Developing transcriptomic biomarkers for TAVO412 utilizing next generation sequencing analyses of preclinical tumor models by Ying Jin, Peng Chen, Huajun Zhou, Guangmao Mu, Simin Wu, Zhengxia Zha, Bin Ma, Chao Han, Mark L. Chiu, Mark L. Chiu

“…TAVO412 demonstrated strong in vivo tumor growth inhibition in 23 cell-line derived xenograft (CDX) models representing diverse cancer types, as well as in 9 patient-derived xenograft (PDX) lung tumor models.MethodsUsing preclinical CDX data, we established transcriptomic biomarkers based on gene expression profiles that were correlated with anti-tumor response or distinguished between responders and non-responders. …”
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Behavioural Risk Factors, Hypertension Knowledge, and Hypertension in Rural India by Eslavath Rajkumar, John Romate

“…The emergence of hypertension and other cardiovascular diseases are strongly related to various risk factors. Knowledge about hypertension and related risk factors is often stressed on their utility in prevention and management of the disease. …”
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Higher Education and the Challenges of Network Society: Philosophical Themes by B. V. Markov

“…However, the faculty body, especially in the Humanities sphere, expressed strong criticism. The argument is that digital technologies do not solve pedagogic problems. …”
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Solution-Based Ultraviolet Photodiode with ZnO Nanoparticle/Poly(3,4-Ethylenedioxythiophene) Polystyrene Sulfonate Heterojunction and Negative Capacitance by Jin Li, Xin Chang, Shunpu Li, Yi Zhang, Daping Chu

“…First, solution-based films of ZnO NPs and PEDOT:PSS were prepared, and their optical and electrical properties were individually characterized. Strong optical absorption by ZnO NPs for wavelengths below 400 nm was experimentally observed, while absorption by PEDOT:PSS in the same wavelength range is trivial. …”
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Assessing the impact of waste picking on musculoskeletal disorders among waste pickers in Mumbai, India: a cross-sectional study by Praveen Chokhandre, Shrikant Singh

“…Preventive measures and treatment to minimise the burden of MSDs among waste pickers are strongly recommended.…”
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Prediction of the Location of Concealed Pluton on the Spatial Variation Characteristics of Volatile Matter in Coal Seams by Yihao Li, Jingui Zhao, Wensheng Li

“…The results indicate the following: (1) In the central region of the exploration area, from No. 9 to No. 8 to No. 6 to No. 2 to No. 02, the contours of volatiles in each coal seam exhibit a ring pattern, with the size of the ring and the size of the volatiles change regularly. This pattern strongly suggests that the concealed pluton is developed in the underlying layer of the coal seam. (2) According to the linear fitting of the relevant data, it is predicted that the concealed pluton is located at a depth of 65.4 m below the No. 9 coal seam. …”
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Recent advances in applications of green nanocomposites in enhanced oil recovery: a comprehensive review of different characterization methods and effective parameters by Meysam Hemmati, Yaser Ahmadi

“…In some cases, the contact angle dropped down from 161 to 28° or from 151 to 14°, which led to the creation of strong hydrophilic (water-wet) systems. The interfacial tension is also greatly diminished according to the modifying character of NCs, so that causes a reduction in IFT of more than 33.8 mN/m. …”
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Daily Functionality of People with Low Vision: The Impact of Visual Acuity, Depression, and Life Orientation—A Cross-Sectional Study by Mara Gkioka, Stavroula Almpanidou, Niki Lioti, Diamantis Almaliotis, Vasileios Karampatakis

“…Optimism as a personality characteristic did not factor into the prediction model for daily functionality, but it showed a strong correlation with lower levels of depressive symptoms. …”
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Effect Of Magnesium Perchlorate Content on the Mechanical, Thermal Stability, and Dielectric Properties of Plasticized PMMA/PVC-g-PMMA Electrolytes by Nguyen Thi Kim Dung, Nguyen Thi Dieu Linh, Do Quang Tham, Nguyen Thuy Chinh, Man Minh Tan, Tran Thi Mai, Nguyen Thi Thu Trang, Do Minh Thanh, Nguyen Quang Tung, Thai Hoang

“…With increasing the Mg salt concentration, Young’s modulus and tensile strength of the GPBEs strongly decreased. Interestingly, the elongation at break of the GPBEs was higher than that of neat (undoped) GPBE and achieved the highest value of 215% at the salt content of 20 wt.%. …”
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Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma by Guiyu Kang, Hui Song, Lei Bo, Qi Liu, Qiang Li, Jingtan Li, Pan Pan, Jingting Wang, Yanfei Jia, Haiji Sun, Xiaoli Ma

