Evaluating the efficacy of vestibular rehabilitation therapy on quality of life in persistent postural-perceptual dizziness: the role of anxiety and depression in treatment outcome... by Khalid A. Alahmari, Sarah Alshehri

“…Age was also found to correlate with increased dizziness severity (p < 0.001), although this was not as strong as the correlation of symptom duration (longer duration correlating with increased dizziness severity; p < 0.01), anxiety (r = −0.45, p = 0.002) and depression (r = −0.51, p < 0.001) (both significantly associated with poorer outcomes especially with reference to VRT) emerging as independent correlates of reduced effectiveness of treatment.ConclusionsThis study revealed the benefit of VRT in patients with PPPD on QoL and indicates the importance of identifying and treating psychological factors to improve the success of treatment for PPPD.…”
Get full text

CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models by Maia Cabrera, Romina Armando, Ian Czarnowski, Patricio Chinestrad, Ramiro Blanco, Alejandra Zinni, Daniel Gómez, Diego L. Mengual Gómez, Pablo Lorenzano Menna

“…ADMET studies further highlighted their strong potential as lead PKM2 inhibitors for GBM treatment.Molecular dynamics (MD) simulations and post-MD analyses, including Dynamic Cross-Correlation Maps (DCCM), Probability Density Function (PDF), and Free Energy Landscape (FEL), confirmed the stability of the protein-ligand interactions and highlighted critical residues at the dimer-dimer interface. …”
Get full text

Pesticide pollution status in cocoa plantation soil by E. Atuanya, W. Aborisade

“…Composition quotients values indicate that most of the observed organochlorine pesticides residues were products of historical usage. There were strong correlations among the total organic carbon contents of soils and the total organochlorine pesticides compounds. …”
Get full text

Visual Gradation of Biological Soil Crust Development: A Simple and Effective Recording Method by Xinyu Zhang, Ping He, Jie Xu

“…Developmental indicators in various grades of cyanobacterial and moss crusts showed a moderate (30% < CV < 100%) to strong (CV > 100%) variation, highlighting the importance of environmental heterogeneity at the regional scale. …”
Get full text

A Spatial&#x2013;Temporal Difference Aggregation Network for Gaofen-2 Multitemporal Image in Cropland Change Area by Chuang Liu, Liyang Bao, Zhiqi Zhang

“…The accurate monitoring of cropland utilizing remote sensing data provides a strong technical support for the protection of cropland resources. …”
Get full text

Vibration and Sound Transmission Performance of Sandwich Panels with Uniform and Gradient Auxetic Double Arrowhead Honeycomb Cores by Qing Li, Deqing Yang

“…The results indicated that the vibrating mode shapes and deformations of the DAH sandwich models were strongly affected by the patterned gradient metamaterials. …”
Get full text

Symptomatic vigabatrin‐associated MRI toxicity is associated with simultaneous hormonal therapy among patients with infantile spasms by Rujuta Sathe, Gyaneshwar Shrestha, Aria Terango, David Tabibzadeh, Rajsekar R. Rajaraman, Hiroki Nariai, Shaun A. Hussain

“…Symptomatic VABAM was strongly associated with simultaneous exposure to hormonal therapy (p = 0.001). …”
Get full text

Risk Prediction for Ship Encounter Situation Awareness Using Long Short-Term Memory Based Deep Learning on Intership Behaviors by Jie Ma, Wenkai Li, Chengfeng Jia, Chunwei Zhang, Yu Zhang

“…Then, the long short-term memory network, which has a strong ability to model temporal dependency and complex patterns, is extended to establish the relationship. …”
Get full text

Fetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects by Bruno C. Menarim, DVM, PhD, Chan Hee Mok, PhD, Kirsten E. Scoggin, PhD, Alexis Gornik, DVM, Emma N. Adam, DVM, PhD, Shavahn C. Loux, PhD, James N. MacLeod, VMD, PhD

“…Chondrocyte-treated repair tissue exhibited strong proteoglycan and COL2 staining but poor integration to the adjacent bone. …”
Get full text

Association of leukocyte elastase in semen and seminal plasma with sperm parameters and pregnancy outcomes in male fertility by Mausumi Das, Maha Gumssani, Julia Mullaney, Ralf Henkel, Suks Minhas, Marie Claire Aquilina, Channa N Jayasena

“…Overall, we did not identify a strong association between LE levels and pregnancy or fertilization rates. …”
Get full text

Prenatally Diagnosed Cardiac Tumors and Tuberous Sclerosis Complex: A Single-Center Experience by Matija Bakoš, Dora Jelinek, Ana Ćorić Ljoka, Nada Sindičić Dessardo, Dalibor Šarić, Ruža Grizelj

