Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential by Mi-bo Tang, Yi-xuan Liu, Zheng-wei Hu, Hai-yang Luo, Shuo Zhang, Chang-he Shi, Yu-ming Xu, Yu-ming Xu, Yu-ming Xu

“…Furthermore, we present the role of PGC-1α in the pathogenesis of various neurological diseases, such as intracerebral hemorrhage, ischemic stroke, Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis, Huntington’s disease, and other PolyQ diseases. …”
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The Neutrophil-to-Lymphocyte Ratio is Associated with the Requirement and the Duration of Invasive Mechanical Ventilation in Acute Respiratory Distress Syndrome Patients: A Retrosp... by Lijuan Yang, Chang Gao, Ying He, Xiaowan Wang, Ling Yang, Shiqi Guo, Jiahao Chen, Siyu He, Yuanxiao Sun, Ye Gao, Qiang Guo

“…Furthermore, logistic regression analysis was used to screen the independent risk factors for IMV. STROBE checklist was used for this manuscript. Results. 520 ARDS patients were included and the median NLR value in IMV group was significantly higher than that of other groups (P<0.001). …”
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Effect of Change in Material Properties of the Abradable Coating on the Wear Behavior of It—Microstructure Model-Based Analysis Approach by Anitha Kumari Azmeera, Prakash Jadhav, Chhaya Lande

“…Furthermore, altering the Young’s modulus of the shroud material achieves optimal abradability when tangent modulus and yield stress remain constant. …”
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Application of low-cost hydrokinetic technology for accelerating electricity access to rural areas in developing economies: field experiment in Kenya by Willis Awandu, Jens-Uwe Wiesemann, Boris Lehmann

“…A decommissioned boat motor with a 0.24 m diameter rotor is operated as a turbine. A shroud for flow acceleration was developed from 1.5 mm thick stainless-steel plates and a support structure constructed using angle lines. …”
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Novel PITX2 Mutations including a Mutation Causing an Unusual Ophthalmic Phenotype of Axenfeld-Rieger Syndrome by Liqin Huang, Yong Meng, Xiangming Guo

“…Analysis of mutations in control subjects was performed by heteroduplex single-strand conformation polymorphism (SSCP) analysis. …”
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Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

“…Image analysis of the gluten network revealed that fibre structure and physico-chemical properties influenced the gluten network by altering branching rate, lacunarity, and protein strand width. Comparing inulins and polydextrose of similar molecular weights (Mw) indicated that interactions with gluten were influenced more by NOH,s than Mw. …”
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Dependence of the content of starch and reducing sugars on the level of expression of the genes of β-amylases StBAM1 and StBAM9 and the amylase inhibitor StAI during long-term low-... by A. V. Kulakova, G. I. Efremov, A. V. Shchennikova, E. Z. Kochieva

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Comparative analysis of consistency of adaptations to interval interventions individualized using sport-specific techniques in well-trained soccer players by Hongjun Zhang, Sheng Li, Bingyuan Yang

“…There was no significant difference between HIITvIFT and SSG in cardiac hemodynamics (cardiac output and stroke volume). Overall, by facilitating more homogenous stress, HIITvIFT results in more identical physiological demands and more uniform adaptations in ventilatory threshold and anaerobic power than SSG.…”
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Inhibitory Effect of Cinobufagin on L-Type Ca2+ Currents, Contractility, and Ca2+ Homeostasis of Isolated Adult Rat Ventricular Myocytes by Pinya Li, Qiongtao Song, Tao Liu, Zhonglin Wu, Xi Chu, Xuan Zhang, Ying Zhang, Yonggang Gao, Jianping Zhang, Li Chu

“…Cinobufagin (CBG), a major bioactive ingredient of the bufanolide steroid compounds of Chan Su, has been widely used to treat coronary heart disease. …”
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Bibliometric analysis of holographic data storage literature by K. Kumar, R. Parameswaran

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Examining anti-inflammatory therapies in the prevention of cardiovascular events: protocol for a systematic review and network meta-analysis of randomised controlled trials by George A Wells, Kevin Emery Boczar, Sheojung Shin, Kathryn A Bezzina, Aishwarya Geejo, Alexander Liam Pearson, Saba Shahab, Christophe A Fehlmann, Sarah Visintini, Rob Beanlands

