Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…Results: Treatment with the extract contributed to a significant reduction in the release of nitric oxide and reactive oxygen species in the ethanol-treated HepG2 cells; promoted the elevated expression of superoxide dismutase, catalase, and glutathione, indicating enhanced antioxidant defenses; and showed strong free radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl radicals. …”
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Influences of multi-pass friction stir alloying on characterization of AZ91D alloy-based dual reinforcement bio-ceramic nano-composites by Surendra Kumar Patel, Guoxin Dai, Lu Liu, Zhen Sun, Lei Shi

“…After 3-passes FSP average grain diameter of the composite C (1.61 μm) was smaller than that of composite A (1.86 μm) and composite B (1.63 μm), because of the strong shear deformation and generated friction heat, which occurred via dynamic recrystallization between grains in the processed zones. …”
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Promoting Internal Armed Conflict Resolution and Peacebuilding: The Case of the US–Colombia Relations (Part I) by A. A. Manukhin

“…The author shows that the forms and the scope of the U.S. assistance to the Colombian government were strongly linked to the evolution of both the situation in that country and the strategic priorities of the US foreign policy in general. …”
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Low-dose radiation ameliorates PM2.5-induced lung injury through non-canonical TLR1/TLR2-like receptor pathways modulated by Akkermansia muciniphila by Li Wang, Zhipeng Li, Huan He, Lijing Qin, Weiqiang Xu, Hongyuan Tian, Rongrong Liu, Xinru Lian, Wen Li, Yali Qi, Zhicheng Wang

“…However, the TLR1 and TLR2 continuously increased after LDR, indicating the downstream non-canonical TLR1/TLR2 pathway of Akk was activated to blunt the pro-inflammation of PM2.5. Our results strongly indicate that LDR-induced activation of gut Akk-dependent non-canonical TLR1/TLR2-like receptor pathway ameliorates lung injury and inflammation resulted from PM2.5.…”
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CRISPR/Cas9, a universal tool for genomic engineering by A. V. Smirnov, A. M. Yunusova, V. A. Lukyanchikova, N. R. Battulin

“…CRISPR/Cas9 proved to be especially useful in pronuclear microinjections of farm animals as well, having strong impact on biotechnology. In addition, we review Cas9-augmented genetic screens that allow an unbiased search for new genes and pathways involved in a plethora of biological aspects, owing to Cas9 efficiency and versatility. …”
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Healthcare consumers' perceptions of incentive-linked prescribing: A scoping review. by Muhammad Naveed Noor, Haider Safdar Abbasi, Nina van Der Mark, Zahida Azizullah, Janice Linton, Afifah Rahman-Shepherd, Amna Rehana Siddiqui, Mishal Sameer Khan, Rumina Hasan, Sadia Shakoor

“…HCCs perceived several hazards linked to ILP such as a lack of trust in physicians and the healthcare system, the prescribing of unnecessary medications, and the negative effect on physicians' reputations in society. In addition to strong regulatory controls, it is critical that physicians self-regulate their behaviour, and publicly disclose if they have any financial ties with pharmaceutical companies. …”
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Sonographic Assessment of Intravascular Fluid Estimate (SAFE) Score by Using Bedside Ultrasound in the Intensive Care Unit by Keith Killu, Victor Coba, Dionne Blyden, Semeret Munie, Darlene Dereczyk, Pridvi Kandagatla, Amy Tang

“…Results. 61 patients in the ICU were evaluated. 21 (34.4% of total) patients diagnosed with hypovolemia, and their ultrasound volume score was −4 in 14 (66.7%) patients, −3 in 5 (23.8%) patients, and 0 in 2 (9.5%) patients (p<0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and −1 in 1 (5.6%) patient (p<0.001). 22 (36.1% of total) patients diagnosed with hypervolemia, and their ultrasound volume score was +4 in 4 (18.2%) patients, +3 in 15 (68.2%) patients, and  + 1 in 1 (4.6%) patient (p<0.001). We found a strong association between standard measures and the ultrasound score (p<0.001). …”
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Identifying the healthy places to live in Australia with a new environmental quality health index by Shuang Zhou, Zhihu Xu, Wenzhong Huang, Yao Wu, Rongbin Xu, Zhengyu Yang, Pei Yu, Wenhua Yu, Tingting Ye, Bo Wen, Shanshan Li, Yuming Guo

“…Results: Validation showed strong model performance (R-squared = 83.53 %, 75.55 %, and 52.44 % for EQHI-all cause, EQHI-CVD, and EQHI-Resp). …”
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Design and assessment of lipase-CuO nanoparticle conjugates for enhanced antimicrobial efficacy against clinical pathogens by Eman M. Handak, Dina H. Amin, Mai M. Elhateir

“…Copper oxide (CuO) nanoparticles were characterized using visual indication of greenish color formation, UV-vis spectrum analysis which revealed a strong peak at 300 nm. Also, CuO nanoparticles appeared as distinct, well-dispersed spherical particles with average size of 71.035 nm using TEM, while conjugate appears as large protein molecules linked to the nanoparticles. …”
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Opportunities for promoting open data in the Caribbean through biobanks by Sushant Saluja, Simon G. Anderson

