohort study spanning 3 years. …”
Get full text

Space-time Characteristics of 16 PM2.5-bound Phthalates (PAEs) in Ambient Air from Shanghai: Profiles, Sources, Meteorological Effects, and Exposure Risks by Janvier Munyaneza, Md Faysal Hossain, Qilong Jia, Yusen Duan, Guangli Xiu

“…Two congeners (DBP and DIBP) contributed significantly (79.4%) to the overall concentration of PAEs in the campaign, and exhibited a strong positive correlation (Spearman: r = 0.876, p < 0.05). …”
Get full text

Phenolic Content and Antioxidant and Antimicrobial Activities of Malva sylvestris L., Malva oxyloba Boiss., Malva parviflora L., and Malva aegyptia L. Leaves Extract by Khalid A. Shadid, Ashok K. Shakya, Rajashri R. Naik, Nidal Jaradat, Husni S. Farah, Naeem Shalan, Nooman A. Khalaf, Ghaleb A. Oriquat

“…In addition, the plant extract and acetone extract of M. sylvestris showed a strong antibacterial activity with an MIC value of 0.0078 mg/ml. …”
Get full text

Antimicrobial Efficacy of Five Wound Irrigation Solutions in the Periprosthetic Joint Infection Microenvironment In Vitro and Ex Vivo by Anja L. Honegger, Tiziano A. Schweizer, Yvonne Achermann, Philipp P. Bosshard

“…We measured the bacterial reduction of these irrigation solutions compared to Ringer–Lactate and to the strong bactericidal but not approved Betaseptic solution. …”
Get full text

The relationship between pain, sleep quality, and care dependency in older adults living in a long-term care facility by Grażyna Puto, Anna Kliś-Kalinowska, Agata Musiał

“…Conclusions The study is a valuable addition to research showing a strong link between pain, sleep quality and care dependency. …”
Get full text

Identification and management of a novel Danshen leaf anthracnose caused by Colletotrichum karstii in Salvia miltiorrhiza Bunge in China by Haoyue Ma, Haoyue Ma, Liguo Huang, Lulu Guo, Lulu Guo, Shan Chen, Jiale Liu, Changyun Liu, Yanxia Dou, Xianchao Sun, Lin He, Guanhua Ma

“…Spore germination was most strongly inhibited by the 80 % ethylicin EC, which had an EC50 value of 0.5541 µg/mL. …”
Get full text

Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…Recent evidence suggests that the interleukin −17 (IL17) axis strongly contributes to SpA. This study aimed to assess the efficacy of an IL17A peptide-based vaccine on SpA manifestations in model rats.Methods HLA-B27/human β2-microglobulin (hβ2M) transgenic rats were immunised with heat-inactivated Mycobacterium tuberculosis (MT) to develop spondylitis and arthritis as an experimental SpA model after immunisation with a keyhole limpet hemocyanin-conjugated IL17A peptide-based vaccine with an alum adjuvant three times. …”
Get full text

The effects of mindful self-care on medical resident wellness, depression, and burnout by Wendy M. GUYKER, Evette A. ADDAI, Catherine P. COOK-COTTONE, Susan M. ORRANGE, Sofie SCALETTA

“…Discussion: This research shows that resident self-care is strongly linked to well-being and is associated with lower distress, depression, and burnout. …”
Get full text