“…These include (but are not limited to): non-steroidal anti-inflammatory drugs (NSAIDs), colchicine, prednisone, methotrexate, canakinumab, pexelizumab, anakinra, succinobucol, losmapimod, inclacumab, atreleuton, LP-PLA2 (darapladib) and sPLA2 (varespladib). …”
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Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow by Bianca Leistner, Dominic Rauschning, Ralf Matthias Hagen, Franziska Srečec, Nico Tom Mutters, Ruth Weppler, Christina Mutschnik, Manuel Döhla

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Safety and efficacy of apixaban versus vitamin K antagonists in patients undergoing dialysis: a systematic review and meta-analysis by Yifang Zhang, Jialiang Wang, Nannan Shen, Jie Jiang, Yanna Xie

“…Meta-analysis showed no difference in the risk of ischemic stroke (RR: 0.40, 95% CI: 0.06, 2.69, I2 = 0%), mortality (RR: 1.26, 95% CI: 0.74, 2.16, I2 = 94%) and recurrent venous thromboembolism (RR: 1.02, 95% CI: 0.87, 1.21, I2 = 0%) between the two groups. …”
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The eradication of pea weevil Bruchus pisorum (L.) (Coleoptera: Chrysomelidae) from New Zealand by David G. Voice, Rory MacLellan, Adrian Russell, Dave Goulden, Ivan Lawrie, Greg Baker, David A. J. Teulon, John M. Kean

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Fish Tank Granuloma Presenting as a Nasal Cavity Mass by Motoki Sekine, Fumiyuki Goto, Kosuke Saito, Shoji Kaneda, Hikaru Yamamoto, Tomoaki Murakami, Takahide Hamano, Kenji Okami

“…Since the application of steroid ointment did not reduce the size of the mass, the tumor was resected under local anesthesia, and the base was cauterized. …”
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Effects of Oral L-Carnitine Supplementation on Lipid Profile, Anemia, and Quality of Life in Chronic Renal Disease Patients under Hemodialysis: A Randomized, Double-Blinded, Placeb... by Afsoon Emami Naini, Mahnaz Moradi, Mojgan Mortazavi, Asghar Amini Harandi, Mehdi Hadizadeh, Farhad Shirani, Hamed Basir Ghafoori, Pardis Emami Naini

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Physicochemical, rheological and antioxidant profiling of yogurt prepared from non-enzymatically and enzymatically hydrolyzed potato powder under refrigeration by Ishtiaq Ahmad, Zhouyi Xiong, Hanguo Xiong, Rana Muhammad Aadil, Nauman Khalid, Allah Bakash Jvaid Lakhoo, Zia-ud-din, Asad Nawaz, Noman Walayat, Rao Sanaullah Khan

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Combination therapy of intravitreal ranibizumab and sub-tenon triamcinolone for treatment of resistant diabetic macular edema: a clinical study in Egypt by Hossam Eldin M. A. Khalil, Hazem E. Haroun, Alaa A. I. Shalan, Waleed M. Mahran

“…This research was to examine the efficacy of sub-tenon steroid and anti- vascular endothelial growth factor (VEGF) injections as a combination therapy for the treatment of resistant DME, owing to the synergistic effect of this combination. …”
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Valuable agronomic traits of chufa (<i>Cyperus esculentus</i> L.) accessions from the VIR collection: methods of preparing nodules for long-term storage by N. G. Kon’kova, G. F. Safina

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Contemporary Management of Patent Foramen Ovale: A Multinational Survey on Cardiologists’ Perspective by Maciej Dębski, Amr Abdelrahman, Halia Alshehri, Marloe Prince, Andrew Wiper, Shajil Chalil, Dariusz Dudek, Christopher J. White, David Hildick-Smith, David H. Roberts

“…Significant differences between regions were noted in the duration of ECG monitoring during the diagnostic process, PFO closure for left circulation thromboembolism other than stroke/transient ischemic attack, and intraoperative use of intracardiac echocardiography. …”
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