Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer by Jenny Ling-Yu Chen, Chun-Kai Pan, Li-Cheng Lin, Yu-Sen Huang, Tsung-Hsuan Huang, Shu-Jyuan Yang, Sung-Hsin Kuo, Yu-Li Lin

“…ATR inhibitor pretreatment decreased cell survival after irradiation by inhibiting DNA double-strand break repair, inducing mitotic cell death, and altering cell cycle progression. …”
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African Childhood “Reawakened”: Using Cultural Studies Theory in Understanding the Use of Symbolism in Camara Laye’s The African Child. by Johnson, Ocan, Lillian, Tindyebwa

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Analysis of drought and extreme precipitation events in Thailand: trends, climate modeling, and implications for climate change adaptation by José Francisco de Oliveira-Júnior, David Mendes, Helder Dutra Porto, Kelvy Rosalvo Alencar Cardoso, José Augusto Ferreira Neto, Emannuel Bezerra Cavalcante da Silva, Marlúcia de Aquino Pereira, Monica Cristina Damião Mendes, Bernardo Bruno Dias Baracho, Punyawi Jamjareegulgarn

“…In the R8.5 scenario, the number of consecutive dry days increased across the entire country. The WSDI stood out in both the R4.5 and R8.5 scenarios, with an increase in the duration of warm spells in Thailand. …”
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L’aqueduc du Gier : nouvelles données sur le pont-siphon de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon) by David Baldassari, François Blondel, Stéphane Gaillot

“…Its deck was 290 m long at the deck, it stood 18 m high at its central part and had 30 arches supported by 29 piers. …”
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Curcumin-Loaded Lipid Nanoparticles: A Promising Antimicrobial Strategy Against <i>Enterococcus faecalis</i> in Endodontic Infections by Sónia Ferreira, Liliana Grenho, Maria Helena Fernandes, Sofia A. Costa Lima

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The Role of Gut Microbiota in Hypertension Management - A Review by Alicja Kot, Marta Wojtczak, Natalia Myśliwiec, Adrian Różycki, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej

“…Animal studies using fecal microbiota transplantation (FMT) have provided strong evidence for a causal role of gut microbiota in blood pressure regulation. …”
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Pentraxin 3 Levels in Young Women with and without Polycystic Ovary Syndrome (PCOS) in relation to the Nutritional Status and Systemic Inflammation by Katarzyna Wyskida, Grzegorz Franik, Piotr Choręza, Natalia Pohl, Leszek Markuszewski, Aleksander Owczarek, Paweł Madej, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…Our results show that the decrease in PTX3 levels observed in obese is distorted in PCOS by microinflammation, and possibly, dysfunction of stroma adipose tissue and liver steatosis is reflected by enhanced insulin resistance.…”
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Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus by Brézellec, Pierre

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The impact of fruit and vegetable waste on economic loss estimation by B. Parsafar, M. Ahmadi, Gh.R. Jahed Khaniki, N. Shariatifar, A. Rahimi Foroushani

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Diagnostic Potential of CTRP5 and Chemerin for Coronary Artery Disease: A Study by Coronary Computed Tomography Angiography by Taha Okan, Cihan Altın, Caner Topaloglu, Mehmet Doruk, Mehmet Birhan Yılmaz

“…Receiver operating characteristic (ROC) analysis showed that a CTRP5 cutoff of 172.30 ng/mL had 70% sensitivity and 73% specificity for identifying CAD, while a chemerin cutoff of 90.46 ng/mL had 61% sensitivity and 62% specificity. A strong positive correlation was observed between CTRP5 and chemerin, but neither adipokine showed a correlation with the Agatston score, a measure of CAD severity and extent, nor with coronary artery stenosis as determined by CCTA. …”
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The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey) by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson

“…We confirmed the strong association between SNPs in the 60 kb CVD region with AP, MI, and CHD (P<0.01). …”
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Risk factors for and incidence of osteoporosis in patients with breast cancer by gender : a nationwide cohort study by Jin Ah Lee, Hye Sun Lee, Soyoung Jeon, Dooreh Kim, YoungJoo Lee, SooYun Bae, Woo-Chan Park, Chang Ik Yoon

“…Endocrine therapy increased osteoporosis risk, particularly among females (hazard ratio [HR], 6.37; 95% confidence interval [CI], 3.74–10.89; p < 0.001). Age, steroid use, and CCI score were significant risk factors for osteoporosis. …”
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Impact of Prenatal Stress on Neuroendocrine Programming by Odile Viltart, Christel C. A. Vanbesien-Mailliot

“…Among factors susceptible of contributing to such a deleterious programming, nutrients and hormones, especially steroid hormones, are considered as powerful mediators of the fetal organization since they readily cross the placental barrier. …”
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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

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Efficacy of a new treatment algorithm for capsulitis of the fingers in rock climbers by Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Christoph Lutter, Christoph Lutter, Hans-Christoph Lang, Mario Perl, Othmar Moser, Michael Simon

“…Therapy consisted of either conservative management, steroid injections, radiosynoviorthesis or a combination depending on the treatment regimen, prior therapy and timeline of symptoms. …”
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Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases [version 2; peer review: 2 approved] by Céline Heinl, Ines Schadock, Maximilian Wurm, Paul Lucas Wildner, Daniel Butzke, Bettina Bert, Alexandra Bannach-Brown, Matthias Steinfath, Kai Diederich

“…We compare the results with the age and sex of patients in clinical trials focusing on Alzheimer's disease, stroke, type 2 diabetes mellitus, ischemic heart disease, and chronic obstructive pulmonary disease. …”
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Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis by Hayriye Tatlı Doğan, Mehmet Doğan, Seda Kahraman, Doğukan Çanakçı, Mehmet Ali Nahit Şendur, Mustafa Tahtacı, Fazlı Erdoğan

“…Our study should be supported by more comprehensive studies addressing the tumor stroma and its prognostic importance.…”
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Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway by Wanwipha Woonnoi, Lalita Chotphruethipong, Supita Tanasawet, Soottawat Benjakul, Nuthathai Sutthiwong, Wanida Sukketsiri

“…After 24 h of incubation, keratinocyte proliferation was detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and double stranded DNA (dsDNA) assays, and by determining the total cellular protein content. …”
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Influence of light intensity, pre-harvest fasting, and storage time on biochemical components in serum and plasma of broilers by Clauber Polese, Lucas Wachholz, Cleison de Souza, Nilton Rohloff Junior, Guilherme Luis Silva Tesser, Rayanne Andrade Nunes, Cinthia Eyng, Jessica Dawn Starkey, Charles William Starkey, Jansller Luiz Genova, Ricardo Vianna Nunes

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β-Nicotinamide Mononucleotide Reduces Oxidative Stress and Improves Steroidogenesis in Granulosa Cells Associated with Sheep Prolificacy via Activating AMPK Pathway by Yu Cai, Hua Yang, Hui Xu, Shanglai Li, Bingru Zhao, Zhibo Wang, Xiaolei Yao, Feng Wang, Yanli Zhang

“…Importantly, NMN treatment improved the impairments in steroid hormone levels induced by LPS. Mechanistically, the protective effects of NMN against GCs function were mediated via the AMPK/mTOR pathway. …”
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