“…Conclusion: While CRs are typically benign and regress spontaneously, their strong association with TSC highlights the importance of early diagnosis and family counseling. …”
Get full text

Consequences of changing regional integration on environmental development, agricultural markets, and food security by L.A. Omarbakiyev, S.M. Kantarbayeva, A.K. Nizamdinova, S.T. Zhumasheva, G.Zh. Seitkhamzina, A. Saulembekova

“…In the first stage, statistical information was collected; in the second stage, a correlation analysis was carried out; and in the third stage, a survey of 40 experts was conducted.FINDING: The data obtained indicate that the efficiency of Kazakhstan’s agricultural production strongly and directly depends on the level of the country’s integration into the united Eurasian Economic Union market. …”
Get full text

Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy by Pei-Pei Liu, Xin-Yue Yu, Qing-Qing Pan, Jia-Jun Ren, Yu-Xuan Han, Kai Zhang, Yan Wang, Yin Huang, Tao Ban

“…Results: Network analysis identified 129 drugs associated with SCM, which were refined to 14 drug candidates based on strong network predictions, proven anti-infective effects, suitability for ICU use, and minimal side effects. …”
Get full text

Endoscopic Epidurolysis for the Management of Chronic Spinal Pain: A Delphi-Based Italian Experts Consensus by Matteo Luigi Giuseppe Leoni, Felice Occhigrossi, Michael Tenti, William Raffaeli, ISAL Research Study Group

“…A two-round Delphi process was implemented, with consensus defined as at least 70% agreement on a 7-point Likert scale (agree or strongly agree). Statements that did not reach consensus in the first round were rephrased and resubmitted in the second round. …”
Get full text

Dietary Patterns and Fitness Level in Mexican Teenagers by César Estrada-Reyes, Patricia Tlatempa-Sotelo, Roxana Valdés-Ramos, María Cabañas-Armesilla, Rafael Manjarrez-Montes-de-Oca

“…Nowadays, the term “physical fitness” has evolved from sports performance to health status, and it has been considered a strong predictor of cardiovascular disease. In this sense, test batteries have been developed to evaluate physical fitness such as the ALPHA-FIT battery. …”
Get full text

Schoolscaping in a Multilingual Area: An Example of a Hungarian College in Western Ukraine by Váradi Krisztián, Hires-László Kornélia, Máté Réka

“…Based on the results, the Rákóczi College follows a strong bilingual tradition by making everything available in at least two languages (Ukrainian and Hungarian), but the bottom-up domain is also subject to monolingualism. …”
Get full text

Assessing Human Role in Lateral Erosion and Lateral Extension of Gamasiab River in Bistoon Plain by Mahmoud Alaee Taleghani, Farshad Haseli, Majid Ahmadi Molaverdi

“…This matter has caused the banks of Gamasiyab in few meander strongly wearing out and retreat 30 meters. However, to reach to this aim, the geometrical parameters of 15 meanders that human played an important role in erosion them have been compared with another 19 meanders in a period of 24 years. …”
Get full text

Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis by Mengling Wang, Feng Zeng, Fengling Ning, Yinhang Wang, Shilin Zhou, Jiaqi He, Cong Li, Cong Wang, Xiaolin Sun, Dongliang Zhang, Jisheng Xiao, Ping Hu, Svetlana Reilly, Hong Xin, Xudong Xu, Xuemei Zhang

“…Ceria nanoparticles (CeNP-PEG) with strong ROS scavenging and anti-inflammatory activities have been applied for mitochondrial oxidative stress and inflammatory diseases. …”
Get full text

Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema by Ioana Damian, Simona Delia Nicoara

“…In the PDR-DMO group, RPE thickness was decreased in almost all quadrants (p<0.001); in the NPDR-DMO group, only the central minimum and central maximum values of the RPE thickness were significantly different from the control group. We did not find any strong correlation between BCVA and the thickness of the retinal layers. …”
Get full text

Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling by Mandy O. J. Grootaert, Alessandra Pasut, Jana Raman, Steven J. Simmonds, Bram Callewaert, Ümare Col, Mieke Dewerchin, Peter Carmeliet, Stephane Heymans, Elizabeth A. V. Jones

“…NicheNet analysis on the single cell transcriptomic data revealed little signalling from the ECs to the mural cells; instead, mural cells signalled strongly to ECs. Mechanistically, pericyte dysfunction induces an EC growth arrest via TNFα-dependent paracrine signalling and downstream signalling through STAT1. …”
Get full text