“…This article highlights the challenges of developing biobanks, including ensuring sufficient sample storage and data security, and the need for strong governance. It recommends solutions that involve regional collaboration, stakeholder engagement and increased investment in infrastructure. …”
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Tumour DNA methylation markers associated with breast cancer survival: a replication study by Elaheh Zarean, Shuai Li, Ee Ming Wong, Enes Makalic, Roger L. Milne, Graham G. Giles, Catriona McLean, Melissa C. Southey, Pierre-Antoine Dugué

“…In fully-adjusted models, strong associations were observed for a CpG in PRAC2 (per standard deviation [SD], HR = 1.67, 95%CI: 1.24–2.25) and a signature based on 28 CpGs developed using elastic net (per SD, HR = 1.48, 95%CI: 1.09–2.00). …”
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Gravitational Lensing of Charged Ayon-Beato-Garcia Black Holes and Nonlinear Effects of Maxwell Fields by H. Ghaffarnejad, M. Amirmojahedi, H. Niad

“…In this paper we study weak and strong gravitational lensing of light rays by seeking effects of NEM fields counterpart on image locations and corresponding magnification. …”
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Coping with sand and dust storms: Developing and validating of an adaptation assessment tool by Shiva Salehi, Ali Ardalan, Abbas - Ostadtaghizadeh, Armin Zareiyan, Gholamreza Garmaroudi, Abbas Rahimiforoushani

“…This tool can quantitatively measure society's adaptability to dust. With its strong validity and reliability, the tool can identify both the weakness and strengths of a society's adaptation to dust, compare the level of adaptation across different societies, and determine trends within a society. …”
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<i>Allosaurus europaeus</i> (Theropoda: Allosauroidea) Revisited and Taxonomy of the Genus by André Burigo, Octávio Mateus

“…The presence of <i>Allosaurus</i> in Portugal is strong evidence for a North America–Europe Late Jurassic dispersal, later supported by other taxa. …”
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Associations between subjective and objective measures of stress and load: an insight from 45-week prospective study in 189 elite athletes by Kristina Drole, Mojca Doupona, Kathrin Steffen, Kathrin Steffen, Aleš Jerin, Aleš Jerin, Armin Paravlic, Armin Paravlic

“…In cases where moderate to strong associations exist, subjective measures might serve as a reliable substitute for objective ones, making the monitoring process more time- and cost-efficient.…”
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Exploring Seasonality Indices for Low-Flow Analysis on Tibagi Watershed (Brazil) by Alexandre Sokoloski de Azevedo Delduque de Macedo, Michael Männich

“…The results indicate that, despite the watershed not presenting a strong seasonality, there is a tendency for low-flow discharges to concentrate in certain months, notably in August, September, and October. …”
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Metabolic consequences and nailfold capillary changes in children with familial Mediterranean fever by Ahmed S. Abo Hola, Rania S. El Zayat, Wafaa Ahmed Shehata, Mai I. Elashmawy, Noha E. Khalaf, Heba M. S. El Zefzaf

“…HOMA-IR showed positive correlations with TC, non-HDL-C, CRI I, and AC; however, NC changes were strongly connected with disease duration and SAA. Conclusions Insulin resistance, alterations in serum lipids and atherogenic indices, and NC changes significantly endure in children with FMF during attack-free periods compared to controls, with more prominence during acute attacks. …”
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Multi-Objective Simulated Annealing for Efficient Task Allocation in UAV-Assisted Edge Computing for Smart City Traffic Management by Ahmed Shamil Mustafa, Salman Yussof, Nurul Asyikin Mohamed Radzi

“…While some limitations exist in real-world applications, this work provides a strong foundation for optimizing resource utilization in smart city systems that integrate multiple computational tasks.…”
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Plant Growth Promoting Rhizobacteria (PGPR): Reports on Their Colonization, Beneficial Activities, and Use as Bioinoculant by Dew Biswas, Amit Kumar Chakraborty, Vikas Srivastava, Arunava Mandal

“…Several soil resident microorganisms interact strongly with neighboring plants and promote the growth and development of those plants through various means. …”
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Ecotope-Based Entomological Surveillance and Molecular Xenomonitoring of Multidrug Resistant Malaria Parasites in Anopheles Vectors by Prapa Sorosjinda-Nunthawarasilp, Adisak Bhumiratana

“…This enables the EES to encompass mosquito collection and identification, salivary gland DNA extraction, Plasmodium- and species-specific identification, molecular marker-based PCR detection methods for putative drug resistance genes, and data management. The EES establishes strong evidence of Anopheles vectors carrying MDR P. vivax in infection pockets epidemiologically linked with other data obtained during which a course of follow-up treatment of the notified P. vivax patients receiving the first-line treatment was conducted. …”
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