Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation by Katsuya Kobayashi, Toshio Suda, Haruhiko Manabe, Ichiro Miki

“…Compared to leflunomide, PDE4 inhibitors more strongly suppressed IL-12 production and the increase in myeloperoxidase activity. …”
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Predefined-Time <italic>H</italic> _&#x221E; Cooperative Control for Multi-Robot Systems Based on Adjustable Prescribed Performance Control and Adaptive Command Filter by Haitao Liu, Weichen Li, Xin Huang, Xuehong Tian, Qingqun Mai

“…Fourth, the predefined-time <inline-formula> <tex-math notation="LaTeX">$H_{\infty } $ </tex-math></inline-formula> coordinated formation controller for multi-robot systems (MRSs) is designed to achieve strong robustness to various disturbances. Finally, all the signals in the control system are bounded and converge within the predefined time, and the results of the virtual simulation experiments verify the validity and performance of the MRSs.…”
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Future Changes in Winter‐Time Extratropical Cyclones Over South Africa From CORDEX‐CORE Simulations by Sandeep Chinta, C. Adam Schlosser, Xiang Gao, Kevin Hodges

“…We utilized three regional climate models, each driven by three different global climate models that simulate both the current climate and a future climate experiencing strong human‐induced warming. From these, we assess changes in ETC frequency, track density, intensity, storm severity, and associated rainfall. …”
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Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost by Bo Zhang, Youyi Fong, Lauren Dang, Jonathan Fintzi, Shiyu Chen, Jing Wang, Nadine G. Rouphael, Angela R. Branche, David J. Diemert, Ann R. Falsey, Daniel S. Graciaa, Lindsey R. Baden, Sharon E. Frey, Jennifer A. Whitaker, Susan J. Little, Satoshi Kamidani, Emmanuel B. Walter, Richard M. Novak, Richard Rupp, Lisa A. Jackson, Chenchen Yu, Craig A. Magaret, Cindy Molitor, Bhavesh Borate, Sydney Busch, David Benkeser, Antonia Netzl, Derek J. Smith, Tara M. Babu, Angelica C. Kottkamp, Anne F. Luetkemeyer, Lilly C. Immergluck, Rachel M. Presti, Martín Bäcker, Patricia L. Winokur, Siham M. Mahgoub, Paul A. Goepfert, Dahlene N. Fusco, Robert L. Atmar, Christine M. Posavad, Jinjian Mu, Mat Makowski, Mamodikoe K. Makhene, Seema U. Nayak, Paul C. Roberts, Peter B. Gilbert, Dean Follmann, Coronavirus Variant Immunologic Landscape Trial (COVAIL) Study Team

“…Neutralizing antibody titer was a strong inverse correlate of Omicron COVID-19 in non-naïve individuals and a weaker correlate in naïve individuals, posing questions about how prior infection alters the neutralization correlate.…”
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Mechanical and durability properties of coal cinder concrete: Experimental study and GPR-based analysis by Ali Toghroli, Seyed Azim Hosseini, Farshid Farokhizadeh

“…Gaussian Process Regression (GPR) was employed to predict these properties, showing high accuracy with RMSE values ranging from 0.29 to 0.38 and Adjusted R² values between 0.85 and 0.92. The strong predictive performance of GPR highlights its applicability for modeling complex materials like HPC. …”
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Comparative In Vitro Effects of Calcineurin Inhibitors on Functional Vascular Relaxations of Both Rat Thoracic and Abdominal Aorta by Ashok Jadhav, Venkat Gopalakrishnan, Ahmed Shoker

“…In AA, (control: IC50 50 nM; Imax 100%) CsA (IC50 7 μM; (P<0.01) showed strong sensitivity to inhibit ACh-dependent vascular relaxation than Tac (IC50 215 nM (P<0.05); Imax 98%). …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“…Albumin, TP, C4, and transferrin showed lower initial values in DG than the SG, with a strong correlation with the total burned surface area (TBSA). …”
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Factors Affecting Maternal Behavior in Achieving Complete Basic Immunization for Toddlers Aged 12–23 in Banggai Laut Regency, Indonesia by Amrin Madolan, Ridwan M Thaha, Muhammad Syafar, Sudirman Nasir, Nurhaedar Jafar, A Arsunan Arsin

“…Results: Significant associations were found between complete basic immunization and good knowledge (p<0.000; OR=3.2), positive attitudes (p<0.000; OR=2.8), availability of healthcare facilities (p<0.000; OR=3.4), proximity to healthcare services (p<0.000; OR=3.7), supportive roles of healthcare workers (p<0.000; OR=2.9), and strong spousal support (p<0.000; OR=2.5). Maternal occupation showed no significant effect (p=0.379). …”
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Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis by Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, Benjamin Lefevre, Muhammad Farooq, Aurélien Jan, Christelle Manuel, Laurence Touami-Bernard, Catherine Lucas-Clerc, Valentine Genet, Hugues Gascan, Jean-Philippe Girard, Frédéric Chalmel, Lucie Lamontagne, Claire Piquet-Pellorce, Michel Samson

