Analysis of the mechanism of Zangjiangzhi capsule in the treatment of hyperlipidemia based on its ingredients identified by UHPLC-Q-Exactive-Orbitrap-MS by Changting He, Yuling Zhao, Yongchun Huang, Yudong Su, Shoude Zhang

“…Further, ZJZC treatment in mice resulted in lower expression of MAPK1 protein and increased expression of PPAR-α protein, which have been shown to be strongly associated with HLP. Conclusions: This study showed that ZJZC contains various active ingredients and can modulate multiple targets and pathways associated with HLP, providing evidence at the molecular level for its clinical application in the treatment of HLP.…”
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Leveraging two-dimensional pre-trained vision transformers for three-dimensional model generation via masked autoencoders by Muhammad Sajid, Kaleem Razzaq Malik, Ateeq Ur Rehman, Tauqeer Safdar Malik, Masoud Alajmi, Ali Haider Khan, Amir Haider, Seada Hussen

“…On the other hand, the low availability of 3D datasets significantly impedes learning high-quality 3D features because of the high data processing cost. We present a strong multi-scale MAE prior training architecture that uses a trained ViT and a 3D representation model from 2D images to let 3D point clouds learn on their own. …”
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Expression and correlation of endoglin, sEndoglin, and MMP-14 on preeclampsia placenta by Febriana Catur Iswanti, Ninik Mudjihartini, Reni Paramita, Yuditiya Purwosunu, Ani Retno Prijanti

“…All parameters showed a gradual decrease with advancing gestational age. sEndoglin and MMP-14 demonstrated a strong positive correlation (r = 0.658, p < 0.001), while endoglin and MMP-14 exhibited a moderate positive correlation (r = 0.554, p < 0.001). …”
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Climatic Factors Influencing Aleppo Pine Sap Flow in Orographic Valleys Under Two Contrasting Mediterranean Climates by Ana M. Sabater, José Antonio Valiente, Juan Bellot, Alberto Vilagrosa

“…Future research will be essential to confirm forest acclimatisation in the transitional dry to semi-arid forest ecosystems predicted by global climate change projections, given their potential to strongly alter ecosystem function and water cycles.…”
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ANALYSIS OF A GENETIC COLLECTION OF TOMATO CULTIVARS AND HYBRID FORMS FOR RESISTANCE TO LEAF MOLD USING DNA MARKERS by I. N. Shamshin, M. V. Maslova, Y. V. Gryazneva

“…Six out of seven hybrids demonstrated a high level of resistance to the pathogen, which is con­firmed by the originators’ data. A strong lesion was noted on the leaves of only one hybrid. …”
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Association between colorectal cancer and arthritis among Americans in 2005–2016 by Zhongbo Hou, Niping Qin, Yanlin He, Jiang Chen, Yibo Cao, Wei Xie, Tianbao Xiao

“…Conclusion This study found that arthritis had a strong association with the occurrence of CRC, providing ideas and strategies for its early detection.…”
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Artificial Intelligence in Pediatric Epilepsy Detection: Balancing Effectiveness With Ethical Considerations for Welfare by Marina Ramzy Mourid, Hamza Irfan, Malik Olatunde Oduoye

“…Results AI systems have demonstrated strong potential in diagnosing and monitoring pediatric epilepsy, often matching clinical accuracy. …”
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Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives by Haixiao Jiang, Wei Zeng, Fei Zhu, Xiaoli Zhang, Demao Cao, Aijun Peng, Hongsheng Wang

“…Furthermore, we observed strong positive connections between bacteria enriched in the HE group and levels of systemic inflammation. …”
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Multivalent Neuroprotective Activity of <i>Elettaria cardamomum</i> (Cardamom) and <i>Foeniculum vulgare</i> (Fennel) in H₂O₂-Induced Oxidative Stress in SH-S... by Himadri Sharma, Hyewon Yang, Niti Sharma, Seong Soo A. An

“…Conclusion: Overall, the extracts provided better neuroprotection than the pure compounds in cellular assays and displayed strong anti-Aβ fibrilization activity.…”
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Analysis of Volatile Components and Key Aroma Components in Dianhong Congou Black Tea Produced by Variable Temperature Fermentation by WANG Yanyan, LIU Zhiwei, YAN Huiting, LU Jianwei, HE Yamei, GAO Jun, BAI Bing, LU Liping