“…Furthermore, α5-nAChR expression was strongly linked to pSTAT3, SOX2 and M2 macrophage marker CD206 expression and negatively correlated with M1 macrophage marker CD86 expression in vivo. …”
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Dissolved organic matter and its correlation with phytoplankton abundance for monitoring surface water quality by O. Cahyonugroho, S. Hariyanto, G. Supriyanto

“…., had the highest abundance at Stations 1, 3, and 4, respectively. A strong correlation between dissolved organic matter analysis and phytoplankton abundance led to the usage of these methods for monitoring surface water quality.…”
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3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Speci... by Yang Li, Xude Wang, Baoyu Yang, Haozhen Wang, Zhenzhong Ma, Ziyin Lu, Xiuli Lu, Bing Gao

“…Cells infected with Ad-LacZ exhibited a rapid and strong activation of ATF6 and p38, peaking at 3 h after TM exposure. …”
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The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

“…Conclusions: Elevated IL-6 levels and specific gene polymorphisms are strongly associated with preterm delivery risk, with IL-8 concentrations correlating with systemic inflammation and histologic chorioamnionitis. …”
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NIGWO-iCaps NN: A Method for the Fault Diagnosis of Fiber Optic Gyroscopes Based on Capsule Neural Networks by Nan Lu, Huaqiang Zhang, Chunmei Dong, Hongtao Li, Yu Chen

“…It effectively confirms that the method in this paper is capable of efficient and accurate fault diagnosis of FOG and has strong generalization ability.…”
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A descriptive study of smoking, socioeconomic position, and health-related behaviors in urban Colombia by Valentina Guatibonza-García, Sofía Gnecco-González, Agustín Pérez-Londoño, Carolina Betancourt-Villamizar, Carlos O. Mendivil

“…Conclusion The worldwide trend towards a reduction in smoking seems to have been reversed in Colombia, smoking is increasing fast in disadvantaged population segments. Strong tobacco control policies should focus on men with less income and lower education. …”
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Design of a humanized CD40 agonist antibody with specific properties using AlphaFold2 and development of an anti-PD-L1/CD40 bispecific antibody for cancer immunotherapy by Kun Du, He Huang

“…This novel anti-PD-L1/CD40 bispecific antibody holds potential for strong anti-tumor therapeutic efficacy by selectively restricting CD40 stimulation in tumors.…”
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Development and validation of a prognostic nomogram for predicting of patients with acute sedative-hypnotic overdose admitted to the intensive care unit by Guo Tang, Tianshan Zhang, Ping Zhang, Sha Yang, Tao Cheng, Rong Yao

“…The nomogram demonstrated strong predictive performance with an area under the curve (AUC) of 0.858 (95% CI: 0.788–0.927) in the training set and 0.845 (95% CI: 0.757–0.933) in the validation set. …”
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Secondary School Teachers’ Conceptions of Teaching Science Practical Work through Inquiry-Based Instruction by Tomas Shivolo, Hamza Omari Mokiwa

“… Contemporary science teaching pedagogy in Namibia places a strong emphasis on fostering inquiry-based instruction and practical work in secondary school science education. …”
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Daily activity, mood, and quality of life in colorectal cancer patients with chemotherapy‐induced peripheral neuropathy: A mediation effect analysis by Ling‐Chun Lu, Shiow‐Luan Tsay, Sou‐Yi Chang, Chung‐Ming Chen, Chieh‐Yu Liu

“…Although the management of CIPN and RDA can prevent irreversible functional problems, enhancing the adaption of mood disturbance can strongly promote their QoL.…”
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Roles of core nosZ denitrifiers in enhancing denitrification activity under long-term rice straw retention by Shijie Zhang, Shijie Zhang, Mengyao Hou, Mengyao Hou, Bing Li, Bing Li, Panfeng Guan, Panfeng Guan, Qing Chi, Qing Chi, Hao Sun, Hao Sun, Hangbo Xu, Hangbo Xu, Dongjie Cui, Dongjie Cui, Yupan Zhu, Yupan Zhu

“…The denitrification process is known to contribute to soil nitrogen (N) loss, which is strongly affected by fertilization strategies; however, the effects of distinct straw retention modes on soil denitrification activity have rarely been discriminated and the underlying mechanisms remain unclear. …”
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