“…However, the IFNγ was strongly induced in WT mice with less profound expression in IL-33 KO mice demonstrating that endogenous IL-33 regulated IFNγ expression during L2-MHV3 hepatitis. …”
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Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

“…Although the aetiology remains uncertain, evidence is now growing that exposure to persistent organic pollutants during sensitive neurodevelopmental periods such as early life may be a strong risk factor, predisposing the individual to disease development later in life. …”
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Comparison of a combined torus tank with a composite isogrid support with existing design solutions by Andrii Diadiuk, Volodymyr Lipovskyi

“…On one hand, the design must be strong, rigid, and stable, while on the other, it must be as lightweight as possible. …”
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Some claim for the end of Botany… but what is Botany today? by Lorenzo Peruzzi

“…As a result, people may seek advice from “experts” who may not necessarily have a strong foundation in Botany. Similarly, botanical gardens are often perceived by the public as merely aesthetic spaces, akin to vegetable gardens or parks, rather than as scientifically-driven institutions. …”
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Emotional and psychological experiences of nursing students caring for dying patients: an explorative study at a national referral hospital in Uganda by Asha K. Nabirye, Ian G. Munabi, Aloysius G. Mubuuke, Sarah Kiguli

“…Abstract Background Caring for dying patients is associated with psychological trauma, strong emotions and enormous stress for nursing staff and nursing students who are reliable health care providers in such difficult situations. …”
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Phenotypic plasticity vs. local genetic adaptation: essential oil diversity of natural immortelle (Helichrysum italicum (Roth.) G.Don) populations along eastern Adriatic coast by Tonka Ninčević Runjić, Dejan Pljevljakušić, Marko Runjić, Martina Grdiša, Martina Grdiša, Zlatko Šatović, Zlatko Šatović

“…Results showed a significant and strong correlation between biochemical and bioclimatic distance, with 22.4% of biochemical differentiation between populations explained by bioclimatic distance. …”
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Novel Indices of Glucose Homeostasis Derived from Principal Component Analysis: Application for Metabolic Assessment in Pregnancy by Tina Stopp, Michael Feichtinger, Ingo Rosicky, Gülen Yerlikaya-Schatten, Johannes Ott, Hans Christian Egarter, Christian Schatten, Wolfgang Eppel, Peter Husslein, Martina Mittlböck, Andrea Tura, Christian S. Göbl

“…PCS1 was positively associated with fasting and dynamic parameters of insulin sensitivity (Matsuda index: r=0.93, p<0.001), whereas a strong negative association was observed for early, late, and total insulin response. …”
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Kinetics of Sphalerite Leaching by MnO₂-KI Oxidation System in Sulfuric Acid by Mladen Bugarčić, Aleksandar Jovanović, Dimitrije Anđić, Ivana Jelić, Milica Miletić, Branislav Marković, Miroslav Sokić

“…Traditional leaching techniques often rely on strong oxidizing agents, which can be wasteful and environmentally harmful. …”
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Knee rotation in patients with and without patellofemoral instability and its correlation with patellar tendon trochlear groove distance by Himanshu Gupta, Vineet Jain, Nilansh Kataria, Ashish Dutt Upadhyay, Pallav Mishra, Himanshu Kataria

“…Overall, the PTTG distance showed moderate to strong correlation with the external knee rotation as well as with lateralisation of patellar tendon insertion. …”
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Blinded by the Mind: Exploring the Hidden Psychiatric Burden in Glaucoma Patients by Jeniffer Jesus, João Ambrósio, Dália Meira, Ignácio Rodriguez-Uña, João Melo Beirão

“…Vision impairment is strongly associated with several psychiatric disorders, like depression, anxiety, and sleep problems. …”
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Efficacy of ultrasonography and mammography in detecting features of breast cancer by Sultan Abdulwadoud Alshoabi, Amal A. Alareqi, Moawia Gameraddin, Awadia Gareeballah, Kamal D. Alsultan, Amel F. Alzain

“…The sensitivity and specificity for each feature were calculated, and the receiver operating characteristic curve was used to measure the area under the curve for each feature on both modalities. Results: The strong compatibility between the two techniques was 87.1%, 94.29%, 66.92%, 79.85%, 77.56%, 77.18, and 79.84% for irregular shape, uncircumscribed, spiculated margins, tissue distortion, nipple retraction, skin thickening, and the presence of lymphadenopathy, respectively (P < 0.001). …”
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Prediction of the critical stress to crack initiation associated to the investigation of fatigue small crack by D. Marhabi, N. Benseddiq, G. Mesmacque, Z. Azari, J.M. Nianga

“…Hence, the considerations of small crack growth are strongly influencing the fatigue life of a component or structure…”
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