“…Using the cutoff of OAV > 1, 152 key aroma compounds were identified from the five samples. β-Ionone, linalool and geraniol may contribute to the strong sweet floral aroma of DCT fermented at 35 ℃/3 h + 25 ℃/3 h. …”
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Cool topoclimates promote cold-adapted plant diversity in temperate mountain forests by Borderieux, Jeremy, De Lombaerde, Emiel, De Pauw, Karen, Sanczuk, Pieter, Vangansbeke, Pieter, Vanneste, Thomas, De Frenne, Pieter, Gégout, Jean-Claude, Serra-Diaz, Josep

“…Climate strongly influences the composition and diversity of forest plant communities. …”
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A remarkable permeability enhancement of Ni1−xZnxFe2O4 (x = 0.65 and 0.70), using a multi-compound calcined additive by S. Shatooti, M. Mozaffari

“…The results represent that there is a strong entanglement between composition, additive and/or sintering conditions. …”
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Seasonal and Gender Differences in Presence of Rickettsia felis and Blood meals Provide Additional Evidence of a Vector Role for Mosquitoes by Jilei Zhang, Guangwu Lu, Patrick John Kelly, Chengming Wang

“…For 1,088 female mosquitoes, 31% of them n=336 were positive for blood meal and 7% n=77 carried R. felis DNA. In a strong contrast, none of the 216 male mosquitoes were positive for blood meal but two males were positive for Rickettsia. …”
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Forecasting particulate matter concentration using nonlinear autoregression with exogenous input model by M.I. Rumaling, F.P. Chee, H.W.J. Chang, C.M. Payus, S.K. Kong, J. Dayou, J. Sentian

“…Four performance indicators, namely root mean square error, mean absolute error, index of agreement and fractional bias are reported.FINDINGS: Results from principal component analysis show that five variables including wind direction index, relative humidity, ambient temperature, concentration of nitrogen dioxide and concentration of ozone strongly contribute to the variation of PM10 concentration.  …”
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Paraspinal muscle volume and fatty infiltration after circumferential minimally-invasive deformity correction by John Paul G. Kolcun, Ryan M. Kelly, Bradley L. Kolb, Dustin H. Kim, Alireza Borghei, John E. O'Toole, Richard G. Fessler

“…Preoperative muscle volumes were strongly correlated with postoperative volumes. Conclusions: In this pilot series, paraspinal and psoas muscle volumes were preserved after circumferential MIS deformity correction. …”
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Spatiotemporal models with confounding effects: application on under-five mortality across four sub-Saharan African countries by Haile Mekonnen Fenta, Haile Mekonnen Fenta, Ding-Geng Chen, Ding-Geng Chen, Temesgen T. Zewotir, Najmeh Nakhaei Rad

“…The higher the proportion of these covariates, the lower is the prevalence of childhood mortality.ConclusionThis study revealed evidence of strong spatial, temporal, and interaction effects that influence under-five mortality risk across districts. …”
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High-Performance Hydrogen Sensing at Room Temperature via Nb-Doped Titanium Oxide Thin Films Fabricated by Micro-Arc Oxidation by Chilou Zhou, Zhiqiu Ye, Yue Tan, Zhenghua Wu, Xinyi Guo, Yinglin Bai, Xuying Xie, Zilong Wu, Ji’an Feng, Yao Xu, Bo Deng, Hao Wu

“…Among the fabricated samples, NTO thin film prepared at Nb₂O₅ concentration of 6 g/L (NTO-6) showed the best performance, with a broad detection range, excellent sensitivity, rapid response, and good specificity to hydrogen. A strong linear relationship between response values and hydrogen concentration (10–1000 ppm) highlights its potential for precise hydrogen detection. …”
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Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study by Feng S, Wang Y, Liu S, Zhang Y, He L

“…Genetic Instrument Selection was performed to identify valid instrumental variables, ensuring their independence from confounders and strong association with the exposure. Sensitivity analyses were conducted to ensure the robustness of the findings.Results: Forward MR analysis identified three brain networks (Pheno20, Pheno38, Pheno44) significantly associated with endometriosis risk (P FDR < 0.05). …”
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Cross-cultural Adaptation, Translation, and Validation of Gujarati Version of Neck Disability Index in Patients with Chronic Neck Pain by Shlesha Vaidya, Shreya Vaid

“…In phase II, the NDI-G showed strong psychometric properties. The translated version of the scale showed high internal consistency (Cronbach α = 0.82) and excellent test–retest reliability (Intra-class correlation coefficient = 0.982). …”
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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, the number of MITF+ monocytic (MO)-MDSCs was examined in human tumor tissues or tumor-free lymph nodes by immunohistochemistry (IHC).Results The expression of MITF was strongly increased in MO-MDSCs from tumors of breast cancer-bearing mice compared with polymorphonuclear MDSCs. …”
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