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4941
Mucocutaneous Adverse Events in Patients With Cancer Treated with the Highly Selective RET Kinase Inhibitor Selpercatinib (LOXO-292)
Published 2025-03-01“…A treatment algorithm was created for the most common MAEs: xerostomia managed with saliva and lubricants; mucositis with steroid rinses; rashes with topical steroids with or without topical ammonium lactate; periorbital edema with cold or caffeine compresses; and xerosis and pruritus with emollients. …”
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4942
Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans
Published 2025-02-01Get full text
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4944
Multi-dimensional outcomes following extracorporeal cardiopulmonary resuscitation
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4945
Case Reports: The core of practice-based evidence
Published 2019-07-01“…These standards are the CONSORT Statement [7] for reporting randomized trials, the STROBE guidelines for strengthening the reporting of observational studies in epidemiology [8], PRISMA for reporting items for systematic reviews and meta-analyses [9], the guidelines for reporting adverse events [10] and the ‘CARE Guidelines’ for the Consensus-based Clinical Case Reporting Guideline Development [2]. …”
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4946
RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study
Published 2023-05-01“…Enrichment analyses showed that “steroid receptor activity” and the “PI3K/AKT signaling pathway” were the most enriched biological process and signaling pathway, respectively. …”
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4947
Targeting of the G9a, DNMT1 and UHRF1 epigenetic complex as an effective strategy against pancreatic ductal adenocarcinoma
Published 2025-01-01“…Staining was semi-quantitatively scored, and overexpression was defined as moderate to strong positivity. The prognostic impact was assessed by correlating protein expression with patient survival. …”
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4948
Comparative Ethics of Modern Payment Models
Published 2023-01-01“…JAMA - Journal of the American Medical Association. 2015;314(14):1445-1446. doi:10.1001/jama.2015.8909 [28] Groeneveld IF, Goossens PH, van Meijeren-Pont W. Value-Based Stroke Rehabilitation: Feasibility and Results of Patient-Reported Outcome Measures in the First Year After Stroke. …”
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Activités artisanales sur la rive droite de la Vesle à Reims/Durocortorum
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4951
Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia
Published 2025-01-01“…BackgroundDexamethasone sodium phosphate (DSP) encapsulated in autologous erythrocytes (EryDex) was developed as an alternative to standard glucocorticoids in an effort to eliminate chronic steroid toxicity while preserving efficacy. The primary objective of this report is to describe the safety of long-term use of EryDex in treatment of pediatric patients with ataxia telangiectasia.MethodsThis is a post-hoc analysis of patients treated with EryDex for a minimum of 24 months in two prospective clinical trials. …”
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4955
Percutaneous coronary intervention vs. medical therapy in patients on dialysis with coronary artery disease in China
Published 2025-02-01“…The primary outcome was major adverse cardiovascular events (MACE), defined as a composite of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke. Secondary outcomes included all-cause death, the individual components of MACE, and Bleeding Academic Research Consortium criteria types 2, 3, or 5 bleeding. …”
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4956
Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis
Published 2025-03-01“…At a median follow-up of 17.2 months, mOS, mPFS, and TTP stood at 16.5, 6.1, and 6.8 months, respectively. …”
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First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study
Published 2025-01-01“…One hundred forty-two patients (32.6%) in our cohort would not have been eligible for the pivotal registrational trials owing to an Eastern Cooperative Oncology Group performance status of 2 or higher, autoimmune disease, active brain metastases, or steroid use. Most patients received carboplatin (96.8%) and atezolizumab (97.9%). …”
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4959
Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ...
Published 2022-07-01“…Median time to first dose of antibiotics was 3.2 hours (IQR 1.3–9.2). 80% received empirical parenteral cephalosporins. 55% ≥60 years and 31% of immunocompromised patients received anti-Listeria antibiotics. 21% received steroids. Of the 1471 patients, 20% had confirmed bacterial meningitis. …”
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Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
Published 2025-01-01“…Using paired single-cell RNA and epigenomic sequencing with Stereo-seq, we revealed two fibroblast subsets CAF-FAP and CAF-C7, whose spatial enrichment strongly correlated with the two stromal archetypes and opposing patient prognosis. …”
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